Argatroban and activated partial thromboplastin time prolonged Patient Reports February 13, 2012

Argatroban Side Effects Report #5777094-4
Argatroban side effect was reported by a Pharmacist from UNITED STATES on June 17, 2008. Male patient, 64 years of age, weighting 189.6 lb, was diagnosed with thrombosis prophylaxis and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood pressure decreased, haemoglobin decreased. Argatroban dosage: unknown. During the same period patient was treated with LORAZEPAM. Patient recovered.

Argatroban Side Effects Report #4999684-9
Argatroban side effect was reported by a Pharmacist from UNITED STATES on May 09, 2006. Female patient, 63 years of age, weighting 244.7 lb, was diagnosed with thrombosis prophylaxis and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, gastrointestinal haemorrhage, haemoglobin decreased. Argatroban dosage: unknown. During the same period patient was treated with INSULIN, LEVOTHYROXINE, SUCRALFATE, NYSTATINE, ZOSYN, HALDOL, VANCOMYCIN. Patient recovered.

Argatroban Side Effects Report #5574142-1
Argatroban side effect was reported by a Health Professional from UNITED STATES on Dec 11, 2007. Female patient, 49 years of age, was diagnosed with thrombosis prophylaxis and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulation time prolonged, haemoglobin decreased, hypotension, international normalised ratio increased, thrombocytopenia, thrombosis in device. Argatroban dosage: 40 MG, INTRAVENOUS; 10 MG, INTRAVENOUS; 22 MG, INTRAVENOUS. During the same period patient was treated with INSULIN, CALCIUM CHLORIDE, MAGNESIUM SULPHATE, NEO SYNEPHRINE. Patient recovered.

Argatroban Side Effects Report #5133802-7
Argatroban side effect was reported by a Physician from UNITED STATES on Oct 02, 2006. Female patient was diagnosed with pulmonary embolism  and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, acute hepatic failure. Argatroban dosage: unknown. Patient was hospitalized. Patient recovered.


Argatroban Side Effects Report #4789547-6
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Oct 05, 2005. Male patient, 63 years of age, was diagnosed with prophylaxis and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haematochezia, international normalised ratio increased, rectal haemorrhage. Argatroban dosage: unknown. During the same period patient was treated with WARFARIN, METOPROLOL, TAMSULOSIN, INSULIN SS, FUROSEMIDE, RAMIPRIL, AMIODARONE, RANITIDINE. Patient recovered.

Argatroban Side Effects Report #5019207-8
Argatroban side effect was reported by a Health Professional from UNITED STATES on May 16, 2006. Female patient, 68 years of age, was diagnosed with myocardial infarction, prophylaxis and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood creatinine increased, blood urea increased, haemodynamic instability, haemorrhage. Argatroban dosage: unknown. Patient was hospitalized. Patient died.

Argatroban Side Effects Report #5229554-2
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Jan 19, 2007. Male patient, 80 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood alkaline phosphatase increased, blood bilirubin increased, international normalised ratio abnormal, prothrombin time prolonged. Argatroban dosage: unknown. During the same period patient was treated with VANCOMYCIN, CLINDAMYCIN, CEFEPIME, TYLENOL, PROCRIT, LEXAPRO, NEPHRO. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5148631-8
Argatroban side effect was reported by a Physician from UNITED STATES on Oct 25, 2006. Male patient, 78 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, activated partial thromboplastin time shortened, burkitt's lymphoma stage iv, metastases to pancreas, renal failure acute. Argatroban dosage: unknown. During the same period patient was treated with DILTIAZEM, NORVASC, PRONTONIX, METOPROLOL, DIGOXIN, LORAZEPAM, VITAMIN K. Patient was hospitalized and became disabled. Patient died on 10/27/2006.

Argatroban Side Effects Report #5946869-0
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Nov 07, 2008. Female patient, 76 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, disseminated intravascular coagulation, international normalised ratio increased, multi-organ failure. Argatroban dosage: unknown. Patient was hospitalized. Patient recovered.


Argatroban Side Effects Report #5363053-2
Argatroban side effect was reported by a Physician from UNITED STATES on June 06, 2007. Female patient, 75 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiac arrest , coagulation time prolonged, finger amputation, foot amputation, gangrene, gastrointestinal haemorrhage, international normalised ratio increased, necrosis ischaemic. Argatroban dosage: unknown. During the same period patient was treated with WARFARIN, HEPARIN, NOREPINEPHRINE. Patient died.

Argatroban Side Effects Report #5167064-1
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Aug 04, 2003. Female patient, 75 years of age, was diagnosed with heparin-induced thrombocytopenia, deep vein thrombosis  and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, deep vein thrombosis , liver disorder, skin necrosis. Argatroban dosage: unknown. During the same period patient was treated with WARFARIN, SPIRONOLACTONE, IRON POLYSACCHARIDE, CEFAPINE, LASIX, ZOCOR, PROTONIX, LISINOPRIL. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5320809-X
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Apr 18, 2007. Female patient, 74 years of age, weighting 181.0 lb, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, atrial tachycardia, blood alkaline phosphatase abnormal, gastrointestinal haemorrhage, haematocrit decreased, haemoglobin decreased, international normalised ratio increased, nodal rhythm. Argatroban dosage: unknown. During the same period patient was treated with COUMADIN, ALTACE, PROTONIX. Patient recovered.

