Comtan and neuroleptic malignant syndrome Patient Reports February 11, 2012

Comtan Side Effects Report #5524700-5
Comtan side effect was reported by a Consumer or non-health professional from FRANCE on Nov 16, 2007. Male patient, 71 years of age, was diagnosed with suicide attempt, parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: aphasia , blood creatine phosphokinase increased, confusional state, glasgow coma scale abnormal, intentional overdose, lung disorder, neuroleptic malignant syndrome, somnolence. Comtan dosage: unknown. During the same period patient was treated with RIVOTRIL, STALEVO, EFFERALGAN CODEINE, LACTULOSE, ALCOHOL. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5557971-X
Comtan side effect was reported by a Consumer or non-health professional from FRANCE on Nov 25, 2007. Male patient, 71 years of age, was diagnosed with suicide attempt, parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alcohol use, intentional overdose, lung disorder, neuroleptic malignant syndrome, suicide attempt, withdrawal syndrome. Comtan dosage: unknown. During the same period patient was treated with STALEVO, RIVOTRIL, ALCOHOL, EFFERALGAN, LACTULOSE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5318762-8
Comtan side effect was reported by a Consumer or non-health professional from FRANCE on Apr 10, 2007. Female patient, 78 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: calcinosis, cholelithiasis, dehydration, disease progression, escherichia urinary tract infection, hypertonia, neuroleptic malignant syndrome, parkinson's disease , renal cyst. Comtan dosage: 800 MG; 800 MG. During the same period patient was treated with MODOPAR, LAROXYL, DEROXAT, EQUANIL, SERESTA. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5353035-9
Comtan side effect was reported by a Consumer or non-health professional from FRANCE on May 18, 2007. Female patient, 78 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: calcinosis, cholelithiasis, dehydration, disease progression, escherichia infection, flatulence, neuroleptic malignant syndrome, parkinson's disease , pyelonephritis. Comtan dosage: 800 MG. During the same period patient was treated with MODOPAR, LAROXYL, DEROXAT, EQUANIL, SERESTA. Patient was hospitalized. Patient recovered.


Comtan Side Effects Report #4576363-3
Comtan side effect was reported by a Consumer or non-health professional from on Dec 10, 2004. Female patient, 78 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: depressed level of consciousness, neuroleptic malignant syndrome, respiratory disorder. Comtan dosage: 800-1000 MG. During the same period patient was treated with AMANTADINE, SINEMET. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #4603977-4
Comtan side effect was reported by a Consumer or non-health professional from on Dec 10, 2004. Female patient, 78 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: bronchitis , neuroleptic malignant syndrome, pneumonia , respiratory disorder. Comtan dosage: 800-1000 MG ORAL. During the same period patient was treated with AMANTADINE, SINEMET. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5661780-0
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Feb 20, 2008. Male patient, 77 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood urea increased, nausea , neuroleptic malignant syndrome, pneumonia aspiration. Comtan dosage: 300 MG (100 MG, 3 IN 1 D) ORAL. During the same period patient was treated with CARBIDOPA AND LEVODOPA, CABERGOLINE, LENDORMIN, WYPAX, FAMOTIDINE, GASMOTIN, MAGLAX. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5688222-3
Comtan side effect was reported by a Physician from JAPAN on Mar 05, 2008. Male patient, 77 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood urea increased, haematocrit decreased, haemoglobin decreased, nausea , neuroleptic malignant syndrome, parkinson's disease , pneumonia aspiration. Comtan dosage: 300 MG (100 MG,3 IN 1 D). During the same period patient was treated with LENDORMIN, WYPAX, FAMOTIDINE, GASMOTIN, CARBIDOPA AND LEVODOPA, CABERGOLINE, MAGLAX. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5772022-X
Comtan side effect was reported by a Physician from JAPAN on May 27, 2008. Male patient, 77 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood urea increased, condition aggravated, hyporeflexia, nausea , neuroleptic malignant syndrome, parkinson's disease , pneumonia aspiration. Comtan dosage: 300 MG (100 MG, 3 IN 1 D) ORAL. During the same period patient was treated with MENEST, CABASER, LENDORMIN, WYPAX, FAMOTIDINE, GASMOTIN, MAGLAX. Patient was hospitalized. Patient recovered.


