Diprivan and propofol infusion syndrome Patient Reports February 12, 2012

Diprivan Side Effects Report #5735928-3
Diprivan side effect was reported by a Physician from UNITED STATES on Apr 29, 2008. Female patient, 26 years of age, weighting 119.0 lb, was diagnosed with status epilepticus and was treated with Diprivan. After drug was administered, patient experienced the following side effects: infection , propofol infusion syndrome. Diprivan dosage: 8 MG/KG, PER HOUR CONTINUOUS, INTRAVENOUS. Patient recovered.

Diprivan Side Effects Report #4831350-2
Diprivan side effect was reported by a Health Professional from JAPAN on Nov 09, 2005. Male patient, 40 years of age, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: hyperthermia malignant, polyneuropathy, propofol infusion syndrome, rhabdomyolysis. Diprivan dosage: unknown. Patient recovered.

Diprivan Side Effects Report #4869364-9
Diprivan side effect was reported by a Health Professional from JAPAN on Nov 09, 2005. Male patient, 40 years of age, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: hyperthermia malignant, propofol infusion syndrome, rhabdomyolysis. Diprivan dosage: unknown. Patient recovered.

Diprivan Side Effects Report #5542059-4
Diprivan side effect was reported by a Health Professional from GREECE on Nov 29, 2007. Male patient, 37 years of age, weighting 198.4 lb, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: atrioventricular block complete, bradycardia, propofol infusion syndrome, renal failure acute, respiratory failure, rhabdomyolysis. Diprivan dosage: 2,5-4,75 MG/KG/HR. During the same period patient was treated with DORMICUM, LEVOPHED, ULTIVA, DEPAKENE, TAZOCIN, MANNITOL. Patient recovered.


Diprivan Side Effects Report #5177339-8
Diprivan side effect was reported by a Health Professional from BELGIUM on May 11, 2006. Male patient, 30 years of age, weighting 116.8 lb, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: atrial fibrillation , blood creatine phosphokinase increased, blood lactic acid increased, electrocardiogram t wave inversion, propofol infusion syndrome, rhabdomyolysis, sinus arrhythmia, troponin t increased. Diprivan dosage: unknown. During the same period patient was treated with ULTIVA. Patient recovered.

Diprivan Side Effects Report #5200866-1
Diprivan side effect was reported by a Health Professional from BELGIUM on Dec 18, 2006. Male patient, 30 years of age, weighting 116.8 lb, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: atrial fibrillation , blood creatine phosphokinase increased, blood lactic acid increased, electrocardiogram t wave inversion, lung infection pseudomonal, propofol infusion syndrome, respiratory failure, rhabdomyolysis, sinus arrhythmia. Diprivan dosage: 5.7 MG/KG/HR,INTRAVENOUS. During the same period patient was treated with ULTIVA. Patient recovered.

Diprivan Side Effects Report #4831348-4
Diprivan side effect was reported by a Health Professional from JAPAN on Nov 09, 2005. Male patient, 30 years of age, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: hyperthermia malignant, myopathy, polyneuropathy, propofol infusion syndrome, rhabdomyolysis. Diprivan dosage: unknown. Patient recovered.

Diprivan Side Effects Report #4862843-X
Diprivan side effect was reported by a Pharmacist from UNITED STATES on Dec 16, 2005. Female patient, 30 years of age, was diagnosed with sedation, anaesthesia and was treated with Diprivan. After drug was administered, patient experienced the following side effects: arrhythmia , propofol infusion syndrome. Diprivan dosage: unknown. Patient died.

Diprivan Side Effects Report #5179218-9
Diprivan side effect was reported by a Consumer or non-health professional from LUXEMBOURG on Dec 14, 2006. Female patient, child 3 years of age, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: propofol infusion syndrome. Diprivan dosage: VARIABLE DOSE, HIGHEST 10ML/HOUR. Patient died on 07/01/2005.


Diprivan Side Effects Report #5200875-2
Diprivan side effect was reported by a Consumer or non-health professional from LUXEMBOURG on Dec 19, 2006. Female patient, child 3 years of age, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: propofol infusion syndrome. Diprivan dosage: VARIABLE DOSE, HIGHEST 10ML/HOUR, INTRAVENOUS. Patient died.

Diprivan Side Effects Report #5796802-X
Diprivan side effect was reported by a Consumer or non-health professional from LUXEMBOURG on Jan 22, 2007. Female patient, child 3 years of age, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: overdose, propofol infusion syndrome. Diprivan dosage: VARIABLE DOSE, HIGHEST 10ML/HOUR. Patient died on 07/01/2005.

Diprivan Side Effects Report #6037705-5
Diprivan side effect was reported by a Health Professional from UNITED STATES on Jan 11, 2009. Female patient, 29 years of age, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, circulatory collapse, haemodynamic instability, hypotension, metabolic acidosis, myoglobinuria, neurological decompensation, propofol infusion syndrome. Diprivan dosage: unknown. During the same period patient was treated with MANNITOL, NEUROMUSCULAR BLOCKADES, EPINEPHRINE, THIOPENTAL, PHENYLEPHRINE. Patient died.

