Busulfan and staphylococcal sepsis 
Busulfan and staphylococcal sepsis Patient Reports February 12, 2012
Busulfan Side Effects Report #5422196-5
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Aug 03, 2007. Female patient, child 7 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: bone marrow transplant rejection, bronchopulmonary aspergillosis, cystitis haemorrhagic, erythema, flushing, pigmentation disorder, staphylococcal sepsis, swelling, venoocclusive liver disease. Busulfan dosage: 20 MG/KG; QD; IV. During the same period patient was treated with CYCLOPHOSPHAMIDE, ETOPOSIDE, VALPROATE, METHOTREXATE, TACROLIMUS. Patient recovered.
Busulfan Side Effects Report #5324436-X
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Apr 25, 2007. Male patient, 60 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: blood bilirubin increased, blood glucose increased, mouth haemorrhage, staphylococcal sepsis, stomatitis. Busulfan dosage: unknown. During the same period patient was treated with CYTARABINE, VALPROATE, FILGRASTIM, ETOPOSIDE. Patient recovered.
Busulfan Side Effects Report #5523815-5
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Nov 05, 2007. Male patient, 60 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: anorexia, nausea
, nystagmus, staphylococcal sepsis, vertigo. Busulfan dosage: 3.2 ML; QD; IV. During the same period patient was treated with FLUDARABINE PHOSPHATE, NEUPOGEN, METHOTREXATE, TACROLIMUS. Patient was hospitalized. Patient recovered.Busulfan Side Effects Report #5608395-8
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Jan 11, 2008. Male patient, 53 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: anorexia, malaise, nausea
, off label use, pneumonia , staphylococcal sepsis, stomatitis. Busulfan dosage: 7.5 MG;X1;IV. During the same period patient was treated with VALPROATE, FLUDARABINE PHOSPHATE. Patient died on 08/15/2007.Busulfan Side Effects Report #5496980-6
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Oct 09, 2007. Female patient, 52 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant
, diarrhoea, enterococcal sepsis, nausea , pathogen resistance, respiratory failure, staphylococcal sepsis, stomatitis. Busulfan dosage: 26.8 ML; X1; IV. During the same period patient was treated with FLUDARABINE PHOSPHATE. Patient was hospitalized and became disabled. Patient died on 08/11/2007.Busulfan Side Effects Report #5564611-2
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Dec 03, 2007. Female patient, 52 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: cardiac failure, enteritis, hepatic congestion, no therapeutic response, peritonitis, pseudomembranous colitis, staphylococcal sepsis, weight increased. Busulfan dosage: 12 ML; QD; IV; 24 ML; QD; IV. Patient recovered.
Busulfan Side Effects Report #5503592-4
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Oct 15, 2007. Male patient, 51 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: staphylococcal sepsis, supraventricular tachycardia, venoocclusive liver disease. Busulfan dosage: 30 ML;QD;IV. During the same period patient was treated with CYCLOPHOSPHAMIDE, VALPROATE, NEUPOGEN, METHOTREXATE, TACROLIMUS. Patient recovered.
Busulfan Side Effects Report #5468658-6
Busulfan side effect was reported by a Health Professional from JAPAN on Sept 11, 2007. Male patient, 50 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: bone marrow transplant
, oedema, staphylococcal sepsis. Busulfan dosage: 24.6 ML; QD; IV; 32.8 ML;QD;IV; 8.2 ML;QD;IV. During the same period patient was treated with CYTARABINE, VALPROATE, CYCLOPHOSPHAMIDE, NARTOGRASTIM, METHOTREXATE, TACROLIMUS. Patient was hospitalized. Patient recovered.Busulfan Side Effects Report #5332528-4
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on May 07, 2007. Male patient, 47 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: anorexia, cardiac failure, liver disorder, malaise, renal disorder, sepsis
, staphylococcal sepsis, stem cell transplant, stomatitis. Busulfan dosage: 4 MG; QID; IV. During the same period patient was treated with MELPHALAN, CLADRIBINE, PHENYTOIN, LENOGRASTIM, CIDLOSPORIN. Patient recovered.Busulfan Side Effects Report #5352384-8
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on May 24, 2007. Male patient, 47 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: cardiac failure, liver disorder, renal disorder, staphylococcal sepsis, stomatitis. Busulfan dosage: 4 ML; QID; IV. During the same period patient was treated with MELPHALAN, CLADRIBINE, PHENYTOIN, LENOGRASTIM, CYCLOSPORINE. Patient recovered.
Busulfan Side Effects Report #5391627-1
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on July 02, 2007. Male patient, 47 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: cardiac failure, liver disorder, renal disorder, staphylococcal sepsis, stomatitis, transplant failure. Busulfan dosage: 4 ML; QID; IV. During the same period patient was treated with MELPHALAN, CLADRIBINE, PHENYTOIN, LENOGRASTIM, CYCLOSPORINE, METHOTREXATE. Patient recovered.
