Busulfex and nausea Patient Reports February 13, 2012

Busulfex Side Effects Report #5819581-6
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 07, 2008. Female patient, child 9 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, anorexia, bone marrow transplant , condition aggravated, cystitis haemorrhagic, diarrhoea, malaise, nausea , stomatitis. Busulfex dosage: 11.1 ML, INTRAVENOUS, 14.8 ML DAILY DOSE; INTRAVENOUS, 3.7 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with CYTARABINE, MELPHALAN, ETOPOSIDE, VALPROATE, METHOTREXATE, TACROLIMIS. Patient died.

Busulfex Side Effects Report #5849766-4
Busulfex side effect was reported by a Health Professional from JAPAN on Aug 08, 2008. Male patient, child 9 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, gastritis, hypercalcaemia, infection , liver disorder, nausea , occult blood, venoocclusive liver disease. Busulfex dosage: 18.4 ML, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, PHENYTOIN, TACROLIMUS, METHOTREXATE. Patient recovered.

Busulfex Side Effects Report #5878638-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 28, 2008. Female patient, child 9 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, bone marrow transplant rejection, cystitis haemorrhagic, diarrhoea, hypokalaemia, malignant neoplasm progression, nausea , stomatitis. Busulfex dosage: 11.1 ML, INTRAVENOUS; 14.8 ML, DAILY DOSE; INTRAVENOUS; 3.7 ML, DAILY DOSE, INTRAVENOUS. During the same period patient was treated with CYTARABINE, MELPHALAN, ETOPOSIDE, VALPROATE, METHOTREXATE, TACROLIMUS. Patient died.

Busulfex Side Effects Report #5871281-2
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 19, 2008. Male patient, child 7 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, anorexia, bone marrow transplant , cystitis haemorrhagic, diarrhoea, malaise, nausea , sepsis , stomatitis. Busulfex dosage: 68 ML INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE, LENOGRASTIM, CYCLOSPORINE. Patient was hospitalized. Patient recovered.


Busulfex Side Effects Report #5819493-8
Busulfex side effect was reported by a Health Professional from JAPAN on July 08, 2008. Male patient, 69 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, graft versus host disease, jaundice cholestatic, malaise, nausea , stomatitis. Busulfex dosage: 30 ML INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHSOPHATE, VALPROATE, MELPHALAN, FILGRASTIM, TACTROLIMUS. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5743646-0
Busulfex side effect was reported by a Physician from JAPAN on May 08, 2008. Female patient, 67 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute respiratory failure, anorexia, cytomegalovirus viraemia, diarrhoea, enterobacter sepsis, malaise, nausea , renal failure acute, thrombocytopenia. Busulfex dosage: 24 ML. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, NEUPOGEN, METHOTREXATE, TACROLIMUS. Patient died.

Busulfex Side Effects Report #5818262-2
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 07, 2008. Male patient, 64 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: cystitis, diarrhoea, encephalitis viral, malaise, nausea , pneumonia , streptococcal sepsis. Busulfex dosage: 19.5 ML, DAILY DOSE INTRAVENOUS; 26 ML, DAILY DOSE; INTRAVENOUS; 6.5 ML, DAILY DOSE; INTRAVENOU. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, FILGRASTIM, TACROLIMUS, MYCOPHENOLATE MOFETIL. Patient recovered.

Busulfex Side Effects Report #5786817-X
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on June 09, 2008. Male patient, 63 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, graft versus host disease, headache , malaise, nausea , oedema, pain in extremity, pneumonia . Busulfex dosage: 30 ML. During the same period patient was treated with MELPHALAN, TACROLIMUS. Patient died.

Busulfex Side Effects Report #5878607-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 25, 2008. Male patient, 63 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, graft versus host disease, headache , malaise, nausea , oedema, pain in extremity, pneumonia . Busulfex dosage: 30 ML, DAILY DOSE INTRAVENOUS. During the same period patient was treated with MELPHALAN, TACROLIMUS. Patient died.


Busulfex Side Effects Report #5972679-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 13, 2008. Male patient, 63 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, graft versus host disease, headache , malaise, nausea , oedema, pain in extremity, pneumonia . Busulfex dosage: 30 ML, DAILY DOSE. During the same period patient was treated with MELPHALAN, TACROLIMUS. Patient died on 10/16/2007.

Busulfex Side Effects Report #5819491-4
Busulfex side effect was reported by a Health Professional from JAPAN on July 08, 2008. Male patient, 62 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, enterococcal sepsis, malaise, nausea , stomatitis, treatment failure. Busulfex dosage: 30 ML, INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, MELPHALAN, FILGRASTIM, TACROLIMUS, MYCOPHENOLATE MOFETIL. Patient recovered.

Busulfex Side Effects Report #5877275-5
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 27, 2008. Male patient, 62 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, enterococcal sepsis, leukaemia recurrent, malaise, nausea , stomatitis. Busulfex dosage: 30 ML, UNK, INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, MELPHALAN, FILGRASTIM, TACROLIMUS, MYCOPHENOLATE MOFETIL. Patient died on 05/15/2007.

