Clozapine and sepsis Patient Reports February 11, 2012

Clozapine Side Effects Report #4698832-8
Clozapine side effect was reported by a Physician from on June 21, 2005. Female patient, 83 years of age, weighting 149.0 lb, was diagnosed with schizophrenia, undifferentiated type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: cardiac arrest , pneumonia pneumococcal, sepsis , upper respiratory tract infection. Clozapine dosage: 175MG QD ORAL. During the same period patient was treated with ATENOLOL, DILTIAZEM, LIPITOR, METFORMIN, PAROXETINE, LORAZEPAM, TRAZODONE, LASIX. Patient was hospitalized. Patient died on 04/16/2005.

Clozapine Side Effects Report #4961787-2
Clozapine side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 14, 2006. Female patient, 38 years of age, weighting 148.0 lb, was diagnosed with schizophrenia, undifferentiated type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: ovarian cyst , peritonitis, sepsis , small intestinal obstruction. Clozapine dosage: 200 MG; QAM; ORAL; 400 MG; HS; ORAL. During the same period patient was treated with RISPERIDONE, BENZTROPINE MESYLATE, CLONIDINE, ROSUVASTATIN, DIPHENHYDRAMINE. Patient died on 01/07/2006.

Clozapine Side Effects Report #4587507-1
Clozapine side effect was reported by a Health Professional from on Jan 31, 2005. Male patient, 58 years of age, was diagnosed with schizophrenia, paranoid type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: bronchitis acute, dysphagia, influenza, leukopenia, pneumonia aspiration, sepsis . Clozapine dosage: 50 MG QD, ORAL. During the same period patient was treated with QUETIAPINE FUMARATE, RISPERIDONE, CLONAZEPAM. Patient was hospitalized. Patient died on 01/30/2005.

Clozapine Side Effects Report #4957945-3
Clozapine side effect was reported by a Physician from UNITED STATES on Dec 07, 2004. Female patient, 38 years of age, was diagnosed with schizophrenia, paranoid type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: agranulocytosis, hyperglycaemia, pyrexia, sepsis . Clozapine dosage: unknown. During the same period patient was treated with TOPAMAX, CELEXA. Patient was hospitalized. Patient recovered.


Clozapine Side Effects Report #4696257-2
Clozapine side effect was reported by a Consumer or non-health professional from on June 06, 2005. Female patient, 67 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: hypoglycaemia, sepsis . Clozapine dosage: 75 MG; HS; PO. Patient was hospitalized. Patient died on 05/29/2005.

Clozapine Side Effects Report #4761150-3
Clozapine side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 19, 2005. Female patient, 67 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: hypoglycaemia, sepsis . Clozapine dosage: 75 MG HS PO. During the same period patient was treated with RANITIDINE, FUROSEMIDE, VALPROIC ACID, SPIRONOLACTONE, ASPIRIN, FERROUS SULPHATE, FERROUS SULPHATE. Patient was hospitalized. Patient died on 05/29/2005.

Clozapine Side Effects Report #4602623-3
Clozapine side effect was reported by a Health Professional from on Mar 03, 2005. Male patient, 65 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: cerebrovascular accident, decubitus ulcer, gastrointestinal haemorrhage, mental disorder, sepsis . Clozapine dosage: 250 MG BID ORAL. During the same period patient was treated with DEPAKOTE, HYDROCHLOROTHIAZIDE, ZOCOR, GLYBURIDE, METFORMIN, LABETALOL, NORVASC, VITAMIN C. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #4819585-6
Clozapine side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 18, 2005. Male patient, 65 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: colitis ischaemic, sepsis . Clozapine dosage: 150 + 200 MG/QAM + QD + PO. During the same period patient was treated with DIGOXIN, LANSOPRAZOLE, DOCUSATE CALCIUM, LITHIUM CARBONATE, IPRATORPIUM BROMODE, VENLAFAXINE HYDROCHLORIDE, DOXAZOSIN MESYLATE. Patient died on 08/01/2005.

Clozapine Side Effects Report #4912978-8
Clozapine side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 27, 2006. Male patient, 65 years of age, weighting 165.0 lb, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: colitis ischaemic, sepsis . Clozapine dosage: unknown. During the same period patient was treated with MEGESTROL ACETATE, DIGOXIN, LANSOPRAZOLE, DOCUSATE CALCIUM, LITHIUM CARBONATE, TRIAMCINOLONE ACETONIDE, IPRATROPIUM BROMIDE, HYOSCINE BUTYLBROMIDE. Patient died on 08/01/2005.


