Fabrazyme and cardiac arrest Patient Reports February 11, 2012

Fabrazyme Side Effects Report #5226223-X
Fabrazyme side effect was reported by a Physician from JAPAN on Jan 15, 2007. Female patient, 69 years of age, weighting 110.2 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: azotaemia, cardiac arrest , cardiac failure chronic, condition aggravated, disease recurrence, hypotension, mobility decreased, oedema peripheral, renal failure chronic. Fabrazyme dosage: 50 MG Q2WKS IV. During the same period patient was treated with ASPIRIN, SPIRONOLACTONE, FUROSEMIDE. Patient was hospitalized. Patient died on 08/05/2006.

Fabrazyme Side Effects Report #5132615-X
Fabrazyme side effect was reported by a Physician from JAPAN on Oct 03, 2006. Female patient, 69 years of age, weighting 110.2 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , cardiac failure chronic, condition aggravated. Fabrazyme dosage: 50 MG Q2WKS IV. Patient was hospitalized. Patient died on 08/05/2006.

Fabrazyme Side Effects Report #5484496-2
Fabrazyme side effect was reported by a Physician from JAPAN on Sept 26, 2007. Male patient, 64 years of age, weighting 154.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: arrhythmia , cardiac arrest , myocardial infarction. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with DICLOFENAC, BETAMETHASONE, WARFARIN POTASSIUM, ENALAPRIL MALEATE, PRECIPITATED CALCIUM CARBONATE, MECOBALAMIN, ALFACALCIDOL. Patient died on 01/08/2006.

Fabrazyme Side Effects Report #4907133-1
Fabrazyme side effect was reported by a Physician from JAPAN on Jan 23, 2006. Male patient, 64 years of age, weighting 154.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , myocardial infarction. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with APRINDINE HYDROCHLORIDE. Patient died on 01/08/2006.


Fabrazyme Side Effects Report #4917904-3
Fabrazyme side effect was reported by a Physician from JAPAN on Feb 07, 2006. Male patient, 64 years of age, weighting 154.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , feeling abnormal, myocardial infarction. Fabrazyme dosage: 70 MG Q2WS IV. During the same period patient was treated with APRINDINE HYDROCHLORIDE, DICLOFENAC, BETAMETHASONE, WARFARIN POTASSIUM. Patient died on 01/08/2006.

Fabrazyme Side Effects Report #4952174-1
Fabrazyme side effect was reported by a Physician from JAPAN on Mar 08, 2006. Male patient, 64 years of age, weighting 154.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , myocardial infarction. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with APRINDINE HYDROCHLORIDE, DICLOFENAC, BETAMETHASONE, WARFARIN POTASSIUM. Patient died on 01/08/2006.

Fabrazyme Side Effects Report #5500124-1
Fabrazyme side effect was reported by a Physician from JAPAN on Oct 15, 2007. Female patient, 61 years of age, weighting 90.39 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , ventricular fibrillation. Fabrazyme dosage: 40 MG Q2WKS IV. During the same period patient was treated with VALSARTAN, CARVEDILOL. Patient died on 10/05/2007.

Fabrazyme Side Effects Report #6122001-8
Fabrazyme side effect was reported by a Health Professional from UNITED STATES on Mar 02, 2009. Female patient, 59 years of age, weighting 99.21 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest . Fabrazyme dosage: 45 MG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient died on 02/06/2009.

Fabrazyme Side Effects Report #4917901-8
Fabrazyme side effect was reported by a Physician from JAPAN on Feb 06, 2006. Male patient, 58 years of age, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest . Fabrazyme dosage: 50 MG Q2WKS IV. During the same period patient was treated with BETAMETHASONE. Patient died on 02/06/2006.


Fabrazyme Side Effects Report #5029164-6
Fabrazyme side effect was reported by a Physician from ITALY on May 30, 2006. Male patient, 58 years of age, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest . Fabrazyme dosage: unknown. Patient was hospitalized. Patient died on 05/03/2006.

Fabrazyme Side Effects Report #5244223-0
Fabrazyme side effect was reported by a Physician from UNITED KINGDOM on Jan 31, 2007. Male patient, 56 years of age, weighting 136.7 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: blood creatinine increased, brain stem ischaemia, cardiac arrest , coma, condition aggravated, device related infection, encephalopathy, hyperhidrosis, multi-organ failure. Fabrazyme dosage: 1MG/KG Q2WKS; IV. Patient was hospitalized. Patient died on 01/05/2007.

