Fludarabine and acute graft versus host disease 
Fludarabine and acute graft versus host disease Patient Reports February 12, 2012
Fludarabine Side Effects Report #5811440-8
Fludarabine side effect was reported by a Health Professional from PORTUGAL on July 02, 2008. Male patient, 53 years of age, was diagnosed with stem cell transplant, graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, anaemia, cytomegalovirus infection
, glomerulonephritis minimal lesion, lichenoid keratosis, meningioma, nephrotic syndrome, poikiloderma, rash maculo-papular. Fludarabine dosage: unknown. During the same period patient was treated with BUSULFAN, CYCLOSPORINE, ENALAPRIL MALEATE, BISOPROLOL FUMARATE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ACYCLOVIR, MIANSERINE, FOLATE. Patient recovered.Fludarabine Side Effects Report #5850961-9
Fludarabine side effect was reported by a Health Professional from BRAZIL on Aug 08, 2008. Male patient, 31 years of age, was diagnosed with stem cell transplant, immunosuppression and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, acute graft versus host disease in intestine, acute graft versus host disease in skin, diarrhoea, lower gastrointestinal haemorrhage, mucosal inflammation, rash maculo-papular. Fludarabine dosage: unknown. During the same period patient was treated with BUSULFAN, CYCLOSPORINE, METHOTREXATE. Patient recovered.
Fludarabine Side Effects Report #5782833-2
Fludarabine side effect was reported by a Health Professional from GERMANY on June 14, 2008. Male patient, 21 years of age, was diagnosed with stem cell transplant, aplastic anaemia, prophylaxis, antifungal prophylaxis, antiviral prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, THYMOGLOBULIN, CYCLOSPORINE, STEROIDS, FLUORCHINOLONE PROPHYLAXIS, PENTAMIDINE, TRIMETHOPRIM, ACYCLOVIR. Patient recovered.
Fludarabine Side Effects Report #5664257-1
Fludarabine side effect was reported by a Consumer or non-health professional from GERMANY on Feb 27, 2008. Female patient was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease. Fludarabine dosage: TOTAL DAILY DOSE: 30 MG/M2. During the same period patient was treated with THIOTEPA. Patient died.
Fludarabine Side Effects Report #5901857-5
Fludarabine side effect was reported by a Health Professional from JAPAN on Jan 18, 2008. Male patient, 31 years of age, was diagnosed with preoperative care, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, acute monocytic leukaemia, chronic graft versus host disease, sepsis
. Fludarabine dosage: unknown. During the same period patient was treated with BUSULFAN, MYCOPHENOLATE MOFETIL, CYCLOSPORINE, PREDNISOLONE. Patient died.Fludarabine Side Effects Report #5693431-3
Fludarabine side effect was reported by a Physician from UNITED STATES on Mar 07, 2008. Female patient was diagnosed with myelodysplastic syndrome, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, chronic graft versus host disease, infection
. Fludarabine dosage: TOTAL DAILY DOSE: 25 MG/M2 UNIT DOSE: 25 MG/M2. During the same period patient was treated with BUSULFAN, MELPHALAN, ANTITHYMOCYTE IMMUNOGLOBULIN. Patient died.Fludarabine Side Effects Report #5690052-3
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 07, 2008. Female patient was diagnosed with haematological malignancy and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, chronic graft versus host disease, infection
, multi-organ failure, respiratory failure. Fludarabine dosage: TOTAL DAILY DOSE: 160 MG/M2 UNIT DOSE: 160 MG/M2. During the same period patient was treated with MELPHALAN, THIOTEPA, THYMOGLOBULIN. Patient died.Fludarabine Side Effects Report #5579066-1
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Dec 07, 2007. Male patient, child 9 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, acute graft versus host disease in skin, viral haemorrhagic cystitis. Fludarabine dosage: unknown. During the same period patient was treated with NEUPOGEN, ACYCLOVIR. Patient recovered.
Fludarabine Side Effects Report #5819364-7
Fludarabine side effect was reported by a Health Professional from FRANCE on July 11, 2008. Male patient, 49 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, infection
. Fludarabine dosage: unknown. Patient died.Fludarabine Side Effects Report #6119893-5
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Mar 03, 2009. Male patient, 37 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, epstein-barr virus associated lymphoproliferative disorder. Fludarabine dosage: unknown. During the same period patient was treated with ANTILYMPHOCYTE IMMUNOGLOBULIN, CYCLOSPORINE, CYCLOPHOSPHAMIDE. Patient died.
Fludarabine Side Effects Report #5795845-X
Fludarabine side effect was reported by a Health Professional from GERMANY on June 17, 2008. Female patient, 17 years of age, was diagnosed with bone marrow conditioning regimen, immunosuppression and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, epstein-barr virus infection, lymphoproliferative disorder. Fludarabine dosage: unknown. During the same period patient was treated with ETOPOSIDE, PREDNISOLONE, ETANERCEPT, CYCLOSPORINE, MYCOPHENOLATE MOFETIL. Patient died.
