Comtan and hepatic function abnormal Patient Reports February 11, 2012

Comtan Side Effects Report #5908980-X
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Sept 17, 2008. Female patient, 82 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood alkaline phosphatase abnormal, blood creatine phosphokinase increased, chromaturia, hepatic function abnormal, hypoaesthesia, musculoskeletal stiffness, refusal of treatment by patient. Comtan dosage: 400 MG (100 MG, 4 IN 1 D) ORAL. During the same period patient was treated with PARLODEL. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5579129-0
Comtan side effect was reported by a Physician from JAPAN on Dec 26, 2007. Male patient was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Comtan dosage: 500 MG/D. During the same period patient was treated with SYMMETREL, LEVODOPA BENSERAZIDE HYDROCHLO. Patient recovered.

Comtan Side Effects Report #5607727-4
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Jan 02, 2008. Male patient was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Comtan dosage: 500 MG, ORAL; 100 MG, ORAL; 200 MG, ORAL. During the same period patient was treated with SYMMETREL, LEVODOPA BENSERAZIDE HYDROCHLORIDE. Patient recovered.

Comtan Side Effects Report #5690136-X
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Mar 21, 2008. Female patient, 69 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase decreased, gamma-glutamyltransferase increased, hepatic function abnormal. Comtan dosage: 100 MG, TID. During the same period patient was treated with LEVODOPA BENSERAZIDE HYDROCHLO, SYMMETREL, PERMAX. Patient recovered.


Comtan Side Effects Report #5708757-4
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Mar 31, 2008. Female patient, 69 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Comtan dosage: 300 MG (100 MG, 3 IN 1 D) ORAL. During the same period patient was treated with LEVODOPA BENSERAZIDE, SYMMETREL, PERMAX. Patient recovered.

Comtan Side Effects Report #5826316-X
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on July 04, 2008. Female patient, 69 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Comtan dosage: 300 MG (100 MG, 3 IN 1 D) ORAL. During the same period patient was treated with LEVODOPA BENSERAZIDE, SYMMETREL, PERMAX, PRAMIPEXOLE DIHYDROCHLORIDE, LANSOPRAZOLE, GASMOTIN, VESICARE. Patient recovered.

Comtan Side Effects Report #5982105-7
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Nov 18, 2008. Female patient, 69 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Comtan dosage: 300 MG (100 MG, 3 IN 1 D) ORAL. During the same period patient was treated with LEVODOPA BENSERAZIDE, SYMMETREL, PERMAX, PRAMIPEXOLE DIHYDROCHLORIDE, TAKEPRON, GASMOTIN, VESICARE. Patient recovered.

Comtan Side Effects Report #5919697-X
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Sept 26, 2008. Male patient, 68 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: anorexia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, bone marrow failure, c-reactive protein increased, headache , hepatic function abnormal, hyperthermia, white blood cell count decreased. Comtan dosage: 500 MG, ORAL. During the same period patient was treated with NEODOPASOL, URSO, LEVODOPA BENSERAZIDE, PRAMIPEXOLE DIHYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5778817-0
Comtan side effect was reported by a Pharmacist from JAPAN on June 13, 2008. Female patient, 65 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: c-reactive protein increased, hepatic function abnormal, interstitial lung disease, viral infection . Comtan dosage: 500 MG, UNK. During the same period patient was treated with CARBIDOPA AND LEVODOPA, PRAMIPEXOLE DIHYDROCHLORIDE, PERMAX, SYMMETREL. Patient was hospitalized. Patient recovered.


Comtan Side Effects Report #5803922-X
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on June 19, 2008. Female patient, 65 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: hepatic function abnormal, interstitial lung disease, viral infection . Comtan dosage: 500 MG ORAL; 250 MG. During the same period patient was treated with CARBIDOPA AND LEVODOPA, PRAMIPEXOLE DIHYDROCHLORIDE, PERMAX, SYMMETREL. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5847385-7
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Aug 04, 2008. Female patient, 59 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, dyskinesia, hallucination, auditory, hepatic function abnormal, nausea . Comtan dosage: 600MG DIVIDED INTO 6 TIMES DAILY; ORAL; 400 MG, DIVIDED INTO 4 TIMES DAILY, ORAL. During the same period patient was treated with EC DOPARL, CARBIDOPA AND LEVODOPA. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5801130-X
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on June 25, 2008. Female patient was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase decreased, gamma-glutamyltransferase increased, hepatic function abnormal. Comtan dosage: 100 MG, TID. During the same period patient was treated with LEVODOPA BENSERAZIDE HYDROCHLO, SYMMETREL, PERMAX, SELEGILINE, PRAMIPEXOLE DIHYDROCHLORIDE, TAKEPRON, GASMOTIN, VESICARE. Patient recovered.

Comtan Side Effects Report #5832593-1
Comtan side effect was reported by a Physician from JAPAN on July 23, 2008. Female patient, weighting 77.16 lb, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: dyskinesia, hallucination, auditory, hepatic function abnormal, nausea . Comtan dosage: 600 MG, UNK. During the same period patient was treated with EC DOPARL, EC DOPARL, EC DOPARL, CARBIDOPA AND LEVODOPA. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5887515-4
Comtan side effect was reported by a Physician from JAPAN on Sept 10, 2008. Female patient, weighting 77.16 lb, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood lactate dehydrogenase increased, condition aggravated, dyskinesia, hallucination, auditory, hepatic function abnormal, malaise, nausea . Comtan dosage: 600 MG, UNK. During the same period patient was treated with EC DOPARL, EC DOPARL, EC DOPARL, CARBIDOPA AND LEVODOPA. Patient was hospitalized. Patient recovered.


Comtan Side Effects Report #5899553-6
Comtan side effect was reported by a Physician from JAPAN on Sept 18, 2008. Male patient was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: anorexia, aspartate aminotransferase increased, bone marrow failure, c-reactive protein increased, headache , hepatic function abnormal, hyperthermia, white blood cell count decreased. Comtan dosage: 500 MG. During the same period patient was treated with NEODOPASOL, URSO, LEVODOPA BENSERAZIDE HYDROCHLO, PRAMIPEXOLE DIHYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5956307-X
Comtan side effect was reported by a Physician from JAPAN on Nov 10, 2008. Female patient was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase decreased, gamma-glutamyltransferase increased, hepatic function abnormal. Comtan dosage: 100 MG, TID. During the same period patient was treated with LEVODOPA BENSERAZIDE HYDROCHLO, SYMMETREL, PERMAX, PRAMIPEXOLE DIHYDROCHLORIDE, LANSOPRAZOLE, GASMOTIN, VESICARE. Patient recovered.

Comtan Side Effects Report #6019595-X
Comtan side effect was reported by a Physician from JAPAN on Dec 17, 2008. Female patient, weighting 77.16 lb, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood lactate dehydrogenase increased, condition aggravated, dyskinesia, hallucination, auditory, hepatic function abnormal, malaise, nausea . Comtan dosage: 600 MG, UNK. During the same period patient was treated with EC DOPARL, EC DOPARL, EC DOPARL, CARBIDOPA AND LEVODOPA. Patient was hospitalized. Patient recovered.