Campath and abdominal distension Patient Reports February 11, 2012

Campath Side Effects Report #5799904-7
Campath side effect was reported by a Physician from UNITED STATES on June 25, 2008. Male patient, 79 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, asthenia, b-cell lymphoma, blood albumin decreased, blood calcium decreased. Campath dosage: UNIT DOSE: 30 MG. During the same period patient was treated with RITUXAN, FLUDARA, ALLOPURINOL, DIPHENHYDRAMINE, ACETAMINOPHEN, DAPSONE, VALTREX. Patient was hospitalized. Patient recovered.

Campath Side Effects Report #5570797-6
Campath side effect was reported by a Physician from UNITED STATES on Dec 12, 2007. Male patient, 75 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, liver function test abnormal, nausea . Campath dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, RITUXIMAB. Patient was hospitalized. Patient died on 11/14/2007.

Campath Side Effects Report #5574238-4
Campath side effect was reported by a Physician from UNITED STATES on Dec 12, 2007. Male patient, 75 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, liver function test abnormal, nausea . Campath dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, RITUXIMAB. Patient was hospitalized. Patient died on 11/14/2007.

Campath Side Effects Report #5582879-3
Campath side effect was reported by a Health Professional from UNITED STATES on Dec 28, 2007. Male patient, 75 years of age, weighting 235.9 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, liver function test abnormal, multi-organ failure. Campath dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, RITUXIMAB. Patient was hospitalized. Patient died on 11/17/2007.


Campath Side Effects Report #5592776-5
Campath side effect was reported by a Health Professional from UNITED STATES on Dec 28, 2007. Male patient, 75 years of age, weighting 235.9 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, liver function test abnormal, multi-organ failure. Campath dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, RITUXIMAB. Patient was hospitalized. Patient died on 11/17/2007.

Campath Side Effects Report #5643393-X
Campath side effect was reported by a Health Professional from UNITED STATES on Feb 20, 2008. Male patient, 75 years of age, weighting 235.9 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, liver function test abnormal, multi-organ failure. Campath dosage: unknown. During the same period patient was treated with FLUDARABINE, RITUXIMAB. Patient was hospitalized. Patient died on 11/17/2007.

Campath Side Effects Report #5648298-6
Campath side effect was reported by a Health Professional from UNITED STATES on Feb 20, 2008. Male patient, 75 years of age, weighting 235.9 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, liver function test abnormal, multi-organ failure. Campath dosage: unknown. During the same period patient was treated with FLUDARABINE, RITUXIMAB. Patient was hospitalized. Patient died on 11/17/2007.

Campath Side Effects Report #5747418-2
Campath side effect was reported by a Health Professional from UNITED STATES on May 20, 2008. Male patient, 75 years of age, weighting 235.9 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, liver function test abnormal, multi-organ failure. Campath dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, RITUXIMAB. Patient was hospitalized. Patient died on 11/17/2007.

Campath Side Effects Report #5755329-1
Campath side effect was reported by a Health Professional from UNITED STATES on May 07, 2008. Male patient, 75 years of age, weighting 235.9 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, liver function test abnormal, multi-organ failure. Campath dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, RITUXIMAB. Patient was hospitalized. Patient died on 11/17/2007.


Campath Side Effects Report #5796257-5
Campath side effect was reported by a Health Professional from UNITED STATES on June 25, 2008. Male patient, 75 years of age, weighting 235.9 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , constipation , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, lipase increased. Campath dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, RITUXIMAB. Patient was hospitalized. Patient died on 11/17/2007.

Campath Side Effects Report #5809547-4
Campath side effect was reported by a Health Professional from UNITED STATES on July 07, 2008. Male patient, 75 years of age, weighting 235.9 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , constipation , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, lipase increased. Campath dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, RITUXIMAB. Patient was hospitalized. Patient died on 11/17/2007.

Campath Side Effects Report #5811474-3
Campath side effect was reported by a Health Professional from UNITED STATES on July 07, 2008. Male patient, 75 years of age, weighting 235.9 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , constipation , cytomegalovirus infection , diarrhoea, dyspnoea, graft versus host disease, hypotension, lipase increased. Campath dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, RITUXIMAB. Patient was hospitalized. Patient died on 11/17/2007.

