Diprivan and aspartate aminotransferase increased Patient Reports February 12, 2012

Diprivan Side Effects Report #4649723-X
Diprivan side effect was reported by a Physician from on Apr 18, 2005. Male patient, 79 years of age, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, cardiac failure, disseminated intravascular coagulation, hepatic function abnormal, multi-organ failure, renal impairment, sepsis . Diprivan dosage: unknown. During the same period patient was treated with CIPROXAN, FIRSTCIN, VENOGLOBULIN, ELASPOL. Patient died on 02/17/2005.

Diprivan Side Effects Report #4817868-7
Diprivan side effect was reported by a Physician from JAPAN on Oct 26, 2005. Male patient, 27 years of age, weighting 110.2 lb, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, liver disorder. Diprivan dosage: unknown. During the same period patient was treated with NEOPHYLLIN, UNASYN, SEVOFRANE, DORMICUM, PROTERNOL. Patient recovered.

Diprivan Side Effects Report #4826073-X
Diprivan side effect was reported by a Physician from JAPAN on Oct 26, 2005. Male patient, 27 years of age, weighting 108.0 lb, was diagnosed with sedation, asthma , pneumonia  and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, blood pressure increased, brain oedema, liver disorder, mydriasis, subarachnoid haemorrhage. Diprivan dosage: unknown. During the same period patient was treated with NEOPHYLLIN, UNASYN, SEVOFRANE, DORMICUM, PROTERNOL, BOSMIN, MAGNESOL. Patient was hospitalized. Patient recovered.

Diprivan Side Effects Report #5169665-3
Diprivan side effect was reported by a Health Professional from JAPAN on Oct 18, 2006. Female patient, weighting 119.0 lb, was diagnosed with sedation, induction of anaesthesia, maintenance of anaesthesia, vomiting, sinus tachycardia and was treated with Diprivan. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase decreased, delayed recovery from anaesthesia, glasgow coma scale abnormal, hyperkalaemia, hyperthermia malignant, myoglobinuria, pyrexia. Diprivan dosage: unknown. During the same period patient was treated with PRIMPERAN, PENTAZOCINE LACTATE, HERBESSER. Patient was hospitalized. Patient recovered.


Diprivan Side Effects Report #4691034-0
Diprivan side effect was reported by a Physician from on June 02, 2005. Male patient, weighting 132.3 lb, was diagnosed with sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood amylase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, pancreatic disorder, rhabdomyolysis, swelling. Diprivan dosage: MEAN RATE OF INFUSION-15 ML/HOUR, MAXIMUM RATE OF 16 ML/HOUR. During the same period patient was treated with DORMICUM, CEFAMEZIN, XYLOCAINE, DOBUTREX, HEPARIN, SIGMART, INOVAN, GASTER. Patient was hospitalized. Patient recovered.

Diprivan Side Effects Report #4703188-8
Diprivan side effect was reported by a Physician from on June 02, 2005. Male patient, weighting 132.3 lb, was diagnosed with sedation, sepsis , ventricular tachycardia, shock, acute myocardial infarction, gastric ulcer and was treated with Diprivan. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood amylase increased, pancreatitis acute, rhabdomyolysis. Diprivan dosage: MEAN RATE OF INFUSION-15 ML/HOUR, MAXIMUM RATE OF 16 ML/HOUR. During the same period patient was treated with DORMICUM, CEFAMEZIN, XYLOCAINE, DOBUTREX, HEPARIN, SIGMART, INOVAN, GASTER. Patient was hospitalized. Patient recovered.

Diprivan Side Effects Report #5110223-4
Diprivan side effect was reported by a Physician from JAPAN on Apr 18, 2006. Female patient, 74 years of age, weighting 85.98 lb, was diagnosed with maintenance of anaesthesia, infection prophylaxis and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, hepatic function abnormal. Diprivan dosage: unknown. During the same period patient was treated with ISEPACIN, PANALDINE, ASPIRIN, ALEVIATIN, LAUGHING GAS. Patient recovered.

