Arsenic and disseminated intravascular coagulation Patient Reports February 12, 2012

Arsenic Side Effects Report #5853388-9
Arsenic side effect was reported by a Physician from ITALY on Dec 06, 2007. Male patient, 65 years of age, was diagnosed with myelodysplastic syndrome and was treated with Arsenic. After drug was administered, patient experienced the following side effects: acute abdomen, chest pain , deep vein thrombosis , disseminated intravascular coagulation, pericardial haemorrhage, pseudomonal sepsis, renal ischaemia. Arsenic dosage: unknown. During the same period patient was treated with FUROSEMIDE, PANTOPRAZOLE, METRONIDAZOLE, PIPERICILLIN, TAZOBACTAM, SELEPARINA. Patient died on 12/13/2007.

Arsenic Side Effects Report #5926641-8
Arsenic side effect was reported by a Health Professional from ITALY on Oct 01, 2008. Male patient was diagnosed with myelodysplastic syndrome and was treated with Arsenic. After drug was administered, patient experienced the following side effects: acute abdomen, deep vein thrombosis , disseminated intravascular coagulation, intestinal ischaemia, pericardial haemorrhage, pseudomonal sepsis, renal ischaemia. Arsenic dosage: unknown. During the same period patient was treated with FUROSEMIDE, PANTOPRAZOLE, METRONIDAZOLE, PIPERICILLIN, TAZOBACTAM, SELEPARINA. Patient was hospitalized. Patient died on 12/13/2007.

Arsenic Side Effects Report #4940793-8
Arsenic side effect was reported by a Physician from JAPAN on Feb 21, 2006. Male patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Arsenic. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, disseminated intravascular coagulation, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Arsenic dosage: 9.3 MG QD INTRAVENOUS DRIP. During the same period patient was treated with NAFAMOSTAT MESILATE. Patient was hospitalized. Patient recovered.

Arsenic Side Effects Report #4909997-4
Arsenic side effect was reported by a Physician from JAPAN on Jan 25, 2006. Male patient, 63 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Arsenic. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, cerebral haemorrhage, disseminated intravascular coagulation, leukaemia recurrent, leukocytosis, loss of consciousness. Arsenic dosage: 7.2 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN. Patient died on 01/11/2006.


Arsenic Side Effects Report #4983246-3
Arsenic side effect was reported by a Physician from JAPAN on Apr 05, 2006. Male patient, 63 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Arsenic. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, blood lactate dehydrogenase increased, cardio-respiratory arrest, cerebral haemorrhage, chest x-ray abnormal, disseminated intravascular coagulation, dyspnoea exertional, leukocytosis, loss of consciousness. Arsenic dosage: 7.2 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN. Patient was hospitalized. Patient died on 01/11/2006.

Arsenic Side Effects Report #4921172-6
Arsenic side effect was reported by a Physician from JAPAN on Feb 06, 2006. Female patient, 41 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Arsenic. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation. Arsenic dosage: unknown. Patient died on 01/28/2006.

Arsenic Side Effects Report #4958089-7
Arsenic side effect was reported by a Physician from JAPAN on Mar 14, 2006. Female patient, 41 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Arsenic. After drug was administered, patient experienced the following side effects: concomitant disease aggravated, disseminated intravascular coagulation, infection . Arsenic dosage: 8.07 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, ENALAPRIL MALEATE, CEFEPIME HYDROCHLORIDE, AMIKACIN SULPHATE, IMIPENEM CILASTATIN. Patient died on 01/28/2006.

Arsenic Side Effects Report #5700267-3
Arsenic side effect was reported by a Health Professional from UNITED STATES on Mar 25, 2008. Female patient, 27 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Arsenic. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, cerebral infarction, cerebrovascular disorder, confusional state, convulsion, disease complication, disseminated intravascular coagulation, dysarthria. Arsenic dosage: 0.15 MG/KG QD INTRAVENOUS. Patient was hospitalized. Patient died.