Diprivan Side Effects Report #5565076-7
Diprivan side effect was reported by a Physician from FRANCE on Dec 05, 2007. Male patient, 20 years of age, was diagnosed with sedation, lung infection and was treated with Diprivan. After drug was administered, patient experienced the following side effects: propofol infusion syndrome. Diprivan dosage: unknown. During the same period patient was treated with ULTIVA, AUGMENTIN. Patient died on 05/05/2007.

Diprivan Side Effects Report #4844616-7
Diprivan side effect was reported by a Pharmacist from UNITED STATES on Nov 30, 2005. Female patient, 18 years of age, weighting 125.7 lb, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: acidosis, arrhythmia , depressed level of consciousness, hypotension, propofol infusion syndrome, renal failure acute, rhabdomyolysis. Diprivan dosage: 100-250 MG/ML CONTINUOUS IV. Patient died on 11/22/2005.


Diprivan Side Effects Report #5565081-0
Diprivan side effect was reported by a Physician from FRANCE on Dec 05, 2007. Male patient, 15 years of age, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: overdose, propofol infusion syndrome. Diprivan dosage: unknown. Patient died on 09/08/2007.

Diprivan Side Effects Report #5793247-3
Diprivan side effect was reported by a Physician from AUSTRIA on June 25, 2008. Female patient was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: hip arthroplasty, knee arthroplasty, necrosis, overdose, propofol infusion syndrome, rhabdomyolysis. Diprivan dosage: 4 MG TO 6 MG/KG/H. During the same period patient was treated with BRIETAL, ULTIVA, SUFENTA, CORTISONE. Patient was hospitalized. Patient recovered.

Diprivan Side Effects Report #4918672-1
Diprivan side effect was reported by a Health Professional from DENMARK on Dec 16, 2002. Female patient, weighting 154.3 lb, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: chromaturia, propofol infusion syndrome, ventricular tachycardia. Diprivan dosage: 60 HOURS WITH 20-35 ML PER HOUR. During the same period patient was treated with PROPOFOL, DICLOCIL, PENICILLIN, POTASSIUM CHLORIDE, KLEXANE, DIURAL, HALDID, NORADRENALIN. Patient was hospitalized and became disabled. Patient died on 11/17/2002.

Diprivan Side Effects Report #4860791-2
Diprivan side effect was reported by a Pharmacist from UNITED STATES on Dec 16, 2005. Male patient, 36 years of age, weighting 165.3 lb, was diagnosed with reduction of increased intracranial pressure, sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: acidosis, haemodialysis, propofol infusion syndrome, renal failure acute. Diprivan dosage: 100-300 MG/HR CONTINUOUS IV DRIP. Patient died on 08/30/2005.

Diprivan Side Effects Report #4860792-4
Diprivan side effect was reported by a Pharmacist from UNITED STATES on Dec 16, 2005. Male patient, 27 years of age, weighting 198.4 lb, was diagnosed with reduction of increased intracranial pressure, sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: propofol infusion syndrome, renal failure acute, rhabdomyolysis. Diprivan dosage: 100-350 MG/HR CONTINUOUS IV DRIP. Patient was hospitalized. Patient recovered.


Diprivan Side Effects Report #5797082-1
Diprivan side effect was reported by a Consumer or non-health professional from UNITED STATES on June 30, 2008. Male patient, 26 years of age, was diagnosed with intracranial pressure increased and was treated with Diprivan. After drug was administered, patient experienced the following side effects: cardiac disorder, propofol infusion syndrome, renal failure. Diprivan dosage: unknown. Patient died on 01/01/2005.

Diprivan Side Effects Report #4862853-2
Diprivan side effect was reported by a Pharmacist from UNITED STATES on Dec 16, 2005. Female patient, 18 years of age, was diagnosed with intracranial pressure increased and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, arrhythmia , aspartate aminotransferase increased, circulatory collapse, propofol infusion syndrome, rhabdomyolysis. Diprivan dosage: AVERAGE RATE OF 3.4 MG/KG/HR AND MAXIMUM RATE OF 5.4 MG/KG/HR FOR ONE HOUR. Patient died on 12/10/2005.

Diprivan Side Effects Report #5946936-1
Diprivan side effect was reported by a Physician from BELGIUM on Nov 05, 2008. Male patient, weighting 121.3 lb, was diagnosed with injury and was treated with Diprivan. After drug was administered, patient experienced the following side effects: overdose, propofol infusion syndrome. Diprivan dosage: unknown. During the same period patient was treated with LEVOPHED, DEPAKENE, AUGMENTIN, LYSOMUCIL, ZANTAC. Patient died on 09/10/2008.

Diprivan Side Effects Report #5975356-9
Diprivan side effect was reported by a Physician from BELGIUM on Nov 24, 2008. Male patient, weighting 121.3 lb, was diagnosed with injury and was treated with Diprivan. After drug was administered, patient experienced the following side effects: overdose, propofol infusion syndrome. Diprivan dosage: 3-4 MG/KG/H. During the same period patient was treated with LEVOPHED. Patient died on 09/10/2008.

