Elspar and blood fibrinogen decreased Patient Reports February 12, 2012

Elspar Side Effects Report #4589382-8
Elspar side effect was reported by a Consumer or non-health professional from on Jan 25, 2005. Male patient, 59 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: antithrombin iii decreased, blood fibrinogen decreased, bone marrow depression, gastrointestinal haemorrhage. Elspar dosage: unknown. During the same period patient was treated with ADRIAMYCIN PFS, DEXAMETHASONE, VINCRISTINE SULPHATE. Patient died.

Elspar Side Effects Report #4559757-1
Elspar side effect was reported by a Health Professional from on Jan 14, 2005. Female patient, 48 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, blood fibrinogen decreased, cerebral infarction, prothrombin time prolonged, superior sagittal sinus thrombosis. Elspar dosage: unknown. Patient died.

Elspar Side Effects Report #4778500-4
Elspar side effect was reported by a Health Professional from JAPAN on Jan 14, 2005. Female patient, 48 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, blood fibrinogen decreased, cerebral infarction, prothrombin time prolonged, superior sagittal sinus thrombosis. Elspar dosage: unknown. Patient died.

Elspar Side Effects Report #4826516-1
Elspar side effect was reported by a Health Professional from JAPAN on Jan 14, 2005. Female patient, 48 years of age, weighting 116.8 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, blood fibrinogen decreased, cerebral infarction, clonic convulsion, coagulation factor ix level decreased, depressed level of consciousness, eyelid oedema, face oedema. Elspar dosage: unknown. During the same period patient was treated with PIRARUBICIN, VINDESINE, CYCLOPHOSPHAMIDE, PREDNISOLONE. Patient died on 12/05/1990.


Elspar Side Effects Report #4586979-6
Elspar side effect was reported by a Physician from on Feb 10, 2005. Male patient, 45 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time abnormal, antithrombin iii decreased, blood fibrinogen decreased, brain oedema, haemorrhage intracranial, protein c decreased, protein s decreased, prothrombin level increased, superior sagittal sinus thrombosis. Elspar dosage: unknown. During the same period patient was treated with DAUNORUBICIN, VINCRISTINE SULPHATE, PREDNISONE, METHOTREXATE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.

Elspar Side Effects Report #4565965-6
Elspar side effect was reported by a Physician from on Jan 14, 2005. Female patient, 44 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: antithrombin iii decreased, blood fibrinogen decreased, brain oedema, cerebral haemorrhage, cerebrovascular accident. Elspar dosage: unknown. During the same period patient was treated with DOXORUBICIN, VINCRISTINE SULPHATE, PREDNISONE. Patient recovered.

Elspar Side Effects Report #4589373-7
Elspar side effect was reported by a Physician from on Jan 25, 2005. Female patient, 30 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: antithrombin iii deficiency, blood fibrinogen decreased, sepsis . Elspar dosage: unknown. During the same period patient was treated with ADRIAMYCIN PFS, DEXAMETHASONE, VINCRISTINE SULPHATE. Patient died.

Elspar Side Effects Report #4586218-6
Elspar side effect was reported by a Consumer or non-health professional from on Jan 13, 2005. Female patient, 28 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: abnormal clotting factor, activated partial thromboplastin time abnormal, amnesia, antithrombin iii decreased, blood fibrinogen decreased, cerebral infarction, fibrin d dimer increased, fibrin increased. Elspar dosage: unknown. During the same period patient was treated with DAUNORUBICIN, VINCRISTINE SULPHATE, PREDNISONE, METHOTREXATE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.

Elspar Side Effects Report #4561835-8
Elspar side effect was reported by a Physician from on Jan 14, 2005. Female patient, 18 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: blood fibrinogen decreased, cerebrovascular accident, leukaemia recurrent, plasminogen decreased, subclavian vein thrombosis. Elspar dosage: unknown. During the same period patient was treated with DAUNORUBICIN, VINCRISTINE SULPHATE, PREDNISONE, METHOTREXATE. Patient recovered.


Elspar Side Effects Report #4564794-7
Elspar side effect was reported by a Physician from on Jan 14, 2005. Female patient, 18 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: blood fibrinogen decreased, cerebral infarction, cerebrovascular accident, leukaemia recurrent, plasminogen decreased, subclavian vein thrombosis, vascular occlusion. Elspar dosage: unknown. During the same period patient was treated with DAUNORUBICIN, VINCRISTINE SULPHATE, PREDNISONE, METHOTREXATE. Patient recovered.

Elspar Side Effects Report #4589368-3
Elspar side effect was reported by a Physician from on Jan 25, 2005. Female patient, 18 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: antithrombin iii deficiency, blood fibrinogen decreased, sepsis . Elspar dosage: unknown. During the same period patient was treated with ADRIAMYCIN PFS, DEXAMETHASONE, VINCRISTINE SULPHATE. Patient died.

Elspar Side Effects Report #4699846-4
Elspar side effect was reported by a Health Professional from on June 16, 2005. Female patient, 17 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood bilirubin increased, blood cholinesterase decreased, blood fibrinogen decreased, gamma-glutamyltransferase increased, hepatic function abnormal. Elspar dosage: unknown. During the same period patient was treated with DAUNORUBICIN, VINCRISTINE SULPHATE, VINCRISTINE SULPHATE, CYCLOPHOSPHAMIDE, PREDNISOLONE. Patient recovered.

Elspar Side Effects Report #4562557-X
Elspar side effect was reported by a Health Professional from on Jan 14, 2005. Female patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: antithrombin iii decreased, blood fibrinogen decreased, cerebral thrombosis, coagulopathy, plasminogen decreased. Elspar dosage: unknown. Patient was hospitalized. Patient recovered.

Elspar Side Effects Report #4583204-7
Elspar side effect was reported by a Health Professional from on Jan 14, 2005. Female patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: antithrombin iii decreased, blood fibrinogen decreased, cerebral thrombosis, coagulopathy, plasminogen decreased. Elspar dosage: unknown. Patient was hospitalized. Patient recovered.


Elspar Side Effects Report #4647538-X
Elspar side effect was reported by a Health Professional from on Jan 14, 2005. Female patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Elspar. After drug was administered, patient experienced the following side effects: antithrombin iii decreased, back pain , blood fibrinogen decreased, cerebral artery embolism, hyperglycaemia, plasminogen decreased. Elspar dosage: unknown. During the same period patient was treated with VINDESINE, ACLARUBICIN, CYCLOPHOSPHAMIDE, PREDNISOLONE, DAUNORUBICIN, VINCRISTINE SULPHATE. Patient was hospitalized. Patient recovered.

Elspar Side Effects Report #4561826-7
Elspar side effect was reported by a Physician from on Jan 14, 2005. Female patient, 44 years of age, was treated with Elspar. After drug was administered, patient experienced the following side effects: antithrombin iii decreased, blood fibrinogen decreased, brain oedema, cerebral haemorrhage, cerebrovascular accident. Elspar dosage: unknown. During the same period patient was treated with DOXORUBICIN, VINCRISTINE SULPHATE, PREDNISONE. Patient recovered.