Briplatin and liver disorder Patient Reports February 12, 2012

Briplatin Side Effects Report #5767316-8
Briplatin side effect was reported by a Physician from JAPAN on June 10, 2008. Male patient, 77 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: bone marrow failure, interstitial lung disease, liver disorder, renal impairment. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN, CELTECT, BISOLVON, OXYCONTIN. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5780018-7
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on June 17, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: febrile neutropenia, interstitial lung disease, liver disorder, platelet count decreased, renal impairment. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN, CELTECT, BISOLVON, OXYCONTIN. Patient was hospitalized. Patient died.

Briplatin Side Effects Report #5802649-8
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on July 03, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, febrile neutropenia and was treated with Briplatin. After drug was administered, patient experienced the following side effects: febrile neutropenia, interstitial lung disease, liver disorder, platelet count decreased, renal impairment. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PAZUCROSS, MEROPEN, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN, CELTECT. Patient was hospitalized. Patient died on 05/13/2008.

Briplatin Side Effects Report #5807027-3
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on July 10, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, febrile neutropenia and was treated with Briplatin. After drug was administered, patient experienced the following side effects: febrile neutropenia, interstitial lung disease, liver disorder, platelet count decreased, renal impairment. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PAZUCROSS, MEROPEN, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN, CELTECT. Patient was hospitalized. Patient died on 05/13/2008.


Briplatin Side Effects Report #5857402-6
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 21, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, febrile neutropenia, bone marrow failure and was treated with Briplatin. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, bone marrow failure, febrile neutropenia, interstitial lung disease, liver disorder, malignant neoplasm progression, multi-organ failure. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PAZUCROSS, MEROPEN, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN. Patient was hospitalized. Patient died on 05/13/2008.