Decitabine and febrile neutropenia Patient Reports February 12, 2012

Decitabine Side Effects Report #5670607-2
Decitabine side effect was reported by a Health Professional from UNITED STATES on Mar 04, 2008. Male patient, 68 years of age, weighting 160.9 lb, was diagnosed with myelofibrosis and was treated with Decitabine. After drug was administered, patient experienced the following side effects: cardiac failure congestive, catheter sepsis, febrile neutropenia, lung consolidation, nephrolithiasis, opportunistic infection, pneumonia fungal, pulmonary oedema, renal failure. Decitabine dosage: 0.3 MG/KG, 1 IN 1 DAY, SUBCUTANEOUS. Patient was hospitalized. Patient died on 03/05/2008.

Decitabine Side Effects Report #5444077-3
Decitabine side effect was reported by a Health Professional from UNITED STATES on Aug 20, 2007. Female patient, 67 years of age, weighting 196.0 lb, was diagnosed with myelofibrosis and was treated with Decitabine. After drug was administered, patient experienced the following side effects: acute febrile neutrophilic dermatosis, febrile neutropenia, pancytopenia. Decitabine dosage: 264 MG, IN 1 TOTAL, SUBCUTANEOUS. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5565836-2
Decitabine side effect was reported by a Physician from GERMANY on Dec 05, 2007. Male patient, 76 years of age, weighting 158.7 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: erysipelas, febrile neutropenia, granulocytopenia, mucosal inflammation, muscle spasticity, myositis , pneumonia , refusal of treatment by patient, respiratory failure. Decitabine dosage: 15 MG/M2, 1 IN 8 HOUR, INTRAVENOUS. Patient was hospitalized. Patient died on 10/12/2006.

Decitabine Side Effects Report #5730075-9
Decitabine side effect was reported by a Physician from GERMANY on Apr 23, 2008. Male patient, 76 years of age, weighting 158.7 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: dyspnoea, erysipelas, febrile neutropenia, haemoglobin decreased, mucosal inflammation, myositis , pneumonia , respiratory failure, white blood cell count decreased. Decitabine dosage: 15 MG/M2, 1 IN 8 HOUR, INTRAVENOUS. Patient was hospitalized. Patient died on 10/12/2006.


Decitabine Side Effects Report #5760257-1
Decitabine side effect was reported by a Physician from GERMANY on May 21, 2008. Male patient, 76 years of age, weighting 158.7 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: erysipelas, febrile neutropenia, mucosal inflammation, pneumonia , respiratory failure. Decitabine dosage: 15 MG/M2, 1 IN 8 HOUR, INTRAVENOUS. Patient was hospitalized. Patient died on 10/12/2006.

Decitabine Side Effects Report #5491283-8
Decitabine side effect was reported by a Physician from ISRAEL on Oct 08, 2007. Female patient, 73 years of age, weighting 136.7 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: abdominal pain upper, diarrhoea, disease progression, febrile neutropenia, lung infection, myelodysplastic syndrome, pneumonia , respiratory failure, sepsis . Decitabine dosage: INTRAVENOUS; 30 MG, INTRAVENOUS. Patient was hospitalized. Patient died on 09/25/2007.

Decitabine Side Effects Report #5449580-8
Decitabine side effect was reported by a Health Professional from ARGENTINA on Aug 28, 2007. Male patient, 68 years of age, weighting 176.4 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: febrile neutropenia, gastrointestinal haemorrhage, haematuria, haemoglobin decreased, hypotension, melaena, platelet count decreased, white blood cell count decreased. Decitabine dosage: 20 MG/M2, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5468289-8
Decitabine side effect was reported by a Health Professional from ARGENTINA on Sept 13, 2007. Male patient, 68 years of age, weighting 176.4 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: febrile neutropenia, gastroduodenitis, gastrointestinal haemorrhage, haematuria, haemoglobin decreased, hiatus hernia, hypotension, melaena, oesophagitis. Decitabine dosage: 20 MG/M2, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5732043-X
Decitabine side effect was reported by a Health Professional from VENEZUELA on Apr 26, 2008. Male patient, 56 years of age, weighting 200.6 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: febrile neutropenia, fungal sepsis, mucormycosis, pancytopenia, rectal abscess, skin lesion, skin necrosis, skin ulcer. Decitabine dosage: 15 MG/M2, INTRAVENOUS. During the same period patient was treated with AMIKACIN, UNASYN. Patient was hospitalized. Patient died on 04/14/2008.


