Decitabine and hypotension Patient Reports February 12, 2012

Decitabine Side Effects Report #5302025-0
Decitabine side effect was reported by a Physician from CANADA on Mar 29, 2007. Female patient, 77 years of age, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood lactic acid increased, clostridial infection, colitis ischaemic, hypotension, international normalised ratio decreased, large intestine perforation, necrotising colitis. Decitabine dosage: 20 MG/M**2; QD X5DQ28D; IV. During the same period patient was treated with DESFERAL, DIURETICS. Patient was hospitalized. Patient died on 07/04/2006.

Decitabine Side Effects Report #5449580-8
Decitabine side effect was reported by a Health Professional from ARGENTINA on Aug 28, 2007. Male patient, 68 years of age, weighting 176.4 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: febrile neutropenia, gastrointestinal haemorrhage, haematuria, haemoglobin decreased, hypotension, melaena, platelet count decreased, white blood cell count decreased. Decitabine dosage: 20 MG/M2, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5468289-8
Decitabine side effect was reported by a Health Professional from ARGENTINA on Sept 13, 2007. Male patient, 68 years of age, weighting 176.4 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: febrile neutropenia, gastroduodenitis, gastrointestinal haemorrhage, haematuria, haemoglobin decreased, hiatus hernia, hypotension, melaena, oesophagitis. Decitabine dosage: 20 MG/M2, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5485658-0
Decitabine side effect was reported by a Physician from ARGENTINA on Sept 17, 2007. Male patient, 68 years of age, weighting 118.2 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: ascites, disorientation, gastrointestinal haemorrhage, hypotension, neutropenia, thrombocytopenia. Decitabine dosage: 10 MG/M2, INTRAVENOUS. During the same period patient was treated with ALDOSTERONE. Patient was hospitalized. Patient recovered.


Decitabine Side Effects Report #5328352-9
Decitabine side effect was reported by a Physician from TURKEY on May 07, 2007. Female patient, 64 years of age, weighting 163.1 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, caecitis, diarrhoea, haemoglobin decreased, haemorrhage intracranial, hypotension, liver function test abnormal, neutropenia, prothrombin time prolonged. Decitabine dosage: 15 MG/M**2; Q8H; IV. During the same period patient was treated with DEFEROXAMINE MESYLATE. Patient was hospitalized. Patient died on 03/22/2007.

Decitabine Side Effects Report #5531272-8
Decitabine side effect was reported by a Physician from THAILAND on Nov 14, 2007. Female patient was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: abdominal pain , colitis, diarrhoea, hypotension, neutrophil count decreased, pyrexia, white blood cell count decreased. Decitabine dosage: 29 MG, INTRAVENOUS; 29 MG, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5646198-9
Decitabine side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Feb 18, 2008. Female patient was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: colitis, haematocrit decreased, hypotension, neutropenia, platelet count decreased, pyrexia, septic shock. Decitabine dosage: 29 MG, INTRAVENOUS. During the same period patient was treated with SODAMINT, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5442923-0
Decitabine side effect was reported by a Physician from CANADA on Aug 16, 2007. Female patient, 79 years of age, weighting 207.2 lb, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: atrial fibrillation , blood creatinine increased, candida pneumonia, cardiac failure congestive, cardiac valve vegetation, endocarditis , hypophosphataemia, hypotension, mucosal inflammation. Decitabine dosage: 20 MG/M2, INTRAVENOUS. Patient was hospitalized. Patient died on 12/22/2006.

Decitabine Side Effects Report #5739590-5
Decitabine side effect was reported by a Physician from TURKEY on May 02, 2008. Female patient, 64 years of age, weighting 163.1 lb, was treated with Decitabine. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, caecitis, haemoglobin decreased, haemorrhage intracranial, hepatic function abnormal, hypotension, loss of consciousness, multi-organ failure, neutropenia. Decitabine dosage: 225 MG, INTRAVENOUS. Patient was hospitalized and became disabled. Patient died on 03/22/2007.