Busulfex Side Effects Report #5743657-5
Busulfex side effect was reported by a Health Professional from JAPAN on May 08, 2008. Male patient, 60 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: adenoviral haemorrhagic cystitis, anorexia, bone marrow transplant , cytomegalovirus antigen positive, cytomegalovirus viraemia, graft versus host disease, liver disorder, nausea , nystagmus. Busulfex dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, NEUPOGEN, METHOTREXATE, TACROLIMUS. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5812208-9
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 01, 2008. Male patient, 60 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant rejection, catheter related infection, cytomegalovirus viraemia, diarrhoea, enterocolitis bacterial, nausea , stomatitis. Busulfex dosage: 31.48 ML, DAILY DOSE INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, PHENYTOIN, FILGRASTIM, METHOTREXATE, TACROLIMUS. Patient was hospitalized. Patient recovered.


Busulfex Side Effects Report #5894817-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Sept 11, 2008. Male patient, 59 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, aspergillosis, cytomegalovirus viraemia, diarrhoea, interstitial lung disease, malaise, nausea , oropharyngeal pain, pruritus. Busulfex dosage: 184 MG, DAILY DOSE INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYTARABINE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, FILGRASTIM. Patient died on 10/28/2007.

Busulfex Side Effects Report #5798835-6
Busulfex side effect was reported by a Health Professional from JAPAN on June 16, 2008. Male patient, 58 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia recurrent, anorexia, enterocolitis, febrile neutropenia, graft versus host disease, malaise, nausea , stomatitis. Busulfex dosage: 460 MG INTRAVENOUS. During the same period patient was treated with PHENYTOIN, NEUPOGEN, MITOXANTRONE HYDROCHLORIDE, METHOTREXATE, CYCLOSPORINE, MITOXANTRONE HYDROCHLORIDE. Patient died.

Busulfex Side Effects Report #5809438-9
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on June 27, 2008. Male patient, 58 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, cytomegalovirus colitis, diarrhoea, febrile neutropenia, malaise, nausea . Busulfex dosage: 15.2 ML, DAILY DOSE, INTRAVENOUS; 20 ML, DAILY DOSE; INTRAVENOUS; 40 ML; DAILY DOSE; INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE, NARTOGRASTIM, METHOTREXATE, CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5989584-X
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 21, 2008. Male patient, 58 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, anorexia, cytomegalovirus colitis, diarrhoea, febrile neutropenia, malaise, nausea , stem cell transplant. Busulfex dosage: 15.2 ML, DAILY DOSE. During the same period patient was treated with PREDNISOLONE, CYCLOPHOSPHAMIDE, VALPROATE, NARTOGRASTIM, CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5990196-2
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Dec 01, 2008. Male patient, 58 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia recurrent, anorexia, diarrhoea, enterocolitis viral, febrile neutropenia, graft versus host disease, malaise, nausea , stomatitis. Busulfex dosage: 460 MG. During the same period patient was treated with METHOTREXATE, MITOXANTRONE HYDROCHLORIDE, FLUDARABINE PHOSPHATE, PHENYTOIN, FILGRASTIM, CYCLOSPORINE. Patient died.


Busulfex Side Effects Report #6060141-2
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Jan 15, 2009. Male patient, 58 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia recurrent, anorexia, enterocolitis viral, febrile neutropenia, graft versus host disease, malaise, nausea , stomatitis. Busulfex dosage: 460 MG, INTRAVENOUS. During the same period patient was treated with METHOTREXATE, CYCLOSPORINE, MITOXANTRONE HYDROCHLORIDE, FLUDARABINE PHOSPHATE, PHENYTOIN, FILGRASTIM. Patient died on 11/18/2007.

Busulfex Side Effects Report #5782929-5
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on June 11, 2008. Female patient, 57 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant , malaise, nausea , sepsis . Busulfex dosage: 30 ML, INTRAVENOUS. During the same period patient was treated with MELPHALAN. Patient died on 07/19/2006.

Busulfex Side Effects Report #5872400-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 20, 2008. Female patient, 57 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia recurrent, anorexia, bone marrow transplant , diarrhoea, febrile neutropenia, malaise, nausea , reticulocyte count decreased, stomatitis. Busulfex dosage: 30 ML, INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, LENOGRASTIM, METHOTREXATE, CYCLOSPORINE. Patient died.

Busulfex Side Effects Report #5893737-9
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Sept 04, 2008. Female patient, 57 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, anorexia, candida sepsis, cytomegalovirus viraemia, disseminated intravascular coagulation, histiocytosis haematophagic, nausea , stem cell transplant, stomatitis. Busulfex dosage: 160 MG, DAILY DOSE INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, ANTITHYMOCYTE IMMUNOGLOBULIN, CYCLOSPORINE, METHOTREXATE, LEUCOVORIN CALCIUM, FILGRASTIM. Patient recovered.

