Bevacizumab and intestinal obstruction Patient Reports February 10, 2012

Bevacizumab Side Effects Report #5660899-8
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 26, 2008. Male patient was diagnosed with rectal cancer recurrent and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction, pain in extremity, sepsis

. Bevacizumab dosage: 5 MG/KG, Q2W. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, FLUOROURACIL, ISOVORIN. Patient died on 11/20/2007.

Bevacizumab Side Effects Report #5558287-8
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 29, 2007. Male patient was diagnosed with rectal cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction, pain in extremity, sepsis

. Bevacizumab dosage: 5 MG/KG, Q2W. During the same period patient was treated with IRINOTECAN, ISOVORIN, FLUOROURACIL. Patient died on 11/20/2007.

Bevacizumab Side Effects Report #5953349-5
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 07, 2008. Female patient, weighting 162.0 lb, was diagnosed with pancreatic carcinoma and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 10 MG/KG, DAYS 1+15. During the same period patient was treated with GEMCITABINE, FLUOROURACIL, OXYCODONE, METFORMIN, GLIMEPIRIDE, NORVASC, ATIVAN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5812168-0
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on July 02, 2008. Female patient was diagnosed with ovarian epithelial cancer, ovarian cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 375 MG, Q3W. During the same period patient was treated with CARBOPLATIN, PACLITAXEL, KEVATRIL, CLEMASTINE FUMARATE, RANITIDINE, METOPROLOL TARTRATE, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5872571-X
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Aug 22, 2008. Female patient was diagnosed with ovarian epithelial cancer, ovarian cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal ischaemia, intestinal obstruction, pelvic abscess. Bevacizumab dosage: 450 MG, Q3W. During the same period patient was treated with PACLITAXEL, CARBOPLATIN, LISINOPRIL, ACETAMINOPHEN, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5957385-4
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Nov 06, 2008. Female patient was diagnosed with ovarian epithelial cancer, ovarian cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction, small intestinal obstruction. Bevacizumab dosage: 442 MG, Q3W. During the same period patient was treated with PACLITAXEL, CARBOPLATIN, ACETAMINOPHEN, TRAMADOL, MEDROXYPROGESTERONE, PREMARIN, AMITRIPTYLINE, SPIRONOLACTONE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5991132-5
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Nov 27, 2008. Female patient was diagnosed with ovarian epithelial cancer, ovarian cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction, small intestinal obstruction, vomiting. Bevacizumab dosage: 442 MG, Q3W. During the same period patient was treated with PACLITAXEL, CARBOPLATIN, ACETAMINOPHEN, TRAMADOL, MEDROXYPROGESTERONE, PREMARIN, AMITRIPTYLINE, SPIRONOLACTONE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5518137-2
Bevacizumab side effect was reported by a Health Professional from UNITED STATES on Nov 13, 2007. Female patient, 70 years of age, weighting 134.5 lb, was diagnosed with ovarian cancer metastatic, ovarian cancer recurrent and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: anaemia, intestinal obstruction, neutropenia, thrombocytopenia. Bevacizumab dosage: 10MG/1 D KG DAYS 1, 15. During the same period patient was treated with HYCAMTIN, CALCIUM, SYNTHROID, GLUCOSAMINE, VYTORIN, ATENOLOL, COMPAZINE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5508347-2
Bevacizumab side effect was reported by a Health Professional from UNITED STATES on Oct 25, 2007. Female patient, weighting 134.5 lb, was diagnosed with ovarian cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction, neutropenia, thrombocytopenia. Bevacizumab dosage: 590 MG, DAYS 1+15. During the same period patient was treated with TOPOTECAN, DARBEPOETIN ALFA, NEUPOGEN, CALCIUM, SYNTHROID, GLUCOSAMINE, CHONDROITIN, VYTORIN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5510683-0
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Oct 24, 2007. Female patient was diagnosed with ovarian cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal ischaemia, intestinal obstruction. Bevacizumab dosage: 450 MG, Q3W. During the same period patient was treated with PACLITAXEL, CARBOPLATIN, LISINOPRIL, PARACETAMOL, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5717133-X
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Apr 10, 2008. Female patient was diagnosed with ovarian cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal ischaemia, intestinal obstruction, pelvic abscess. Bevacizumab dosage: 450 MG, Q3W. During the same period patient was treated with PACLITAXEL, CARBOPLATIN, LISINOPRIL, PARACETAMOL, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5751097-8
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on May 13, 2008. Female patient was diagnosed with ovarian cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: adhesion

