Briplatin and bone marrow failure Patient Reports February 12, 2012

Briplatin Side Effects Report #6083620-0
Briplatin side effect was reported by a Health Professional from JAPAN on Feb 13, 2009. Female patient, 54 years of age, was diagnosed with squamous cell carcinoma and was treated with Briplatin. After drug was administered, patient experienced the following side effects: bone marrow failure, duodenal perforation, oedema peripheral. Briplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL. Patient recovered.

Briplatin Side Effects Report #5767316-8
Briplatin side effect was reported by a Physician from JAPAN on June 10, 2008. Male patient, 77 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: bone marrow failure, interstitial lung disease, liver disorder, renal impairment. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN, CELTECT, BISOLVON, OXYCONTIN. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5857402-6
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 21, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, febrile neutropenia, bone marrow failure and was treated with Briplatin. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, bone marrow failure, febrile neutropenia, fluid retention, hypercapnia, interstitial lung disease, liver disorder. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PAZUCROSS, MEROPEN, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN. Patient was hospitalized. Patient died on 05/13/2008.

Briplatin Side Effects Report #5857402-6
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 21, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, febrile neutropenia, bone marrow failure and was treated with Briplatin. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, bone marrow failure, febrile neutropenia, interstitial lung disease, liver disorder, malignant neoplasm progression, multi-organ failure. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PAZUCROSS, MEROPEN, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN. Patient was hospitalized. Patient died on 05/13/2008.


Briplatin Side Effects Report #4791645-8
Briplatin side effect was reported by a Physician from JAPAN on Sept 28, 2005. Male patient, 65 years of age, was diagnosed with gastric cancer and was treated with Briplatin. After drug was administered, patient experienced the following side effects: bone marrow failure, diarrhoea, ileus. Briplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, SOLITA, NASEA. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #4923359-5
Briplatin side effect was reported by a Physician from JAPAN on Sept 28, 2005. Male patient, 65 years of age, was diagnosed with gastric cancer and was treated with Briplatin. After drug was administered, patient experienced the following side effects: abdominal pain , bone marrow failure, diarrhoea, ileus, nausea . Briplatin dosage: unknown. During the same period patient was treated with MAXIPIME, FLUOROURACIL, SOLITA, NASEA, ISOTONIC CHLORIDE. Patient was hospitalized. Patient recovered.