Bosentan and cholangiolitis Patient Reports February 11, 2012

Bosentan Side Effects Report #4802959-7
Bosentan side effect was reported by a Physician from NETHERLANDS on Sept 29, 2005. Female patient, 23 years of age, was diagnosed with pulmonary hypertension  and was treated with Bosentan. After drug was administered, patient experienced the following side effects: abdominal pain , autoimmune hepatitis, blood albumin decreased, blood immunoglobulin g increased, blood urine present, cholangiolitis, dilatation ventricular, erosive duodenitis, gastrointestinal haemorrhage. Bosentan dosage: unknown. During the same period patient was treated with MARCUMAR, IMURAN, ALENDRONATE, CALCICHEW, SINTROM MITIS, HYDROCORT. Patient was hospitalized. Patient recovered.

Bosentan Side Effects Report #4824740-5
Bosentan side effect was reported by a Physician from NETHERLANDS on Oct 25, 2005. Female patient, 23 years of age, was diagnosed with pulmonary hypertension  and was treated with Bosentan. After drug was administered, patient experienced the following side effects: abdominal haematoma, abdominal pain , ascites, autoimmune hepatitis, blood albumin decreased, blood amylase increased, blood potassium decreased, cholangiolitis, erosive duodenitis. Bosentan dosage: unknown. During the same period patient was treated with MARCUMAR, IMURAN, ALENDRONATE, CALCICHEW, SINTROM MITIS, HYDROCORT. Patient was hospitalized. Patient recovered.

Bosentan Side Effects Report #4777919-5
Bosentan side effect was reported by a Physician from NETHERLANDS on Sept 05, 2005. Female patient, 23 years of age, was treated with Bosentan. After drug was administered, patient experienced the following side effects: blood albumin decreased, cholangiolitis, haematocrit decreased, haemoglobin decreased, hepatitis , international normalised ratio increased, pneumonia viral, retroperitoneal haematoma, upper gastrointestinal haemorrhage. Bosentan dosage: unknown. During the same period patient was treated with MARCUMAR, ALENDRONATE, CALCICHEW, SINTROM MITIS, HYDROCORT, PREDNISOLONE. Patient was hospitalized. Patient recovered.