, anastomotic leak, clostridium difficile colitis, diarrhoea, enterocutaneous fistula, intestinal gangrene, intestinal ischaemia, intestinal obstruction, pelvic abscess. Bevacizumab dosage: 450 MG, Q3W. During the same period patient was treated with PACLITAXEL, CARBOPLATIN, LISINOPRIL, ACETAMINOPHEN, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5814199-3
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED STATES on July 09, 2008. Male patient was diagnosed with non-small cell lung cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: abdominal abscess, colonic stenosis, diverticulitis, gastrointestinal necrosis, ileus, intestinal obstruction, intestinal perforation, peritonitis. Bevacizumab dosage: 15 MG/KG, Q21D. During the same period patient was treated with ALIMTA, CARBOPLATIN, ENZASTAURIN, ADVICOR, ASPIRIN, FOLIC ACID, METOPROLOL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5823535-3
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED STATES on July 18, 2008. Male patient was diagnosed with non-small cell lung cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: abdominal abscess, colonic stenosis, diverticulitis, gastrointestinal necrosis, ileus, intestinal obstruction, intestinal perforation, peritonitis. Bevacizumab dosage: 15 MG/KG, Q21D. During the same period patient was treated with ALIMTA, CARBOPLATIN, ADVICOR, ASPIRIN, FOLIC ACID, METOPROLOL TARTRATE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5845819-5
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 06, 2008. Male patient was diagnosed with non-small cell lung cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: abdominal abscess, colonic stenosis, diverticulitis, gastrointestinal necrosis, ileus, intestinal obstruction, intestinal perforation, peritonitis. Bevacizumab dosage: 15 MG/KG, Q21D. During the same period patient was treated with ALIMTA, CARBOPLATIN, ADVICOR, ASPIRIN, FOLIC ACID, METOPROLOL SUCCINATE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5885599-0
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 08, 2008. Male patient was diagnosed with non-small cell lung cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: abdominal abscess, colonic stenosis, diverticulitis, gastrointestinal necrosis, ileus, intestinal obstruction, intestinal perforation, peritonitis. Bevacizumab dosage: 15 MG/KG, Q21D. During the same period patient was treated with ALIMTA, CARBOPLATIN, ADVICOR, ASPIRIN, FOLIC ACID, METOPROLOL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5958852-X
Bevacizumab side effect was reported by a Health Professional from UNITED STATES on Nov 12, 2008. Female patient, weighting 238.0 lb, was diagnosed with non-small cell lung cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: back pain

, hernia

, hypoglycaemia, intestinal obstruction. Bevacizumab dosage: 1050 MG, Q2W. During the same period patient was treated with ALIMTA, GEMZAR, METFORMIN, PREDNISONE, ADVAIR DISKUS, SPIRIVA, ALBUTEROL, LIPITOR. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #6086396-6
Bevacizumab side effect was reported by a Health Professional from UNITED STATES on Feb 12, 2009. Male patient, weighting 193.0 lb, was diagnosed with non-small cell lung cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: dehydration, haematocrit decreased, intestinal obstruction, intestinal perforation, platelet count increased, pneumoperitoneum, sepsis

. Bevacizumab dosage: 875 MG, UNK. During the same period patient was treated with GEMCITABINE, PACLITAXEL, ASPIRIN, COMBIVENT, LIPITOR, ZEBETA, ZYRTEC, ZOFRAN. Patient was hospitalized. Patient died on 02/08/2009.

Bevacizumab Side Effects Report #5526450-8
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 21, 2007. Male patient, weighting 158.7 lb, was diagnosed with metastatic gastric cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: febrile neutropenia, intestinal obstruction. Bevacizumab dosage: 10MG/MG2 IV BOLUS. During the same period patient was treated with DOCETAXEL, CISPLATIN, IRINOTECAN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5528262-8
Bevacizumab side effect was reported by a Physician from UNITED STATES on Nov 20, 2007. Male patient was diagnosed with metastatic gastric cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction, neutropenia, pyrexia. Bevacizumab dosage: 10 MG/M2, Q3W. During the same period patient was treated with DOCETAXEL, CISPLATIN, IRINOTECAN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5333448-1
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on May 09, 2007. Male patient was diagnosed with colorectal cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: diarrhoea, intestinal obstruction, nausea