Argatroban Side Effects Report #5961123-9
Argatroban side effect was reported by a Health Professional from JAPAN on Oct 29, 2008. Male patient, 72 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulation time prolonged. Argatroban dosage: unknown. During the same period patient was treated with ALLOPURINOL, FENISTIL, FURORESE, BROMOCRIPTINE, KALINOR, PANTOZOL. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5168208-8
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Mar 25, 2002. Female patient, 65 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, overdose. Argatroban dosage: 50 MG ONCE IV. During the same period patient was treated with EPOGEN, VERSED, IBUPROFEN, CEFEPIME, INSULIN. Patient recovered.


Argatroban Side Effects Report #4730332-9
Argatroban side effect was reported by a Health Professional from JAPAN on July 12, 2005. Male patient, 65 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: accidental overdose, activated partial thromboplastin time prolonged, alanine aminotransferase increased, aspartate aminotransferase increased, coagulopathy, haematochezia, international normalised ratio increased. Argatroban dosage: unknown. During the same period patient was treated with HEPARIN. Patient recovered.

Argatroban Side Effects Report #5186832-3
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Dec 07, 2006. Female patient, 62 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, hepatic congestion, international normalised ratio increased. Argatroban dosage: unknown. During the same period patient was treated with MILRINONE, COUMADIN, AMIODARONE, ASPIRIN, BUMEX, RISPERDAL, DUONEB. Patient died on 09/06/2006.

Argatroban Side Effects Report #5671888-1
Argatroban side effect was reported by a Consumer or non-health professional from JAPAN on Feb 27, 2008. Male patient, 60 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood alkaline phosphatase abnormal, blood bilirubin abnormal, blood lactate dehydrogenase abnormal, gamma-glutamyltransferase abnormal, hepatic function abnormal. Argatroban dosage: unknown. During the same period patient was treated with AMPHOTERICIN B, ANTIBIOTICS. Patient was hospitalized and became disabled. Patient recovered.

Argatroban Side Effects Report #5168176-9
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Feb 13, 2004. Female patient, 57 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, deep vein thrombosis , platelet count decreased. Argatroban dosage: 13 ML CONT IV. During the same period patient was treated with NEURONTIN, GLUCOVANCE, LISINOPRIL, LOPRESSOR, PROTONIX, PREDNISONE, SUCRALFATE, COUMADIN. Patient recovered.

Argatroban Side Effects Report #5346183-0
Argatroban side effect was reported by a Consumer or non-health professional from GERMANY on May 18, 2007. Male patient, 54 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, aspartate aminotransferase increased, blood bilirubin increased, coagulation time prolonged, coagulation time shortened, haemorrhage. Argatroban dosage: unknown. During the same period patient was treated with HEPARIN. Patient died.


Argatroban Side Effects Report #5510685-4
Argatroban side effect was reported by a Physician from UNITED STATES on Oct 24, 2007. Female patient, 54 years of age, weighting 171.1 lb, was diagnosed with heparin-induced thrombocytopenia, fungal infection  and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, prothrombin time prolonged. Argatroban dosage: unknown. During the same period patient was treated with ITRACONAZOLE, AMPHOTERICIN B, OMEPRAZOLE, ALBUTEROL, DOCUSATE, SENNA, INSULIN, CALCIUM CARBONATE. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5392843-5
Argatroban side effect was reported by a Health Professional from GERMANY on July 02, 2007. Male patient, 53 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, activated partial thromboplastin time shortened, aspartate aminotransferase increased, blood bilirubin increased, coagulation time prolonged, haemorrhage, septic shock. Argatroban dosage: unknown. During the same period patient was treated with HEPARIN, ACYCLOVIR, CAPTOPRIL, VIAGRA, DIFLUCAN, ERYTHROMYCIN, VANCOMYCIN, RIFAMPICIN. Patient died on 09/02/2005.

Argatroban Side Effects Report #5731345-0
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Apr 22, 2008. Female patient, 51 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, platelet disorder, thrombosis. Argatroban dosage: unknown. During the same period patient was treated with NORVASC, HYDROMORPHONE, MAGIC MOUTHWASH, GLUCOPHAGE, VITAMIN, NOVOLOG, LANTUS, METAMUCIL. Patient recovered.

Argatroban Side Effects Report #5766141-1
Argatroban side effect was reported by a Health Professional from GERMANY on May 21, 2008. Male patient, 46 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: accidental overdose, activated partial thromboplastin time prolonged, haemodialysis. Argatroban dosage: 2 MG, INTRAVENOUS. Patient recovered.

