Elaprase and flushing Patient Reports February 13, 2012

Elaprase Side Effects Report #5875750-0
Elaprase side effect was reported by a Health Professional from UNITED KINGDOM on Aug 22, 2008. Male patient, child 7 years of age, was diagnosed with mucopolysaccharidosis ii and was treated with Elaprase. After drug was administered, patient experienced the following side effects: feeling hot, flushing, infusion related reaction, pallor, petit mal epilepsy, tachypnoea. Elaprase dosage: 0.5 MG/KG, IV DRIP. During the same period patient was treated with HYDROCORTISONE, ALIMEMAZINE, HYDROXYZINE, ACETAMINOPHEN, RISPERDAL, CHLORPHENIRAMINE MALEATE, SALBUTAMOL, AMOXICILLIN. Patient recovered.

Elaprase Side Effects Report #6068844-0
Elaprase side effect was reported by a Health Professional from UNITED KINGDOM on Jan 20, 2009. Male patient, child 7 years of age, was diagnosed with mucopolysaccharidosis ii and was treated with Elaprase. After drug was administered, patient experienced the following side effects: feeling hot, flushing, infusion related reaction, pallor, petit mal epilepsy, tachypnoea. Elaprase dosage: 0.5 MG/KG, IV DRIP. During the same period patient was treated with HYDROCORTISONE, ALIMEMAZINE, HYDROXYZINE, PARACETAMOL, RISPERIDONE, CHLORPHENIRAMINE MALEATE, SALBUTAMOL, AMOXICILLIN. Patient recovered.

Elaprase Side Effects Report #5527685-0
Elaprase side effect was reported by a Physician from FRANCE on Nov 08, 2007. Male patient, child 12 years of age, weighting 66.14 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Elaprase. After drug was administered, patient experienced the following side effects: flushing, nausea , toxic epidermal necrolysis. Elaprase dosage: 18 MG, 1X/WEEK, IV DRIP. Patient recovered.

Elaprase Side Effects Report #5614158-X
Elaprase side effect was reported by a Physician from FRANCE on Jan 22, 2008. Male patient, child 12 years of age, weighting 66.14 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Elaprase. After drug was administered, patient experienced the following side effects: dermatitis bullous, flushing, nausea . Elaprase dosage: 18 MG, 1X/WEEK, IV DRIP. During the same period patient was treated with MOTILIUM. Patient recovered.