Clofarabine and pneumonia Patient Reports February 11, 2012

Clofarabine Side Effects Report #5092258-3
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 15, 2006. Male patient, 59 years of age, was diagnosed with myelodysplastic syndrome and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: bacterial infection , blood culture positive, dialysis , hypotension, lung infiltration, pneumonia , renal failure acute, supraventricular tachycardia. Clofarabine dosage: 40 MG PO. During the same period patient was treated with AMBISOME, VANCOMYCIN. Patient was hospitalized. Patient died on 08/12/2006.

Clofarabine Side Effects Report #5098007-7
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 22, 2006. Male patient, 59 years of age, was diagnosed with myelodysplastic syndrome and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: hypotension, infection , pneumonia , renal failure acute, supraventricular tachycardia. Clofarabine dosage: 40 MG PO. During the same period patient was treated with AMBISOME, VANCOMYCIN, VORICONAZOLE. Patient was hospitalized. Patient died on 08/12/2006.

Clofarabine Side Effects Report #5509805-7
Clofarabine side effect was reported by a Physician from UNITED STATES on Sept 27, 2007. Female patient, 54 years of age, was diagnosed with myelodysplastic syndrome and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: pneumonia , supraventricular tachycardia. Clofarabine dosage: 30 MG/M2 QD X 3 PO. During the same period patient was treated with AMBIEN, CIPROFLOXACIN, CYMBALTA, LACTULOSE, LYRICA, METOPROLOL, MIRALAX, NEUPOGEN. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #5738494-1
Clofarabine side effect was reported by a Physician from UNITED STATES on May 07, 2008. Male patient, 51 years of age, weighting 233.7 lb, was diagnosed with myelodysplastic syndrome and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: bradycardia, effusion, hypotension, malignant neoplasm progression, pneumonia , pulmonary oedema. Clofarabine dosage: 40 MG/M2, QDX5, INTRAVENOUS. During the same period patient was treated with CYTARABINE, THYMOGLOBULIN, COMPAZINE, PAXIL, FAMOTIDINE, LISINOPRIL, MICONAZOLE. Patient was hospitalized. Patient died on 04/20/2008.


Clofarabine Side Effects Report #5301790-6
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Apr 16, 2007. Female patient, 68 years of age, weighting 185.4 lb, was diagnosed with lymphoma  and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: anaemia, leukopenia, neutropenia, pneumonia , thrombocytopenia. Clofarabine dosage: 4MG/M2 QD X 5 IV. During the same period patient was treated with ERYTHROPOIETINECTION. Patient recovered.

Clofarabine Side Effects Report #5271560-6
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Mar 08, 2007. Female patient, 34 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: acute respiratory failure, loss of consciousness, overdose, pneumonia , respiration abnormal. Clofarabine dosage: 40 MG/M2 QD X 5 IV. During the same period patient was treated with BUSULFAN, OPIOIDS, METHADONE. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #5993300-5
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Dec 10, 2008. Male patient, weighting 212.5 lb, was diagnosed with bone marrow conditioning regimen and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: pneumonia , respiratory distress. Clofarabine dosage: unknown. During the same period patient was treated with CAMPATH, MELPHALAN. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #4842769-8
Clofarabine side effect was reported by a Physician from UNITED STATES on Nov 11, 2005. Male patient, 81 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: atrial fibrillation , multi-organ failure, neutropenia, pneumonia . Clofarabine dosage: 57 MG QD X 5 IV. During the same period patient was treated with VASOPRESSIN, DEXMEDETOMIDINE, CALCIUM CHLORIDE, HYDROMORPHONE, MEROPENEM, CASPOFUNGIN, MIDAZOLAM. Patient died on 09/04/2005.

Clofarabine Side Effects Report #4842776-5
Clofarabine side effect was reported by a Physician from UNITED STATES on Nov 11, 2005. Male patient, 80 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: blood bilirubin increased, dialysis , neutropenia, pneumonia , renal failure. Clofarabine dosage: 57.9 MG QD X 5; IV. During the same period patient was treated with MAXIFLOXACIN, TRIMETHOPRIM, LINEZOID, ZOSYN, TYLENOL, DOCUSATE, FLOMAX, PROSCAR. Patient died on 12/12/2004.