Argatroban Side Effects Report #5903346-0
Argatroban side effect was reported by a Consumer or non-health professional from JAPAN on Sept 12, 2008. Female patient, 45 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, deep vein thrombosis , gangrene, leg amputation, wound . Argatroban dosage: unknown. During the same period patient was treated with ALPROSTADIL, PREGABALIN, AMITRIPTYLINE HYDROCHLORIDE, PIRITRAMIDE. Patient was hospitalized and became disabled. Patient recovered.


Argatroban Side Effects Report #5354624-8
Argatroban side effect was reported by a Health Professional from GERMANY on May 25, 2007. Male patient, 32 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, aspartate aminotransferase increased, blood bilirubin increased, coagulation time abnormal, thrombin time prolonged. Argatroban dosage: unknown. During the same period patient was treated with HEPARIN. Patient died.

Argatroban Side Effects Report #5421168-4
Argatroban side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 09, 2007. Female patient, 32 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased. Argatroban dosage: unknown. During the same period patient was treated with WARFARIN. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5199650-7
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Jan 03, 2007. Male patient, 24 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardio-respiratory arrest, haematemesis, loss of consciousness, platelet count decreased. Argatroban dosage: unknown. Patient died on 01/01/2007.

Argatroban Side Effects Report #5307785-0
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Apr 02, 2007. Female patient, 22 years of age, weighting 201.5 lb, was diagnosed with heparin-induced thrombocytopenia, urinary tract infection  and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood pressure increased, depressed level of consciousness, heart rate decreased. Argatroban dosage: unknown. During the same period patient was treated with ZYVOX, PEPCID, WARFARIN, IMMUNOGLOBULIN, FRAGMIN. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5146803-X
Argatroban side effect was reported by a Physician from UNITED STATES on Oct 18, 2006. Male patient, 21 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, atelectasis, blood pressure decreased, bronchial haemorrhage, catheter site haemorrhage, chest x-ray abnormal, coagulopathy, deep vein thrombosis , epistaxis. Argatroban dosage: unknown. Patient was hospitalized. Patient recovered.


Argatroban Side Effects Report #4789706-2
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Oct 05, 2005. Male patient was diagnosed with heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, device failure, haematochezia, incorrect dose administered, rectal haemorrhage. Argatroban dosage: 225 MG IV X 1 HR. During the same period patient was treated with DOCUSATE, FLUCONAZOLE, HYDROCORTISONE, LANSOPRAZOLE, LEVOFLOXACIN, MAGNESIUM SULPHATE, METRONIDAZOLE, MONTELUKAST. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5290247-7
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Mar 20, 2007. Male patient, 64 years of age, was diagnosed with deep vein thrombosis , heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, aspartate aminotransferase increased, blood bilirubin increased, condition aggravated, renal failure acute, septic shock. Argatroban dosage: unknown. During the same period patient was treated with LANSOPRAZOL. Patient recovered.

Argatroban Side Effects Report #5167063-X
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Oct 23, 2003. Male patient, 54 years of age, weighting 208.3 lb, was diagnosed with continuous haemodiafiltration, heparin-induced thrombocytopenia and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, epistaxis, injection site haemorrhage, international normalised ratio increased, platelet count decreased. Argatroban dosage: unknown. During the same period patient was treated with ACTIVASE, LACTULOSE, LEVOFLOXACN, RABREPRAZOLE, SALMETEROL, ALBUTEROL. Patient recovered.

Argatroban Side Effects Report #4551937-4
Argatroban side effect was reported by a Health Professional from on Dec 27, 2004. Male patient, 82 years of age, was diagnosed with coronary artery surgery and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, atrial fibrillation , cardiac murmur, endocarditis , lung infection pseudomonal, mass, off label use, post procedural complication, staphylococcal bacteraemia. Argatroban dosage: unknown. During the same period patient was treated with EPINEPHRINE, NOREPINEPHRINE, CEFTAZIDIME. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5168179-4
Argatroban side effect was reported by a Pharmacist from UNITED STATES on July 25, 2003. Male patient, 70 years of age, was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulation factor increased, epistaxis, international normalised ratio increased, liver function test abnormal, prothrombin time prolonged. Argatroban dosage: 155 MG CONT IV. Patient recovered.


Argatroban Side Effects Report #5235394-0
Argatroban side effect was reported by a Pharmacist from UNITED STATES on Feb 08, 2007. Male patient, 59 years of age, weighting 160.1 lb, was diagnosed with heparin-induced thrombocytopenia, sepsis , systemic inflammatory response syndrome and was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardio-respiratory arrest, haemorrhage. Argatroban dosage: unknown. During the same period patient was treated with XIGRIS. Patient died on 01/27/2007.

Argatroban Side Effects Report #5048440-4
Argatroban side effect was reported by a Health Professional from UNITED STATES on June 19, 2006. Female patient was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haemorrhage, infusion site haemorrhage. Argatroban dosage: 250 MG/ML ONCE IV. Patient died.

Argatroban Side Effects Report #5119376-5
Argatroban side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 02, 2006. Female patient was treated with Argatroban. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, catheter site haemorrhage. Argatroban dosage: unknown. Patient recovered.