Decitabine Side Effects Report #5567421-5
Decitabine side effect was reported by a Physician from NETHERLANDS on Dec 05, 2007. Female patient was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: febrile neutropenia, haemoglobin decreased, platelet count decreased, tooth abscess, tooth extraction, ulcer , white blood cell count decreased. Decitabine dosage: 15 MG/M2, 3 IN 1 DAY, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5729881-6
Decitabine side effect was reported by a Physician from UNITED STATES on Apr 21, 2008. Female patient was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: fatigue, febrile neutropenia, hepatic enzyme increased, hypokalaemia, pancytopenia, syncope. Decitabine dosage: 20 MG/M2, IN 1 DAY, INTRAVENOUS. Patient recovered.

Decitabine Side Effects Report #5730782-8
Decitabine side effect was reported by a Physician from UNITED STATES on Apr 21, 2008. Female patient was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: fatigue, febrile neutropenia, haematotoxicity, hepatic enzyme increased, hypokalaemia, pancytopenia, syncope. Decitabine dosage: 20 MG/M2, IN 1 DAY, INTRAVENOUS. Patient recovered.

Decitabine Side Effects Report #5730788-9
Decitabine side effect was reported by a Physician from UNITED STATES on Apr 21, 2008. Female patient was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: fatigue, febrile neutropenia, hepatic enzyme increased, hypokalaemia, pancytopenia, syncope. Decitabine dosage: 20 MG/M2, IN 1 DAY, INTRAVENOUS. Patient recovered.

Decitabine Side Effects Report #5835916-2
Decitabine side effect was reported by a Physician from COLOMBIA on July 21, 2008. Female patient, weighting 165.3 lb, was diagnosed with myelodysplastic syndrome and was treated with Decitabine. After drug was administered, patient experienced the following side effects: arthritis , bone marrow failure, deep vein thrombosis , febrile neutropenia, hepatitis , mucosal inflammation. Decitabine dosage: 120 MG/M2, INTRAVENOUS. Patient was hospitalized. Patient recovered.


Decitabine Side Effects Report #5748893-X
Decitabine side effect was reported by a Physician from COLOMBIA on May 16, 2008. Female patient, 56 years of age, was diagnosed with chronic myelomonocytic leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, febrile neutropenia, multi-organ failure, shock, urinary tract infection . Decitabine dosage: 37 MG, INTRAVENOUS. During the same period patient was treated with CAPTOPRIL, AMIODARONE, OMEPRAZOLE, PLATELET TRANSFUSION. Patient died on 04/03/2008.

Decitabine Side Effects Report #5930647-2
Decitabine side effect was reported by a Health Professional from UNITED STATES on Oct 10, 2008. Male patient, 84 years of age, weighting 160.9 lb, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: febrile neutropenia, hypoxia, pleural effusion, pulmonary embolism , ventricular dysfunction. Decitabine dosage: 20 MG/M2, 1 IN 1 DAY, INTRAVENOUS; 20 MG/M2, 1 IN 1 DAY, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5256975-4
Decitabine side effect was reported by a Pharmacist from UNITED STATES on Mar 05, 2007. Male patient, 78 years of age, weighting 225.0 lb, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: febrile neutropenia, interstitial lung disease. Decitabine dosage: 20MG/M2 DAILY IV. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5546817-1
Decitabine side effect was reported by a Physician from CZECH REPUBLIC on Nov 23, 2007. Male patient, 78 years of age, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: febrile neutropenia, herpes simplex , leukopenia, pneumonitis. Decitabine dosage: 35.4 MG, 1 IN 1 DAY, INTRAVENOUS. During the same period patient was treated with ATENOLOL. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5400223-9
Decitabine side effect was reported by a Consumer or non-health professional from UNITED STATES on July 27, 2007. Male patient, 75 years of age, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: anaemia, condition aggravated, febrile neutropenia, myelodysplastic syndrome, thrombocytopenia. Decitabine dosage: 49MG OTHER IV. Patient was hospitalized. Patient recovered.


