Bosentan and decreased appetite Patient Reports February 11, 2012

Bosentan Side Effects Report #4586772-4
Bosentan side effect was reported by a Pharmacist from on Feb 17, 2005. Male patient, 79 years of age, weighting 200.6 lb, was diagnosed with pulmonary hypertension , heart valve replacement and was treated with Bosentan. After drug was administered, patient experienced the following side effects: asthenia, decreased appetite, fluid retention, international normalised ratio increased, liver function test abnormal, malaise, pneumonia . Bosentan dosage: unknown. During the same period patient was treated with WARFARIN NOT DOCUMENTED NOT DOCUMENTED. Patient was hospitalized. Patient recovered.

Bosentan Side Effects Report #4692174-2
Bosentan side effect was reported by a Consumer or non-health professional from on June 03, 2005. Male patient, 55 years of age, was diagnosed with pulmonary hypertension  and was treated with Bosentan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, decreased appetite, gamma-glutamyltransferase increased, hepatic function abnormal, nasopharyngitis, pyrexia. Bosentan dosage: unknown. During the same period patient was treated with WARFARIN, LANIRAPID, MARZULENE, PROTECADIN. Patient was hospitalized. Patient recovered.