Briplatin and blood lactate dehydrogenase increased Patient Reports February 12, 2012

Briplatin Side Effects Report #5857402-6
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 21, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, febrile neutropenia, bone marrow failure and was treated with Briplatin. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, bone marrow failure, febrile neutropenia, fluid retention, hypercapnia, interstitial lung disease, liver disorder. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PAZUCROSS, MEROPEN, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN. Patient was hospitalized. Patient died on 05/13/2008.

Briplatin Side Effects Report #5857402-6
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 21, 2008. Male patient, 77 years of age, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, febrile neutropenia, bone marrow failure and was treated with Briplatin. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, bone marrow failure, febrile neutropenia, interstitial lung disease, liver disorder, malignant neoplasm progression, multi-organ failure. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PAZUCROSS, MEROPEN, PANVITAN, CYANOCOBALAMIN, AMARYL, BASEN. Patient was hospitalized. Patient died on 05/13/2008.

Briplatin Side Effects Report #5455347-7
Briplatin side effect was reported by a Health Professional from JAPAN on Sept 13, 2007. Female patient, 72 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: amyloidosis, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, decreased appetite, diarrhoea, febrile neutropenia, gastric ulcer. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, MECOBALAMIN, FERROMIA, URSO, FLOPROPIONE, TANNALBIN, ALFAROL. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5458658-4
Briplatin side effect was reported by a Health Professional from JAPAN on Sept 13, 2007. Female patient, 72 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: amyloidosis, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, decreased appetite, diarrhoea, febrile neutropenia, gastric ulcer. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, MECOBALAMIN, FERROMIA, URSO, FLOPROPIONE, TANNALBIN, ALFAROL. Patient was hospitalized. Patient recovered.


Briplatin Side Effects Report #5480660-7
Briplatin side effect was reported by a Health Professional from JAPAN on Sept 28, 2007. Female patient, 72 years of age, weighting 85.98 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: amyloidosis, anorexia, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, diarrhoea, febrile neutropenia, gastric ulcer. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, PANVITAN, METHYCOBAL, FERROMIA, URSO, FLOPROPIONE, TANNALBIN, ALFAROL. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5500765-1
Briplatin side effect was reported by a Health Professional from JAPAN on Oct 24, 2007. Female patient, 72 years of age, weighting 85.98 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: amyloidosis, anorexia, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, diarrhoea, febrile neutropenia, gastric ulcer. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, RANDA, PANVITAN, METHYCOBAL, FERROMIA, URSO, FLOPROPIONE, TANNALBIN. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5510153-X
Briplatin side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 06, 2007. Female patient, 72 years of age, weighting 85.98 lb, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: amyloidosis, anorexia, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, diarrhoea, febrile neutropenia, gastric ulcer. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA, RANDA, PANVITAN, METHYCOBAL, FERROMIA, URSO, FLOPROPIONE, TANNALBIN. Patient was hospitalized. Patient recovered.

Briplatin Side Effects Report #5499191-3
Briplatin side effect was reported by a Health Professional from JAPAN on Oct 24, 2007. Female patient, 52 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Briplatin. After drug was administered, patient experienced the following side effects: anaphylactic reaction, arteriosclerosis, blood lactate dehydrogenase increased, blood urea, bronchitis , constipation , hepatic enzyme increased, lymphocyte count decreased. Briplatin dosage: unknown. During the same period patient was treated with ALIMTA. Patient recovered.