Comtan Side Effects Report #5506076-2
Comtan side effect was reported by a Physician from JAPAN on Oct 26, 2007. Male patient, 72 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: neuroleptic malignant syndrome. Comtan dosage: unknown. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5528046-0
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Nov 03, 2007. Male patient, 72 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: neuroleptic malignant syndrome. Comtan dosage: unknown. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5337959-4
Comtan side effect was reported by a Physician from JAPAN on May 18, 2007. Male patient, 70 years of age, weighting 112.4 lb, was diagnosed with parkinson's disease , back pain  and was treated with Comtan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, fungal infection , gastritis erosive, gastritis haemorrhagic, haematemesis, neuroleptic malignant syndrome, pneumonia aspiration, pyrexia, sepsis . Comtan dosage: 100 MG, QID. During the same period patient was treated with HYPEN, MARZULENE S, NEO DOPASTON, CABASER, CYANOCOBALAMIN, SYMMETREL, HARNAL, LENDORMIN. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5360627-X
Comtan side effect was reported by a Physician from JAPAN on June 05, 2007. Male patient, 70 years of age, weighting 112.4 lb, was diagnosed with parkinson's disease , back pain  and was treated with Comtan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, fungal infection , gastritis erosive, gastritis haemorrhagic, haematemesis, neuroleptic malignant syndrome, oesophagitis haemorrhagic, pneumonia aspiration, pyrexia. Comtan dosage: 100 MG, QID. During the same period patient was treated with HYPEN, MARZULENE S, NEO DOPASTON, CABASER, CYANOCOBALAMIN, SYMMETREL, HARNAL, LENDORMIN. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5361546-5
Comtan side effect was reported by a Physician from JAPAN on June 05, 2007. Male patient, 70 years of age, weighting 112.4 lb, was diagnosed with parkinson's disease , back pain  and was treated with Comtan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, fungal infection , gastritis erosive, gastritis haemorrhagic, haematemesis, neuroleptic malignant syndrome, oesophagitis haemorrhagic, pneumonia aspiration, pyrexia. Comtan dosage: 100 MG, QID. During the same period patient was treated with HYPEN, MARZULENE S, NEO DOPASTON, CABASER, CYANOCOBALAMIN, SYMMETREL, HARNAL, LENDORMIN. Patient was hospitalized. Patient recovered.


Comtan Side Effects Report #5368513-6
Comtan side effect was reported by a Physician from JAPAN on May 30, 2007. Male patient, 70 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: condition aggravated, disseminated intravascular coagulation, fungal infection , gastritis erosive, gastritis haemorrhagic, haematemesis, neuroleptic malignant syndrome, pneumonia aspiration, pyrexia. Comtan dosage: 400 MG ORAL. During the same period patient was treated with MARZULENE S, NEO DOPASTON, CABASER, CYANOCOBALAMIN, SYMMETREL, HARNAL, LENDORMIN, MUCODYNE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5386438-7
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on June 19, 2007. Male patient, 70 years of age, was diagnosed with parkinson's disease , back pain  and was treated with Comtan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, fungal infection , gastritis erosive, gastritis haemorrhagic, neuroleptic malignant syndrome, oesophagitis haemorrhagic, pneumonia aspiration, reflux oesophagitis, sepsis . Comtan dosage: 400 MG. During the same period patient was treated with HYPEN, MARZULENE S, NEO DOPASTON, CABASER, METHYCOBAL, SYMMETREL, HARNAL, LENDORMIN. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5114133-8
Comtan side effect was reported by a Physician from SPAIN on Sept 12, 2006. Male patient, 68 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, infection , intubation, muscle contracture, neuroleptic malignant syndrome, pyrexia, tremor. Comtan dosage: unknown. During the same period patient was treated with SINEMET, PRAMIPEXOLE DIHYDROCHLORIDE, ARTANE, AMANTADINE, ENALAPRIL, OMEPRAZOLE, BRONCHODILATORS, AMITRIPTYLINE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5129952-1
Comtan side effect was reported by a Consumer or non-health professional from SPAIN on Sept 22, 2006. Male patient, 68 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: infection , neuroleptic malignant syndrome. Comtan dosage: unknown. During the same period patient was treated with SINEMET, PRAMIPEXOLE DIHYDROCHLORIDE, ARTANE, AMANTADINE, ENALAPRIL MALEATE, OMEPRAZOLE, BRONCHODILATORS, AMITRIPTYLINE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5901753-3
Comtan side effect was reported by a Physician from JAPAN on Sept 11, 2008. Male patient, 58 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: feeling abnormal, heat illness , hyponatraemia, neuroleptic malignant syndrome, temperature regulation disorder. Comtan dosage: 700 MG, ORAL. During the same period patient was treated with CARBIDOPA AND LEVODOPA, SYMMETREL, PRAMIPEXOLE DIHYDROCHLORIDE, MAGLAX, GASMOTIN, LORAZEPAM, SEVEN. Patient was hospitalized. Patient recovered.


Comtan Side Effects Report #5857365-3
Comtan side effect was reported by a Physician from JAPAN on Aug 19, 2008. Male patient, 55 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: neuroleptic malignant syndrome. Comtan dosage: 600 MG DAILY. During the same period patient was treated with CARBIDOPA AND LEVODOPA, SYMMETREL, PRAMIPEXOLE DIHYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5877377-3
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Aug 26, 2008. Male patient, 55 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: neuroleptic malignant syndrome. Comtan dosage: 600 MG, ORAL. During the same period patient was treated with CARBIDOPA AND LEVODOPA, SYMMETREL, PRAMIPEXOLE DIEHYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5783787-5
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on June 11, 2008. Male patient, 49 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: chromaturia, mobility decreased, neuroleptic malignant syndrome, rhabdomyolysis. Comtan dosage: unknown. During the same period patient was treated with MEVALOTIN, MENEST, PRAMIPEXOLE DIHYDROCHLORIDE, ARTANE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5939544-X
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on July 15, 2008. Male patient, 49 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: immobile, neuroleptic malignant syndrome, urinary incontinence . Comtan dosage: 400 MG (100 MG,4 IN 1 D). During the same period patient was treated with MEVALOTIN, CARBIDOPA, PRAMIPEXOLE DIHYDROCHLORIDE, ARTANE. Patient was hospitalized. Patient recovered.