Atgam and alanine aminotransferase increased Patient Reports February 13, 2012

Atgam Side Effects Report #4713493-7
Atgam side effect was reported by a Physician from UNITED STATES on June 21, 2005. Male patient, 50 years of age, weighting 263.2 lb, was diagnosed with myelodysplastic syndrome and was treated with Atgam. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, alanine aminotransferase increased, atrioventricular block second degree, hyperbilirubinaemia, hypersensitivity, hypocalcaemia, hypomagnesaemia, infusion related reaction, international normalised ratio increased. Atgam dosage: 4820 MG (QD), INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, FUROSEMIDE, METHYLPREDNISOLONE, HYDROCORTISONE, LEVOXYL, TESTOSTERONE, TROGLITAZONE, NEXIUM. Patient was hospitalized. Patient recovered.

Atgam Side Effects Report #5616687-1
Atgam side effect was reported by a Health Professional from AUSTRALIA on Jan 31, 2008. Male patient, 60 years of age, was diagnosed with renal transplant and was treated with Atgam. After drug was administered, patient experienced the following side effects: agitation, alanine aminotransferase increased, aspartate aminotransferase increased, blood creatinine increased, blood lactate dehydrogenase increased, cardiogenic shock, chest x-ray abnormal, hypotension, hypoxia. Atgam dosage: unknown. During the same period patient was treated with CYCLOSPORINE, MYCOPHENOLATE MOFETIL, PREDNISOLONE. Patient died.