Elspar and brain oedema Patient Reports February 12, 2012

Elspar Side Effects Report #4617097-6
Elspar side effect was reported by a Health Professional from on Jan 14, 2005. Female patient, child 6 years of age, was diagnosed with t-cell lymphoma and was treated with Elspar. After drug was administered, patient experienced the following side effects: brain oedema, coma, thrombosis. Elspar dosage: unknown. During the same period patient was treated with PREDNISONE, VINCRISTINE SULPHATE, DAUNORUBICIN, METHOTREXATE. Patient recovered.

Elspar Side Effects Report #4617094-0
Elspar side effect was reported by a Health Professional from on Jan 14, 2005. Female patient, child 10 years of age, was diagnosed with t-cell lymphoma and was treated with Elspar. After drug was administered, patient experienced the following side effects: brain oedema, cerebral haemorrhage. Elspar dosage: unknown. During the same period patient was treated with PREDNISONE, VINCRISTINE SULPHATE, DAUNORUBICIN, METHOTREXATE. Patient recovered.

Elspar Side Effects Report #4617096-4
Elspar side effect was reported by a Health Professional from on Jan 14, 2005. Female patient, child 9 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: brain oedema, thrombosis. Elspar dosage: unknown. During the same period patient was treated with DAUNORUBICIN, METHOTREXATE, PREDNISONE, VINCRISTINE SULPHATE. Patient recovered.

Elspar Side Effects Report #4586979-6
Elspar side effect was reported by a Physician from on Feb 10, 2005. Male patient, 45 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time abnormal, antithrombin iii decreased, blood fibrinogen decreased, brain oedema, haemorrhage intracranial, protein c decreased, protein s decreased, prothrombin level increased, superior sagittal sinus thrombosis. Elspar dosage: unknown. During the same period patient was treated with DAUNORUBICIN, VINCRISTINE SULPHATE, PREDNISONE, METHOTREXATE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.


Elspar Side Effects Report #4565965-6
Elspar side effect was reported by a Physician from on Jan 14, 2005. Female patient, 44 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: antithrombin iii decreased, blood fibrinogen decreased, brain oedema, cerebral haemorrhage, cerebrovascular accident. Elspar dosage: unknown. During the same period patient was treated with DOXORUBICIN, VINCRISTINE SULPHATE, PREDNISONE. Patient recovered.

Elspar Side Effects Report #5328392-X
Elspar side effect was reported by a Consumer or non-health professional from JAPAN on May 01, 2007. Male patient, 25 years of age, weighting 150.6 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: altered state of consciousness, blood bilirubin increased, brain oedema, cerebral haemorrhage, convulsion, hemiplegia, superior sagittal sinus thrombosis. Elspar dosage: unknown. During the same period patient was treated with ADRIAMYCIN PFS, VINCRISTINE, CYCLOPHOSPHAMIDE, MITOXANTRONE, PREDNISOLONE, CYTARABINE, METHOTREXATE. Patient was hospitalized. Patient recovered.

Elspar Side Effects Report #4561826-7
Elspar side effect was reported by a Physician from on Jan 14, 2005. Female patient, 44 years of age, was treated with Elspar. After drug was administered, patient experienced the following side effects: antithrombin iii decreased, blood fibrinogen decreased, brain oedema, cerebral haemorrhage, cerebrovascular accident. Elspar dosage: unknown. During the same period patient was treated with DOXORUBICIN, VINCRISTINE SULPHATE, PREDNISONE. Patient recovered.