Cerezyme and sepsis Patient Reports February 11, 2012

Cerezyme Side Effects Report #5216832-6
Cerezyme side effect was reported by a Health Professional from UNITED STATES on Jan 08, 2007. Female patient, 84 years of age, weighting 110.2 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: emphysema, sepsis . Cerezyme dosage: unknown. Patient died on 12/01/2006.

Cerezyme Side Effects Report #5245658-2
Cerezyme side effect was reported by a Physician from UNITED STATES on Feb 05, 2007. Female patient, 84 years of age, weighting 110.2 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: condition aggravated, emphysema, pneumonia , sepsis . Cerezyme dosage: unknown. Patient was hospitalized. Patient died on 12/24/2006.

Cerezyme Side Effects Report #5404961-3
Cerezyme side effect was reported by a Physician from UNITED STATES on July 24, 2007. Female patient, 84 years of age, weighting 132.3 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: pneumonia , respiratory failure, sepsis . Cerezyme dosage: unknown. Patient was hospitalized. Patient died on 06/08/2007.

Cerezyme Side Effects Report #5465296-6
Cerezyme side effect was reported by a Physician from UNITED STATES on Sept 13, 2007. Female patient, 82 years of age, weighting 127.9 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: coronary artery disease , device migration, dislocation of joint prosthesis, hip fracture, localised infection, myocardial infarction, sepsis , splenectomy, thrombocytopenia. Cerezyme dosage: unknown. Patient died on 06/02/2007.


Cerezyme Side Effects Report #5755014-6
Cerezyme side effect was reported by a Physician from UNITED STATES on May 15, 2008. Female patient, 69 years of age, weighting 162.3 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: central nervous system lymphoma, neutropenia, sepsis . Cerezyme dosage: unknown. Patient was hospitalized. Patient died on 05/10/2008.

Cerezyme Side Effects Report #5764546-6
Cerezyme side effect was reported by a Physician from UNITED STATES on May 30, 2008. Female patient, 69 years of age, weighting 162.3 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: central nervous system lymphoma, neutropenia, sepsis . Cerezyme dosage: unknown. Patient was hospitalized. Patient died on 05/10/2008.

Cerezyme Side Effects Report #5309221-7
Cerezyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 09, 2007. Female patient, 65 years of age, weighting 60.00 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: blood culture positive, chills, pyrexia, sepsis , tremor. Cerezyme dosage: unknown. Patient was hospitalized. Patient recovered.

Cerezyme Side Effects Report #5320810-6
Cerezyme side effect was reported by a Physician from UNITED STATES on Apr 19, 2007. Female patient, 65 years of age, weighting 132.3 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: blood culture positive, catheter related infection, sepsis , staphylococcal infection . Cerezyme dosage: unknown. Patient was hospitalized. Patient recovered.

Cerezyme Side Effects Report #5223498-8
Cerezyme side effect was reported by a Physician from UNITED STATES on Jan 11, 2007. Female patient, 56 years of age, weighting 149.9 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: angioplasty , infection , portal hypertension, sepsis , treatment noncompliance. Cerezyme dosage: unknown. Patient was hospitalized. Patient died on 11/22/2006.


Cerezyme Side Effects Report #5135755-4
Cerezyme side effect was reported by a Physician from UNITED STATES on Oct 11, 2006. Female patient, 55 years of age, weighting 147.0 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: catheter related infection, sepsis . Cerezyme dosage: unknown. Patient recovered.

Cerezyme Side Effects Report #4768020-5
Cerezyme side effect was reported by a Health Professional from UNITED STATES on Aug 30, 2005. Female patient, 55 years of age, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: sepsis . Cerezyme dosage: unknown. Patient died on 08/20/2005.

Cerezyme Side Effects Report #4952367-3
Cerezyme side effect was reported by a Physician from UNITED STATES on Mar 06, 2006. Male patient, 51 years of age, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bacterial infection , dialysis , post procedural complication, pulmonary oedema, renal failure, sepsis . Cerezyme dosage: unknown. Patient was hospitalized. Patient recovered.

Cerezyme Side Effects Report #5093429-2
Cerezyme side effect was reported by a Physician from JAPAN on Aug 18, 2006. Male patient, child 5 years of age, weighting 33.07 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, dialysis , hepatitis fulminant, sepsis . Cerezyme dosage: unknown. During the same period patient was treated with VALPROATE, POTASSIUM BROMIDE, PHENOBARBITAL, PHENYTOIN. Patient was hospitalized. Patient died on 04/22/2006.

Cerezyme Side Effects Report #5494567-2
Cerezyme side effect was reported by a Physician from JAPAN on Oct 11, 2007. Male patient, child 5 years of age, weighting 33.07 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, dialysis , hepatitis fulminant, sepsis . Cerezyme dosage: unknown. During the same period patient was treated with VALPROATE, POTASSIUM BROMIDE, PHENOBARBITAL, PHENYTOIN, HALOPERIDOL, CLONAZEPAM, MOSAPRIDE CITRATE, MECOBALAMIN. Patient died on 04/22/2006.


