Comtan and blood creatine phosphokinase increased Patient Reports February 11, 2012

Comtan Side Effects Report #5524700-5
Comtan side effect was reported by a Consumer or non-health professional from FRANCE on Nov 16, 2007. Male patient, 71 years of age, was diagnosed with suicide attempt, parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: aphasia , blood creatine phosphokinase increased, confusional state, glasgow coma scale abnormal, intentional overdose, lung disorder, neuroleptic malignant syndrome, somnolence. Comtan dosage: unknown. During the same period patient was treated with RIVOTRIL, STALEVO, EFFERALGAN CODEINE, LACTULOSE, ALCOHOL. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5908980-X
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Sept 17, 2008. Female patient, 82 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood alkaline phosphatase abnormal, blood creatine phosphokinase increased, chromaturia, hepatic function abnormal, hypoaesthesia, musculoskeletal stiffness, refusal of treatment by patient. Comtan dosage: 400 MG (100 MG, 4 IN 1 D) ORAL. During the same period patient was treated with PARLODEL. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5831892-7
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on July 22, 2008. Female patient, 80 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased. Comtan dosage: 400 MG (100 MG, 4 IN 1 D) ORAL. During the same period patient was treated with PARLODEL. Patient recovered.

Comtan Side Effects Report #5831898-8
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on July 17, 2008. Female patient, 80 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, refusal of treatment by patient. Comtan dosage: 400 MG (100 MG, 4 IN 1 D) ORAL. During the same period patient was treated with PARLODEL. Patient recovered.


Comtan Side Effects Report #6073335-7
Comtan side effect was reported by a Pharmacist from JAPAN on Feb 03, 2009. Female patient, 78 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: acidosis, alanine aminotransferase increased, altered state of consciousness, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood creatinine increased, blood lactate dehydrogenase increased, blood urea increased, disseminated intravascular coagulation. Comtan dosage: unknown. During the same period patient was treated with PRAMIPEXOLE DIHYDROCHLORIDE, CARBIDOPA, KARY UNI, XALATAN, CARTEOLOL HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #6088998-X
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Feb 05, 2009. Female patient, 78 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: acidosis, alanine aminotransferase increased, altered state of consciousness, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, disseminated intravascular coagulation, infection , liver disorder. Comtan dosage: 100 MG 3 TABLETS DAILY ORAL. During the same period patient was treated with PRAMIPEXOLE DIHYDROCHLORIDE, CARBIDOPA, KAY UNI, XALATAN, CARTEOLOL HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5631823-9
Comtan side effect was reported by a Physician from JAPAN on Feb 14, 2008. Male patient, 77 years of age, weighting 105.8 lb, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood urea increased, c-reactive protein increased, dysarthria, dysphagia, gastrointestinal tube insertion, hyporeflexia. Comtan dosage: 100 MG, TID. During the same period patient was treated with CARBIDOPA AND LEVODOPA, CABERGOLINE, LENDORMIN, WYPAX, GASTER, GASMOTIN, MAGLAX. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5650532-3
Comtan side effect was reported by a Physician from JAPAN on Feb 27, 2008. Male patient, 77 years of age, weighting 105.8 lb, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood urea increased, c-reactive protein increased, dysarthria, dysphagia, gastrointestinal tube insertion, haematocrit decreased. Comtan dosage: 100 MG, TID. During the same period patient was treated with CARBIDOPA AND LEVODOPA, CABERGOLINE, LENDORMIN, WYPAX, FAMOTIDINE, GASMOTIN, MAGLAX. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5659499-5
Comtan side effect was reported by a Physician from JAPAN on Mar 05, 2008. Male patient, 77 years of age, weighting 105.8 lb, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood urea increased, c-reactive protein increased, dysarthria, dysphagia, gastrointestinal tube insertion, haematocrit decreased. Comtan dosage: 100 MG, TID. During the same period patient was treated with CARBIDOPA AND LEVODOPA, CABERGOLINE, LENDORMIN, WYPAX, GASTER D, GASMOTIN, MAGLAX. Patient was hospitalized. Patient recovered.


Comtan Side Effects Report #5114133-8
Comtan side effect was reported by a Physician from SPAIN on Sept 12, 2006. Male patient, 68 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, infection , intubation, muscle contracture, neuroleptic malignant syndrome, pyrexia, tremor. Comtan dosage: unknown. During the same period patient was treated with SINEMET, PRAMIPEXOLE DIHYDROCHLORIDE, ARTANE, AMANTADINE, ENALAPRIL, OMEPRAZOLE, BRONCHODILATORS, AMITRIPTYLINE. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5032660-9
Comtan side effect was reported by a Consumer or non-health professional from ITALY on June 13, 2006. Male patient, 54 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, renal failure acute, rhabdomyolysis, urinary retention. Comtan dosage: 600 MG/D. During the same period patient was treated with SINEMET. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5751548-9
Comtan side effect was reported by a Physician from JAPAN on May 16, 2008. Male patient, weighting 105.8 lb, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood urea increased, c-reactive protein increased, dysarthria, dysphagia, gastrointestinal tube insertion, haematocrit decreased. Comtan dosage: 100 MG, TID. During the same period patient was treated with MENESIT, CABASER, LENDORMIN, WYPAX, GASTER D, GASMOTIN, MAGLAX. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5598162-6
Comtan side effect was reported by a Consumer or non-health professional from FRANCE on Jan 14, 2008. Female patient, 59 years of age, was diagnosed with intentional overdose and was treated with Comtan. After drug was administered, patient experienced the following side effects: agitation, blood creatine phosphokinase increased, confusional state, hallucination, hypokalaemia, hyponatraemia, intentional overdose, persecutory delusion, suicidal ideation. Comtan dosage: unknown. During the same period patient was treated with SINEMET. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5632289-5
Comtan side effect was reported by a Consumer or non-health professional from FRANCE on Jan 23, 2008. Male patient, 59 years of age, was diagnosed with intentional overdose and was treated with Comtan. After drug was administered, patient experienced the following side effects: agitation, blood creatine phosphokinase increased, confusional state, hallucination, hypokalaemia, hyponatraemia, nail discolouration, persecutory delusion. Comtan dosage: unknown. During the same period patient was treated with SINEMET. Patient was hospitalized. Patient recovered.


