Bone and implant site reaction Patient Reports February 12, 2012

Bone Side Effects Report #4963516-5
Bone side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 04, 2006. Female patient, 53 years of age, weighting 155.0 lb, was diagnosed with surgery  and was treated with Bone. After drug was administered, patient experienced the following side effects: arthropathy, cardiac valve disease, eye disorder, graft complication, heart valve insufficiency, immune system disorder, implant site reaction, inflammation, multi-organ disorder. Bone dosage: unknown. During the same period patient was treated with STRYKER BIOTECH BMP BONE GRAFT MATERIAL, VITROSS SCAFFOLD FOAM BONE GRAFT MATERIAL, ORTHOVITA MALVERN. Patient was hospitalized. Patient recovered.

Bone Side Effects Report #5064902-8
Bone side effect was reported by a Consumer or non-health professional from UNITED STATES on July 27, 2006. Male patient, 82 years of age, was treated with Bone. After drug was administered, patient experienced the following side effects: agitation, cardiopulmonary failure, implant site reaction, loss of consciousness, post procedural complication. Bone dosage: unknown. Patient died on 07/25/2006.