Diprivan Side Effects Report #4595784-6
Diprivan side effect was reported by a Consumer or non-health professional from on Feb 16, 2005. Male patient, 28 years of age, was diagnosed with convulsion prophylaxis and was treated with Diprivan. After drug was administered, patient experienced the following side effects: propofol infusion syndrome. Diprivan dosage: unknown. During the same period patient was treated with PHENYTOIN. Patient died.


Diprivan Side Effects Report #5799164-7
Diprivan side effect was reported by a Health Professional from UNITED STATES on June 20, 2008. Male patient, 64 years of age, was diagnosed with convulsion and was treated with Diprivan. After drug was administered, patient experienced the following side effects: anoxic encephalopathy, blood triglycerides increased, hyperkalaemia, hypotension, lactic acidosis, metabolic acidosis, propofol infusion syndrome, renal failure acute, rhabdomyolysis. Diprivan dosage: 1 MG/KG, INTRAVENOUS BOLUS; 120 - 140 MGC/KG PER MINUTE, INTRAVENOUS. During the same period patient was treated with LORAZEPAM, PHENYTOIN, ZONISAMIDE, FOSPHENYTOIN. Patient died.

Diprivan Side Effects Report #5799162-3
Diprivan side effect was reported by a Consumer or non-health professional from UNITED STATES on June 26, 2008. Male patient, 26 years of age, was diagnosed with cerebral disorder and was treated with Diprivan. After drug was administered, patient experienced the following side effects: cardiac disorder, dialysis , propofol infusion syndrome, renal failure. Diprivan dosage: unknown. Patient died on 01/01/2005.

Diprivan Side Effects Report #5341353-X
Diprivan side effect was reported by a Health Professional from UNITED STATES on Apr 05, 2007. Female patient, child 3 years of age, was diagnosed with angiogram and was treated with Diprivan. After drug was administered, patient experienced the following side effects: cardiac failure, hypotension, metabolic acidosis, overdose, post procedural complication, propofol infusion syndrome, tachycardia. Diprivan dosage: 80 MG, 200 UG/KG/MIN. Patient recovered.

Diprivan Side Effects Report #5405697-5
Diprivan side effect was reported by a Health Professional from UNITED STATES on July 17, 2007. Female patient, child 3 years of age, was diagnosed with angiogram and was treated with Diprivan. After drug was administered, patient experienced the following side effects: cardiac failure, hypotension, metabolic acidosis, overdose, post procedural complication, propofol infusion syndrome, tachycardia. Diprivan dosage: 80 MG. Patient recovered.

Diprivan Side Effects Report #6037704-3
Diprivan side effect was reported by a Health Professional from UNITED STATES on Jan 11, 2009. Male patient, 18 years of age, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: anuria, arrhythmia , cardiac arrest , haemodynamic instability, intracranial pressure increased, metabolic acidosis, propofol infusion syndrome. Diprivan dosage: unknown. During the same period patient was treated with MORPHINE, VASPRESSORS. Patient died.


Diprivan Side Effects Report #5349256-1
Diprivan side effect was reported by a Pharmacist from FRANCE on May 29, 2007. Female patient, 17 years of age, was treated with Diprivan. After drug was administered, patient experienced the following side effects: cardiomyopathy , metabolic acidosis, off label use, propofol infusion syndrome, renal failure acute, rhabdomyolysis, shock. Diprivan dosage: unknown. During the same period patient was treated with MIDAZOLAM. Patient recovered.

Diprivan Side Effects Report #5405162-5
Diprivan side effect was reported by a Pharmacist from FRANCE on July 27, 2007. Female patient, 17 years of age, weighting 121.3 lb, was treated with Diprivan. After drug was administered, patient experienced the following side effects: cardiomyopathy , metabolic acidosis, off label use, propofol infusion syndrome, renal failure acute, rhabdomyolysis, shock. Diprivan dosage: unknown. During the same period patient was treated with MIDAZOLAM HYDROCHLORIDE, ACYCLOVIR. Patient recovered.

Diprivan Side Effects Report #5407096-9
Diprivan side effect was reported by a Pharmacist from FRANCE on July 27, 2007. Female patient, 17 years of age, weighting 121.3 lb, was treated with Diprivan. After drug was administered, patient experienced the following side effects: cardiomyopathy , metabolic acidosis, off label use, propofol infusion syndrome, renal failure acute, rhabdomyolysis, shock. Diprivan dosage: unknown. During the same period patient was treated with MIDAZOLAM, ACYCLOVIR. Patient recovered.

Diprivan Side Effects Report #5943612-6
Diprivan side effect was reported by a Physician from BELGIUM on Nov 03, 2008. Male patient, child 12 years of age, weighting 121.3 lb, was treated with Diprivan. After drug was administered, patient experienced the following side effects: overdose, propofol infusion syndrome. Diprivan dosage: unknown. Patient died.