Fludarabine Side Effects Report #5640856-8
Fludarabine side effect was reported by a Health Professional from POLAND on Feb 20, 2008. Female patient, child 11 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, neurotoxicity. Fludarabine dosage: unknown. During the same period patient was treated with TREOSULFAN. Patient died.
Fludarabine Side Effects Report #5904191-2
Fludarabine side effect was reported by a Health Professional from JAPAN on Sept 18, 2008. Male patient, child 5 years of age, was diagnosed with prophylaxis against graft versus host disease, convulsion prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, epstein-barr virus associated lymphoproliferative disorder, staphylococcal sepsis. Fludarabine dosage: unknown. During the same period patient was treated with BUSULFAN, CYCLOPHOSPHAMIDE, TACROLIMUS, METHOTREXATE, NEUPOGEN, HEPARIN, ANTICONVULSANTS. Patient died on 01/01/2006.
Fludarabine Side Effects Report #5904219-X
Fludarabine side effect was reported by a Health Professional from JAPAN on Sept 18, 2008. Male patient, child 5 years of age, was diagnosed with prophylaxis against graft versus host disease, convulsion prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, streptococcal sepsis. Fludarabine dosage: unknown. During the same period patient was treated with BUSULFAN, CYCLOPHOSPHAMIDE, TACROLIMUS, METHOTREXATE, NEUPOGEN, HEPARIN, ANTICONVULSANTS. Patient recovered.
Fludarabine Side Effects Report #5932366-5
Fludarabine side effect was reported by a Health Professional from JAPAN on Oct 17, 2008. Male patient, child 5 years of age, was diagnosed with prophylaxis against graft versus host disease, cardiovascular event prophylaxis, convulsion prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, epstein-barr virus associated lymphoproliferative disorder, staphylococcal sepsis. Fludarabine dosage: unknown. During the same period patient was treated with BUSULFAN, CYCLOPHOSPHAMIDE, TACROLIMUS, METHOTREXATE, NEUPOGEN, HEPARIN, ANTICONVULSANTS. Patient died on 01/01/2006.
Fludarabine Side Effects Report #5952921-6
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 10, 2008. Female patient, child 3 years of age, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, adenoviral hepatitis, evans syndrome. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOSPORINE, CYCLOPHOSPHAMIDE, TREOSULFAN. Patient died.
Fludarabine Side Effects Report #5954783-X
Fludarabine side effect was reported by a Health Professional from UNITED KINGDOM on Nov 07, 2008. Female patient, child 3 years of age, was diagnosed with prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, adenoviral hepatitis, evans syndrome. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOSPORINE, CYCLOPHOSPHAMIDE, TREOSULFAN. Patient died.
Fludarabine Side Effects Report #5961739-X
Fludarabine side effect was reported by a Health Professional from UNITED KINGDOM on Nov 13, 2008. Female patient, child 3 years of age, was diagnosed with prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, adenoviral hepatitis, evans syndrome. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOSPORINE, CYCLOPHOSPHAMIDE, TREOSULFAN. Patient died.
Fludarabine Side Effects Report #5468605-7
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on Sept 19, 2007. Male patient, child 12 years of age, was diagnosed with chronic myeloid leukaemia, stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, bone marrow failure, stomatitis. Fludarabine dosage: TOTAL: 125 MG/M2. During the same period patient was treated with MELPHALAN, GLEEVEC, METHOTREXATE, CYCLOSPORINE. Patient recovered.
Fludarabine Side Effects Report #5657071-4
Fludarabine side effect was reported by a Consumer or non-health professional from GERMANY on Feb 27, 2008. Female patient was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease. Fludarabine dosage: TOTAL DAILY DOSE: 30 MG/M2. During the same period patient was treated with THIOTEPA. Patient died.
Fludarabine Side Effects Report #5850831-6
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on Aug 02, 2008. Female patient was diagnosed with antibiotic prophylaxis, prophylaxis against graft versus host disease, antiviral prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, chronic graft versus host disease, cytomegalovirus infection
, diarrhoea, encephalitis herpes, hepatotoxicity, interstitial lung disease, multi-organ failure, pneumonia . Fludarabine dosage: TOTAL DAILY DOSE: 150 MG/M2. During the same period patient was treated with NEUPOGEN, CIPROFLOXACIN, CYCLOSPORINE, TACROLIMUS, METHOTREXATE, ACYCLOVIR. Patient died.Fludarabine Side Effects Report #5852769-7
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on Aug 02, 2008. Female patient was diagnosed with antibiotic prophylaxis, prophylaxis against graft versus host disease, antiviral prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, chronic graft versus host disease, cytomegalovirus infection
, diarrhoea, encephalitis herpes, hepatotoxicity, interstitial lung disease, multi-organ failure, pneumonia . Fludarabine dosage: TOTAL DAILY DOSE: 150 MG/M2. During the same period patient was treated with NEUPOGEN, CIPROFLOXACIN, CYCLOSPORINE, TACROLIMUS, METHOTREXATE, ACYCLOVIR. Patient died.