Clozapine Side Effects Report #4698833-X
Clozapine side effect was reported by a Pharmacist from on June 15, 2005. Female patient, 64 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: sepsis . Clozapine dosage: 12.5-175MG QD ORAL. Patient died on 04/20/2005.

Clozapine Side Effects Report #4739873-1
Clozapine side effect was reported by a Pharmacist from UNITED STATES on Aug 03, 2005. Female patient, 64 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: infection , sepsis . Clozapine dosage: 12.5-175MG QD ORAL. Patient died on 04/20/2005.

Clozapine Side Effects Report #5300188-4
Clozapine side effect was reported by a Pharmacist from UNITED STATES on Apr 03, 2007. Male patient, 63 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: sepsis . Clozapine dosage: (450 MG), ORAL. Patient died on 03/13/2007.

Clozapine Side Effects Report #5331703-2
Clozapine side effect was reported by a Physician from UNITED STATES on May 07, 2007. Male patient, 63 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, respiratory failure, sepsis . Clozapine dosage: 450 MG, ORAL. Patient died on 03/12/2007.

Clozapine Side Effects Report #4591353-2
Clozapine side effect was reported by a Pharmacist from on Feb 05, 2004. Male patient, 54 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: blood creatinine increased, confusional state, diabetic ketoacidosis, pneumonia streptococcal, sepsis , white blood cell count decreased. Clozapine dosage: 100MG GAM AND 200MG HS, ORAL. During the same period patient was treated with ATENOLOL, PAROXETINE, QUETIAPINE FUMARATE, GEMFIBROZIL. Patient was hospitalized. Patient recovered.


Clozapine Side Effects Report #4615785-9
Clozapine side effect was reported by a Consumer or non-health professional from on Feb 05, 2005. Male patient, 54 years of age, weighting 166.7 lb, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: blood creatinine increased, confusional state, diabetic ketoacidosis, multi-organ failure, pneumonia streptococcal, sepsis , white blood cell count decreased. Clozapine dosage: unknown. During the same period patient was treated with ATENOLOL, PAROXETINE, HYDROCHLORIDE CR, QUETIAPINE, GEMFIBROZIL. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5284265-2
Clozapine side effect was reported by a Health Professional from UNITED KINGDOM on Mar 29, 2007. Male patient, 47 years of age, weighting 154.3 lb, was diagnosed with schizophrenia, depression  and was treated with Clozapine. After drug was administered, patient experienced the following side effects: colectomy total, intestinal perforation, malaise, megacolon, pain , renal failure, sepsis . Clozapine dosage: unknown. During the same period patient was treated with LOFEPRAMINE, SIMVASTATIN, TERBINAFINE, GLICLAZIDE, LISINOPRIL, NIFEDIPINE. Patient was hospitalized. Patient died on 03/17/2007.

Clozapine Side Effects Report #5300321-4
Clozapine side effect was reported by a Health Professional from UNITED KINGDOM on Apr 13, 2007. Male patient, 47 years of age, weighting 154.3 lb, was diagnosed with schizophrenia, depression  and was treated with Clozapine. After drug was administered, patient experienced the following side effects: colectomy total, intestinal perforation, malaise, megacolon, pain , renal failure, sepsis . Clozapine dosage: unknown. During the same period patient was treated with LOFEPRAMINE, SIMVASTATIN, TERBINAFINE, GLICLAZIDE, LISINOPRIL, NIFEDIPINE. Patient was hospitalized. Patient died on 03/17/2007.

Clozapine Side Effects Report #4617391-9
Clozapine side effect was reported by a Pharmacist from on Mar 22, 2005. Male patient, 47 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: sepsis . Clozapine dosage: 500-650MG QD ORAL. Patient died on 02/17/2005.

Clozapine Side Effects Report #4941987-8
Clozapine side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 21, 2006. Female patient, 38 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: ovarian cyst , peritonitis, sepsis , small intestinal obstruction. Clozapine dosage: 200 MG; QAM; ORAL; 400 MG; HS; ORAL. During the same period patient was treated with RISPERIDONE, BENZTROPINE MESYLATE, CLONIDINE, ROSUVASTATIN, DIPHENHYDRAMINE. Patient died on 01/07/2006.


