Arsenic and brain herniation Patient Reports February 12, 2012

Arsenic Side Effects Report #5700267-3
Arsenic side effect was reported by a Health Professional from UNITED STATES on Mar 25, 2008. Female patient, 27 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Arsenic. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, cerebral infarction, cerebrovascular disorder, confusional state, convulsion, disease complication, disseminated intravascular coagulation, dysarthria. Arsenic dosage: 0.15 MG/KG QD INTRAVENOUS. Patient was hospitalized. Patient died.

Arsenic Side Effects Report #5614444-3
Arsenic side effect was reported by a Physician from UNITED KINGDOM on Jan 15, 2008. Female patient, 71 years of age, was diagnosed with acute myeloid leukaemia and was treated with Arsenic. After drug was administered, patient experienced the following side effects: brain herniation, haemoglobin decreased, hydrocephalus , platelet count decreased, subdural haemorrhage, white blood cell count increased. Arsenic dosage: unknown. During the same period patient was treated with CYTARABINE. Patient recovered.

Arsenic Side Effects Report #5646733-0
Arsenic side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 20, 2008. Female patient, 71 years of age, was diagnosed with acute myeloid leukaemia and was treated with Arsenic. After drug was administered, patient experienced the following side effects: brain herniation, haemoglobin decreased, hydrocephalus , platelet count abnormal, subdural haemorrhage, white blood cell count decreased. Arsenic dosage: unknown. During the same period patient was treated with CYTARABINE. Patient recovered.

Arsenic Side Effects Report #5692772-3
Arsenic side effect was reported by a Consumer or non-health professional from FRANCE on Mar 19, 2008. Male patient, 57 years of age, weighting 152.1 lb, was diagnosed with acute myeloid leukaemia and was treated with Arsenic. After drug was administered, patient experienced the following side effects: apallic syndrome, aplasia, blood ph increased, blood pressure systolic increased, brain herniation, cerebral haemorrhage, cholestasis, coma, erythema. Arsenic dosage: 11 MG DAYS 1-5 OF 12 DAY CYCLE QD INTRAVENOUS. During the same period patient was treated with IDARUBICINE, ARACYTINE, PLITICAN, NEXIUM. Patient was hospitalized. Patient died on 11/04/2007.