Busulfan and ascites Patient Reports February 12, 2012

Busulfan Side Effects Report #5570101-3
Busulfan side effect was reported by a Health Professional from JAPAN on Dec 03, 2007. Male patient, 58 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: acute graft versus host disease, acute graft versus host disease in skin, anorexia, ascites, bk virus infection, blister, blood bilirubin increased, cystitis haemorrhagic, diarrhoea. Busulfan dosage: 31.72 ML;QD;IV. During the same period patient was treated with FLUDARABINE PHOSPHATE. Patient died on 09/11/2007.

Busulfan Side Effects Report #5385416-1
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on June 26, 2007. Male patient, 54 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: abdominal pain upper, ascites, blood bilirubin increased, blood lactate dehydrogenase increased, cystitis haemorrhagic, cytomegalovirus antibody positive, cytomegalovirus infection , diarrhoea, graft versus host disease. Busulfan dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE, VALPROATE. Patient died on 12/19/2006.

Busulfan Side Effects Report #5332532-6
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on May 07, 2007. Female patient, 39 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: ascites, blood pressure decreased, cardiac failure, coagulopathy, fluid retention, hypovolaemia, pathogen resistance, pleural effusion, pseudomonas infection. Busulfan dosage: 9.5 ML; QID; IV. During the same period patient was treated with VALPROATE, CYCLOPHOSPHAMIDE, LENOGRASTIM, METHOTREXATE, TACROLIMUS, PREDNISOLONE. Patient died on 03/27/2007.

Busulfan Side Effects Report #5313523-8
Busulfan side effect was reported by a Consumer or non-health professional from FRANCE on Apr 17, 2007. Female patient, child 1 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: anuria, ascites, dialysis , hyperbilirubinaemia, stem cell transplant, venoocclusive liver disease, weight increased. Busulfan dosage: unknown. During the same period patient was treated with ALKERAN, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.


Busulfan Side Effects Report #5528069-1
Busulfan side effect was reported by a Health Professional from JAPAN on Nov 09, 2007. Female patient, child .7 years of age, was diagnosed with stem cell transplant and was treated with Busulfan. After drug was administered, patient experienced the following side effects: ascites, continuous haemodiafiltration, dyspnoea, gallbladder enlargement, haematemesis, hepatic failure, hepatomegaly, hypopnoea, multi-organ failure. Busulfan dosage: 6.6 MG;QID;IV. Patient recovered.

Busulfan Side Effects Report #5671842-X
Busulfan side effect was reported by a Consumer or non-health professional from JAPAN on Mar 04, 2008. Male patient, child 4 years of age, was diagnosed with neuroblastoma  and was treated with Busulfan. After drug was administered, patient experienced the following side effects: abdominal pain , ascites, bile duct necrosis, bone marrow disorder, haematemesis, haematochezia, hepatic fibrosis, jaundice , oesophageal varices haemorrhage. Busulfan dosage: 16 MG/KG. During the same period patient was treated with ETOPOSIDE, MELPHALAN, CYCLOPHOSPHAMIDE, PIRARUBICIN, VINCRISTINE, CISPLATIN. Patient recovered.

Busulfan Side Effects Report #5509985-3
Busulfan side effect was reported by a Health Professional from UNITED STATES on Nov 07, 2007. Female patient, weighting 196.4 lb, was diagnosed with myeloid leukaemia and was treated with Busulfan. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase abnormal, ammonia increased, anorexia, ascites, aspartate aminotransferase abnormal, blood bilirubin increased, confusional state, gastritis. Busulfan dosage: .08 MG/KG -56.5 MG- Q 8 H FPR 16 DOSES IV BOLUS. During the same period patient was treated with CLOFARABINE. Patient was hospitalized. Patient recovered.

Busulfan Side Effects Report #4833756-4
Busulfan side effect was reported by a Health Professional from UNITED STATES on Nov 18, 2005. Male patient, weighting 140.0 lb, was diagnosed with chronic myeloid leukaemia and was treated with Busulfan. After drug was administered, patient experienced the following side effects: ascites, bronchoscopy abnormal, cytomegalovirus infection , gastritis, haematemesis, pancytopenia, post procedural complication, rectal haemorrhage, renal failure. Busulfan dosage: 333 MG DAILY IV DRIP. During the same period patient was treated with FLUDARABINE, CAMPATH. Patient was hospitalized. Patient recovered.

Busulfan Side Effects Report #5832346-4
Busulfan side effect was reported by a Consumer or non-health professional from UNITED STATES on July 23, 2008. Male patient, 25 years of age, was diagnosed with bone marrow transplant  and was treated with Busulfan. After drug was administered, patient experienced the following side effects: ascites, biliary tract disorder, cytomegalovirus infection , diarrhoea, encephalopathy, enterococcal sepsis, hepatic enzyme increased, hepatic function abnormal, hepatic vein thrombosis. Busulfan dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE. Patient died.


Busulfan Side Effects Report #5122933-3
Busulfan side effect was reported by a Health Professional from UNITED STATES on Oct 05, 2006. Male patient, 55 years of age, weighting 202.2 lb, was diagnosed with acute myeloid leukaemia and was treated with Busulfan. After drug was administered, patient experienced the following side effects: abdominal pain , ascites, blood bilirubin abnormal, oedema, stem cell transplant. Busulfan dosage: 50 MG/PO. During the same period patient was treated with BUSULFAN MUD TRANSPLANT, CYTOXAN, ESOMEPRAZOLE MAGNESIUM, DIPHENHYDRAMINE, HYDROMORPONE. Patient was hospitalized. Patient died.

Busulfan Side Effects Report #4608622-X
Busulfan side effect was reported by a Consumer or non-health professional from on Mar 11, 2005. Male patient, weighting 280.0 lb, was treated with Busulfan. After drug was administered, patient experienced the following side effects: ascites, blood iron increased, fatigue, hepatic cirrhosis, hepatic failure, hepatorenal syndrome, malaise, pleural effusion, transplant rejection. Busulfan dosage: 1MG/KG PO Q6H X 16 DOSES ON DAYS -7 TO -4.. During the same period patient was treated with ETOPOSIDE, NEUPOGEN. Patient died on 02/17/2005.