Busulfex Side Effects Report #5955102-5
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Oct 30, 2008. Female patient, 57 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, anorexia, candida sepsis, cytomegalovirus viraemia, disseminated intravascular coagulation, histiocytosis haematophagic, nausea , stem cell transplant, stomatitis. Busulfex dosage: 160 MG, DAILY DOSE INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, THYMOGLOBULIN, CYCLOSPORINE, FILGRASTIM, METHOTREXATE, LEUCOVORIN CALCIUM. Patient died.


Busulfex Side Effects Report #5698189-X
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Mar 21, 2008. Male patient, 56 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, blood bilirubin increased, blood urea increased, encephalitis herpes, gamma-glutamyltransferase increased, nausea , sepsis . Busulfex dosage: 20.1 ML INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE. Patient was hospitalized. Patient died.

Busulfex Side Effects Report #5744162-2
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on May 08, 2008. Female patient, 55 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, alanine aminotransferase increased, anorexia, blood bilirubin increased, bone marrow transplant , bone marrow transplant rejection, gastrointestinal haemorrhage, nausea , platelet count decreased. Busulfex dosage: 30 ML, INTRAVENOUS. Patient was hospitalized. Patient died.

Busulfex Side Effects Report #5877535-8
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 26, 2008. Female patient, 55 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, blood potassium decreased, blood sodium decreased, bone marrow transplant rejection, malaise, nausea , transplant failure. Busulfex dosage: 192 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, PHENYTOIN, FILGRASTIM, METHOTREXATE, CYCLOSPORINE. Patient recovered.

Busulfex Side Effects Report #5877537-1
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 25, 2008. Male patient, 55 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, adenoviral haemorrhagic cystitis, constipation , diabetes insipidus , dyspnoea, malaise, nausea , pyrexia, stomatitis. Busulfex dosage: 30 ML, DAILY DOSE INTRAVENOUS. During the same period patient was treated with ANTITHYMOCYTE IMMUNOGLOBULIN, MELPHALAN, TACROLIMUS. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #6026260-1
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Dec 18, 2008. Male patient, 55 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, adenoviral haemorrhagic cystitis, asthma , constipation , diabetes insipidus , malaise, myocarditis, nausea , stomatitis. Busulfex dosage: 30 ML, DAILY DOSE. During the same period patient was treated with ANTITHYMOCYTE IMMUNOGLOBULIM, MELPHALAN, TACROLIMUS. Patient was hospitalized. Patient died on 05/29/2008.


Busulfex Side Effects Report #6072885-7
Busulfex side effect was reported by a Health Professional from JAPAN on Jan 23, 2009. Male patient, 55 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, adenoviral haemorrhagic cystitis, asthma , cardiotoxicity, constipation , diabetes insipidus , myocarditis, nausea , stem cell transplant. Busulfex dosage: 30 ML, DAILY DOSE. During the same period patient was treated with IDARUBICIN HYDROCHLORIDE, MITOXANTRONE HYDROCHLORIDE, DAUNORUBICIN HYDROCHLORIDE, ACLARUBICIN HYDROCHLORIDE, ANTITHYMOCYTE IMMUNOGLOBULIN, MELPHALAN, TACROLIMUS. Patient was hospitalized. Patient died on 05/29/2008.

Busulfex Side Effects Report #5809452-3
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on June 23, 2008. Male patient, 53 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, malaise, malignant neoplasm progression, nausea , pneumonia , staphylococcal sepsis, stem cell transplant, stomatitis. Busulfex dosage: 7.5 ML, INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, NEUPOGEN, METHOTREXATE, CYCLOSPORINE. Patient died on 08/15/2007.

Busulfex Side Effects Report #5886250-6
Busulfex side effect was reported by a Health Professional from JAPAN on Sept 01, 2008. Male patient, 53 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, acute myeloid leukaemia recurrent, anorexia, bone marrow transplant , diarrhoea, headache , malaise, nausea , pain in extremity. Busulfex dosage: 12 ML, INTRAVENOUS; 24 ML, DAILY: INTRAVENOUS; DAILY DOSE; INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, PHENYTOIN, METHOTREXATE, TACROLIMUS. Patient recovered.

Busulfex Side Effects Report #5893733-1
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Sept 05, 2008. Female patient, 53 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, anorexia, diarrhoea, hyperglycaemia, klebsiella sepsis, liver disorder, malaise, nausea , pneumonia klebsiella. Busulfex dosage: 27.2 ML, INTRAVENOUS. During the same period patient was treated with CYCLOSPORINE, FLUDARABINE PHOSPHATE, VALPROATE, NARTOGRASTIM, METHOTREXATE, METHYLPREDNISOLONE. Patient died.