Comtan Side Effects Report #6066184-7
Comtan side effect was reported by a Pharmacist from JAPAN on Jan 27, 2009. Female patient, 78 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, liver disorder, renal failure. Comtan dosage: unknown. During the same period patient was treated with PRAMIPEXOLE DIHYDROCHLORIDE, CARBIDOPA. Patient recovered.

Comtan Side Effects Report #6093587-7
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Feb 12, 2009. Female patient, 76 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, altered state of consciousness, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood urea increased, contusion, fall , hallucination. Comtan dosage: 100 MG (100 MG, 1 IN 1 D), ORAL. During the same period patient was treated with PRAMIPEXOLE DIHYDROCHLORIDE, CARBIDOPA AND LEVODOPA, DOMIN, MAGLAX, BERIZYM, SELBEX, RHYTHMY. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5697434-4
Comtan side effect was reported by a Physician from on Mar 31, 2008. Male patient, 73 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased. Comtan dosage: 300 MG/DAY. During the same period patient was treated with CARBIDOPA AND LEVODOPA, PRAMIPEXOLE DIHYDROCHLORIDE. Patient recovered.

Comtan Side Effects Report #5713702-1
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Apr 07, 2008. Male patient, 73 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased. Comtan dosage: 300 MG ORAL. During the same period patient was treated with CARBIDOPA AND LEVODOPA, PRAMIPEXOLE DIHYDROCHLORIDE. Patient recovered.

Comtan Side Effects Report #5847385-7
Comtan side effect was reported by a Consumer or non-health professional from JAPAN on Aug 04, 2008. Female patient, 59 years of age, was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, dyskinesia, hallucination, auditory, hepatic function abnormal, nausea . Comtan dosage: 600MG DIVIDED INTO 6 TIMES DAILY; ORAL; 400 MG, DIVIDED INTO 4 TIMES DAILY, ORAL. During the same period patient was treated with EC DOPARL, CARBIDOPA AND LEVODOPA. Patient was hospitalized. Patient recovered.


Comtan Side Effects Report #5909047-7
Comtan side effect was reported by a Physician from JAPAN on Sept 18, 2008. Female patient, 59 years of age, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood creatine phosphokinase increased, blood glucose increased, blood lactate dehydrogenase increased, blood potassium decreased, dyskinesia. Comtan dosage: 600MG DIVIDED INTO 6 TIMES DAILY ORAL; 400 MG, DIVIDED INTO 4 TIMES DAILY ORAL. During the same period patient was treated with EC DOPARL, CARBIDOPA AND LEVODOPA. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #5670524-8
Comtan side effect was reported by a Physician from on Mar 11, 2008. Female patient was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased. Comtan dosage: 300 MG/DAY. Patient recovered.

Comtan Side Effects Report #5887515-4
Comtan side effect was reported by a Physician from JAPAN on Sept 10, 2008. Female patient, weighting 77.16 lb, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood lactate dehydrogenase increased, condition aggravated, dyskinesia, hallucination, auditory, hepatic function abnormal, malaise, nausea . Comtan dosage: 600 MG, UNK. During the same period patient was treated with EC DOPARL, EC DOPARL, EC DOPARL, CARBIDOPA AND LEVODOPA. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #6019595-X
Comtan side effect was reported by a Physician from JAPAN on Dec 17, 2008. Female patient, weighting 77.16 lb, was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood lactate dehydrogenase increased, condition aggravated, dyskinesia, hallucination, auditory, hepatic function abnormal, malaise, nausea . Comtan dosage: 600 MG, UNK. During the same period patient was treated with EC DOPARL, EC DOPARL, EC DOPARL, CARBIDOPA AND LEVODOPA. Patient was hospitalized. Patient recovered.

Comtan Side Effects Report #6020262-7
Comtan side effect was reported by a Health Professional from JAPAN on Dec 18, 2008. Female patient was diagnosed with parkinson's disease  and was treated with Comtan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, altered state of consciousness, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood urea increased, contusion, fall , hallucination, humerus fracture. Comtan dosage: 100 MG/DAY. During the same period patient was treated with E C DOPAL, PRAMIPEXOLE DIHYDROCHLORIDE, DOMIN, CARBIDOPA AND LEVODOPA, MAGLAX, BERIZYM, SELBEX. Patient was hospitalized. Patient recovered.