Clozapine and constipation Patient Reports February 11, 2012

Clozapine Side Effects Report #4865268-6
Clozapine side effect was reported by a Health Professional from UNITED STATES on Dec 12, 2005. Male patient, 57 years of age, was diagnosed with schizophrenia, paranoid type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal distension, colon cancer, constipation , faecaloma, signet-ring cell carcinoma. Clozapine dosage: 550 MG, QD, ORAL. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #4953497-2
Clozapine side effect was reported by a Health Professional from UNITED STATES on Oct 04, 2005. Male patient, 57 years of age, was diagnosed with schizophrenia, paranoid type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , faecaloma. Clozapine dosage: 550 MG, QD, ORAL. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #4941988-X
Clozapine side effect was reported by a Health Professional from UNITED STATES on Feb 12, 2006. Female patient, 45 years of age, weighting 170.2 lb, was diagnosed with schizophrenia, paranoid type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: bronchitis , constipation , neutrophil count increased, white blood cell count increased. Clozapine dosage: 75 MG; QD; ORAL. During the same period patient was treated with LITHIUM, CLONAZEPAM, DOCUSATE, METOCLOPRAMIDE, LANSOPRAZOLE, SALBUTAMOL. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5491482-5
Clozapine side effect was reported by a Physician from INDIA on Oct 11, 2007. Male patient, 37 years of age, was diagnosed with schizophrenia, paranoid type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , oculogyric crisis. Clozapine dosage: 25 MG/DAY. During the same period patient was treated with TRIHEXYPHENIDYL. Patient recovered.


Clozapine Side Effects Report #6043792-0
Clozapine side effect was reported by a Health Professional from NETHERLANDS on Jan 14, 2009. Female patient, 37 years of age, was diagnosed with schizophrenia, paranoid type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: cervix carcinoma, constipation , diabetes mellitus, lymphadenopathy, metastatic neoplasm, obesity , obsessive-compulsive disorder , pulmonary embolism , schizophrenia, paranoid type. Clozapine dosage: unknown. Patient was hospitalized. Patient died.

Clozapine Side Effects Report #5512197-0
Clozapine side effect was reported by a Health Professional from CANADA on Nov 06, 2007. Male patient, 36 years of age, was diagnosed with schizophrenia, paranoid type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal discomfort, abdominal distension, abdominal wall operation, appendicectomy, circulatory collapse, constipation , hypotension, intubation, laparotomy. Clozapine dosage: GRADUALLY INCREASED TO 600 MG/DAY. During the same period patient was treated with CISAPRIDE, OMEPRAZOLE, DOCUSATE, PSYLLIUM HYDROPHILIC MUCILLOID, BENZTROPINE MESYLATE. Patient died.

Clozapine Side Effects Report #4919832-6
Clozapine side effect was reported by a Health Professional from UNITED STATES on Feb 02, 2006. Female patient was diagnosed with schizophrenia, paranoid type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: bronchitis , constipation , neutrophil count decreased, white blood cell count increased. Clozapine dosage: unknown. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5010651-1
Clozapine side effect was reported by a Health Professional from BRAZIL on May 17, 2006. Male patient, 30 years of age, was diagnosed with schizophrenia, disorganised type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , enuresis, obsessive-compulsive disorder , salivary hypersecretion, sedation. Clozapine dosage: 400 MG/D. Patient recovered.

Clozapine Side Effects Report #4928080-5
Clozapine side effect was reported by a Physician from FRANCE on Feb 09, 2006. Male patient, 19 years of age, weighting 143.3 lb, was diagnosed with schizophrenia, disorganised type and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal discomfort, abdominal pain , blood creatine phosphokinase increased, body temperature increased, constipation , faecaloma, gastrointestinal necrosis, large intestinal ulcer, malaise. Clozapine dosage: 400 MG, QD, ORAL. During the same period patient was treated with OLANZAPINE, VALPROATE, AMISULPRIDE, PAPAVER SOMNIFERUM TINCTURE, VALPROMIDE. Patient was hospitalized. Patient recovered.


Clozapine Side Effects Report #6036282-2
Clozapine side effect was reported by a Health Professional from HONG KONG on Jan 09, 2009. Female patient, 62 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal distension, constipation , faecaloma, intestinal obstruction, pulmonary oedema, urinary incontinence , vomiting. Clozapine dosage: 550 MG. Patient died.

Clozapine Side Effects Report #6058863-2
Clozapine side effect was reported by a Health Professional from HONG KONG on Jan 12, 2009. Female patient, 62 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , intestinal obstruction, pulmonary oedema, urinary incontinence . Clozapine dosage: 550 MG. Patient died.