Busulfex Side Effects Report #5955110-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Oct 30, 2008. Male patient, 53 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: cytomegalovirus viraemia, diarrhoea, febrile neutropenia, hepatic function abnormal, hyperkalaemia, hyponatraemia, nausea , renal impairment, stomatitis. Busulfex dosage: 8 ML, TID INTRAVENOUS; 8 ML, QID; INTRACAVERNOUS; 8 ML, QD; INTRAVENOUS. During the same period patient was treated with DEPAKENE, CYCLOPHOSPHAMIDE, NEUTROGIN, METHOTREXATE, CYCLOSPORINE. Patient was hospitalized. Patient recovered.


Busulfex Side Effects Report #5729830-0
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Apr 21, 2008. Female patient, 52 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: adenoviral haemorrhagic cystitis, anorexia, blood potassium decreased, engraft failure, malaise, nausea , pharyngeal oedema, pneumonia bacterial, pulmonary haemorrhage. Busulfex dosage: 26.8 ML, INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYTARABINE, MITOXANTRONE, PHENYTOIN, NEUPOGEN, METHOTREXATE, TACROLIMUS. Patient died.

Busulfex Side Effects Report #5984857-9
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 18, 2008. Female patient, 52 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: adult t-cell lymphoma/leukaemia recurrent, anorexia, bone marrow transplant , cytomegalovirus viraemia, diarrhoea, hypokalaemia, malaise, nausea . Busulfex dosage: 6.4 ML, QD. During the same period patient was treated with DEPAKENE, FLUDARABINE PHOSPHATE, FILGRASTIM. Patient recovered.

Busulfex Side Effects Report #5819606-8
Busulfex side effect was reported by a Health Professional from JAPAN on July 08, 2008. Male patient, 51 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, cystitis haemorrhagic, diarrhoea, malaise, malignant neoplasm progression, nausea , stem cell transplant, stomatitis. Busulfex dosage: 24 ML, DAILY DOSE INTRAVENOUS; 32 ML, DAILY DOSE; INTRAVENOUS; 8 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE, FILGRASTIM, METHOTREXATE, CYCLOSPORINE. Patient was hospitalized. Patient died on 08/26/2007.

Busulfex Side Effects Report #5818265-8
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 07, 2008. Male patient, 50 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bacterial sepsis, diarrhoea, enterococcal sepsis, nausea , stomatitis. Busulfex dosage: 153 MG, DAILY DOSE, INTRAVENOUS ; 204 MG, DAILY DOSE; INTRAVENOUS; 51 MG, DAILY DOSE; INTRAVENO. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE, METHOTREXATE, TACROLIMUS. Patient recovered.

Busulfex Side Effects Report #5883704-3
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 29, 2008. Male patient, 50 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia recurrent, anorexia, diarrhoea, hiccups, malaise, nausea , neutropenia, oedema, rash . Busulfex dosage: 24.6 ML, INTRAVENOUS; 32.8 ML, DAILY DOSE; INTRAVENOUS; 8.2 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with CYTARABINE, VALPROATE, CYCLOPHOSPHAMIDE, NARTOGRASTIM, METHOTREXATE, TACROLIMUS. Patient was hospitalized. Patient recovered.


Busulfex Side Effects Report #5894819-8
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Sept 11, 2008. Male patient, 50 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: bacterial sepsis, bone marrow transplant rejection, diarrhoea, enterococcal sepsis, nausea , stomatitis. Busulfex dosage: 153 MG, DAILY DOSE INTRAVENOUS; 204 MG, DAILY DOSE; INTRAVENOUS; 51 MG, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE, METHOTREXATE, TACROLIMUS. Patient recovered.

Busulfex Side Effects Report #5958872-5
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 04, 2008. Male patient, 50 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia recurrent, anorexia, cytomegalovirus viraemia, diarrhoea, hiccups, malaise, nausea , neutropenia, oedema. Busulfex dosage: 8.2 ML, TID INTRAVENOUS; 8.2 ML, QID; INTRAVENOUS; 8.2 ML, QD; INTRAVENOUS. During the same period patient was treated with CYTARABINE, VALPROATE, CYCLOPHOSPHAMIDE, NARTOGRASTIM, METHOTREXATE, TACROLIMUS. Patient was hospitalized and became disabled. Patient died.

Busulfex Side Effects Report #6016185-X
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Dec 09, 2008. Male patient, 50 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia recurrent, bone marrow transplant , cytomegalovirus viraemia, diarrhoea, hiccups, nausea , neutropenia, oedema, rash . Busulfex dosage: 8.2 ML, TID INTRAVENOUS : 8.2 ML,QID; INTRAVENOUS : 8.2 ML,QD;INTRAVENOUS. During the same period patient was treated with CYTARABINE, VALPROATE, CYCLOPHOSPHAMIDE, NARTOGRASTIM, TACROLIMUS. Patient was hospitalized and became disabled. Patient recovered.

Busulfex Side Effects Report #5819591-9
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 07, 2008. Male patient, 49 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, graft versus host disease, jaundice , malaise, nausea , stomatitis. Busulfex dosage: 24 ML; 32 ML, DAILY DOSE; INTRAVENOUS; 8 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, FILGRASTIM, CYCLOSPORINE. Patient recovered.