Fabrazyme Side Effects Report #4679767-3
Fabrazyme side effect was reported by a Health Professional from on May 17, 2005. Male patient, 56 years of age, weighting 192.9 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , fall , vestibular disorder. Fabrazyme dosage: 90 MG Q2WKS IV. During the same period patient was treated with THYROXINE, DIGOXIN, FUROSEMIDE, FELODIPINE, WARFARIN, ALPHA CALCIDOL, ALLOPURINOL, RENAGEL. Patient died on 05/15/2005.

Fabrazyme Side Effects Report #4723932-3
Fabrazyme side effect was reported by a Physician from UNITED STATES on July 08, 2005. Male patient, 54 years of age, weighting 150.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: atrial fibrillation , blood pressure immeasurable, cardiac arrest , dizziness , eye rolling, fall , heart rate decreased, hypotension, infusion related reaction. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with TOPROL, COZAAR, ASPIRIN, LIPITOR, GENGRAF, ENALAPRIL MALEATE, CELLCEPT, PREDNISONE. Patient recovered.

Fabrazyme Side Effects Report #4723933-5
Fabrazyme side effect was reported by a Physician from UNITED STATES on July 08, 2005. Male patient, 54 years of age, weighting 150.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: blood pressure increased, cardiac arrest , chills, convulsion, hypotension, infusion related reaction, loss of consciousness, posture abnormal. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with TOPROL, COZAAR, ASPIRIN, LIPITOR, GENGRAF, ENALAPRIL MALEATE, CELLCEPT, PREDNISONE. Patient recovered.


Fabrazyme Side Effects Report #4818846-4
Fabrazyme side effect was reported by a Physician from UNITED STATES on Oct 19, 2005. Male patient, 54 years of age, weighting 150.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: bradycardia, brain stem infarction, cardiac arrest , diarrhoea, hypoxia, loss of consciousness, lung disorder, lung infection, sepsis . Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with BUSPIRONE, PHOSLO, ALLEGRA, LORAZEPAM, VITAMIN B CAP, ASCORBIC ACID, COUMADIN, ACIPHEX. Patient was hospitalized. Patient died on 09/28/2005.

Fabrazyme Side Effects Report #4821748-0
Fabrazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 21, 2005. Male patient, 54 years of age, weighting 150.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , cardiac pacemaker insertion, chills, convulsion, hypotension, infusion related reaction, snoring , somnolence, stridor. Fabrazyme dosage: 70 MG Q2WS IV. During the same period patient was treated with TOPROL, COZAAR, ASPIRIN, LIPITOR, GENGRAF, ENALAPRIL, CELLCEPT, PREDNISONE. Patient recovered.

Fabrazyme Side Effects Report #4826132-1
Fabrazyme side effect was reported by a Physician from UNITED STATES on Oct 31, 2005. Male patient, 54 years of age, weighting 150.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: bradycardia, brain stem infarction, cardiac arrest , diarrhoea, hypoxia, lung infection, sepsis . Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with BUSPIRONE, PHOSLO, ALLEGRA, LORAZEPAM, VITAMIN B CAP, ASCORBIC ACID, COUMADIN, ACIPHEX. Patient was hospitalized. Patient died on 09/28/2005.

Fabrazyme Side Effects Report #4833654-6
Fabrazyme side effect was reported by a Health Professional from UNITED STATES on Nov 04, 2005. Male patient, 54 years of age, weighting 150.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: atrial fibrillation , cardiac arrest , convulsion, dizziness , hypotension, nervous system disorder, somnolence, syncope. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with TOPROL, COZAAR, ASPIRIN, LIPITOR, GENGRAF, ENALAPRIL, CELLCEPT, PREDNISONE. Patient recovered.

Fabrazyme Side Effects Report #4833669-8
Fabrazyme side effect was reported by a Health Professional from UNITED STATES on Nov 04, 2005. Male patient, 54 years of age, weighting 150.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: atrial fibrillation , cardiac arrest , chills, convulsion, dyskinesia, face oedema, flushing, hypotension, infusion related reaction. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with TOPROL, COZAAR, ASPIRIN, LIPITOR, GENGRAF, ENALAPRIL, CELLCEPT, PREDNISONE. Patient recovered.


Fabrazyme Side Effects Report #4865678-7
Fabrazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 06, 2005. Male patient, 54 years of age, weighting 154.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest , condition aggravated, loss of consciousness. Fabrazyme dosage: 70 MG IV. During the same period patient was treated with ASPIRIN, TYLENOL, LIPITOR. Patient died on 12/06/2005.

Fabrazyme Side Effects Report #4952372-7
Fabrazyme side effect was reported by a Health Professional from UNITED STATES on Mar 06, 2006. Male patient, 54 years of age, weighting 150.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: blood pressure increased, cardiac arrest , chills, convulsion, depressed level of consciousness, eye oedema, face oedema, heart rate increased, hypotension. Fabrazyme dosage: unknown. During the same period patient was treated with TOPROL, COZAAR, ASPIRIN, LIPITOR, GENGRAF, ENALAPRIL MALEATE, CELLCEPT. Patient recovered.