Clozapine Side Effects Report #5033698-8
Clozapine side effect was reported by a Health Professional from FRANCE on June 20, 2006. Female patient, 30 years of age, weighting 160.9 lb, was diagnosed with schizophrenia, urinary incontinence , diaphragmatic hernia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal distension, cardio-respiratory arrest, metabolic acidosis, necrotising colitis, portal vein thrombosis, pyrexia, sepsis . Clozapine dosage: 200 MG, TID. During the same period patient was treated with SOLIAN, TEMESTA, MINIRIN, MOPRAL. Patient died.

Clozapine Side Effects Report #5728352-0
Clozapine side effect was reported by a Health Professional from UNITED KINGDOM on May 01, 2008. Male patient, 27 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: colitis ischaemic, constipation , pseudomembranous colitis, sepsis . Clozapine dosage: 300 MG/DAY. Patient died on 03/24/2008.

Clozapine Side Effects Report #5795562-6
Clozapine side effect was reported by a Physician from PHILIPPINES on June 27, 2008. Female patient was diagnosed with schizophrenia, trichotillomania, urinary tract infection  and was treated with Clozapine. After drug was administered, patient experienced the following side effects: mechanical ventilation, pneumonia , pulmonary oedema, pyrexia, sepsis , white blood cell count decreased. Clozapine dosage: 100 MG, QHS. During the same period patient was treated with HALOPERIDOL, AKINETON, FLUOXETINE, CIPROFLOXACIN. Patient was hospitalized. Patient died on 06/23/2008.

Clozapine Side Effects Report #6118805-8
Clozapine side effect was reported by a Health Professional from FINLAND on Mar 05, 2009. Female patient was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: agranulocytosis, epiglottitis, peritonsillitis, sepsis . Clozapine dosage: 0.3 MG/WEEK. During the same period patient was treated with FILGRASTIM. Patient recovered.

Clozapine Side Effects Report #4932058-5
Clozapine side effect was reported by a Pharmacist from UNITED STATES on Feb 17, 2006. Male patient, 71 years of age, was diagnosed with schizoaffective disorder and was treated with Clozapine. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, sepsis . Clozapine dosage: 400 MG, QD, ORAL. Patient was hospitalized. Patient died on 12/18/2005.


Clozapine Side Effects Report #4633965-3
Clozapine side effect was reported by a Consumer or non-health professional from on Mar 28, 2005. Female patient, 60 years of age, was diagnosed with schizoaffective disorder and was treated with Clozapine. After drug was administered, patient experienced the following side effects: sepsis . Clozapine dosage: 25 MG; QD; PO. During the same period patient was treated with LISINOPRIL, ESTROGENS CONJUGATED, CALCITONIN, VITAMINS, VITAMIN E, MOMETASONE FUROATE, TRAZODONE. Patient died on 02/26/2005.

Clozapine Side Effects Report #4649627-2
Clozapine side effect was reported by a Consumer or non-health professional from on Mar 28, 2005. Female patient, 60 years of age, was diagnosed with schizoaffective disorder and was treated with Clozapine. After drug was administered, patient experienced the following side effects: sepsis . Clozapine dosage: 25 MG;QD; PO. During the same period patient was treated with LISINOPRIL, ESTROGENS CONJUGATED, CALCITONIN, VITAMINS, VITAMIN E, MOMETASNE FUROATE, TRAZODONE. Patient died on 02/26/2005.

Clozapine Side Effects Report #4958471-8
Clozapine side effect was reported by a Health Professional from UNITED STATES on Aug 30, 2005. Female patient, 58 years of age, was diagnosed with schizoaffective disorder and was treated with Clozapine. After drug was administered, patient experienced the following side effects: sepsis . Clozapine dosage: 500 MG QD, ORAL. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5270835-4
Clozapine side effect was reported by a Pharmacist from UNITED STATES on Mar 19, 2007. Female patient, 60 years of age, weighting 153.0 lb, was diagnosed with psychotic disorder , schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: agranulocytosis, leukopenia, neutropenia, renal failure acute, sepsis , shock, urosepsis. Clozapine dosage: 150MG BID PO. Patient died on 02/03/2007.