Busulfex Side Effects Report #5886249-X
Busulfex side effect was reported by a Health Professional from JAPAN on Sept 03, 2008. Female patient, 48 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant rejection, diarrhoea, febrile neutropenia, gastrointestinal haemorrhage, graft versus host disease, malaise, nausea , renal disorder. Busulfex dosage: 27.72ML INTRAVENOUS. During the same period patient was treated with GANCICLOVIR, FLUDARABINE PHOSPHATE, VALPROATE, LENOGRASTIM, METHOTREXATE, TACROLIMUS. Patient was hospitalized. Patient died.

Busulfex Side Effects Report #5809439-0
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on June 27, 2008. Male patient, 47 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anorexia, bone marrow transplant rejection, liver disorder, liver function test abnormal, nausea , platelet count decreased, pneumonia . Busulfex dosage: unknown. During the same period patient was treated with NEUPOGEN, METHOTREXATE, CYCLOSPORINE, FLUDARABINE PHOSPHATE, PHENYTOIN. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5819511-7
Busulfex side effect was reported by a Health Professional from JAPAN on July 08, 2008. Female patient, 47 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant , diarrhoea, gastrointestinal haemorrhage, malaise, multi-organ failure, nausea . Busulfex dosage: 6 ML INTRAVENOUS; 24 ML, DAILY DOSE; INTRAVENOUS; 18 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE, NARTOGRASTIM, METHOTREXATE, TACROLIMUS. Patient died.

Busulfex Side Effects Report #5979847-6
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 18, 2008. Female patient, 47 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, ascites, diarrhoea, gastrointestinal haemorrhage, malaise, multi-organ failure, nausea . Busulfex dosage: 6 ML, DAILY DOSE, INTRAVENOUS; 6 ML, QID, INTRAVENOUS; 6 ML, TID, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE, NARTOGRASTIM, METHOTREXATE, TACROLIMUS. Patient died.

Busulfex Side Effects Report #6076410-6
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Jan 27, 2009. Female patient, 47 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, ascites, diarrhoea, gastrointestinal haemorrhage, malaise, multi-organ failure, nausea . Busulfex dosage: 6 ML, DAILY DOSE INTRAVENOUS ; 6 ML, QID, INTRAVENOUS ; 6 ML, TID, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE, NARTOGRASTIM, METHOTREXATE, TACROLIMUS. Patient died on 07/03/2007.

Busulfex Side Effects Report #5822823-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 14, 2008. Male patient, 46 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia recurrent, anorexia, convulsion, diarrhoea, graft versus host disease, malaise, nausea , staphylococcal sepsis, stomatitis. Busulfex dosage: 27 ML, INTRAVENOUS, 36 ML DAILY DOSE; INTRAVENOUS, 9 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, LENOGRASTIM, TACROLIMUS, CYTARABINE. Patient was hospitalized. Patient died on 08/29/2007.


Busulfex Side Effects Report #5862345-8
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 12, 2008. Male patient, 46 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, anorexia, diarrhoea, enterocolitis, hyponatraemia, malaise, nausea , renal failure acute, stomatitis. Busulfex dosage: 40 ML. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, METHOTREXATE, TACROLIMUS. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5920081-3
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Sept 30, 2008. Male patient, 46 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant rejection, cytomegalovirus infection , gastrointestinal ulcer, gastrointestinal ulcer haemorrhage, liver function test abnormal, malaise, nausea , stem cell transplant. Busulfex dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, ETOPOSIDE, PHENYTOIN, FILGRASTIM, METHOTREXATE, CYCLOSPORINE. Patient died on 12/08/2006.

Busulfex Side Effects Report #5798834-4
Busulfex side effect was reported by a Health Professional from JAPAN on June 16, 2008. Female patient, 45 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, leukaemia recurrent, leukocytosis, malaise, nausea , oral disorder. Busulfex dosage: 5.3 ML INTRAVENOUS; 21.2 ML, DAILY DOSE; INTRAVENOUS; 15.9 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE, NEUPOGEN, METHOTREXATE, TACROLIMUS. Patient died on 04/14/2007.

Busulfex Side Effects Report #5878609-8
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 25, 2008. Female patient, 44 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, constipation , diarrhoea, encephalitis viral, jaundice , malaise, nausea , oropharyngeal pain, pruritus. Busulfex dosage: 26.8 ML, DAILY DOSE INTRAVENOUS. During the same period patient was treated with MELPHALAN, TACROLIMUS. Patient died.

Busulfex Side Effects Report #5979833-6
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 13, 2008. Female patient, 44 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: abdominal discomfort, anorexia, constipation , diarrhoea, encephalitis herpes, jaundice , malaise, nausea , oropharyngeal pain. Busulfex dosage: 26.8 ML, DAILY DOSE, INTRAVENOUS. During the same period patient was treated with MELPHALAN, TACROLIMUS. Patient died on 11/10/2007.

