Doxorubicin and hepatic failure Patient Reports February 11, 2012

Doxorubicin Side Effects Report #4713605-5
Doxorubicin side effect was reported by a Physician from FRANCE on June 28, 2005. Female patient, 34 years of age, weighting 114.6 lb, was diagnosed with synovial sarcoma, ill-defined disorder, anaemia and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: anaemia, ascites, brain oedema, budd-chiari syndrome, cytolytic hepatitis, diarrhoea haemorrhagic, hepatic encephalopathy, hepatic failure, hepatorenal syndrome. Doxorubicin dosage: 20 MG/M2 (1 IN 1 D), INTRAVENOUS. During the same period patient was treated with IFOSFAMIDE, MESNA, DEXAMETHASONE, DACARBAZINE, ONDANSETRON, CHLORPROMAZINE, DARBEPOETIN ALFA. Patient was hospitalized. Patient recovered.

Doxorubicin Side Effects Report #5920077-1
Doxorubicin side effect was reported by a Health Professional from UNITED KINGDOM on Oct 01, 2008. Female patient, 21 years of age, was diagnosed with primary mediastinal large b-cell lymphoma and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: coagulopathy, encephalopathy, haemorrhage, hepatic failure, hepatitis b , lung injury, renal failure, sepsis . Doxorubicin dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISOLONE, RITUXIMAB, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #5937942-1
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 24, 2008. Female patient, 21 years of age, was diagnosed with primary mediastinal large b-cell lymphoma and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: encephalopathy, haemorrhage, hepatic failure, hepatitis b , lung injury, renal failure, sepsis . Doxorubicin dosage: unknown. During the same period patient was treated with PREDNISOLONE, CYCLOPHOSPHAMIDE, VINCRISTINE, RITUXIMAB. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #5949022-X
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 03, 2008. Female patient, 21 years of age, was diagnosed with primary mediastinal large b-cell lymphoma and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: encephalopathy, haemorrhage, hepatic failure, hepatitis b , lung injury, renal failure, sepsis . Doxorubicin dosage: unknown. During the same period patient was treated with PREDNISOLONE, CYCLOPHOSPHAMIDE, VINCRISTINE, RITUXIMAB. Patient was hospitalized. Patient died.


Doxorubicin Side Effects Report #5958522-8
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 11, 2008. Female patient, 21 years of age, was diagnosed with primary mediastinal large b-cell lymphoma and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: encephalopathy, haemorrhage, hepatic failure, hepatitis b , lung injury, renal failure, sepsis . Doxorubicin dosage: unknown. During the same period patient was treated with PREDNISOLONE, CYCLOPHOSPHAMIDE, VINCRISTINE, RITUXIMAB. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #5514158-4
Doxorubicin side effect was reported by a Physician from NORWAY on Nov 05, 2007. Female patient, 67 years of age, was diagnosed with ovarian cancer and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: colitis ischaemic, constipation , hepatic failure, hepatic ischaemia, renal ischaemia, urinary tract infection . Doxorubicin dosage: unknown. During the same period patient was treated with CORTISONE ACETATE, LAKTULOSE, AFIPRAN. Patient was hospitalized. Patient recovered.

Doxorubicin Side Effects Report #5677271-7
Doxorubicin side effect was reported by a Consumer or non-health professional from FRANCE on Mar 12, 2008. Female patient, 77 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: disease progression, hepatic encephalopathy, hepatic failure, hepatitis b virus. Doxorubicin dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISONE, CYCLOPHOSPHAMIDE, RITUXIMAB, VALACYCLOVIR, BACTRIM. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #4958157-X
Doxorubicin side effect was reported by a Physician from JAPAN on Mar 13, 2006. Male patient, 67 years of age, was diagnosed with multiple myeloma  and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, hepatic failure, hyperammonaemia, neutropenic infection, pneumonia , respiratory failure. Doxorubicin dosage: 12 MG , INTRAVENOUS. During the same period patient was treated with ONCOVIN, SULFAMETHOXAZOLE, DECADRON, DIFLUCAN. Patient died on 12/13/2005.

Doxorubicin Side Effects Report #5490613-0
Doxorubicin side effect was reported by a Health Professional from UNITED KINGDOM on Oct 15, 2007. Male patient, 33 years of age, was diagnosed with hepatic neoplasm malignant and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: encephalopathy, haemodialysis, hepatic failure, renal failure acute, tumour lysis syndrome. Doxorubicin dosage: unknown. Patient was hospitalized. Patient died.


Doxorubicin Side Effects Report #5523685-5
Doxorubicin side effect was reported by a Health Professional from UNITED KINGDOM on Nov 12, 2007. Male patient, 33 years of age, was diagnosed with hepatic neoplasm malignant and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: encephalopathy, hepatic failure, renal failure, tumour lysis syndrome. Doxorubicin dosage: unknown. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #5551726-8
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 30, 2007. Male patient, 33 years of age, was diagnosed with hepatic neoplasm malignant and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: encephalopathy, hepatic failure, renal failure acute, tumour lysis syndrome. Doxorubicin dosage: unknown. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #5572102-8
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 13, 2007. Male patient, 33 years of age, was diagnosed with hepatic neoplasm malignant and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: encephalopathy, hepatic failure, renal failure acute, tumour lysis syndrome. Doxorubicin dosage: unknown. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #5575153-2
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 18, 2007. Male patient, 33 years of age, was diagnosed with hepatic neoplasm malignant and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: encephalopathy, hepatic failure, renal failure acute, tumour lysis syndrome. Doxorubicin dosage: unknown. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #5600765-7
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Jan 14, 2008. Male patient, 33 years of age, was diagnosed with hepatic neoplasm malignant and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: encephalopathy, hepatic failure, renal failure acute, tumour lysis syndrome. Doxorubicin dosage: unknown. Patient was hospitalized. Patient died.