Diprivan Side Effects Report #4862853-2
Diprivan side effect was reported by a Pharmacist from UNITED STATES on Dec 16, 2005. Female patient, 18 years of age, was diagnosed with intracranial pressure increased and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, arrhythmia , aspartate aminotransferase increased, circulatory collapse, propofol infusion syndrome, rhabdomyolysis. Diprivan dosage: AVERAGE RATE OF 3.4 MG/KG/HR AND MAXIMUM RATE OF 5.4 MG/KG/HR FOR ONE HOUR. Patient died on 12/10/2005.

Diprivan Side Effects Report #5048552-5
Diprivan side effect was reported by a Physician from JAPAN on June 28, 2006. Female patient, 65 years of age, was diagnosed with induction of anaesthesia, maintenance of anaesthesia and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, liver function test abnormal, myoglobin urine present. Diprivan dosage: unknown. During the same period patient was treated with SEVOFLURANE. Patient was hospitalized. Patient recovered.


Diprivan Side Effects Report #5246165-3
Diprivan side effect was reported by a Consumer or non-health professional from JAPAN on Feb 05, 2007. Female patient, 14 years of age, weighting 119.0 lb, was diagnosed with induction of anaesthesia, maintenance of anaesthesia, sedation and was treated with Diprivan. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood creatine phosphokinase increased, blood creatine phosphokinase mb increased, blood lactate dehydrogenase increased, hyperkalaemia, myoglobinuria, pyrexia. Diprivan dosage: unknown. During the same period patient was treated with PRIMPERAN, SOSEGON, DILTIAZEM HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Diprivan Side Effects Report #5150614-9
Diprivan side effect was reported by a Physician from JAPAN on Nov 06, 2006. Male patient, 64 years of age, was diagnosed with induction and maintenance of anaesthesia and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal. Diprivan dosage: unknown. During the same period patient was treated with KETAMINE, ALTAT, RHYTHMY, FENTANYL CITRATE, MUSCULAX, MARCAINE, HALOSPOR, DECADRON. Patient recovered.

Diprivan Side Effects Report #5152348-3
Diprivan side effect was reported by a Physician from JAPAN on Nov 06, 2006. Male patient, 64 years of age, was diagnosed with induction and maintenance of anaesthesia and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal, post procedural nausea. Diprivan dosage: unknown. During the same period patient was treated with KETAMINE, ALTAT, RHYTHMY, FENTANYL, MUSCULAX, MARCAINE, HALOSPOR, DECADRON. Patient recovered.

Diprivan Side Effects Report #4873021-2
Diprivan side effect was reported by a Physician from JAPAN on Dec 28, 2005. Female patient, 64 years of age, was diagnosed with induction and maintenance of anaesthesia, infiltration anaesthesia and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal, platelet count decreased, renal impairment. Diprivan dosage: unknown. During the same period patient was treated with PENTCILLIN, XYLOCAINE, FENTANEST, MUSCULAX, KETALAR, PRIMPERAN, ROPION. Patient was hospitalized and became disabled. Patient recovered.

Diprivan Side Effects Report #4893792-9
Diprivan side effect was reported by a Physician from JAPAN on Dec 28, 2005. Female patient, 64 years of age, was diagnosed with induction and maintenance of anaesthesia, infection prophylaxis, infiltration anaesthesia, induction of anaesthesia, hypotonia, prophylaxis of nausea and vomiting, pain , fluid replacement and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, disseminated intravascular coagulation, haemodialysis, hepatic function abnormal, hypotension, liver disorder, operative haemorrhage. Diprivan dosage: unknown. During the same period patient was treated with PENTCILLIN, XYLOCAINE, FENTANEST, MUSCULAX, KETALAR, PRIMPERAN, ROPION. Patient was hospitalized and became disabled. Patient recovered.