, sepsis

. Bevacizumab dosage: 510 MG, UNK. During the same period patient was treated with XELODA, NEXIUM, ACTONEL, TEMAZEPAM, ASPIRIN, SOLPRIN, PARIET, SALBUTAMOL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5395582-X
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on July 09, 2007. Male patient was diagnosed with colorectal cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: diarrhoea, intestinal obstruction, nausea

. Bevacizumab dosage: 7.5 MG/M2, Q3W. During the same period patient was treated with CAPECITABINE, MITOMYCIN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5792226-X
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on June 12, 2008. Male patient was diagnosed with colorectal cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 600 MG, Q3W. During the same period patient was treated with CAPECITABINE, VASOTEC, IMODIUM, TYLENOL EXTRA STRENGTH, DILAUDID, LOMOTIL, PROCHLORPERAZINE, LIPITOR. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5798780-6
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on June 17, 2008. Female patient was diagnosed with colorectal cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 487 MG, UNK. During the same period patient was treated with OXALIPLATIN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5802412-8
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on June 19, 2008. Male patient was diagnosed with colorectal cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 600 MG, Q3W. During the same period patient was treated with CAPECITABINE, VASOTEC, IMODIUM, TYLENOL EXTRA STRENGTH, DILAUDID, LOMOTIL, PROCHLORPERAZINE, LIPITOR. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5937744-6
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 20, 2008. Female patient was diagnosed with colorectal cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 250 MG, Q2W. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, FLUOROURACIL, LEUCOVORIN CALCIUM, OMEPRAZOLE. Patient recovered.

Bevacizumab Side Effects Report #6094657-X
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Feb 13, 2009. Male patient, weighting 147.7 lb, was diagnosed with colorectal cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: ileus paralytic, intestinal obstruction. Bevacizumab dosage: 500 MG, Q3W. During the same period patient was treated with CAPECITABINE, MITOMYCIN, NIZATIDINE, LISINOPRIL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5174214-X
Bevacizumab side effect was reported by a Physician from UNITED STATES on Nov 22, 2006. Male patient, 61 years of age, weighting 177.3 lb, was diagnosed with colorectal cancer

and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, diarrhoea, hypokalaemia, hypomagnesaemia, hyponatraemia, hypophosphataemia, intestinal obstruction, nausea

. Bevacizumab dosage: 5 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with OXALIPLATIN, ATENOLOL, PLAVIX, DIOVAN, COMPAZINE, IMODIUM, VITAMIN B, FOLIC ACID. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5187716-7
Bevacizumab side effect was reported by a Health Professional from UNITED STATES on Dec 05, 2006. Male patient, 61 years of age, weighting 177.3 lb, was diagnosed with colorectal cancer

and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: blood sodium decreased, hypokalaemia, intestinal obstruction. Bevacizumab dosage: 5 MG/KG Q2W INTRAVENOUS. During the same period patient was treated with OXALIPLATIN, ATENOLOL, PLAVIX, DIOVAN, COMPAZINE, IMODIUM, VITMAIN B, FOLIC ACID. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5198024-2
Bevacizumab side effect was reported by a Health Professional from UNITED STATES on Dec 19, 2006. Male patient, 61 years of age, weighting 177.3 lb, was diagnosed with colorectal cancer

and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: adhesion

, diarrhoea, hypokalaemia, hypomagnesaemia, hyponatraemia, hypophosphataemia, intestinal obstruction, metastases to peritoneum, nausea

. Bevacizumab dosage: 5 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with OXALIPLATIN, CAPECITABINE, ATENOLOL, PLAVIX, DIOVAN, COMPAZINE, IMODIUM, VITAMIN B. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5306023-2
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 24, 2007. Male patient, weighting 177.3 lb, was diagnosed with colorectal cancer

and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: hypokalaemia, hypomagnesaemia, hyponatraemia, hypophosphataemia, intestinal obstruction, metastases to peritoneum. Bevacizumab dosage: 5 MG/KG, Q2W. During the same period patient was treated with OXALIPLATIN, CAPECITABINE, ATENOLOL, PLAVIX, DIOVAN, COMPAZINE, IMODIUM, VITAMIN B. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5375181-6
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on June 14, 2007. Female patient was diagnosed with colorectal cancer

and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 380 MG, Q2W. During the same period patient was treated with CAPECITABINE, OXALIPLATIN, LANSOPRAZOLE, PREDNISONE, PLASIL, NEORECORMON, BARNIDIPINE HYDROCHLORIDE. Patient was hospitalized. Patient died.