Clozapine Side Effects Report #5061886-3
Clozapine side effect was reported by a Health Professional from SOUTH AFRICA on July 19, 2006. Male patient, 56 years of age, was diagnosed with schizophrenia, hypertension and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , convulsion, delusion, diarrhoea, hiccups, intestinal obstruction, malignant neoplasm progression, morbid thoughts, weight decreased. Clozapine dosage: 300-400 MG/D. During the same period patient was treated with ENALAPRIL MALEATE. Patient was hospitalized. Patient died.

Clozapine Side Effects Report #5601466-1
Clozapine side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 23, 2007. Male patient, 51 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , intestinal obstruction, vomiting. Clozapine dosage: 1-TABLET IN AM, AND 2-TABLETS AT NIGHT (100 MG,3 IN 1 D),ORAL. During the same period patient was treated with RISPERIDONE, VALPROATE, FLUOXETINE HYDROCHLORIDE, DOCUSATE. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #4948260-2
Clozapine side effect was reported by a Health Professional from UNITED STATES on Feb 18, 2005. Male patient, 43 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , intestinal obstruction. Clozapine dosage: 575MG QD, ORAL. During the same period patient was treated with LEXAPRO. Patient was hospitalized. Patient recovered.


Clozapine Side Effects Report #5271043-3
Clozapine side effect was reported by a Physician from BRAZIL on Mar 07, 2007. Male patient, 42 years of age, weighting 132.3 lb, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , eye disorder, urinary tract infection . Clozapine dosage: 300 MG, QD. Patient recovered.

Clozapine Side Effects Report #4679936-2
Clozapine side effect was reported by a Health Professional from on May 31, 2005. Male patient, 40 years of age, was diagnosed with schizophrenia, transient ischaemic attack, vomiting, salivary hypersecretion and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal pain , balance disorder, constipation , cyanosis, gastrointestinal haemorrhage, heart rate decreased, hyperhidrosis, hypotension, loss of consciousness. Clozapine dosage: 550MG/DAY. During the same period patient was treated with OMEPRAZOLE, ATORVASTATIN CALCIUM, ACETYLSALICYLATE, METOCLOPRAMIDE, PIRENZEPINE. Patient died on 12/19/2004.

Clozapine Side Effects Report #4696850-7
Clozapine side effect was reported by a Health Professional from on May 31, 2005. Male patient, 40 years of age, was diagnosed with schizophrenia, transient ischaemic attack, vomiting, salivary hypersecretion and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal pain , balance disorder, constipation , cyanosis, gastrointestinal haemorrhage, heart rate decreased, hyperhidrosis, hypotension, loss of consciousness. Clozapine dosage: 550MG/DAY. During the same period patient was treated with OMEPRAZOLE, ATORVASTATIN CALCIUM, ACETYLSALICYLATE, METOCLOPRAMIDE, PIRENZEPINE. Patient died on 12/19/2004.

Clozapine Side Effects Report #4696860-X
Clozapine side effect was reported by a Health Professional from on May 31, 2005. Male patient, 40 years of age, was diagnosed with schizophrenia, transient ischaemic attack, vomiting, salivary hypersecretion and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal pain , balance disorder, constipation , cyanosis, gastrointestinal haemorrhage, heart rate decreased, hyperhidrosis, hypotension, loss of consciousness. Clozapine dosage: 550MG/DAY. During the same period patient was treated with OMEPRAZOLE, ATORVASTATIN CALCIUM, ACETYLSALICYLATE, METOCLOPRAMIDE, PIRENZEPINE. Patient died on 12/19/2004.

Clozapine Side Effects Report #4746086-6
Clozapine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Aug 15, 2005. Male patient, 40 years of age, was diagnosed with schizophrenia, transient ischaemic attack, vomiting, salivary hypersecretion and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal pain , constipation , cyanosis, feeling abnormal, gait disturbance, gastrointestinal haemorrhage, heart rate decreased, hyperhidrosis, loss of consciousness. Clozapine dosage: 525-550 MG/DAY. During the same period patient was treated with ATORVASTATIN CALCIUM, ASPIRIN, METOCLOPRAMIDE, PIRENZEPINE, OMEPRAZOLE. Patient died on 12/19/2004.


Clozapine Side Effects Report #6010819-1
Clozapine side effect was reported by a Physician from MALAYSIA on Dec 15, 2008. Female patient, 33 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal pain , constipation , syncope. Clozapine dosage: 400 MG, QHS. During the same period patient was treated with AMITRIPTYLINE. Patient died on 10/15/2008.

Clozapine Side Effects Report #6016656-6
Clozapine side effect was reported by a Physician from MALAYSIA on Dec 18, 2008. Female patient, 33 years of age, was diagnosed with schizophrenia, salivary hypersecretion and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal pain , constipation , diarrhoea, gastrointestinal sounds abnormal, ileus paralytic, syncope. Clozapine dosage: 25 MG, QD. During the same period patient was treated with AMITRIPTYLINE. Patient died on 10/15/2008.