Busulfex Side Effects Report #5767005-X
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on May 27, 2008. Male patient, 42 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, cytomegalovirus viraemia, diarrhoea, encephalitis viral, febrile neutropenia, graft versus host disease, human herpesvirus 6 infection, nausea , sepsis . Busulfex dosage: 36 ML. During the same period patient was treated with PHENYTOIN, NEUPOGEN, METHOTREXATE, TACROLIMUS, PREDNISOLONE, CYCLOPHOSPHAMIDE. Patient was hospitalized and became disabled. Patient recovered.

Busulfex Side Effects Report #5819426-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 08, 2008. Male patient, 42 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia recurrent, nausea , sepsis , stomatitis. Busulfex dosage: 150 ML, INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, TACROLIMUS. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #6016160-5
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Dec 09, 2008. Male patient, 42 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: nausea , sepsis , stomatitis. Busulfex dosage: 150 ML INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, TACROLIMUS. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5921366-7
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Oct 01, 2008. Female patient, 41 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, cytomegalovirus antibody positive, malaise, nausea , pneumonia cytomegaloviral, respiratory failure, stomatitis. Busulfex dosage: 3.2 MG, INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYTARABINE, CYCLOSPORINE, CELLCEPT USA, NEUTROGIN. Patient died.

Busulfex Side Effects Report #6060138-2
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Jan 16, 2009. Female patient, 41 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, blood potassium decreased, blood potassium increased, cytomegalovirus antigen positive, disseminated intravascular coagulation, malaise, nausea , pneumonia cytomegaloviral, respiratory failure. Busulfex dosage: 3.2 MG, INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYTARABINE, CYCLOSPORINE, CELLCEPT USA, NEUTROGIN. Patient was hospitalized. Patient died on 06/30/2007.


Busulfex Side Effects Report #5819595-6
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 07, 2008. Female patient, 36 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bacterial sepsis, diarrhoea, enterobacter sepsis, malaise, nausea , pneumonia viral, stomatitis. Busulfex dosage: 165 ML, DAILY DOSE; 220 ML, DAILY DOSE; INTRAVENOUS; 55 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, MELPHALAN, FILGRASTIM, TACROLIMUS. Patient died.

Busulfex Side Effects Report #6015344-X
Busulfex side effect was reported by a Health Professional from JAPAN on Dec 09, 2008. Male patient, 34 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant rejection, malaise, nausea , pharyngitis. Busulfex dosage: 6.67 ML QID. During the same period patient was treated with ENDOXAN NET, DEPAKENE, FILGRASTIM, METHOTREXATE, TACROLIMUS. Patient recovered.

Busulfex Side Effects Report #5947667-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Oct 29, 2007. Male patient, 33 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant rejection, diarrhoea, malaise, nausea , pneumonia staphylococcal, staphylococcal infection , stenotrophomonas sepsis, stomatitis. Busulfex dosage: 6 ML, QID, INTRAVENOUS. During the same period patient was treated with VALPROATE, FLUDARABINE PHOSPHATE, LENOGRASTIM, METHOTREXATE, TACROLIMUS. Patient was hospitalized. Patient died on 04/22/2007.

Busulfex Side Effects Report #5906671-2
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Sept 19, 2008. Female patient, 31 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute lymphocytic leukaemia recurrent, bone marrow transplant , diarrhoea, nausea , stomatitis. Busulfex dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, LENOGRASTIM, METHOTREXATE, TACROLIMUS. Patient recovered.

Busulfex Side Effects Report #5819490-2
Busulfex side effect was reported by a Health Professional from JAPAN on July 08, 2008. Female patient, 28 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, anorexia, condition aggravated, diarrhoea, febrile neutropenia, malaise, nausea , stomatitis. Busulfex dosage: 21.6 ML, INTRAVENOUS; 28.8 ML, DAILY DOSE; INTRAVENOUS; 7.2 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, PHENYTOIN, FILGRASTIM, CYCLOSPORINE, MYCOPHENOLATE MOFETIL. Patient died on 09/02/2007.

Busulfex Side Effects Report #6053854-X
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Jan 16, 2009. Male patient, 24 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: nausea , pneumonia staphylococcal. Busulfex dosage: 0.8 MG/KG, QID INTRAVENOUS. During the same period patient was treated with CYTARABINE, CYCLOPHOSPHAMIDE, VALPROATE, NIMUSTINE, MESNA, CYCLOSPORINE, FILGRASTIM. Patient died on 11/27/2006.

Busulfex Side Effects Report #5834903-8
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 24, 2008. Female patient, 22 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, anorexia, diarrhoea, encephalitis viral, gamma-glutamyltransferase increased, malaise, nausea , pigmentation disorder, stomatitis. Busulfex dosage: 15 ML, INTRAVENOUS; 20 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, MELPHALAN, VALPROATE, LENOGRASTIM, TACROLIMUS, SULFAMETHOXAZOLETRIMETHOPRIM. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5743652-6
Busulfex side effect was reported by a Health Professional from JAPAN on May 08, 2008. Male patient, 20 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, gamma-glutamyltransferase increased, malaise, nausea . Busulfex dosage: 80 MG; 160 MG; 160 MG. During the same period patient was treated with MELPHALAN, PHENYTOIN, LENOGRASTIM. Patient was hospitalized and became disabled. Patient recovered.