Bevacizumab Side Effects Report #5826095-6
Bevacizumab side effect was reported by a Physician from UNITED STATES on July 21, 2008. Female patient, weighting 138.0 lb, was diagnosed with colorectal cancer

and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 5 MG/KG, Q2W. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5844082-9
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on July 29, 2008. Male patient was diagnosed with colorectal cancer

, colorectal cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 330 MG, Q2W. During the same period patient was treated with IRINOTECAN, FLUOROURACIL. Patient recovered.

Bevacizumab Side Effects Report #5848793-0
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on June 11, 2008. Female patient, 40 years of age, was diagnosed with colon cancer recurrent, prophylaxis of nausea and vomiting and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: abdominal pain

, intestinal obstruction. Bevacizumab dosage: 5 MG/KG, UNK. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL, ISOVORIN, IRINOTECAN, KYTRIL, DECADRON SRC, MAGNESIUM OXIDE, LOXOPROFEN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5558185-X
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Dec 04, 2007. Female patient was diagnosed with colon cancer recurrent and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction, renal failure acute. Bevacizumab dosage: 5 MG/KG, Q2W. During the same period patient was treated with OXALIPLATIN, ISOVORIN, FLUOROURACIL, ASPIRIN, ADALAT, BISOPROLOL, FRANDOL, GASTER. Patient recovered.

Bevacizumab Side Effects Report #5714981-7
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Apr 08, 2008. Female patient was diagnosed with colon cancer recurrent and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood creatinine increased, dehydration, haemodialysis, ileus, intestinal obstruction, neutrophil count decreased. Bevacizumab dosage: 5 MG/KG, Q2W. During the same period patient was treated with OXALIPLATIN, ISOVORIN, FLUOROURACIL, ASPIRIN, ADALAT, BISOPROLOL FUMARATE, FRANDOL, FAMOTIDINE. Patient recovered.

Bevacizumab Side Effects Report #5692676-6
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Mar 20, 2008. Male patient, weighting 156.5 lb, was diagnosed with colon cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 355 MG, Q2W. During the same period patient was treated with IRINOTECAN, FLUOROURACIL, FOLINIC ACID. Patient was hospitalized and became disabled. Patient recovered.

Bevacizumab Side Effects Report #5707577-4
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Apr 01, 2008. Male patient, weighting 156.5 lb, was diagnosed with colon cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 355 MG, Q2W. During the same period patient was treated with IRINOTECAN, FLUOROURACIL, FOLINIC ACID. Patient was hospitalized and became disabled. Patient recovered.

Bevacizumab Side Effects Report #6044822-2
Bevacizumab side effect was reported by a Physician from JAPAN on May 19, 2008. Male patient, weighting 142.6 lb, was diagnosed with colon cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction, neutrophil count decreased. Bevacizumab dosage: 5 MG/KG, UNK. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, FLUOROURACIL, ISOVORIN, AMLODINE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5575073-3
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Dec 12, 2007. Female patient, 40 years of age, was diagnosed with colon cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 5 MG/KG, UNK. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL, ISOVORIN, IRINOTECAN, KYTRIL, DECADRON, MAGNESIUM OXIDE, LOXOPROFEN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5600618-4
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Jan 08, 2008. Female patient, 40 years of age, was diagnosed with colon cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: abdominal pain

, intestinal obstruction. Bevacizumab dosage: 5 MG/KG, UNK. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL, ISOVORIN, IRINOTECAN, KYTRIL, DECADRON, MAGNESIUM OXIDE, LOXOPROFEN. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5319420-6
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Apr 23, 2007. Male patient, weighting 136.7 lb, was diagnosed with colon cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: anal fistula, intestinal obstruction. Bevacizumab dosage: 315 MG, Q2W. During the same period patient was treated with OXALIPLATIN, LEUCOVORIN CALCIUM, FLUOROURACIL, NORVASC, TRIATEC. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5494763-4
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 10, 2007. Female patient was diagnosed with colon cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 5 MG/KG, QD. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL, ISOVORIN, KYTRIL, DECADRON, AMOBAN. Patient died.