Clofarabine Side Effects Report #5646790-1
Clofarabine side effect was reported by a Physician from UNITED KINGDOM on Feb 18, 2008. Female patient, 76 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: hepatic fibrosis, pneumonia . Clofarabine dosage: 35 MG, QDX5, INTRAVENOUS. During the same period patient was treated with GLICLAZIDE, METFORMIN, QUINE SULPHATE, ACARBOSE, TIMOLOL MALEATE. Patient died on 01/26/2008.

Clofarabine Side Effects Report #5274496-X
Clofarabine side effect was reported by a Physician from UNITED STATES on Mar 14, 2007. Female patient, 73 years of age, weighting 124.8 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: cholecystitis, depressed level of consciousness, febrile neutropenia, ileus paralytic, liver function test abnormal, pneumonia , renal failure, respiratory failure. Clofarabine dosage: 50 MG QD X 5 IV. Patient was hospitalized. Patient died on 03/14/2007.

Clofarabine Side Effects Report #5088626-6
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Aug 10, 2006. Male patient, 69 years of age, weighting 240.0 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: clostridial infection, enterocolitis infectious, febrile neutropenia, klebsiella infection, myalgia, pancytopenia, pneumonia , pyrexia. Clofarabine dosage: 30 MG/M2 DAILY IV. During the same period patient was treated with CYTOSINE ARABINOSIDE. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #4830351-8
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 04, 2005. Female patient, 69 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, blood creatinine increased, blood culture positive, dyspnoea, febrile neutropenia, pneumonia , pseudomonas infection, renal impairment, sepsis . Clofarabine dosage: 56.7 MG QD X 5 IV. During the same period patient was treated with MINOCYCLINE, ACYCLOVIR, COLISTIN, VORICONAZOLE, NEUPOGEN. Patient died on 04/08/2005.

Clofarabine Side Effects Report #4918390-X
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 02, 2006. Female patient, 69 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, bacteria blood identified, bacteria sputum identified, lung infection, neutropenic sepsis, pneumonia , pseudomonas infection, renal failure, staphylococcal infection . Clofarabine dosage: 56.7 MG QD X 5 IV. During the same period patient was treated with MINOCYCLINE, ACYCLOVIR, COLISTIN, VORICONAZOLE, NEUPOGEN. Patient died on 04/08/2005.


Clofarabine Side Effects Report #5077761-4
Clofarabine side effect was reported by a Physician from UNITED STATES on July 26, 2006. Male patient, 67 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, febrile neutropenia, pancytopenia, pneumonia , renal failure, sepsis . Clofarabine dosage: 87.2 MG DAILY IV. During the same period patient was treated with CYTARABINE, FLAGYL I, INSULIN, ATENOLOL, ALLOPURINOL, FAMVIR, ALTACE, LASIX. Patient died on 07/24/2006.

Clofarabine Side Effects Report #5105823-1
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Aug 29, 2006. Male patient, 67 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: bacterial infection , blood culture positive, febrile neutropenia, hypoxia, pancytopenia, pneumonia , renal failure, respiratory distress, respiratory failure. Clofarabine dosage: 87.2 MG DAILY IV. During the same period patient was treated with CYTARABINE, FLAGYL, NPH INSULIN, ATENOLOL, ALLOPURINOL, FAMVIR, ALTACE, LASIX. Patient died on 07/24/2006.