Fabrazyme Side Effects Report #5024890-7
Fabrazyme side effect was reported by a Physician from SPAIN on May 24, 2006. Male patient, 54 years of age, weighting 121.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: atrioventricular block complete, cardiac arrest , dizziness , fall , hip fracture, syncope, ventricular arrhythmia. Fabrazyme dosage: 1 MG/KG Q2WKS IV. During the same period patient was treated with DACORTIN, PROGRAF, CELLCEPT, ROCALTROL, FUROSEMIDE, ALDACTONE. Patient died on 05/13/2006.

Fabrazyme Side Effects Report #5444418-7
Fabrazyme side effect was reported by a Health Professional from AUSTRALIA on Aug 23, 2007. Female patient, 52 years of age, weighting 163.4 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: angiopathy, cardiac arrest , infarction. Fabrazyme dosage: 70 MG, IV. Patient was hospitalized. Patient died on 08/17/2007.

Fabrazyme Side Effects Report #5449439-6
Fabrazyme side effect was reported by a Consumer or non-health professional from AUSTRALIA on Aug 31, 2007. Male patient, 52 years of age, weighting 163.1 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: anaesthetic complication cardiac, angiopathy, cardiac arrest , infarction. Fabrazyme dosage: 70 MG IV. During the same period patient was treated with METOPROLOL SUCCINATE, NITROGLYCERIN TRANSDERMAL SYSTEM, CALTRATE, PLAVIX, ALLOPURINOL, MEGAFOL, VITAMIN B6. Patient was hospitalized. Patient died on 08/17/2007.


Fabrazyme Side Effects Report #4888421-4
Fabrazyme side effect was reported by a Health Professional from UNITED STATES on Jan 11, 2006. Male patient, 52 years of age, weighting 164.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: atrial fibrillation , cardiac arrest , disease recurrence. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with WELLBUTRIN, FOSINOPRIL, AMITRIPTYLINE, PULMICORT. Patient was hospitalized. Patient recovered.

Fabrazyme Side Effects Report #4893238-0
Fabrazyme side effect was reported by a Physician from UNITED STATES on Jan 18, 2006. Male patient, 52 years of age, weighting 164.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: atrial fibrillation , cardiac arrest . Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with WELLBUTRIN, FOSINOPRIL, AMITRIPTYLINE, PULMICORT. Patient was hospitalized. Patient recovered.

Fabrazyme Side Effects Report #4909811-7
Fabrazyme side effect was reported by a Physician from UNITED STATES on Jan 25, 2006. Male patient, 52 years of age, weighting 164.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: atrial fibrillation , blood creatinine increased, blood magnesium decreased, blood urea increased, cardiac arrest , disease recurrence, haemoglobin decreased, hypocalcaemia, hypomagnesaemia. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with WELLBUTRIN, FOSINOPRIL, AMITRIPTYLINE, PULMICORT, PROPAFENONE. Patient was hospitalized. Patient recovered.

Fabrazyme Side Effects Report #4973895-0
Fabrazyme side effect was reported by a Physician from UNITED STATES on Apr 05, 2006. Male patient, 52 years of age, weighting 164.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: atrial fibrillation , cardiac arrest , disease recurrence, haemoglobin decreased, hypocalcaemia, hypomagnesaemia, hypoperfusion, renal tubular necrosis, sinus bradycardia. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with WELLBUTRIN, FOSINOPRIL, AMITRIPTYLINE, PULMICORT, PROPAFENONE. Patient was hospitalized. Patient recovered.

Fabrazyme Side Effects Report #5824165-X
Fabrazyme side effect was reported by a Physician from CANADA on July 09, 2008. Male patient, 51 years of age, weighting 180.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: aortic aneurysm , aortic valve disease, atrial fibrillation , atrial flutter, blood creatinine increased, blood pressure systolic decreased, cardiac arrest , large intestine perforation, peritonitis. Fabrazyme dosage: 80 MG, Q2W. During the same period patient was treated with COZAAR, PREDNISOLONE ACETATE, ASPIRIN, LIPITOR. Patient was hospitalized. Patient recovered.


Fabrazyme Side Effects Report #4879827-8
Fabrazyme side effect was reported by a Physician from UNITED STATES on Dec 28, 2005. Male patient, 51 years of age, weighting 250.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest . Fabrazyme dosage: 140 MG Q2WKS IV. During the same period patient was treated with CYCLOSPORINE, LASIX. Patient died on 12/22/2005.