Decitabine Side Effects Report #5371367-5
Decitabine side effect was reported by a Physician from GERMANY on June 15, 2007. Male patient, 73 years of age, weighting 169.8 lb, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: febrile neutropenia. Decitabine dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient was hospitalized. Patient died on 02/05/2007.

Decitabine Side Effects Report #5623920-9
Decitabine side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Jan 24, 2008. Male patient, 72 years of age, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: abdominal tenderness, dysphonia, febrile neutropenia, odynophagia, tonsillitis. Decitabine dosage: 20 MG/M2, 1 IN 1 DAY, INTRAVENOUS. During the same period patient was treated with FELODIPINE, GLIPIZIDE, METFORMIN, MAGNESIUM OXIDE, SILYMARIN, SENNOSIDE A. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5626139-0
Decitabine side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Jan 31, 2008. Male patient, 72 years of age, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: abdominal tenderness, dysphonia, febrile neutropenia, haemoglobin decreased, odynophagia, platelet count decreased, tonsillitis, white blood cell count decreased. Decitabine dosage: 20 MG/M2, 1 IN 1 DAY, INTRAVENOUS. During the same period patient was treated with FELODIPINE, GLIPIZIDE, METFORMIN, MAGNESIUM OXIDE, SILYMARIN, SENNOSIDE A. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5652150-X
Decitabine side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Feb 22, 2008. Male patient, 72 years of age, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: abdominal tenderness, febrile neutropenia, haemoglobin decreased, odynophagia, platelet count decreased, tonsillitis. Decitabine dosage: 20 MG/M2, 1 IN 1 DAY, INTRAVENOUS; 20 MG/M2, 1 IN 1 DAY, INTRAVENOUS, 20 MG/M2, 1 IN 1 DAY, INTRAVEN. During the same period patient was treated with FELODIPINE, GLIPIZIDE, METFORMIN, MAGNESIUM OXIDE, SILYMARIN, SENNOSIDE A. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5698810-6
Decitabine side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Mar 21, 2008. Male patient, 72 years of age, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal tenderness, febrile neutropenia, hypertension, odynophagia, tonsillitis. Decitabine dosage: 20 MG/M2, 1 IN 1 DAY, INTRAVENOUS. Patient was hospitalized. Patient recovered.


Decitabine Side Effects Report #6122007-9
Decitabine side effect was reported by a Health Professional from UNITED STATES on Mar 01, 2009. Male patient, 71 years of age, weighting 229.3 lb, was diagnosed with acute myeloid leukaemia, electrocardiogram qt prolonged and was treated with Decitabine. After drug was administered, patient experienced the following side effects: bacterial infection , culture wound positive, diastolic dysfunction, electrocardiogram qt prolonged, enterococcal infection, febrile neutropenia, gout , myocardial infarction. Decitabine dosage: 20 MG/M2, 1 IN 1 DAY, INTRAVENOUS. During the same period patient was treated with FLUCONAZOLE. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5729580-0
Decitabine side effect was reported by a Physician from POLAND on Apr 22, 2008. Female patient, 70 years of age, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: bacteraemia, colitis, enterobacter infection, enterococcal infection, escherichia infection, febrile neutropenia, osteoporosis , refusal of treatment by patient, spinal compression fracture. Decitabine dosage: 32.4 MG, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5705219-5
Decitabine side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Apr 02, 2008. Male patient, 66 years of age, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, epistaxis, febrile neutropenia, head injury, headache , leukocytosis, thrombocytopenia. Decitabine dosage: 33.6 MG, 1 IN 1 DAY, INTRAVENOUS. During the same period patient was treated with ALLOPURINOL, PIOGLITAZONE, POTASSIUM CHLORIDE, CIMETIDINE, GLYCYRRHIZA, METOCLOPRAMIDE, BETAMETHASONE. Patient was hospitalized. Patient died on 01/04/2008.