Clofarabine Side Effects Report #5599285-8
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Jan 11, 2008. Male patient, 67 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: acute respiratory failure, back pain , bone marrow failure, hypotension, lung infection, pneumonia . Clofarabine dosage: 39 MG, QDX5, INTRAVENOUS. During the same period patient was treated with IDARUBICIN, CYTARABINE, PANTOPRAZOLE, AZTREONAM, CLINDAMYCIN, ZYVOX, DILAUDID, SENOKOT. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #5604873-6
Clofarabine side effect was reported by a Physician from UNITED STATES on Jan 16, 2008. Male patient, 67 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: acute respiratory failure, back pain , bone marrow failure, confusional state, hypotension, lung infection, pneumonia . Clofarabine dosage: 39 MG, QDX5, INTRAVENOUS. During the same period patient was treated with IDARUBICIN, CYTARABINE, PANTOPRAZOLE, AZTREONAM, CLINDAMYCIN, ZYVOX, DILAUDID, SENOKOT. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #5637768-2
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Feb 13, 2008. Male patient, 67 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: acute respiratory failure, bone marrow failure, confusional state, hypotension, hypoxia, lung infection, pneumonia . Clofarabine dosage: 39 MG, QDX5, INTRAVENOUS. During the same period patient was treated with IDARUBICIN, CYTARABINE, PANTOPRAZOLE, AZTREONAM, CLINDAMYCIN, ZYVOX, DILAUDID, SENOKOT. Patient was hospitalized. Patient recovered.


Clofarabine Side Effects Report #5509079-7
Clofarabine side effect was reported by a Physician from UNITED STATES on July 03, 2007. Male patient, 63 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: blood bilirubin increased, periorbital haematoma, pneumonia , renal failure acute, respiratory failure, sepsis , traumatic intracranial haemorrhage. Clofarabine dosage: 47 MG QD X 5 IV. During the same period patient was treated with IDARUBICIN, CYTARABINE, PREDTE, XOPENEX, ATROVENT, ZOSYN, TIGECYCLINE. Patient was hospitalized. Patient died on 07/19/2007.

Clofarabine Side Effects Report #4800758-3
Clofarabine side effect was reported by a Physician from UNITED KINGDOM on Oct 04, 2005. Male patient, 60 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, febrile neutropenia, neutropenic sepsis, pneumonia , thrombocytopenia. Clofarabine dosage: 20 MG/M2 QD IV. During the same period patient was treated with ACYCLOVIR, NYSTATIN, ITRACONAZOLE, GENTAMICIN, CEFTAZIDIME, CLARITHROMYCIN, IMIPENEM. Patient was hospitalized. Patient died on 06/17/2005.

Clofarabine Side Effects Report #5230396-2
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Jan 18, 2007. Female patient, 57 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: diarrhoea, disseminated intravascular coagulation, mucosal inflammation, neutropenic sepsis, pneumonia , pulmonary haemorrhage, staphylococcal infection . Clofarabine dosage: 35 MG QD IV. During the same period patient was treated with CYTARABINE. Patient died on 12/07/2006.

Clofarabine Side Effects Report #5242685-6
Clofarabine side effect was reported by a Physician from UNITED KINGDOM on Jan 31, 2007. Female patient, 57 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: diarrhoea, disseminated intravascular coagulation, mucosal inflammation, neutropenic sepsis, pneumonia , pulmonary haemorrhage, staphylococcal infection . Clofarabine dosage: 20 MG/M2 QD IV. During the same period patient was treated with CYTARABINE. Patient died on 12/07/2006.

Clofarabine Side Effects Report #5056572-X
Clofarabine side effect was reported by a Physician from UNITED STATES on June 30, 2006. Male patient, 48 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: febrile neutropenia, pathogen resistance, pneumonia , staphylococcal bacteraemia. Clofarabine dosage: 46.8 MG QD X 5 IV. During the same period patient was treated with IDARUBICIN, MAGNESIUM SULPHATE, POTASSIUM CHLORIDE, POTASSIUM PHOSPHATES, PHOSPHATES, INSULIN, BACLOFEN, LINEZOLID. Patient was hospitalized. Patient recovered.