Busulfan Side Effects Report #5663404-5
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Feb 22, 2008. Male patient, 46 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: acute graft versus host disease, acute myeloid leukaemia recurrent, anorexia, convulsion, diarrhoea, nausea
, staphylococcal sepsis, stomatitis. Busulfan dosage: 27 ML; 36 ML; 9 ML. Patient was hospitalized. Patient died.Busulfan Side Effects Report #5586034-2
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Dec 21, 2007. Female patient, 40 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: acinetobacter infection, acute graft versus host disease, bacterial sepsis, cystitis haemorrhagic, cytomegalovirus viraemia, liver disorder, pseudomembranous colitis, staphylococcal sepsis, stomatitis. Busulfan dosage: 31.2 ML; X1; IV. During the same period patient was treated with FLUDARABINE PHOSPHATE, PHENYTOIN. Patient was hospitalized and became disabled. Patient recovered.
Busulfan Side Effects Report #5663693-7
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Feb 22, 2008. Male patient, 31 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: acute graft versus host disease, adenoviral haemorrhagic cystitis, bacterial infection
, bone marrow transplant , complications of transplant surgery, cytomegalovirus antigen positive, renal failure, staphylococcal sepsis, stomatitis. Busulfan dosage: 34.0 ML;QD;IV. During the same period patient was treated with TACROLIMUS HYDRATE, CYCLOPHOSPHAMIDE, PHENYTOIN, FILGRASTIM, METHOTREXATE. Patient was hospitalized. Patient died.Busulfan Side Effects Report #5363111-2
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on June 01, 2007. Female patient, 21 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, multi-organ failure, neutrophil count decreased, staphylococcal sepsis. Busulfan dosage: unknown. During the same period patient was treated with PHENYTOIN, CYCLOPHOSPHAMIDE, METHOTREXATE, CYCLOSPORINE. Patient died on 05/05/2007.
Busulfan Side Effects Report #5447579-9
Busulfan side effect was reported by a Health Professional from JAPAN on Aug 22, 2007. Female patient, 21 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: cystitis haemorrhagic, diarrhoea, disseminated intravascular coagulation, malaise, multi-organ failure, nausea
, neutropenia, staphylococcal sepsis, stem cell transplant. Busulfan dosage: 6.2 ML;BID;IV; 6.2 ML;QID;IV; 6.2 ML;X1;IV. During the same period patient was treated with PHENYTOIN, CYCLOPHOSPHAMIDE, METHOTREXATE, CYCLOSPORINE. Patient died on 05/05/2007.Busulfan Side Effects Report #5503594-8
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Oct 15, 2007. Female patient, 21 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: bone marrow transplant
, candida sepsis, cardiogenic shock, pneumonia , staphylococcal sepsis, stomatitis. Busulfan dosage: 26 ML;QD;IV. During the same period patient was treated with FLUDARABINE PHOSPHATE, VALPROATE, NEUPOGEN, METHOTREXATE, TACROLIMUS. Patient recovered.Busulfan Side Effects Report #5523798-8
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Nov 05, 2007. Male patient, 21 years of age, was diagnosed with stem cell transplant, hyperbilirubinaemia and was treated with Busulfan. After drug was administered, patient experienced the following side effects: diarrhoea, hyperbilirubinaemia, staphylococcal sepsis, streptococcal sepsis. Busulfan dosage: 33.2 ML; QD; IV. During the same period patient was treated with MICAFUNGIN, CYCLOPHOSPHAMIDE, VALPROATE, NEUPOGEN, METHOTREXATE, CYCLOSPORINE. Patient recovered.
Busulfan Side Effects Report #5523802-7
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Nov 05, 2007. Female patient, 18 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: anorexia, malaise, nausea
, nystagmus, staphylococcal sepsis, vertigo. Busulfan dosage: 20 ML; QD; IV. During the same period patient was treated with PHENYTOIN, CYCLOPHOSPHAMIDE, NEUPOGEN, METHOTREXATE, TACROLIMUS. Patient recovered.Busulfan Side Effects Report #5570087-1
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Dec 03, 2007. Male patient, 17 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: blood pressure decreased, hepatic failure, metabolic acidosis, staphylococcal sepsis, stomatitis, thrombotic microangiopathy, venoocclusive disease. Busulfan dosage: 172 MG;QD;IV. During the same period patient was treated with FLUDARABINE PHOSPAHATE. Patient died on 09/13/2007.
Busulfan Side Effects Report #5663691-3
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Feb 22, 2008. Female patient, 16 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: anorexia, bone marrow transplant
, malaise, nausea , nystagmus, staphylococcal sepsis, stomatitis, vertigo. Busulfan dosage: 20 ML;QD;IV. During the same period patient was treated with PHENYTOIN, CYCLOPHOSPHAMIDE, FILGRASTIM, METHOTREXATE, TRACOLIMUS. Patient was hospitalized. Patient recovered.