Fludarabine and acute graft versus host disease in skin Patient Reports February 12, 2012

Fludarabine Side Effects Report #5933642-2
Fludarabine side effect was reported by a Health Professional from INDIA on Oct 20, 2008. Male patient, 37 years of age, was diagnosed with stem cell transplant, chronic graft versus host disease, prophylaxis against graft versus host disease, aplastic anaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in liver, acute graft versus host disease in skin, chronic graft versus host disease, disseminated tuberculosis, fungal sepsis, leukopenia, multi-organ failure, pyrexia, respiratory failure. Fludarabine dosage: unknown. During the same period patient was treated with PREDNISOLONE, CYCLOPHOSPHAMIDE, ATGAM, MYCOPHENOLATE MOFETIL, CYCLOSPORINE, METHOTREXATE. Patient was hospitalized. Patient died.

Fludarabine Side Effects Report #5971741-X
Fludarabine side effect was reported by a Health Professional from GERMANY on Nov 18, 2008. Female patient, 36 years of age, was diagnosed with stem cell transplant, prophylaxis against graft versus host disease, immunosuppression and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, febrile neutropenia, fungus serology test positive, fusarium infection, hepatic function abnormal, liver abscess, lung infiltration, skin nodule. Fludarabine dosage: unknown. During the same period patient was treated with ANTITHYMOCYTE GLOBULINE, CYCLOSPORINE, METHOTREXATE, MYCOPHENOLATE MOFETIL, TACROLIMUS, PREDNISOLONE. Patient died on 11/01/2006.

Fludarabine Side Effects Report #5850961-9
Fludarabine side effect was reported by a Health Professional from BRAZIL on Aug 08, 2008. Male patient, 31 years of age, was diagnosed with stem cell transplant, immunosuppression and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, acute graft versus host disease in intestine, acute graft versus host disease in skin, diarrhoea, lower gastrointestinal haemorrhage, mucosal inflammation, rash maculo-papular. Fludarabine dosage: unknown. During the same period patient was treated with BUSULFAN, CYCLOSPORINE, METHOTREXATE. Patient recovered.

Fludarabine Side Effects Report #5796255-1
Fludarabine side effect was reported by a Health Professional from GERMANY on June 18, 2008. Male patient, 21 years of age, was diagnosed with stem cell transplant, cytomegalovirus infection , prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, cytomegalovirus infection , encephalitis viral, fungal infection , herpes virus infection, human polyomavirus infection, weight decreased. Fludarabine dosage: unknown. During the same period patient was treated with FOSCARNET, CYCLOSPORINE, MOFETIL, ACYCLOVIR. Patient was hospitalized. Patient died.


Fludarabine Side Effects Report #5797729-X
Fludarabine side effect was reported by a Health Professional from GERMANY on June 18, 2008. Male patient, 21 years of age, was diagnosed with stem cell transplant, cytomegalovirus infection , prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, cytomegalovirus infection , encephalitis viral, fungal infection , herpes virus infection, human polyomavirus infection, weight decreased. Fludarabine dosage: unknown. During the same period patient was treated with FOSCARNET, CYCLOSPORINE, MOFETIL, ACYCLOVIR. Patient was hospitalized. Patient died.

Fludarabine Side Effects Report #5532973-8
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Nov 29, 2007. Male patient, weighting 209.4 lb, was diagnosed with chronic myelomonocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in intestine, acute graft versus host disease in skin, bacteraemia, renal failure, respiratory disorder, urinary tract infection enterococcal. Fludarabine dosage: unknown. During the same period patient was treated with BUSULFAN, CAMPATH. Patient died on 11/23/2007.

Fludarabine Side Effects Report #5361557-X
Fludarabine side effect was reported by a Health Professional from ITALY on June 12, 2007. Female patient, child 9 years of age, was diagnosed with bone marrow transplant  and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, areflexia, convulsion, coordination abnormal, diplopia, haemolytic anaemia, miller fisher syndrome. Fludarabine dosage: unknown. During the same period patient was treated with ATGAM, CYCLOPHOSPHAMIDE, METHOTREXATE, CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #5579066-1
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Dec 07, 2007. Male patient, child 9 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, acute graft versus host disease in skin, viral haemorrhagic cystitis. Fludarabine dosage: unknown. During the same period patient was treated with NEUPOGEN, ACYCLOVIR. Patient recovered.

Fludarabine Side Effects Report #5618328-6
Fludarabine side effect was reported by a Health Professional from SWEDEN on Jan 22, 2008. Male patient, 61 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in liver, acute graft versus host disease in skin, chronic graft versus host disease, genital lesion, lichenification. Fludarabine dosage: unknown. During the same period patient was treated with BUSULPHAN, CYCLOSPORINE, METHOTREXATE. Patient recovered.


Fludarabine Side Effects Report #5618724-7
Fludarabine side effect was reported by a Health Professional from SWEDEN on Jan 22, 2008. Male patient, 61 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in liver, acute graft versus host disease in skin, chronic graft versus host disease, genital lesion, lichenification. Fludarabine dosage: unknown. During the same period patient was treated with BUSULPHAN, CYCLOSPORINE, METHOTREXATE. Patient recovered.

Fludarabine Side Effects Report #5821690-2
Fludarabine side effect was reported by a Health Professional from SPAIN on July 15, 2008. Male patient, 38 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, acute myocardial infarction, antiphospholipid syndrome, pneumonia cytomegaloviral. Fludarabine dosage: unknown. During the same period patient was treated with MELPHALAN, CYCLOSPORINE, METHOTREXATE. Patient recovered.

Fludarabine Side Effects Report #5524696-6
Fludarabine side effect was reported by a Physician from SWITZERLAND on Nov 19, 2007. Male patient, 28 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in intestine, acute graft versus host disease in skin, arthritis bacterial, bone marrow failure, bronchopulmonary aspergillosis, chronic graft versus host disease, cytomegalovirus infection , hypogammaglobulinaemia, pneumonitis. Fludarabine dosage: unknown. During the same period patient was treated with METHOTREXATE, CYCLOSPORINE, PREDNISONE, RITUXIMAB, ETOPOSIDE, CARMUSTINE, CYTARABINE. Patient recovered.

Fludarabine Side Effects Report #5738634-4
Fludarabine side effect was reported by a Health Professional from GERMANY on May 06, 2008. Male patient was diagnosed with b-cell small lymphocytic lymphoma and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, progressive multifocal leukoencephalopathy. Fludarabine dosage: AS USED: 25 MG/M2. During the same period patient was treated with FLUDARABINE PHOSPHATE, ALEMTUZUMAB, PREDNISONE, CYCLOPHOSPHAMIDE, VINCRISTINE. Patient was hospitalized. Patient died.

Fludarabine Side Effects Report #5069810-4
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 13, 2006. Female patient, 16 years of age, was diagnosed with aplastic anaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, anaemia haemolytic autoimmune, aplastic anaemia, bone marrow disorder, disease recurrence, pancytopenia, renal failure, viral infection . Fludarabine dosage: unknown. During the same period patient was treated with CAMPATH, CYCLOPHOSPHAMIDE, CYCLOSPORINE, CORTICOSTEROIDS. Patient recovered.


Fludarabine Side Effects Report #5479816-9
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on Sept 27, 2007. Male patient, child 12 years of age, was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, rash , stomatitis. Fludarabine dosage: 25 MG/M2. During the same period patient was treated with MELPHALAN, METHOTREXATE, SANDIMMUNE. Patient recovered.