Clofarabine Side Effects Report #5064429-3
Clofarabine side effect was reported by a Physician from UNITED STATES on July 12, 2006. Male patient, 48 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: bone marrow failure, febrile neutropenia, pneumonia , staphylococcal bacteraemia, syncope. Clofarabine dosage: 46.8 MG QD X 5 IV. During the same period patient was treated with IDARUBICIN, MAGNESIUM SULPHATE, POTASSIUM CHLORIDE, POTASSIUM PHOSPHATES, PHOSPHATES, INSULIN, BACLOFEN, LINEZOLID. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #5115023-7
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Sept 08, 2006. Male patient, 48 years of age, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: bone marrow failure, cholecystitis, febrile neutropenia, pathogen resistance, pneumonia , streptococcal bacteraemia, syncope. Clofarabine dosage: 46.8 MG QD X 5 IV. During the same period patient was treated with IDARUBICIN, MAGNESIUM SULPHATE, POTASSIUM CHLORIDE, POTASSIUM PHOSPHATES, PHOSPHATES, INSULIN, BACLOFEN, LINEZOLID. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #5566522-5
Clofarabine side effect was reported by a Physician from UNITED STATES on Dec 10, 2007. Female patient, 46 years of age, weighting 117.1 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: aggression, agitation, bipolar disorder , condition aggravated, cytomegalovirus test positive, hallucination, pleural effusion, pneumonia , pneumonitis. Clofarabine dosage: 30 MG/M2 IV. During the same period patient was treated with FLUDARABINE PHOSPHATE, BUSULFAN. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #4869712-X
Clofarabine side effect was reported by a Consumer or non-health professional from IRELAND on Dec 14, 2005. Female patient was diagnosed with acute myeloid leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: dialysis , pneumonia , renal failure acute. Clofarabine dosage: 52 MG QD X 5 IV. During the same period patient was treated with FUROSEMIDE, TAZOCIN, GENTAMICIN. Patient recovered.

Clofarabine Side Effects Report #5527717-X
Clofarabine side effect was reported by a Health Professional from UNITED STATES on Nov 13, 2007. Male patient, 20 years of age, weighting 118.2 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, febrile neutropenia, hyperbilirubinaemia, infection , lung infiltration, pleural effusion, pneumonia , pulmonary haemorrhage. Clofarabine dosage: 68 MG QD IV. During the same period patient was treated with ETOPOSIDE, CYCLOPHOSPHAMIDE, ACETAMINOPHEN, ACYCLOVIR, ALLOPURINOL, CEFEPIME, BENADRYL, DRONABINOL. Patient was hospitalized. Patient recovered.


Clofarabine Side Effects Report #4950422-5
Clofarabine side effect was reported by a Consumer or non-health professional from FRANCE on Mar 01, 2006. Female patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: acute lymphocytic leukaemia, bronchopulmonary aspergillosis, febrile bone marrow aplasia, malignant neoplasm progression, pleural effusion, pneumonia . Clofarabine dosage: 52 MG/M2 QD X 5 IV. During the same period patient was treated with AMBISOME, CEFTAZIDIME, VANCOMYCIN, AMIKACIN, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #5009178-2
Clofarabine side effect was reported by a Physician from SPAIN on May 05, 2006. Male patient, child 12 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: aplasia, bone marrow failure, interstitial lung disease, neutropenia, pneumonia , septic shock. Clofarabine dosage: 52 MG/M2 QD IV. During the same period patient was treated with LINEZOLID, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.

Clofarabine Side Effects Report #5629838-X
Clofarabine side effect was reported by a Physician from UNITED KINGDOM on Jan 31, 2008. Female patient, 76 years of age, was diagnosed with acute leukaemia and was treated with Clofarabine. After drug was administered, patient experienced the following side effects: pneumonia . Clofarabine dosage: unknown. Patient died on 01/26/2008.

Clofarabine Side Effects Report #4774499-5
Clofarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 09, 2005. Male patient was treated with Clofarabine. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, febrile neutropenia, pneumonia . Clofarabine dosage: 20 MG/M2 QD IV. Patient was hospitalized. Patient died on 06/17/2005.