Busulfex Side Effects Report #5972682-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 12, 2008. Male patient, 20 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, blood bilirubin increased, blood potassium decreased, gamma-glutamyltransferase increased, malaise, nausea , stem cell transplant. Busulfex dosage: 40 MG, BID. During the same period patient was treated with MELPHALAN, PHENYTOIN, LENOGRASTIM. Patient was hospitalized and became disabled. Patient recovered.

Busulfex Side Effects Report #5800895-0
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on June 20, 2008. Female patient, child 2 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, enterococcal sepsis, malaise, nausea , stomatitis. Busulfex dosage: 10 ML, DAILY DOSE. During the same period patient was treated with MELPHALAN, CLONAZEPAM, NEUPOGEN, METHOTREXATE, CYCLOSPORINE. Patient recovered.


Busulfex Side Effects Report #5869635-3
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 18, 2008. Female patient, child 2 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, enterococcal sepsis, malaise, nausea , platelet count decreased, stomatitis. Busulfex dosage: 10 ML, DAILY DOSE INTRAVENOUS. During the same period patient was treated with GEMTUZUMAB, MELPHALAN, CLONAZEPAM, FILGRASTIM, METHOTREXATE, CYCLOSPORINE. Patient recovered.

Busulfex Side Effects Report #5933574-X
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Oct 14, 2008. Female patient, child 2 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, enterococcal sepsis, hyponatraemia, nausea , platelet count decreased, stomatitis. Busulfex dosage: 10 ML, DAILY DOSE, INTRAVENOUS. During the same period patient was treated with GEMTUZUMAB OZOGAMICIN, MELPHALAN, CLONAZEPAM, FILGRASTIM, METHOTREXATE, CYCLOSPORINE. Patient recovered.

Busulfex Side Effects Report #5769155-0
Busulfex side effect was reported by a Health Professional from JAPAN on May 29, 2008. Female patient, 18 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, malaise, nausea . Busulfex dosage: 13.2 ML, INTRAVENOUS. During the same period patient was treated with AMRUBICIN HYDROCHLORIDE, FLUDARABINE PHOSPHATE, VALPROATE, LENOGRASTIM, METHOTREXATE, CYCLOSPORINE. Patient recovered.

Busulfex Side Effects Report #5698124-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Mar 21, 2008. Male patient, 17 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: ascites, bacterial sepsis, blood bilirubin increased, gastrointestinal oedema, haematemesis, haematoma, nausea , oesophageal haemorrhage. Busulfex dosage: unknown. Patient died.

Busulfex Side Effects Report #5782932-5
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on June 11, 2008. Male patient, 17 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant , diarrhoea, malaise, nausea , sepsis , stomatitis. Busulfex dosage: 40 ML, INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, LENOGRASTIM, METHOTREXATE, TACROLIMUS. Patient recovered.

Busulfex Side Effects Report #5803066-7
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on June 23, 2008. Male patient, 16 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, blood lactate dehydrogenase increased, diarrhoea, hepatic enzyme increased, malaise, nausea , sepsis . Busulfex dosage: 20.1 ML; INTRAVENOUS; 26.8 ML, DAILY DOSE; INTRAVENOUS; 6.7 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, PHENYTOIN, NEUPOGEN, METHOTREXATE, TACROLIMUS. Patient recovered.

Busulfex Side Effects Report #5920078-3
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Sept 29, 2008. Male patient, 16 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant , diarrhoea, hyperglycaemia, liver disorder, nausea , sepsis , sialoadenitis, stomatitis. Busulfex dosage: unknown. During the same period patient was treated with ALKERAN, VALPROATE, NEUTROGIN, METHOTREXATE, TACROLIMUS. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5811842-X
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 01, 2008. Male patient, 15 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, anorexia, cardiac failure, cardiotoxicity, nausea , renal failure. Busulfex dosage: 14.4 ML, DAILY DOSE INTRAVENOUS; 19.2 ML, DAILY DOSE; INTRAVENOUS; 4.8 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with FILGRASTIM, PHENYTOIN, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5819420-3
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 08, 2008. Female patient, child 12 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, cellulitis , malaise, nail infection, nausea , pseudomonas infection, staphylococcal sepsis, stomatitis. Busulfex dosage: 14.1 ML, INTRAVENOUS; 18.8 ML, DAILY DOSE; INTRAVENOUS; 4.7 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with ETOPOSIDE, FLUDARABINE PHOSPHATE, VALPROATE, LENOGRASTIM, METHOTREXATE, TACROLIMUS. Patient recovered.

