Fludara and graft versus host disease Patient Reports February 12, 2012

Fludara Side Effects Report #6101150-4
Fludara side effect was reported by a Health Professional from JAPAN on Feb 26, 2009. Female patient, 42 years of age, weighting 116.8 lb, was diagnosed with myelodysplastic syndrome, stem cell transplant, prophylaxis against graft versus host disease and was treated with Fludara. After drug was administered, patient experienced the following side effects: graft versus host disease, sepsis , thrombotic microangiopathy. Fludara dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL. Patient died on 04/12/2008.

Fludara Side Effects Report #6119100-3
Fludara side effect was reported by a Health Professional from JAPAN on Mar 10, 2009. Female patient, 42 years of age, weighting 116.8 lb, was diagnosed with myelodysplastic syndrome, stem cell transplant, prophylaxis against graft versus host disease and was treated with Fludara. After drug was administered, patient experienced the following side effects: graft versus host disease, sepsis , thrombotic microangiopathy. Fludara dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL. Patient died on 04/12/2008.

Fludara Side Effects Report #5253455-7
Fludara side effect was reported by a Health Professional from on Feb 15, 2007. Male patient, 58 years of age, was diagnosed with chronic lymphocytic leukaemia, anaemia and was treated with Fludara. After drug was administered, patient experienced the following side effects: febrile neutropenia, graft versus host disease, multi-organ failure. Fludara dosage: unknown. During the same period patient was treated with RED BLOOD CELLS. Patient was hospitalized. Patient died.

Fludara Side Effects Report #4569642-7
Fludara side effect was reported by a Physician from on Jan 19, 2005. Female patient, 41 years of age, weighting 123.5 lb, was diagnosed with bone marrow transplant  and was treated with Fludara. After drug was administered, patient experienced the following side effects: cholangitis, gastrointestinal disorder, graft versus host disease, haemolytic anaemia, hallucination, hepatic encephalopathy, hepatic failure, liver disorder, loss of consciousness. Fludara dosage: unknown. During the same period patient was treated with CYTARABINE, ETOPOSIDE, CYCLOPHOSPHAMIDE, MYCOPHENOLATE MOFETIL, METHOTREXATE, METHYLPREDNISOLONE. Patient was hospitalized. Patient died on 11/10/2004.


Fludara Side Effects Report #4987398-0
Fludara side effect was reported by a Physician from UNITED STATES on Apr 07, 2006. Male patient, 69 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: febrile neutropenia, graft versus host disease, malignant neoplasm progression, mental status changes, pancytopenia, somnolence, venoocclusive liver disease. Fludara dosage: 30 MG/M2, 1X/DAY D-7 THROUGH D-2, INTRAVENOUS. During the same period patient was treated with BUSULFAN, ANTITHYMOCYTE, CYCLOSPORINE, METHOTREXATE, FLUCONAZOLE, GRANULOCYTE COLONY STIMULATING FACTOR, ANTIINFECTIVES. Patient died.

Fludara Side Effects Report #4987403-1
Fludara side effect was reported by a Physician from UNITED STATES on Apr 07, 2006. Male patient, 59 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: graft versus host disease, hepatotoxicity, hyperbilirubinaemia. Fludara dosage: 30 MG/M2, 1X/DAY D-7 THROUGH D-2, INTRAVENOUS. During the same period patient was treated with BUSULFAN, ANTITHYMOCYTE IMMUNOGLOBULIN, CYCLOSPORINE, METHOTREXATE, FLUCONAZOLE, GRANULOCYTE COLONY STIMULATING FACTOR, ANTIINFECTIVES. Patient died.

Fludara Side Effects Report #5041961-X
Fludara side effect was reported by a Physician from UNITED STATES on June 15, 2006. Male patient, 59 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: graft versus host disease, graft versus host disease in intestine, graft versus host disease in skin, malignant melanoma stage ii, obliterative bronchiolitis. Fludara dosage: 125 MG/M2, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE. Patient recovered.

Fludara Side Effects Report #4987405-5
Fludara side effect was reported by a Physician from UNITED STATES on Apr 07, 2006. Male patient, 55 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: disseminated cytomegaloviral infection, graft versus host disease. Fludara dosage: 30 MG/M2, 1X/DAY D-7 THROUGH D-2, INTRAVENOUS. During the same period patient was treated with BUSULFAN, ANTITHYMOCYTE IMMUNOGLOBULIN, CYCLOSPORINE, METHOTREXATE, FLUCONAZOLE, GRANULOCYTE COLONY STIMULATING FACTOR, ANTIINFECTIVES. Patient died.