Bevacizumab Side Effects Report #5512016-2
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Oct 26, 2007. Male patient was diagnosed with colon cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 5 MG/KG, Q2W. During the same period patient was treated with IRINOTECAN, FLUOROURACIL, ISOVORIN, ETODOLAC, BLOPRESS, PAXIL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5514761-1
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 29, 2007. Female patient was diagnosed with colon cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: disease progression, gastrointestinal perforation, intestinal obstruction, wound dehiscence. Bevacizumab dosage: 5 MG/KG, QD. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL, ISOVORIN, KYTRIL, DECADRON, AMOBAN. Patient died on 10/03/2007.

Bevacizumab Side Effects Report #5534734-2
Bevacizumab side effect was reported by a Physician from UNITED KINGDOM on Nov 21, 2007. Male patient was diagnosed with colon cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: diarrhoea, intestinal obstruction. Bevacizumab dosage: 5 MG/KG, Q2W. During the same period patient was treated with IRINOTECAN, FLUOROURACIL, ISOVORIN, ETODOLAC, BLOPRESS, PAXIL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5740915-5
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 02, 2008. Male patient, weighting 147.7 lb, was diagnosed with colon cancer and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: abdominal pain

, intestinal obstruction, small intestinal obstruction. Bevacizumab dosage: 494 MG, Q3W. During the same period patient was treated with XELODA, METOCLOPRAMIDE, LOPERAMIDE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #4662962-7
Bevacizumab side effect was reported by a Physician from on Apr 29, 2005. Female patient, 64 years of age, weighting 146.8 lb, was diagnosed with clear cell carcinoma of the kidney and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction, large intestine perforation, pelvic abscess, postoperative wound complication, wound decomposition, wound secretion. Bevacizumab dosage: 10 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with INTERFERON ALFA, DEXAMETHASONE, COVERSYL, XALATAN, CARDIZEM, METOCLOPRAMIDE. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5797226-1
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on June 16, 2008. Female patient was diagnosed with breast cancer metastatic and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 1110 MG, Q3W. During the same period patient was treated with DURAGESIC, COAPROVEL. Patient was hospitalized. Patient recovered.

Bevacizumab Side Effects Report #5449684-X
Bevacizumab side effect was reported by a Health Professional from UNITED STATES on Sept 10, 2007. Male patient, 67 years of age, weighting 220.5 lb, was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 1000MG. Patient was hospitalized. Patient died on 08/29/2007.

Bevacizumab Side Effects Report #5455618-4
Bevacizumab side effect was reported by a Health Professional from UNITED STATES on Sept 07, 2007. Male patient, 67 years of age, weighting 220.5 lb, was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 1000 MG, UNK. Patient was hospitalized. Patient died on 08/29/2007.

Bevacizumab Side Effects Report #5477524-1
Bevacizumab side effect was reported by a Health Professional from UNITED STATES on Sept 07, 2007. Male patient, 67 years of age, weighting 220.5 lb, was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 1000 MG, UNK. Patient was hospitalized. Patient died on 08/29/2007.

Bevacizumab Side Effects Report #5509999-3
Bevacizumab side effect was reported by a Health Professional from UNITED STATES on Nov 01, 2007. Male patient, 67 years of age, weighting 208.0 lb, was diagnosed with chills, diarrhoea and was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: intestinal obstruction. Bevacizumab dosage: 1000 MG, UNK. During the same period patient was treated with DIOVAN HCT, HUMALOG, HYDROMORPHONE, IMODIUM, LANTUS, NASONEX, NORVASC, TOPROL. Patient was hospitalized. Patient died on 08/29/2007.

Bevacizumab Side Effects Report #5724869-3
Bevacizumab side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 30, 2008. Female patient, weighting 110.2 lb, was treated with Bevacizumab. After drug was administered, patient experienced the following side effects: ascites, gastrointestinal anastomotic leak, haemoglobin decreased, intestinal obstruction, intra-abdominal haemorrhage, neuropathy peripheral, post procedural complication, retroperitoneal haemorrhage. Bevacizumab dosage: 508 MG. During the same period patient was treated with LEUCOVORIN CALCIUM, ELOXATIN, FLUOROURACIL, HYDROCLORATHIAZIDE, RAMIPRAL. Patient was hospitalized. Patient recovered.

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Bevacizumab and intestinal obstruction Patient Reports February 10, 2012

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