Fludara and malignant neoplasm progression Patient Reports February 12, 2012

Fludara Side Effects Report #5821689-6
Fludara side effect was reported by a Physician from RUSSIAN FEDERATION on July 18, 2008. Male patient, 58 years of age, was diagnosed with non-hodgkin's lymphoma, prophylaxis, prophylaxis of nausea and vomiting, antiviral prophylaxis and was treated with Fludara. After drug was administered, patient experienced the following side effects: haemorrhage, haemorrhagic infarction, malignant neoplasm progression, thrombocytopenia. Fludara dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, ALLOPURINOL, ONDANSETRON, IMMUNE GLOBULIN INTRAVENOUS. Patient died on 06/08/2008.

Fludara Side Effects Report #5147206-4
Fludara side effect was reported by a Health Professional from UNITED STATES on Nov 01, 2006. Male patient, 75 years of age, weighting 153.0 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludara. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia, malignant neoplasm progression, stevens-johnson syndrome. Fludara dosage: 25 MG/M2, INTRAVENOUS. During the same period patient was treated with PREVACID, FOSAMAX, ASCORBIC ACID, DANAZOL, LOPRESSOR, COLACE, FLOMAX. Patient died on 04/01/2006.

Fludara Side Effects Report #4715614-9
Fludara side effect was reported by a Consumer or non-health professional from FRANCE on July 08, 2005. Male patient, 62 years of age, weighting 187.4 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludara. After drug was administered, patient experienced the following side effects: cholestasis, cough, cytolytic hepatitis, focal nodular hyperplasia, hepatic function abnormal, lymphocytosis, malignant neoplasm progression, monocyte count increased, neutropenia. Fludara dosage: 30 MG/M2, 2 CYCLES X 5D, ORAL. During the same period patient was treated with CYCLOPHOSPHAMIDE, ZOPHREN, LEXOMIL, OMEPRAZOLE, STILNOX, PAROXETINE HYDROCHLORIDE, CORTANCYL, TRANSIPEG. Patient was hospitalized. Patient died on 10/27/2002.

Fludara Side Effects Report #4822089-8
Fludara side effect was reported by a Physician from JAPAN on Oct 19, 2005. Male patient, 58 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludara. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia, immune system disorder, malignant neoplasm progression. Fludara dosage: unknown. Patient was hospitalized. Patient recovered.


Fludara Side Effects Report #4907252-X
Fludara side effect was reported by a Physician from UNITED STATES on Jan 25, 2006. Male patient, 51 years of age, weighting 238.1 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludara. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, b-cell small lymphocytic lymphoma, blood lactate dehydrogenase increased, chronic lymphocytic leukaemia, ischaemia, laboratory test interference, lymphadenopathy, malignant neoplasm progression, myocardial infarction. Fludara dosage: unknown. During the same period patient was treated with RITUXIMAB, CYCLOPHOSPHAMIDE, VALTREX, ALLEGRA, KETOCONAZOLE, SEPTRA DS. Patient was hospitalized. Patient recovered.

Fludara Side Effects Report #5081636-4
Fludara side effect was reported by a Consumer or non-health professional from GERMANY on July 26, 2006. Female patient was diagnosed with breast cancer metastatic and was treated with Fludara. After drug was administered, patient experienced the following side effects: malignant neoplasm progression, metastases to liver, metastases to lung, pulmonary embolism . Fludara dosage: unknown. During the same period patient was treated with TAXOL, FLUOROURACIL, EPIRUBICIN, MITOMYCIN, VINORELBINE TARTRATE. Patient recovered.

Fludara Side Effects Report #4987398-0
Fludara side effect was reported by a Physician from UNITED STATES on Apr 07, 2006. Male patient, 69 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: febrile neutropenia, graft versus host disease, malignant neoplasm progression, mental status changes, pancytopenia, somnolence, venoocclusive liver disease. Fludara dosage: 30 MG/M2, 1X/DAY D-7 THROUGH D-2, INTRAVENOUS. During the same period patient was treated with BUSULFAN, ANTITHYMOCYTE, CYCLOSPORINE, METHOTREXATE, FLUCONAZOLE, GRANULOCYTE COLONY STIMULATING FACTOR, ANTIINFECTIVES. Patient died.

Fludara Side Effects Report #5041959-1
Fludara side effect was reported by a Physician from UNITED STATES on June 15, 2006. Male patient, 62 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, graft versus host disease in skin, malignant neoplasm progression, squamous cell carcinoma of skin. Fludara dosage: 125 MG/M2, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE. Patient died.

Fludara Side Effects Report #4960095-3
Fludara side effect was reported by a Physician from UNITED STATES on Mar 14, 2006. Male patient, 42 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: aspergillosis, disease progression, flushing, graft versus host disease, malignant neoplasm progression, mastocytosis, nausea , type iv hypersensitivity reaction. Fludara dosage: 25 MG/M2 D-5 TO D, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient died on 01/01/2001.


Fludara Side Effects Report #6073396-5
Fludara side effect was reported by a Consumer or non-health professional from JAPAN on Jan 27, 2009. Male patient, 68 years of age, was treated with Fludara. After drug was administered, patient experienced the following side effects: hepatic function abnormal, malignant neoplasm progression. Fludara dosage: 60 MG ORAL. During the same period patient was treated with CYCLOPHOSPHAMIDE. Patient died.

Fludara Side Effects Report #5420085-3
Fludara side effect was reported by a Health Professional from JAPAN on Aug 09, 2007. Female patient, 13 years of age, was diagnosed with prophylaxis against graft versus host disease and was treated with Fludara. After drug was administered, patient experienced the following side effects: ascites, bone sarcoma, malignant neoplasm progression, malignant pleural effusion, pleural haemorrhage, pulmonary oedema, respiratory failure. Fludara dosage: 30 MG/M2, 1X/DAY. During the same period patient was treated with BUSULFAN, CYCLOSPORINE, METHOTREXATE. Patient died on 05/25/2003.