Clozapine Side Effects Report #6097905-5
Clozapine side effect was reported by a Physician from MALAYSIA on Feb 24, 2009. Female patient, 33 years of age, was diagnosed with schizophrenia, salivary hypersecretion and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal pain , constipation , diarrhoea, gastrointestinal sounds abnormal, ileus paralytic, megacolon, syncope. Clozapine dosage: 25 MG, QD. During the same period patient was treated with AMITRIPTYLINE. Patient died on 10/15/2008.

Clozapine Side Effects Report #5728352-0
Clozapine side effect was reported by a Health Professional from UNITED KINGDOM on May 01, 2008. Male patient, 27 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: colitis ischaemic, constipation , pseudomembranous colitis, sepsis . Clozapine dosage: 300 MG/DAY. Patient died on 03/24/2008.

Clozapine Side Effects Report #5169287-4
Clozapine side effect was reported by a Health Professional from UNITED KINGDOM on Nov 24, 2006. Male patient, 20 years of age, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal pain , circulatory collapse, constipation , faecaloma, intestinal infarction, intestinal ischaemia. Clozapine dosage: unknown. During the same period patient was treated with AMISULPRIDE. Patient died.


Clozapine Side Effects Report #4798377-0
Clozapine side effect was reported by a Health Professional from FRANCE on Oct 05, 2005. Male patient, 19 years of age, weighting 143.3 lb, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal discomfort, abdominal pain , blood creatine phosphokinase increased, blood pressure systolic decreased, body temperature increased, colectomy, constipation , diarrhoea, faecal disimpaction. Clozapine dosage: unknown. During the same period patient was treated with AMISULPRIDE, LAUDANUM, VALPROMIDE. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5010653-5
Clozapine side effect was reported by a Consumer or non-health professional from FRANCE on Oct 05, 2005. Male patient, 19 years of age, weighting 143.3 lb, was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal discomfort, abdominal pain , blood creatine phosphokinase increased, blood pressure systolic decreased, body temperature increased, colectomy, constipation , diarrhoea, faecal disimpaction. Clozapine dosage: unknown. During the same period patient was treated with AMISULPRIDE, LAUDANUM, VALPROMIDE. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #6113667-7
Clozapine side effect was reported by a Health Professional from UNITED STATES on Feb 27, 2009. Male patient was diagnosed with schizophrenia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal discomfort, ataxia , b-cell lymphoma, constipation , deep vein thrombosis , dyspnoea, folliculitis, lymphadenopathy. Clozapine dosage: 300 MG, BID. During the same period patient was treated with ARIPIPRAZOLE, ALLOPURINOL. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5827648-1
Clozapine side effect was reported by a Consumer or non-health professional from AUSTRALIA on July 17, 2008. Male patient, 53 years of age, was diagnosed with schizoaffective disorder and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , constipation , delirium, faecaloma, hyperhidrosis, hypotension, mental disorder, metabolic acidosis. Clozapine dosage: 700 MG, QD; 350 MG, QD. During the same period patient was treated with OLANZAPINE, FERROUS SULPHATE, LITHIUM CARBONATE, VITAMINS, PROTON PUMP INHIBITORS. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5417821-9
Clozapine side effect was reported by a Health Professional from UNITED KINGDOM on Aug 14, 2007. Male patient, 51 years of age, was diagnosed with schizoaffective disorder, constipation , extrapyramidal disorder and was treated with Clozapine. After drug was administered, patient experienced the following side effects: chest discomfort, constipation , respiratory failure. Clozapine dosage: 200MG/DAY. During the same period patient was treated with AMISULPRIDE, LITHIUM CARBONATE, MOVICOL, PROCYCLIDINE HYDROCHLORIDE, CLOMIPRAMINE. Patient died on 12/23/2006.


Clozapine Side Effects Report #4879696-6
Clozapine side effect was reported by a Physician from UNITED STATES on Jan 03, 2006. Female patient, 47 years of age, was diagnosed with schizoaffective disorder and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , faecaloma, hip fracture. Clozapine dosage: 300 MG, QD, ORAL. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #4622991-6
Clozapine side effect was reported by a Consumer or non-health professional from on Dec 13, 2004. Female patient, 65 years of age, was diagnosed with psychotic disorder , hypertension, thrombosis prophylaxis, depression  and was treated with Clozapine. After drug was administered, patient experienced the following side effects: cerebrovascular accident, constipation , loss of consciousness, rectal prolapse. Clozapine dosage: 325 MG NOCTE, PO. During the same period patient was treated with AMIODARONE, DIGOXIN, PERINDOPRIL, BENZTROPINE MESYLATE, ASPIRIN, DOXEPIN. Patient was hospitalized. Patient died.