Clozapine Side Effects Report #4911963-X
Clozapine side effect was reported by a Physician from NETHERLANDS on Jan 31, 2006. Male patient, 76 years of age, was diagnosed with hallucination and was treated with Clozapine. After drug was administered, patient experienced the following side effects: bladder catheter permanent, circulatory collapse, pulmonary embolism , pyelonephritis, respiratory arrest, sepsis , urinary retention, urinary tract infection . Clozapine dosage: 12.5 MG, BID. During the same period patient was treated with SIMVASTATIN, BISOPROLOL, CARBIDOPA AND LEVODOPA, PERGOLIDE, ACETYLSALICYLIC ACID SRT, ZYPREXA, LACTULOSE. Patient was hospitalized. Patient died on 01/25/2006.


Clozapine Side Effects Report #4654860-X
Clozapine side effect was reported by a Health Professional from on May 03, 2005. Female patient, 79 years of age, was diagnosed with dementia  and was treated with Clozapine. After drug was administered, patient experienced the following side effects: sepsis . Clozapine dosage: 100-300MG QD ORAL. Patient died on 05/02/2005.

Clozapine Side Effects Report #4698830-4
Clozapine side effect was reported by a Physician from on June 21, 2005. Male patient, 71 years of age, was diagnosed with dementia , parkinson's disease  and was treated with Clozapine. After drug was administered, patient experienced the following side effects: pneumonia aspiration, sepsis . Clozapine dosage: 75MG QHS ORAL. During the same period patient was treated with NAMENDA, ARICEPT, ASPIRIN, FOSAMAX, AMBIEN, COGENTIN, HALDOL. Patient was hospitalized. Patient died on 04/27/2005.

Clozapine Side Effects Report #5004508-X
Clozapine side effect was reported by a Pharmacist from UNITED STATES on May 16, 2006. Male patient, 22 years of age, weighting 286.6 lb, was diagnosed with bipolar disorder  and was treated with Clozapine. After drug was administered, patient experienced the following side effects: cardiac failure congestive, cardiomyopathy , pharyngolaryngeal pain, respiratory failure, sepsis . Clozapine dosage: 100 MG BID PO. During the same period patient was treated with METFORMIN, RISPERDAL, DEPAKOTE, BUSPAR, LEXAPRO, LEVAQUIN. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #4716545-0
Clozapine side effect was reported by a Pharmacist from UNITED STATES on July 08, 2005. Male patient, 72 years of age, was treated with Clozapine. After drug was administered, patient experienced the following side effects: hepatic failure, sepsis . Clozapine dosage: 12.5-125MG QD ORAL. Patient died on 07/02/2005.

Clozapine Side Effects Report #4768217-4
Clozapine side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 29, 2005. Male patient, 65 years of age, was treated with Clozapine. After drug was administered, patient experienced the following side effects: sepsis . Clozapine dosage: 150 MG; BID; PO. During the same period patient was treated with DIGOXIN, LANSOPRAZOLE, DOCUSATE CALCIUM, LITHIUM CARBONATE, IPRATROPIUM BROMIDE, HYOSCINE BUTYLBROMIDE, VENLAFAXINE, DOXAZOSIN MESYLATE. Patient died on 08/01/2005.


Clozapine Side Effects Report #4953485-6
Clozapine side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 21, 2005. Male patient, 51 years of age, was treated with Clozapine. After drug was administered, patient experienced the following side effects: pneumonia , sepsis , unevaluable event. Clozapine dosage: 350 MG QD, ORAL. Patient died on 10/15/2005.

Clozapine Side Effects Report #5148659-8
Clozapine side effect was reported by a Physician from UNITED STATES on Oct 30, 2006. Female patient, 37 years of age, was treated with Clozapine. After drug was administered, patient experienced the following side effects: appendicitis perforated, constipation , sepsis . Clozapine dosage: unknown. During the same period patient was treated with TOPIRAMATE, RISPERIDONE, VENLAFAXIINE, ESCITALOPRAM OXALATE. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5105593-7
Clozapine side effect was reported by a Physician from UNITED KINGDOM on Sept 06, 2006. Male patient, weighting 4167 lb, was treated with Clozapine. After drug was administered, patient experienced the following side effects: neutropenia neonatal, premature baby, sepsis . Clozapine dosage: unknown. Patient recovered.

Clozapine Side Effects Report #5788670-7
Clozapine side effect was reported by a Physician from PHILIPPINES on June 23, 2008. Female patient was treated with Clozapine. After drug was administered, patient experienced the following side effects: mechanical ventilation, pneumonia , pyrexia, sepsis , white blood cell count decreased. Clozapine dosage: 350 MG/DAY. Patient was hospitalized. Patient died on 06/23/2008.