Defibrotide and blood pressure decreased Patient Reports February 12, 2012

Defibrotide Side Effects Report #5176702-9
Defibrotide side effect was reported by a Physician from UNITED STATES on Dec 13, 2006. Male patient, weighting 220.5 lb, was diagnosed with venoocclusive disease and was treated with Defibrotide. After drug was administered, patient experienced the following side effects: acidosis, blood bilirubin increased, blood pressure decreased, cardiac enzymes increased, cardio-respiratory arrest, dilatation ventricular, haemoglobin decreased, haemothorax. Defibrotide dosage: 1000MG Q6HRS IV. During the same period patient was treated with ACETYLCYSTEINE, ACYCLOVIR, CASPOFUNGIN, FILGRASTIM, LEVOFLOXACIN, MEROPEREM, METHYLPREDNISOLONE, TACROLIMUS. Patient recovered.

Defibrotide Side Effects Report #4955795-5
Defibrotide side effect was reported by a Physician from UNITED STATES on Mar 27, 2006. Female patient, weighting 35.27 lb, was diagnosed with bone marrow transplant , venoocclusive liver disease and was treated with Defibrotide. After drug was administered, patient experienced the following side effects: blood pressure decreased, bradycardia, haematemesis, nausea , oxygen saturation decreased, respiratory disorder, resuscitation. Defibrotide dosage: 40MG/KG IV/Q6HRS Q6HRS IV. Patient recovered.