Argatroban and international normalised ratio increased Patient Reports February 13, 2012

Argatroban Side Effects Report #5574142-1
Argatroban side effect was reported by a Health Professional from UNITED STATES on Dec 11, 2007. Female patient, 49 years of age, was diagnosed with thrombosis prophylaxis and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulation time prolonged, haemoglobin decreased, hypotension, international normalised ratio increased, thrombocytopenia, thrombosis in device. Argatroban dosage: 40 MG, INTRAVENOUS; 10 MG, INTRAVENOUS; 22 MG, INTRAVENOUS. During the same period patient was treated with INSULIN, CALCIUM CHLORIDE, MAGNESIUM SULPHATE, NEO SYNEPHRINE. Patient recovered.

Argatroban Side Effects Report #5914792-3
Argatroban side effect was reported by a Physician from UNITED STATES on Sept 23, 2008. Male patient, 75 years of age, was diagnosed with pulmonary embolism  and was treated with Argatroban. After drug was administered, patient experienced the following side effects: coagulation time prolonged, gastrointestinal haemorrhage, haemoglobin decreased, international normalised ratio increased. Argatroban dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient died.

Argatroban Side Effects Report #4789547-6
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Oct 05, 2005. Male patient, 63 years of age, was diagnosed with prophylaxis and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haematochezia, international normalised ratio increased, rectal haemorrhage. Argatroban dosage: unknown. During the same period patient was treated with WARFARIN, METOPROLOL, TAMSULOSIN, INSULIN SS, FUROSEMIDE, RAMIPRIL, AMIODARONE, RANITIDINE. Patient recovered.

Argatroban Side Effects Report #5946869-0
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Nov 07, 2008. Female patient, 76 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, disseminated intravascular coagulation, international normalised ratio increased, multi-organ failure. Argatroban dosage: unknown. Patient was hospitalized. Patient recovered.


Argatroban Side Effects Report #5363053-2
Argatroban side effect was reported by a Physician from UNITED STATES on June 06, 2007. Female patient, 75 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiac arrest , coagulation time prolonged, finger amputation, foot amputation, gangrene, gastrointestinal haemorrhage, international normalised ratio increased, necrosis ischaemic. Argatroban dosage: unknown. During the same period patient was treated with WARFARIN, HEPARIN, NOREPINEPHRINE. Patient died.

Argatroban Side Effects Report #5320809-X
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Apr 18, 2007. Female patient, 74 years of age, weighting 181.0 lb, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, atrial tachycardia, blood alkaline phosphatase abnormal, gastrointestinal haemorrhage, haematocrit decreased, haemoglobin decreased, international normalised ratio increased, nodal rhythm. Argatroban dosage: unknown. During the same period patient was treated with COUMADIN, ALTACE, PROTONIX. Patient recovered.

Argatroban Side Effects Report #5242823-5
Argatroban side effect was reported by a Physician from UNITED STATES on Jan 25, 2007. Male patient, 65 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, international normalised ratio increased, respiratory failure, sepsis . Argatroban dosage: unknown. During the same period patient was treated with MUCOMYST, VANCOMYCIN, LIPITOR, IRON, NEXIUM, SYNTHROID, CALCITRIOL, FLUCONAZOLE. Patient died on 01/23/2007.

Argatroban Side Effects Report #5168208-8
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Mar 25, 2002. Female patient, 65 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, overdose. Argatroban dosage: 50 MG ONCE IV. During the same period patient was treated with EPOGEN, VERSED, IBUPROFEN, CEFEPIME, INSULIN. Patient recovered.

Argatroban Side Effects Report #5186832-3
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Dec 07, 2006. Female patient, 62 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, hepatic congestion, international normalised ratio increased. Argatroban dosage: unknown. During the same period patient was treated with MILRINONE, COUMADIN, AMIODARONE, ASPIRIN, BUMEX, RISPERDAL, DUONEB. Patient died on 09/06/2006.


Argatroban Side Effects Report #5421168-4
Argatroban side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 09, 2007. Female patient, 32 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased. Argatroban dosage: unknown. During the same period patient was treated with WARFARIN. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5802543-2
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Apr 12, 2007. Male patient was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Argatroban dosage: unknown. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5167063-X
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Oct 23, 2003. Male patient, 54 years of age, weighting 208.3 lb, was diagnosed with continuous haemodiafiltration, heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, epistaxis, injection site haemorrhage, international normalised ratio increased, platelet count decreased. Argatroban dosage: unknown. During the same period patient was treated with ACTIVASE, LACTULOSE, LEVOFLOXACN, RABREPRAZOLE, SALMETEROL, ALBUTEROL. Patient recovered.

Argatroban Side Effects Report #5345137-8
Argatroban side effect was reported by a Pharmacist from UNITED STATES on May 21, 2007. Female patient, 70 years of age, weighting 101.0 lb, was diagnosed with coagulopathy and was treated with Argatroban. After drug was administered, patient experienced the following side effects: coagulation time prolonged, international normalised ratio increased. Argatroban dosage: unknown. During the same period patient was treated with DIGOXIN, ERYTHROPOIETIN, PHENYTOIN, INSULIN, LABETALOL, PREVACID, VERSED. Patient died on 05/18/2007.

Argatroban Side Effects Report #5168179-4
Argatroban side effect was reported by a Pharmacist from UNITED STATES on July 25, 2003. Male patient, 70 years of age, was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulation factor increased, epistaxis, international normalised ratio increased, liver function test abnormal, prothrombin time prolonged. Argatroban dosage: 155 MG CONT IV. Patient recovered.