Fabrazyme Side Effects Report #4893237-9
Fabrazyme side effect was reported by a Health Professional from UNITED STATES on Jan 17, 2006. Male patient, 51 years of age, weighting 293.2 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest . Fabrazyme dosage: 105 MG Q2WKS IV. During the same period patient was treated with CYCLOSPORINE, LASIX. Patient died on 12/22/2005.

Fabrazyme Side Effects Report #5227299-6
Fabrazyme side effect was reported by a Health Professional from UNITED STATES on Jan 19, 2007. Male patient, 50 years of age, weighting 117.1 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest . Fabrazyme dosage: 55 MG Q2WKS IV. Patient was hospitalized. Patient recovered.

Fabrazyme Side Effects Report #5613988-8
Fabrazyme side effect was reported by a Physician from UNITED STATES on Jan 22, 2008. Male patient, 50 years of age, weighting 120.6 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , finger amputation, pneumonia , sepsis . Fabrazyme dosage: 1 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with COZAAR, PRAVACHOL, MEDROL, RENAL CAPS, COMBIVENT, ADVAIR, COUMADIN, IMURAN. Patient died on 01/04/2008.

Fabrazyme Side Effects Report #4603878-1
Fabrazyme side effect was reported by a Health Professional from on Feb 22, 2005. Male patient, 50 years of age, weighting 154.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: blood creatine increased, blood urea increased, cardiac arrest , hernia , single vessel bypass graft. Fabrazyme dosage: 85 MG Q2WKS IV. Patient was hospitalized. Patient died on 02/12/2005.


Fabrazyme Side Effects Report #4610409-9
Fabrazyme side effect was reported by a Health Professional from on Mar 03, 2005. Male patient, 49 years of age, weighting 154.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , hernia repair. Fabrazyme dosage: 85 MG Q2WKS IV. Patient was hospitalized. Patient recovered.

Fabrazyme Side Effects Report #4622153-2
Fabrazyme side effect was reported by a Consumer or non-health professional from on Mar 16, 2005. Female patient, 48 years of age, weighting 138.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest . Fabrazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Fabrazyme Side Effects Report #4634776-5
Fabrazyme side effect was reported by a Health Professional from on Apr 07, 2005. Female patient, 48 years of age, weighting 138.0 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: asthenia, cardiac arrest , cardiac pacemaker insertion, syncope. Fabrazyme dosage: 70 MG Q2WKS IV. During the same period patient was treated with LISINOPRIL, LEXAPRO, KLONIPIN. Patient was hospitalized. Patient recovered.

Fabrazyme Side Effects Report #5452109-1
Fabrazyme side effect was reported by a Health Professional from UNITED STATES on Aug 31, 2007. Male patient, 46 years of age, weighting 154.3 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: blood creatinine increased, cardiac arrest , cerebral disorder, collapse of lung, convulsion, electroencephalogram abnormal, hyperkalaemia, pneumonia . Fabrazyme dosage: 35 MG QWK IV. Patient was hospitalized. Patient died.

Fabrazyme Side Effects Report #4728638-2
Fabrazyme side effect was reported by a Health Professional from UNITED STATES on July 14, 2005. Female patient, 46 years of age, weighting 194.2 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest . Fabrazyme dosage: 1 MG/KG Q2WKS; IV. During the same period patient was treated with ALTACE, TOPROL, PAXIL. Patient was hospitalized. Patient recovered.


Fabrazyme Side Effects Report #4741409-6
Fabrazyme side effect was reported by a Physician from UNITED STATES on July 26, 2005. Female patient, 46 years of age, weighting 194.2 lb, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , cardiac procedure complication, supraventricular tachycardia. Fabrazyme dosage: 1 MG/KG Q2WKS IV. During the same period patient was treated with ALTACE, TOPROL, PAXIL, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Fabrazyme Side Effects Report #4599967-0
Fabrazyme side effect was reported by a Physician from on Feb 18, 2005. Male patient, 39 years of age, was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: anoxic encephalopathy, cardiac arrest , cardiomegaly, circulatory collapse, coma, impaired gastric emptying, nausea , ventricular fibrillation. Fabrazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Fabrazyme Side Effects Report #5377932-3
Fabrazyme side effect was reported by a Health Professional from UNITED STATES on June 21, 2007. Male patient was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , cardiac disorder. Fabrazyme dosage: 70 MG Q2WKS IV. Patient died on 06/20/2007.

Fabrazyme Side Effects Report #5652184-5
Fabrazyme side effect was reported by a Physician from GERMANY on Feb 18, 2008. Male patient was diagnosed with fabry's disease and was treated with Fabrazyme. After drug was administered, patient experienced the following side effects: arterial occlusive disease, cardiac arrest , gangrene, sepsis . Fabrazyme dosage: unknown. Patient died on 12/08/2007.