Clozapine Side Effects Report #5143249-5
Clozapine side effect was reported by a Health Professional from UNITED STATES on Oct 31, 2006. Male patient, 48 years of age, weighting 197.0 lb, was diagnosed with bipolar disorder , schizoaffective disorder and was treated with Clozapine. After drug was administered, patient experienced the following side effects: appendicectomy, constipation , intestinal obstruction, vomiting. Clozapine dosage: 100 MG QAM + 200 MG QHS PO. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5164476-7
Clozapine side effect was reported by a Pharmacist from UNITED STATES on Nov 27, 2006. Female patient, 41 years of age, weighting 156.0 lb, was diagnosed with bipolar disorder , schizoaffective disorder and was treated with Clozapine. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, constipation , dysphagia, vomiting. Clozapine dosage: 50MG AM AND 100MG HS PO. Patient recovered.

Clozapine Side Effects Report #4664885-6
Clozapine side effect was reported by a Consumer or non-health professional from on May 10, 2005. Male patient, 57 years of age, weighting 136.0 lb, was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation . Clozapine dosage: unknown. Patient recovered.


Clozapine Side Effects Report #4953138-4
Clozapine side effect was reported by a Physician from UNITED STATES on May 13, 2005. Male patient, 44 years of age, was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , pancreatitis. Clozapine dosage: 350-500MG QD, ORAL. Patient recovered.

Clozapine Side Effects Report #5237848-X
Clozapine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 09, 2007. Female patient, 40 years of age, was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , diarrhoea, hypoalbuminaemia, leukocytosis, nasopharyngitis, neutrophilia, pericardial effusion, pleural effusion, pyrexia. Clozapine dosage: 125 MG, BID. During the same period patient was treated with OLANZAPINE. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5239507-6
Clozapine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 09, 2007. Female patient, 40 years of age, was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , diarrhoea, hypoalbuminaemia, leukocytosis, nasopharyngitis, neutrophilia, pericardial effusion, pleural effusion, pyrexia. Clozapine dosage: 125 MG, BID. During the same period patient was treated with OLANZAPINE. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5148659-8
Clozapine side effect was reported by a Physician from UNITED STATES on Oct 30, 2006. Female patient, 37 years of age, was treated with Clozapine. After drug was administered, patient experienced the following side effects: appendicitis perforated, constipation , sepsis . Clozapine dosage: unknown. During the same period patient was treated with TOPIRAMATE, RISPERIDONE, VENLAFAXIINE, ESCITALOPRAM OXALATE. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5176863-1
Clozapine side effect was reported by a Health Professional from UNITED KINGDOM on Dec 14, 2006. Male patient, 29 years of age, was treated with Clozapine. After drug was administered, patient experienced the following side effects: appendicectomy, appendicitis , constipation . Clozapine dosage: 800MG / DAY. During the same period patient was treated with AMISULPRIDE, AMOXICILLIN, DIAZEPAM, DOCUSATE, FLUOXETINE, HYOSCINE HYT, LACTULOSE, PROCYCLIDINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.


Clozapine Side Effects Report #4579223-7
Clozapine side effect was reported by a Pharmacist from on Feb 09, 2005. Male patient, 28 years of age, weighting 183.0 lb, was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , ileus paralytic, vomiting. Clozapine dosage: 400 MG HS. During the same period patient was treated with BENZTROPINE. Patient recovered.

Clozapine Side Effects Report #6031592-7
Clozapine side effect was reported by a Pharmacist from UNITED STATES on May 30, 2008. Male patient, 26 years of age, was diagnosed with drooling and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , intestinal obstruction. Clozapine dosage: (100 MG),ORAL. During the same period patient was treated with OXYBUTYNIN CHLORIDE. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #4958565-7
Clozapine side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 02, 2005. Male patient was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , dizziness , hypertension, obsessive-compulsive personality disorder, pain in extremity, psychotic disorder . Clozapine dosage: 50-500MG QD, ORAL. Patient was hospitalized. Patient recovered.

Clozapine Side Effects Report #5017745-5
Clozapine side effect was reported by a Consumer or non-health professional from GERMANY on May 24, 2006. Male patient was diagnosed with benign prostatic hyperplasia and was treated with Clozapine. After drug was administered, patient experienced the following side effects: constipation , disturbance in attention, dyspnoea, fatigue, hepatic steatosis, hyperhidrosis, hypertension, micturition disorder, parkinsonism. Clozapine dosage: unknown. During the same period patient was treated with TAVOR, LITHIUM CARBONATE, RAMIPRIL, ENALAPRIL, NEBILET, OMNIC. Patient recovered.