Fludara Side Effects Report #5041966-9
Fludara side effect was reported by a Physician from UNITED STATES on June 15, 2006. Male patient, 53 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: basal cell carcinoma, graft versus host disease, graft versus host disease in skin, malignant melanoma, oral mucosal disorder, stem cell transplant. Fludara dosage: 125 MG/M2, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE. Patient recovered.


Fludara Side Effects Report #4987404-3
Fludara side effect was reported by a Physician from UNITED STATES on Apr 07, 2006. Male patient, 51 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: dialysis , disease progression, graft versus host disease, hepatotoxicity, hyperbilirubinaemia, renal failure. Fludara dosage: 30 MG/M2, 1X/DAY D-7 THROUGH D-2, INTRAVENOUS. During the same period patient was treated with BUSULFAN, ANTITHYMOCYTE IMMUNOGLOBULIN, CYCLOSPORINE, METHOTREXATE, FLUCONAZOLE, GRANULOCYTE COLONY STIMULATING FACTOR, ANTIINFECTIVES. Patient died.

Fludara Side Effects Report #4987401-8
Fludara side effect was reported by a Physician from UNITED STATES on Apr 07, 2006. Male patient, 47 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: graft versus host disease, neoplasm progression, venoocclusive liver disease. Fludara dosage: 30 MG/M2, 1X/DAY D-7 THROUGH D-2, INTRAVENOUS. During the same period patient was treated with BUSULFAN, ANTITHYMOCYTE IMMUNOGLOBULIN, CYCLOSPORINE, METHOTREXATE, FLUCONAZOLE, GRANULOCYTE COLONY STIMULATING FACTOR, ANTIINFECTIVES. Patient died.

Fludara Side Effects Report #5041968-2
Fludara side effect was reported by a Physician from UNITED STATES on June 15, 2006. Male patient, 45 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: basal cell carcinoma, graft versus host disease, graft versus host disease in intestine, graft versus host disease in skin, malignant melanoma, oral mucosal disorder, squamous cell carcinoma of skin. Fludara dosage: 125 MG/M2, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE. Patient recovered.

Fludara Side Effects Report #4960095-3
Fludara side effect was reported by a Physician from UNITED STATES on Mar 14, 2006. Male patient, 42 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludara. After drug was administered, patient experienced the following side effects: aspergillosis, disease progression, flushing, graft versus host disease, malignant neoplasm progression, mastocytosis, nausea , type iv hypersensitivity reaction. Fludara dosage: 25 MG/M2 D-5 TO D, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient died on 01/01/2001.

Fludara Side Effects Report #5253454-5
Fludara side effect was reported by a Health Professional from on Feb 15, 2007. Male patient, 67 years of age, was diagnosed with anaemia and was treated with Fludara. After drug was administered, patient experienced the following side effects: febrile neutropenia, graft versus host disease, multi-organ failure. Fludara dosage: unknown. During the same period patient was treated with RED BLOOD CELLS. Patient was hospitalized. Patient died.


Fludara Side Effects Report #5495040-8
Fludara side effect was reported by a Physician from JAPAN on Oct 10, 2007. Female patient, 40 years of age, was diagnosed with prophylaxis and was treated with Fludara. After drug was administered, patient experienced the following side effects: convulsion, graft versus host disease, histiocytosis haematophagic, liver disorder, sepsis , thrombotic microangiopathy. Fludara dosage: unknown. During the same period patient was treated with MELPHALAN, TACROLIMUS. Patient died.

Fludara Side Effects Report #5484114-3
Fludara side effect was reported by a Physician from UNITED STATES on Oct 02, 2007. Female patient was treated with Fludara. After drug was administered, patient experienced the following side effects: graft versus host disease, lymphopenia, neutropenia. Fludara dosage: 25 MG/M2 DAYS -6 TO -2. During the same period patient was treated with CYCLOPHOSPHAMIDE, DONOR LYMPHOCYTE INFUSION. Patient was hospitalized. Patient died.