Depakene and ammonia increased Patient Reports February 12, 2012

Depakene Side Effects Report #4669945-1
Depakene side effect was reported by a Consumer or non-health professional from on May 13, 2005. Female patient, child 3 years of age, was diagnosed with myoclonic epilepsy, petit mal epilepsy and was treated with Depakene. After drug was administered, patient experienced the following side effects: ammonia decreased, ammonia increased, disseminated intravascular coagulation, hepatic failure, loss of consciousness, vomiting. Depakene dosage: unknown. Patient was hospitalized. Patient recovered.

Depakene Side Effects Report #4684904-0
Depakene side effect was reported by a Consumer or non-health professional from on May 13, 2005. Female patient, child 3 years of age, was diagnosed with myoclonic epilepsy, petit mal epilepsy and was treated with Depakene. After drug was administered, patient experienced the following side effects: ammonia decreased, ammonia increased, anorexia, asthenia, blood fibrinogen decreased, disseminated intravascular coagulation, hepatic failure, liver transplant , loss of consciousness. Depakene dosage: unknown. Patient was hospitalized. Patient recovered.

Depakene Side Effects Report #4553932-8
Depakene side effect was reported by a Consumer or non-health professional from on Jan 05, 2005. Female patient, 25 years of age, weighting 99.21 lb, was diagnosed with mania, schizophrenia and was treated with Depakene. After drug was administered, patient experienced the following side effects: ammonia increased, ascites, blood pressure decreased, bradycardia, coma, condition aggravated, dysphagia, hepatic function abnormal, hepatitis acute. Depakene dosage: unknown. During the same period patient was treated with BICAMOL, VEGETAMIN, RISPERIDONE, CARBAMAZEPINE, DIAZEPAM, SULPIRIDE, QUETIAPINE, CHLORPROMAZINE. Patient was hospitalized. Patient died on 11/02/2004.

Depakene Side Effects Report #4579687-9
Depakene side effect was reported by a Consumer or non-health professional from on Jan 05, 2005. Female patient, 25 years of age, weighting 99.21 lb, was diagnosed with mania, schizophrenia and was treated with Depakene. After drug was administered, patient experienced the following side effects: ammonia increased, ascites, bradycardia, condition aggravated, hepatic function abnormal, hepatitis acute, hypercapnia, hypoxia, jaundice . Depakene dosage: unknown. During the same period patient was treated with BICAMOL, VEGETAMIN, RISPERIDONE, CARBAMAZEPINE, DIAZEPAM, SULPIRIDE, QUETIAPINE, CHLORPROMAZINE. Patient was hospitalized. Patient died on 11/02/2004.


Depakene Side Effects Report #4874567-3
Depakene side effect was reported by a Consumer or non-health professional from FRANCE on Dec 30, 2005. Male patient, 82 years of age, was diagnosed with epilepsy , essential hypertension, psychotic disorder  and was treated with Depakene. After drug was administered, patient experienced the following side effects: ammonia increased, cognitive disorder, confusional state, difficulty in walking, eschar, extrapyramidal disorder, eyelid ptosis, weight decreased. Depakene dosage: unknown. During the same period patient was treated with FUROSEMIDE, MEMANTINE, IRBESARTAN, GINKGO TREE LEAVES, PARACETAMOL, LAMOTRIGINE. Patient was hospitalized. Patient recovered.

Depakene Side Effects Report #4894527-6
Depakene side effect was reported by a Consumer or non-health professional from FRANCE on Dec 30, 2005. Male patient, 82 years of age, was diagnosed with epilepsy , essential hypertension, psychotic disorder  and was treated with Depakene. After drug was administered, patient experienced the following side effects: ammonia increased, cerebral atrophy, cerebral haematoma, cognitive disorder, confusional state, difficulty in walking, disorientation, eschar, extrapyramidal disorder. Depakene dosage: unknown. During the same period patient was treated with FUROSEMIDE, MEMANTINE, IRBESARTAN, GINKGO TREE LEAVES, PARACETAMOL, LAMOTRIGINE. Patient was hospitalized. Patient recovered.