Campath Side Effects Report #5751883-4
Campath side effect was reported by a Health Professional from UNITED STATES on May 20, 2008. Male patient, 66 years of age, weighting 198.4 lb, was diagnosed with chronic lymphocytic leukaemia, infection prophylaxis and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, acute respiratory distress syndrome, alanine aminotransferase increased, ascites, aspartate aminotransferase increased, atrial fibrillation , atrial flutter, blood bilirubin increased, blood creatinine increased. Campath dosage: unknown. During the same period patient was treated with FLUDARA, RITUXIMAB, DIPHENHYDRAMINE, ACETAMINOPHEN, COTRIM, ASPIRIN, PLAVIX, COLACE. Patient was hospitalized. Patient died on 04/19/2007.

Campath Side Effects Report #5798778-8
Campath side effect was reported by a Health Professional from UNITED STATES on June 25, 2008. Male patient, 66 years of age, weighting 198.4 lb, was diagnosed with chronic lymphocytic leukaemia, infection prophylaxis and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, acute respiratory distress syndrome, alanine aminotransferase increased, ascites, aspartate aminotransferase increased, atrial fibrillation , atrial flutter, blood bilirubin increased, blood creatinine increased. Campath dosage: unknown. During the same period patient was treated with FLUDARA, RITUXIMAB, DIPHENHYDRAMINE, ACETAMINOPHEN, ASPIRIN, PLAVIX, COLACE. Patient was hospitalized. Patient died on 04/19/2007.


Campath Side Effects Report #4594091-5
Campath side effect was reported by a Health Professional from on Feb 09, 2005. Male patient, 60 years of age, weighting 239.0 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, blood pressure increased, cerebrovascular accident, chills, feeling cold, loss of consciousness, oedema peripheral, respiratory arrest. Campath dosage: 3 MG, 1 DOSE, INTRAVENOUS. During the same period patient was treated with TYLENOL, BENADRYL, HYDROCHLOROZIDE, ATENOLOL, DOCUSATE, GANCICLOVIR, SELENIUM SULFIDE, SENNOSIDE A. Patient died on 05/20/2004.

Campath Side Effects Report #5916439-9
Campath side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 07, 2008. Male patient, 54 years of age, was diagnosed with chronic lymphocytic leukaemia, infection prophylaxis and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, ascites, cytomegalovirus test positive, hepatic enzyme increased, jaundice , nausea , pyrexia, urticaria. Campath dosage: TOTAL DAILY DOSE: 15 MG. During the same period patient was treated with BACTRIM, FAMVIR, BENADRYL, TYLENOL. Patient was hospitalized. Patient recovered.

Campath Side Effects Report #5839598-5
Campath side effect was reported by a Consumer or non-health professional from UNITED STATES on June 23, 2008. Male patient was diagnosed with chronic lymphocytic leukaemia, infection prophylaxis and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, cytomegalovirus test positive, hepatic enzyme increased, jaundice , nausea , urticaria. Campath dosage: TOTAL DAILY DOSE: 30 MG. During the same period patient was treated with BACTRIM, FAMVIR, BENADRYL, TYLENOL. Patient was hospitalized. Patient recovered.

Campath Side Effects Report #5518696-X
Campath side effect was reported by a Health Professional from UNITED STATES on Nov 06, 2007. Male patient, 65 years of age, weighting 198.0 lb, was diagnosed with infection prophylaxis and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, acute respiratory distress syndrome, alanine aminotransferase increased, ascites, aspartate aminotransferase increased, atrial fibrillation , atrial flutter, blood bilirubin increased, blood creatinine increased. Campath dosage: 3/10/30 MG TIWX6 WEEKS. During the same period patient was treated with FLUDARA, RITUXIMAB, DIPHENHYDRAMINE, ACETAMINOPHEN, COTRIM, ASPIRIN, PLAVIX, COLACE. Patient was hospitalized. Patient died on 04/19/2007.

Campath Side Effects Report #5523869-6
Campath side effect was reported by a Health Professional from UNITED STATES on Nov 09, 2007. Male patient, 65 years of age, weighting 198.0 lb, was diagnosed with infection prophylaxis and was treated with Campath. After drug was administered, patient experienced the following side effects: abdominal distension, acute respiratory distress syndrome, alanine aminotransferase increased, ascites, aspartate aminotransferase increased, atrial fibrillation , atrial flutter, blood bilirubin increased, blood creatinine increased. Campath dosage: 3/10/30 MG TIWX6 WEEKS. During the same period patient was treated with FLUDARA, RITUXIMAB, DIPHENHYDRAMINE, ACETAMINOPHEN, COTRIM, ASPIRIN, PLAVIX, COLACE. Patient was hospitalized. Patient died on 04/19/2007.