Diprivan Side Effects Report #4896742-4
Diprivan side effect was reported by a Physician from JAPAN on Dec 28, 2005. Female patient, 64 years of age, was diagnosed with induction and maintenance of anaesthesia, infection prophylaxis, infiltration anaesthesia, induction of anaesthesia, hypotonia, prophylaxis of nausea and vomiting, pain , fluid replacement and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia postoperative, aspartate aminotransferase increased, disseminated intravascular coagulation, haemodialysis, liver disorder, nausea , oedema, operative haemorrhage. Diprivan dosage: unknown. During the same period patient was treated with PENTCILLIN, XYLOCAINE, FENTANEST, MUSCULAX, KETALAR, PRIMPERAN, ROPION. Patient was hospitalized and became disabled. Patient recovered.

Diprivan Side Effects Report #4920214-1
Diprivan side effect was reported by a Physician from JAPAN on Dec 28, 2005. Female patient, 64 years of age, weighting 134.9 lb, was diagnosed with induction and maintenance of anaesthesia, infection prophylaxis, infiltration anaesthesia, induction of anaesthesia, hypotonia, prophylaxis of nausea and vomiting, pain , fluid replacement and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, anaemia postoperative, aspartate aminotransferase increased, blood pressure decreased, disseminated intravascular coagulation, haemodialysis, liver disorder, nausea . Diprivan dosage: unknown. During the same period patient was treated with PENTCILLIN, XYLOCAINE, FENTANEST, MUSCULAX, KETALAR, PRIMPERAN, ROPION. Patient was hospitalized and became disabled. Patient recovered.

Diprivan Side Effects Report #4865171-1
Diprivan side effect was reported by a Health Professional from FRANCE on Dec 06, 2005. Female patient, 62 years of age, was diagnosed with anaesthesia and was treated with Diprivan. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hypertriglyceridaemia. Diprivan dosage: unknown. During the same period patient was treated with MIDAZOLAM, TRACRIUM, SUFENTA. Patient was hospitalized. Patient recovered.

Diprivan Side Effects Report #4862179-7
Diprivan side effect was reported by a Health Professional from FRANCE on Dec 15, 2005. Female patient, 34 years of age, was diagnosed with anaesthesia and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, transaminases increased. Diprivan dosage: unknown. During the same period patient was treated with ESMERON, SUFENTA, SEVORANE, DIANTALVIC, PERFALGAN. Patient was hospitalized. Patient recovered.

Diprivan Side Effects Report #4871714-4
Diprivan side effect was reported by a Health Professional from FRANCE on Dec 15, 2005. Female patient, 34 years of age, was diagnosed with anaesthesia and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, transaminases increased. Diprivan dosage: unknown. During the same period patient was treated with ESMERON, SUFENTA, SEVORANE, DIANTALVIC, PERFALGAN. Patient was hospitalized. Patient recovered.


Diprivan Side Effects Report #4752198-3
Diprivan side effect was reported by a Health Professional from FRANCE on Aug 16, 2005. Female patient, 21 years of age, was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic enzyme increased. Diprivan dosage: unknown. During the same period patient was treated with PERFALGAN, SPASFON, ALFENTANIL. Patient was hospitalized. Patient recovered.

Diprivan Side Effects Report #5194496-8
Diprivan side effect was reported by a Health Professional from JAPAN on Dec 11, 2006. Female patient, 14 years of age, weighting 119.0 lb, was diagnosed with bleeding time prolonged, blood pressure increased, brain oedema, cerebral vasoconstriction, hypotonia, induction of anaesthesia, infection prophylaxis and was treated with Diprivan. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood lactate dehydrogenase increased, body temperature decreased, delayed recovery from anaesthesia, depressed level of consciousness, hepatic trauma, hyperkalaemia, hypoperfusion, liver disorder. Diprivan dosage: unknown. Patient was hospitalized. Patient recovered.

Diprivan Side Effects Report #4976493-8
Diprivan side effect was reported by a Physician from JAPAN on Feb 02, 2006. Female patient was diagnosed with epidural anaesthesia, analgesic effect and was treated with Diprivan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, liver disorder. Diprivan dosage: TARGET BLOOD CONCENTRATION 0-5 UG/ML. During the same period patient was treated with XYLOCAINE, MARCAINE, MEROPEN, ALTAT, HORIZON, FENTANEST, DROLEPTAN. Patient was hospitalized. Patient recovered.