Cerezyme Side Effects Report #4992531-0
Cerezyme side effect was reported by a Physician from JAPAN on Apr 24, 2006. Male patient, child 5 years of age, weighting 33.07 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, dialysis , hepatitis fulminant, sepsis . Cerezyme dosage: unknown. During the same period patient was treated with VALPROATE, POTASSIUM BROMIDE, PHENOBARBITAL, PHENYTOIN. Patient was hospitalized. Patient died on 04/22/2006.

Cerezyme Side Effects Report #5738064-5
Cerezyme side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Apr 10, 2008. Female patient, 37 years of age, weighting 81.13 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: chronic hepatitis, epistaxis, gastrointestinal haemorrhage, haemorrhagic anaemia, hepatic cancer metastatic, hypoalbuminaemia, refusal of treatment by patient, sepsis , spinal compression fracture. Cerezyme dosage: 60 MG/KG, Q2W, INTRAVENOUS. Patient died on 04/29/2008.

Cerezyme Side Effects Report #6032713-2
Cerezyme side effect was reported by a Physician from UNITED STATES on Dec 30, 2008. Female patient, 28 years of age, weighting 104.1 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: escherichia urinary tract infection, infusion related reaction, leukocytosis, sepsis . Cerezyme dosage: unknown. During the same period patient was treated with LORTAB, ACTONEL. Patient was hospitalized. Patient recovered.

Cerezyme Side Effects Report #5622334-5
Cerezyme side effect was reported by a Physician from ITALY on Jan 23, 2008. Male patient, child 2 years of age, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Cerezyme dosage: unknown. Patient died on 11/03/2007.

Cerezyme Side Effects Report #5691906-4
Cerezyme side effect was reported by a Physician from KOREA, REPUBLIC OF on Mar 27, 2008. Female patient, child 2 years of age, weighting 14.77 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, myoclonic epilepsy, pneumonia aspiration, sepsis . Cerezyme dosage: unknown. Patient was hospitalized. Patient died on 03/13/2008.


Cerezyme Side Effects Report #5702462-6
Cerezyme side effect was reported by a Health Professional from KOREA, REPUBLIC OF on Mar 31, 2008. Female patient, child 2 years of age, weighting 14.77 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, myoclonic epilepsy, pneumonia aspiration, sepsis . Cerezyme dosage: unknown. Patient was hospitalized. Patient died on 03/13/2008.

Cerezyme Side Effects Report #5828361-7
Cerezyme side effect was reported by a Physician from KOREA, REPUBLIC OF on July 28, 2008. Female patient, child 2 years of age, weighting 6.70 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, myoclonic epilepsy, pneumonia aspiration, sepsis . Cerezyme dosage: unknown. Patient was hospitalized. Patient died on 03/13/2008.

Cerezyme Side Effects Report #5775743-8
Cerezyme side effect was reported by a Physician from JAPAN on June 06, 2008. Female patient, 19 years of age, weighting 66.14 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: acinetobacter infection, infusion site infection, sepsis , staphylococcal infection . Cerezyme dosage: unknown. Patient was hospitalized. Patient recovered.

Cerezyme Side Effects Report #4735058-3
Cerezyme side effect was reported by a Consumer or non-health professional from UNITED STATES on July 20, 2005. Female patient, 19 years of age, weighting 66.14 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: asthenia, dehydration, failure to thrive, oral intake reduced, sepsis , weight decreased. Cerezyme dosage: unknown. Patient was hospitalized. Patient recovered.

Cerezyme Side Effects Report #5369687-3
Cerezyme side effect was reported by a Physician from UNITED STATES on June 08, 2007. Female patient, weighting 127.9 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: coronary artery disease , device migration, disease recurrence, dislocation of joint prosthesis, femur fracture, infection , myocardial infarction, sepsis , thrombocytopenia. Cerezyme dosage: unknown. Patient died on 06/02/2007.


Cerezyme Side Effects Report #5755671-4
Cerezyme side effect was reported by a Physician from JAPAN on May 20, 2008. Female patient, weighting 15.43 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: cardiac failure, cardio-respiratory arrest, catheter related infection, endotoxic shock, respiratory failure, sepsis . Cerezyme dosage: unknown. Patient recovered.

Cerezyme Side Effects Report #4745661-2
Cerezyme side effect was reported by a Physician from BRAZIL on July 29, 2005. Male patient, weighting 17.24 lb, was diagnosed with gaucher's disease and was treated with Cerezyme. After drug was administered, patient experienced the following side effects: multi-organ failure, pneumonia , sepsis . Cerezyme dosage: unknown. Patient was hospitalized. Patient died on 07/27/2005.