Decitabine Side Effects Report #5663732-3
Decitabine side effect was reported by a Physician from UNITED STATES on Feb 25, 2008. Female patient, 65 years of age, was diagnosed with acute myeloid leukaemia, pneumonia fungal and was treated with Decitabine. After drug was administered, patient experienced the following side effects: abdominal hernia, abdominal pain , acute myeloid leukaemia recurrent, diabetes mellitus inadequate control, disease progression, febrile neutropenia, fluid overload, haematocrit decreased. Decitabine dosage: 20 MG/M2, IN 1 DAY, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5491226-7
Decitabine side effect was reported by a Physician from UNITED STATES on Oct 04, 2007. Female patient, 18 years of age, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: caecitis, cellulitis , cheilitis, electrocardiogram t wave abnormal, febrile neutropenia, lip pain, lip swelling, mouth injury, oral intake reduced. Decitabine dosage: 20 MG/M2, IN 1 DAY, INTRAVENOUS; 20 MG/M2, IN 1 DAY, INTRAVENOUS. During the same period patient was treated with VORINOSTAT. Patient was hospitalized. Patient recovered.


Decitabine Side Effects Report #5507072-1
Decitabine side effect was reported by a Physician from UNITED STATES on Oct 22, 2007. Female patient, 18 years of age, was diagnosed with acute myeloid leukaemia and was treated with Decitabine. After drug was administered, patient experienced the following side effects: caecitis, cellulitis , disease progression, electrocardiogram t wave abnormal, febrile neutropenia, mouth injury, oral intake reduced, weight decreased, white blood cell count decreased. Decitabine dosage: 20 MG/M2, IN 1 DAY, INTRAVENOUS. During the same period patient was treated with VORINOSTAT. Patient was hospitalized. Patient recovered.

Decitabine Side Effects Report #5565820-9
Decitabine side effect was reported by a Physician from TURKEY on Dec 05, 2007. Female patient, 64 years of age, weighting 163.1 lb, was treated with Decitabine. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, aspiration tracheal abnormal, bacterial infection , blood culture positive, caecitis, febrile neutropenia, haemorrhage intracranial, hepatic function abnormal, prothrombin time prolonged. Decitabine dosage: 225 MG, INTRAVENOUS. During the same period patient was treated with PIPERACILLIN TAZOBACTAM, AMIKACIN, PRIMAXIN, NETILMICIN SULPHATE, DEFEROXAMINE. Patient was hospitalized and became disabled. Patient died on 03/22/2007.

Decitabine Side Effects Report #5567424-0
Decitabine side effect was reported by a Physician from TURKEY on Dec 05, 2007. Female patient, 64 years of age, weighting 163.1 lb, was treated with Decitabine. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, bacterial infection , caecitis, febrile neutropenia, haemorrhage intracranial, hepatic function abnormal, prothrombin time prolonged, pseudomonas infection, renal impairment. Decitabine dosage: 225 MG, INTRAVENOUS. During the same period patient was treated with PIPERACILLIN TAZOBACTAM, AMIKACIN, PRIMAXIN, NETILMICIN SULPHATE, DEFEROXAMINE. Patient was hospitalized and became disabled. Patient died on 03/22/2007.

Decitabine Side Effects Report #5657879-5
Decitabine side effect was reported by a Physician from TURKEY on Feb 22, 2008. Female patient, 64 years of age, weighting 163.1 lb, was treated with Decitabine. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, caecitis, disease progression, febrile neutropenia, fibrin d dimer increased, haemorrhage intracranial, liver function test abnormal, platelet count decreased, prothrombin time prolonged. Decitabine dosage: 225 MG, INTRAVENOUS. During the same period patient was treated with PIPERACILLIN TAZOBACTAM, AMIKACIN, PRIMAXIN, NETILMICIN SULPHATE, DEFEROXAMINE. Patient was hospitalized and became disabled. Patient died on 03/22/2007.

Decitabine Side Effects Report #5729578-2
Decitabine side effect was reported by a Physician from TURKEY on Apr 22, 2008. Female patient, 64 years of age, weighting 163.1 lb, was treated with Decitabine. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, caecitis, disease progression, febrile neutropenia, haemoglobin decreased, haemorrhage intracranial, hepatic function abnormal, multi-organ failure, platelet count decreased. Decitabine dosage: 225 MG, INTRAVENOUS. Patient was hospitalized and became disabled. Patient died on 03/22/2007.