Depakene Side Effects Report #5139714-7
Depakene side effect was reported by a Health Professional from FRANCE on Oct 20, 2006. Female patient, 68 years of age, was diagnosed with epilepsy  and was treated with Depakene. After drug was administered, patient experienced the following side effects: abasia, activities of daily living impaired, ammonia increased, amnesia, anorexia, areflexia, cerebral atrophy, cognitive disorder, coordination abnormal. Depakene dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Depakene Side Effects Report #5174664-1
Depakene side effect was reported by a Health Professional from FRANCE on Oct 20, 2006. Female patient, 68 years of age, was diagnosed with epilepsy  and was treated with Depakene. After drug was administered, patient experienced the following side effects: abasia, activities of daily living impaired, ammonia increased, amnesia, anorexia, areflexia, cerebral atrophy, cognitive disorder, coordination abnormal. Depakene dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Depakene Side Effects Report #4631917-0
Depakene side effect was reported by a Consumer or non-health professional from on May 07, 2004. Female patient, 53 years of age, was diagnosed with epilepsy  and was treated with Depakene. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, ammonia increased, blood albumin decreased, blood pressure decreased, brain neoplasm, cerebral ventricle dilatation, cerebral ventriculogram abnormal, hepatitis fulminant. Depakene dosage: unknown. During the same period patient was treated with DEXAMETHASONE, FUROSEMIDE, HYDERGIN, PIRACETAM, DOPAMINE, DOBUTAMINE. Patient was hospitalized. Patient died on 12/26/2003.


Depakene Side Effects Report #4620422-3
Depakene side effect was reported by a Pharmacist from on Mar 21, 2005. Female patient, 43 years of age, was diagnosed with bipolar i disorder and was treated with Depakene. After drug was administered, patient experienced the following side effects: ammonia increased, bipolar i disorder, condition aggravated, confusional state, sedation. Depakene dosage: PO 1000 MG HS 500 MG AM; PO 750 NG HS 500 MG AM. During the same period patient was treated with SEROQUEL, ZYPREXA, COGENTIN, RISPERDAL, PROLIXIN, HALDOL. Patient was hospitalized. Patient recovered.

Depakene Side Effects Report #4622493-7
Depakene side effect was reported by a Pharmacist from on Mar 25, 2005. Female patient, 43 years of age, was diagnosed with bipolar i disorder and was treated with Depakene. After drug was administered, patient experienced the following side effects: abnormal behaviour, ammonia increased, confusional state, sedation. Depakene dosage: PO 1000 MG HS 500 MG AM, 750 MG HS 500 MG AM. During the same period patient was treated with SEROQUEL, ZYPREXA, COGENTIN, RISPERDAL, PROLIXIN. Patient was hospitalized. Patient recovered.

Depakene Side Effects Report #4620417-X
Depakene side effect was reported by a Pharmacist from on Mar 21, 2005. Male patient, 20 years of age, was diagnosed with bipolar disorder  and was treated with Depakene. After drug was administered, patient experienced the following side effects: aggression, agitation, alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased, laboratory test abnormal. Depakene dosage: 500 MG AM 1000 MG Q HS. During the same period patient was treated with ZYPREXA, HALDOL, ATIVIAN, THORAZINE. Patient recovered.

Depakene Side Effects Report #5718684-4
Depakene side effect was reported by a Physician from FRANCE on Apr 17, 2008. Male patient, 25 years of age, was treated with Depakene. After drug was administered, patient experienced the following side effects: ammonia increased, somnolence, toxic encephalopathy, tremor. Depakene dosage: 2400MG DAILY (LOW DOSE). Patient recovered.

Depakene Side Effects Report #4622492-5
Depakene side effect was reported by a Pharmacist from on Mar 25, 2005. Male patient, 20 years of age, was treated with Depakene. After drug was administered, patient experienced the following side effects: aggression, agitation, alanine aminotransferase increased, ammonia increased, aspartate aminotransferase increased. Depakene dosage: 500 MG AM 1000 MG HS. During the same period patient was treated with ZYPREXA, HALDOL, ATIVAN. Patient recovered.