Busulfex Side Effects Report #5819425-2
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on July 08, 2008. Female patient, child 12 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, dry mouth, epistaxis, haematuria, malaise, nausea , staphylococcal sepsis, stem cell transplant. Busulfex dosage: 18 ML, INTRAVENOUS. During the same period patient was treated with THIOTEPA, MELPHALAN, PHENYTOIN, LENOGRASTIM. Patient was hospitalized. Patient recovered.


Busulfex Side Effects Report #5878642-6
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Aug 26, 2008. Female patient, child 12 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute graft versus host disease, anorexia, bone marrow transplant , clostridial infection, diarrhoea, malaise, nausea , rhabdomyosarcoma recurrent, stomatitis. Busulfex dosage: 9 ML, DAILY DOSE INTRAVENOUS; 18 ML, DAILY DOSE; INTRAVENOUS; DF, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with MELPHALAN, PHENYTOIN, FILGRASTIM, CYCLOSPORINE, METHYLPREDNISOLONE. Patient recovered.

Busulfex Side Effects Report #5893534-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Sept 08, 2008. Female patient, child 12 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: bone marrow transplant rejection, diarrhoea, dry mouth, epistaxis, haematuria, malaise, mucous membrane disorder, nausea , staphylococcal sepsis. Busulfex dosage: 18 ML, INTRAVENOUS. During the same period patient was treated with THIOTEPA, MELPHALAN, PHENYTOIN, LENOGRASTIM. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5979834-8
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 14, 2008. Female patient, child 12 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute lymphocytic leukaemia recurrent, anorexia, cellulitis , hepatic function abnormal, hypokalaemia, malaise, nail infection, nausea , staphylococcal sepsis. Busulfex dosage: 4.7 ML, TID, INTRAVENOUS, 4.7 ML, QID; INTRAVENOUS, 4.7 ML, QID; INTRAVENOUS. During the same period patient was treated with ETOPOSIDE, FLUDARABINE PHOSPHATE, VALPROATE, LENOGRASTIM, METHOTREXATE, TACROLUMIS. Patient recovered.

Busulfex Side Effects Report #5979846-4
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 14, 2008. Male patient, child 11 years of age, was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant rejection, diarrhoea, hypokalaemia, nausea , polyomavirus-associated nephropathy, stomatitis, thrombocytopenia, venoocclusive liver disease. Busulfex dosage: 5.2 ML, TID, INTRAVENOUS; 5.2 ML, QID, INTRAVENOUS; 5.2 ML, QD, INTRAVENOUS. During the same period patient was treated with DEPAKENE, MELPHALAN, NEUTROGIN, METHOTREXATE, TACROLIMUS. Patient was hospitalized. Patient recovered.

Busulfex Side Effects Report #5803069-2
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on June 23, 2008. Female patient was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute lymphocytic leukaemia recurrent, anorexia, convulsion, diarrhoea, graft versus host disease, nausea , respiratory disorder, stomatitis, venoocclusive liver disease. Busulfex dosage: unknown. During the same period patient was treated with ETOPOSIDE, CYCLOPHOSPHAMIDE, CLONAZEPAM, NEUPOGEN, METHOTREXATE, TACROLIMUS. Patient recovered.

Busulfex Side Effects Report #5803070-9
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on June 23, 2008. Female patient was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute lymphocytic leukaemia recurrent, anorexia, diarrhoea, malaise, nausea , stomatitis. Busulfex dosage: 3.9 ML, INTRAVENOUS; 5.2 ML, DAILY DOSE; INTRAVENOUS; 1.3 ML, DAILY DOSE; INTRAVENOUS. During the same period patient was treated with ETOPOSIDE, CYCLOPHOSPHAMIDE, CLONZEPAM, LENOGRASTIM, METHOTREXATE, CYCLOSPORINE. Patient recovered.

Busulfex Side Effects Report #5989260-3
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 25, 2008. Female patient was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute lymphocytic leukaemia recurrent, bone marrow transplant , nausea , neutropenia, pyrexia, respiratory disorder, sepsis , stomatitis, venoocclusive liver disease. Busulfex dosage: 2.4 ML, INTRAVENOUS. During the same period patient was treated with CLONAZEPAM, ZONISAMIDE, ETOPOSIDE, CYCLOPHOSPHAMIDE, FILGRASTIM, METHOTREXATE, TACROLIMUS. Patient recovered.

Busulfex Side Effects Report #5990193-7
Busulfex side effect was reported by a Consumer or non-health professional from JAPAN on Nov 25, 2008. Female patient was diagnosed with stem cell transplant and was treated with Busulfex. After drug was administered, patient experienced the following side effects: acute lymphocytic leukaemia recurrent, nausea , neutropenia, pyrexia, respiratory disorder, sepsis , stomatitis, venoocclusive liver disease. Busulfex dosage: 2.4 ML. During the same period patient was treated with CLONAZEPAM, ZONISAMIDE, ETOPOSIDE, CYCLOPHOSPHAMIDE, FILGRASTIM, METHOTREXATE, TACROLIMUS. Patient recovered.