Bortezomib and hypotension Patient Reports February 12, 2012

Bortezomib Side Effects Report #4941157-3
Bortezomib side effect was reported by a Physician from UNITED STATES on Mar 10, 2006. Female patient, weighting 134.5 lb, was diagnosed with waldenstrom's macroglobulinaemia and was treated with Bortezomib. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, bacterial infection , chills, diarrhoea, disseminated intravascular coagulation, herpes zoster, hypotension, international normalised ratio increased, pyrexia. Bortezomib dosage: 2.6 MG IV. During the same period patient was treated with DEXAMETHASONE, RITUXIMAB. Patient was hospitalized. Patient recovered.

Bortezomib Side Effects Report #5345329-8
Bortezomib side effect was reported by a Health Professional from UNITED STATES on June 01, 2007. Female patient, 60 years of age, weighting 111.0 lb, was diagnosed with squamous cell carcinoma and was treated with Bortezomib. After drug was administered, patient experienced the following side effects: diarrhoea, hypotension. Bortezomib dosage: 1.6MG/M2 IV DAYS 1+8. During the same period patient was treated with DOCETAXEL, PREVACID, PREMARIN, SYNTHROID, LEXAPRO, MEGACE, PHENERGAN, KYTRIL. Patient was hospitalized. Patient recovered.

Bortezomib Side Effects Report #5143381-6
Bortezomib side effect was reported by a Health Professional from UNITED STATES on Nov 01, 2006. Female patient, 50 years of age, weighting 200.0 lb, was diagnosed with mantle cell lymphoma and was treated with Bortezomib. After drug was administered, patient experienced the following side effects: blood culture positive, body temperature decreased, catheter related infection, compression fracture, depressed level of consciousness, hypotension, mental status changes, oxygen saturation decreased, rib fracture. Bortezomib dosage: 2.4MG D1+4 IV. During the same period patient was treated with BORTEZOMIB IV, CYCLOPHOSPHAMIDE, RITUXAN, DOXORUBICIN, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Bortezomib Side Effects Report #6078512-7
Bortezomib side effect was reported by a Health Professional from UNITED STATES on Feb 11, 2009. Male patient, weighting 186.0 lb, was diagnosed with adenoid cystic carcinoma and was treated with Bortezomib. After drug was administered, patient experienced the following side effects: diarrhoea, dizziness , hypotension. Bortezomib dosage: 1.3 MG/M2 TWICE WEEKLY IV BOLUS. During the same period patient was treated with ADRIAMYCIN PFS, KYTRIL, COMPAZINE PRN. Patient was hospitalized. Patient recovered.


Bortezomib Side Effects Report #5506009-9
Bortezomib side effect was reported by a Pharmacist from UNITED STATES on Nov 01, 2007. Female patient, weighting 158.7 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Bortezomib. After drug was administered, patient experienced the following side effects: blood phosphorus decreased, chills, hypotension, incontinence, loss of consciousness, pain , rhabdomyolysis. Bortezomib dosage: 2.3MG ONCE IV. During the same period patient was treated with DOXORUBICIN. Patient recovered.