Clolar and coagulopathy Patient Reports February 13, 2012

Clolar Side Effects Report #5914957-0
Clolar side effect was reported by a Physician from UNITED STATES on Oct 02, 2008. Male patient, child 9 years of age, weighting 97.00 lb, was diagnosed with acute myeloid leukaemia and was treated with Clolar. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bilirubin conjugated increased, blood alkaline phosphatase increased, blood bilirubin increased, caecitis, cardiac failure, coagulopathy, conjunctival haemorrhage. Clolar dosage: 73 MG, ONCE, INTRAVENOUS; 36.5 MG, QD, INTRAVENOUS. During the same period patient was treated with CYTARABINE, METHYLPREDNISOLONE, ALLOPURINOL, CEFEPIME, PERIDEX, MORPHINE, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.

Clolar Side Effects Report #5961452-9
Clolar side effect was reported by a Physician from UNITED STATES on Nov 11, 2008. Male patient, child 9 years of age, weighting 97.00 lb, was diagnosed with acute myeloid leukaemia and was treated with Clolar. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bilirubin conjugated increased, blood alkaline phosphatase increased, blood bilirubin increased, caecitis, cardiac failure, coagulopathy, conjunctival haemorrhage. Clolar dosage: 73 MG, ONCE, INTRAVENOUS. During the same period patient was treated with CYTARABINE, METHYLPREDNISOLONE, ALLOPURINOL, CEFEPIME, PERIDEX, MORPHINE, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.

Clolar Side Effects Report #5894487-5
Clolar side effect was reported by a Physician from UNITED STATES on Sept 16, 2008. Male patient, child 10 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clolar. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, cardiac failure, coagulopathy, contusion, haemodialysis, haemoglobin decreased, hypotension, international normalised ratio increased, optic nerve sheath haemorrhage. Clolar dosage: unknown. Patient was hospitalized. Patient recovered.

Clolar Side Effects Report #5973855-7
Clolar side effect was reported by a Physician from UNITED STATES on Nov 14, 2008. Male patient, child 10 years of age, weighting 97.00 lb, was diagnosed with acute myeloid leukaemia and was treated with Clolar. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bilirubin conjugated increased, blood alkaline phosphatase increased, blood bilirubin increased, caecitis, cardiac failure, coagulopathy, conjunctival haemorrhage. Clolar dosage: 73 MG, ONCE, INTRAVENOUS; 36.5 MG, QD, INTRAVENOUS. During the same period patient was treated with CYCTARABINE, METHYLPREDNISOLONE, ALLOPURINOL, CEFEPIME, PERIDEX, MORPHINE. Patient was hospitalized and became disabled. Patient recovered.


Clolar Side Effects Report #6018769-1
Clolar side effect was reported by a Physician from UNITED STATES on Dec 17, 2008. Male patient, child 10 years of age, weighting 97.00 lb, was diagnosed with acute myeloid leukaemia and was treated with Clolar. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bilirubin conjugated increased, blood alkaline phosphatase increased, blood bilirubin increased, caecitis, cardiac failure, coagulopathy, conjunctival haemorrhage. Clolar dosage: 73 MG, ONCE, INTRAVENOUS; 36.5 MG. During the same period patient was treated with CYTARABINE, METHYLPREDNISOLONE, ALLOPURINOL, CEFEPIME, PERIDEX, MORPHINE. Patient was hospitalized and became disabled. Patient recovered.

Clolar Side Effects Report #6083355-4
Clolar side effect was reported by a Physician from UNITED STATES on Feb 04, 2009. Male patient, child 10 years of age, weighting 97.00 lb, was diagnosed with acute myeloid leukaemia and was treated with Clolar. After drug was administered, patient experienced the following side effects: caecitis, candidiasis, cardiac failure, chloroma, circulatory collapse, coagulopathy, conjunctival haemorrhage, contusion, convulsion. Clolar dosage: 73 MG, ONCE; INTRAVENOUS; 36.5 MG, QD; INTRAVENOUS. During the same period patient was treated with CYTARABINE, DAUNORUBICIN, ETOPOSIDE, METHYLPREDNISOLONE, ALLOPURINOL, CEFEPIME. Patient was hospitalized and became disabled. Patient died on 02/02/2009.

Clolar Side Effects Report #5713811-7
Clolar side effect was reported by a Physician from UNITED STATES on Apr 15, 2008. Male patient, child 12 years of age, weighting 80.25 lb, was diagnosed with acute lymphocytic leukaemia, myeloid leukaemia and was treated with Clolar. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, cardiomyopathy , chest pain , coagulopathy, dialysis , disease complication, febrile neutropenia, fibrosis. Clolar dosage: 36 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, NALOXONE. Patient was hospitalized. Patient died on 01/10/2008.

Clolar Side Effects Report #5752298-5
Clolar side effect was reported by a Physician from UNITED STATES on Apr 15, 2008. Male patient, child 12 years of age, weighting 80.25 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Clolar. After drug was administered, patient experienced the following side effects: blood creatinine increased, cardiomyopathy , cardiovascular disorder, chest pain , coagulopathy, dialysis , fat necrosis, febrile neutropenia. Clolar dosage: 36 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, NALOXONE, HYDROCORTISONE, VANCOMYCIN HYDROCHLORIDE, HYDROMORPHONE. Patient was hospitalized. Patient died on 01/10/2008.

Clolar Side Effects Report #5605142-0
Clolar side effect was reported by a Physician from UNITED STATES on Jan 11, 2008. Male patient, child 12 years of age, was diagnosed with acute leukaemia and was treated with Clolar. After drug was administered, patient experienced the following side effects: cardiomyopathy , coagulopathy, dialysis , disease complication, febrile neutropenia, hyperbilirubinaemia, hypotension, hypoxia. Clolar dosage: 36 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, NALOXONE, HYDROMORPHONE. Patient died on 01/10/2008.


Clolar Side Effects Report #5618416-4
Clolar side effect was reported by a Physician from UNITED STATES on Jan 29, 2008. Male patient, child 12 years of age, weighting 80.25 lb, was diagnosed with acute leukaemia and was treated with Clolar. After drug was administered, patient experienced the following side effects: blood creatinine increased, bone marrow failure, cardio-respiratory arrest, cardiomyopathy , chest pain , coagulopathy, culture positive, dialysis , disease complication. Clolar dosage: 36 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, NALOXONE, HYDROMORPHONE, HYDROCORTISONE, VANCOMYCIN HYDROCHLORIDE. Patient was hospitalized. Patient died on 01/19/2008.