Doxorubicin Side Effects Report #5835969-1
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 25, 2008. Male patient, 33 years of age, was diagnosed with hepatic neoplasm malignant and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: encephalopathy, haemodialysis, hepatic failure, renal failure acute, tumour lysis syndrome. Doxorubicin dosage: unknown. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #4773151-X
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 15, 2005. Female patient, weighting 134.7 lb, was diagnosed with breast cancer  and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: febrile neutropenia, hepatic failure, hepatitis b , hepatitis fulminant. Doxorubicin dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, FILGRASTIM, BACTRIM DS, PACLITAXEL. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #4773153-3
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 15, 2005. Female patient, weighting 134.7 lb, was diagnosed with breast cancer  and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: febrile neutropenia, hepatic failure, hepatitis b . Doxorubicin dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, FILGRASTIM, BACTRIM DS, PACLITAXEL. Patient was hospitalized. Patient died.

Doxorubicin Side Effects Report #5678438-4
Doxorubicin side effect was reported by a Health Professional from FRANCE on Mar 05, 2008. Female patient, 77 years of age, was diagnosed with b-cell lymphoma and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: dialysis , hepatic encephalopathy, hepatic failure, hepatitis b , no therapeutic response. Doxorubicin dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISONE, CYCLOPHOSPHAMIDE, RITUXAN, VALACYCLOVIR, BACTRIM. Patient died on 07/01/2005.

Doxorubicin Side Effects Report #5698362-0
Doxorubicin side effect was reported by a Health Professional from FRANCE on Mar 26, 2008. Female patient, 77 years of age, was diagnosed with b-cell lymphoma and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: convulsion, dialysis , hepatic encephalopathy, hepatic failure, hepatitis b , oral herpes, urinary tract infection . Doxorubicin dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISONE, CYCLOPHOSPHAMIDE, RITUXAN, VALACYCLOVIR, BACTRIM. Patient died on 07/01/2005.


Doxorubicin Side Effects Report #4933985-5
Doxorubicin side effect was reported by a Physician from FRANCE on Feb 17, 2006. Male patient, 32 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, hepatic failure, hypertriglyceridaemia, pancytopenia, venoocclusive liver disease. Doxorubicin dosage: unknown. During the same period patient was treated with CYTARABINE, ELSPAR, ETOPOSIDE, ELDISINE, DEXAMETHASONE, LANVIS, BAACTRIM. Patient was hospitalized. Patient recovered.

Doxorubicin Side Effects Report #4968642-2
Doxorubicin side effect was reported by a Physician from FRANCE on Mar 20, 2006. Male patient, 32 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: ascites, blood triglycerides increased, coagulation factor v level decreased, coagulation factor vii level decreased, coagulopathy, dialysis , disseminated intravascular coagulation, hepatic failure, histiocytosis haematophagic. Doxorubicin dosage: (25 MG/M*2, DAY1, DAY8 + DAY15), INTRAVENOUS. During the same period patient was treated with ETOPOSIDE, CYTARABINE, ELSPAR, DEXAMETHASONE, ELDISINE, LANVIS, BACTRIM, THIOGUANINE. Patient was hospitalized. Patient recovered.

Doxorubicin Side Effects Report #5003819-1
Doxorubicin side effect was reported by a Physician from FRANCE on May 02, 2006. Male patient, 32 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: ascites, bleeding time prolonged, dialysis , disseminated intravascular coagulation, hepatic failure, histiocytosis haematophagic, hypertriglyceridaemia, pancytopenia, pleural effusion. Doxorubicin dosage: (25 MG/M*2, DAY1, DAY8 + DAY15), INTRAVENOUS. During the same period patient was treated with ETOPOSIDE, CYTARABINE, ELSPAR, DEXAMETHASONE, ELDISINE, LANVIS, BACTRIM. Patient was hospitalized. Patient recovered.

Doxorubicin Side Effects Report #4600078-6
Doxorubicin side effect was reported by a Consumer or non-health professional from on Feb 14, 2005. Male patient, 34 years of age, was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: condition aggravated, haematemesis, hepatic failure, hepatitis b , international normalised ratio increased, respiratory failure. Doxorubicin dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISONE, CYCLOPHOSPHAMIDE, RITUXIMAB, LAMIVUDINE, ADEFOVIR. Patient died.

Doxorubicin Side Effects Report #5506030-0
Doxorubicin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 17, 2007. Male patient, 33 years of age, was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: blood potassium increased, encephalopathy, haemodialysis, hepatic failure, hepatic necrosis, renal failure, tumour lysis syndrome. Doxorubicin dosage: unknown. Patient was hospitalized. Patient died.


Doxorubicin Side Effects Report #5691263-3
Doxorubicin side effect was reported by a Physician from GERMANY on Mar 28, 2008. Female patient was diagnosed with ovarian cancer and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: hepatic failure, muscular weakness, renal failure, sepsis . Doxorubicin dosage: unknown. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 06/23/2007.

Doxorubicin Side Effects Report #5743491-6
Doxorubicin side effect was reported by a Physician from GERMANY on May 09, 2008. Female patient was diagnosed with ovarian epithelial cancer and was treated with Doxorubicin. After drug was administered, patient experienced the following side effects: hepatic failure, muscular weakness, renal failure, sepsis . Doxorubicin dosage: unknown. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 06/23/2007.