Arava and hepatic failure Patient Reports February 12, 2012

Arava Side Effects Report #5870797-2
Arava side effect was reported by a Consumer or non-health professional from on Sept 01, 2008. Female patient, 82 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, confusional state, hepatic failure. Arava dosage: unknown. During the same period patient was treated with IMUREL, HEPARIN, ROCEPHIN, CORTANCYL, KARDEGIC, LOPRESSOR, INIPOMP, TAHOR. Patient was hospitalized. Patient recovered.

Arava Side Effects Report #5704267-9
Arava side effect was reported by a Health Professional from PERU on Apr 10, 2008. Male patient, 80 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis b , pneumonia . Arava dosage: unknown. During the same period patient was treated with PREDNISONE, ETORICOXIB, MELOXICAM. Patient died on 02/17/2008.

Arava Side Effects Report #5707204-6
Arava side effect was reported by a Health Professional from PERU on Apr 09, 2008. Male patient, 80 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure, pneumonia . Arava dosage: unknown. Patient was hospitalized. Patient died on 02/17/2008.

Arava Side Effects Report #5733387-8
Arava side effect was reported by a Health Professional from PERU on May 06, 2008. Male patient, 80 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: ascites, hepatic cirrhosis, hepatic encephalopathy, hepatic failure, hepatitis b , hypoalbuminaemia, pleural effusion. Arava dosage: unknown. During the same period patient was treated with PREDNISONE, ETORICOXIB, MELOXICAM. Patient recovered.


Arava Side Effects Report #5737277-6
Arava side effect was reported by a Health Professional from PERU on May 06, 2008. Male patient, 80 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: ascites, hepatic cirrhosis, hepatic encephalopathy, hepatic failure, hepatitis b , hypoalbuminaemia, pleural effusion. Arava dosage: unknown. During the same period patient was treated with PREDNISONE, ETORICOXIB, MELOXICAM. Patient recovered.

Arava Side Effects Report #5604691-9
Arava side effect was reported by a Consumer or non-health professional from on June 28, 2005. Female patient, 75 years of age, was diagnosed with rheumatoid arthritis , hypertension and was treated with Arava. After drug was administered, patient experienced the following side effects: coronary artery disease , gastrointestinal haemorrhage, hepatic failure, renal failure, ulcer . Arava dosage: unknown. During the same period patient was treated with LISINOPRIL, ASPIRIN, ATORVASTATIN, BUDESONIDE, DILTIAZEM, FENTANYL, LANSOPRAZOLE, MIDAZOLAM. Patient died.

Arava Side Effects Report #5627699-6
Arava side effect was reported by a Physician from SPAIN on Feb 06, 2008. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic enzyme increased, hepatic failure, liver disorder, neuropathy peripheral. Arava dosage: unknown. During the same period patient was treated with PARACETAMOL, ADOLONTA, CALCIUM SANDOZTE D, MIACALCIN, OMEPRAZOLE. Patient was hospitalized. Patient died on 02/06/2007.

Arava Side Effects Report #5641067-2
Arava side effect was reported by a Physician from SPAIN on Feb 19, 2008. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic enzyme increased, hepatic failure, liver disorder, neuropathy peripheral. Arava dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, ADOLONTA, CALCIUM SANDOZTE D, MIACALCIN, OMEPRAZOLE. Patient was hospitalized. Patient died on 02/06/2007.

Arava Side Effects Report #5651617-8
Arava side effect was reported by a Physician from SPAIN on Feb 26, 2008. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic enzyme increased, hepatic failure, liver disorder, neuropathy peripheral. Arava dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, ADOLONTA, CALCIUM SANDOZTE D, MIACALCIN, OMEPRAZOLE, RIDAURA, METHOTREXATE. Patient was hospitalized. Patient died on 02/06/2007.


Arava Side Effects Report #5673122-5
Arava side effect was reported by a Physician from SPAIN on Mar 11, 2008. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic enzyme increased, hepatic failure, liver disorder, neuropathy peripheral. Arava dosage: unknown. During the same period patient was treated with PARACETAMOL, ADOLONTA, CALCIUM SANDOZTE D, MIACALCIN, OMEPRAZOLE, RIDAURA, METHOTREXATE. Patient was hospitalized. Patient died on 02/06/2007.

Arava Side Effects Report #5690444-2
Arava side effect was reported by a Physician from SPAIN on Mar 25, 2008. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic enzyme increased, hepatic failure, liver disorder, neuropathy peripheral. Arava dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, ADOLONTA, CALCIUM SANDOZTE D, MIACALCIN, OMEPRAZOLE, RIDAURA, METHOTREXATE. Patient was hospitalized. Patient died on 02/06/2007.

Arava Side Effects Report #5752117-7
Arava side effect was reported by a Physician from SPAIN on May 21, 2008. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis , osteoporosis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic enzyme increased, hepatic failure, neuropathy peripheral. Arava dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, ADOLONTA, CALCIUM SANDOZTE D, MIACALCIN, OMEPRAZOLE, RIDAURA, METHOTREXATE. Patient was hospitalized. Patient died on 02/06/2007.

Arava Side Effects Report #4842566-3
Arava side effect was reported by a Physician from JAPAN on Feb 02, 2004. Female patient, 71 years of age, weighting 116.8 lb, was diagnosed with rheumatoid arthritis , gastritis, hypertension and was treated with Arava. After drug was administered, patient experienced the following side effects: blood potassium increased, blood sodium decreased, cholecystitis chronic, disseminated intravascular coagulation, hepatic failure, interstitial lung disease, liver disorder, melaena. Arava dosage: unknown. During the same period patient was treated with GASTER, MOBIC, DIOVAN, PREDONINE. Patient died on 04/21/2004.

Arava Side Effects Report #5520640-6
Arava side effect was reported by a Physician from GERMANY on Nov 14, 2007. Male patient, 69 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure, liver disorder, pancytopenia. Arava dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient was hospitalized. Patient died on 10/13/2007.


Arava Side Effects Report #4651991-5
Arava side effect was reported by a Consumer or non-health professional from on Apr 26, 2005. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis , asthma , osteoporosis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure, hepatic necrosis, multi-organ failure. Arava dosage: unknown. During the same period patient was treated with PHYLLOCONTIN, FOSAMAX, VENTOLIN HFA, DELTACORTRIL. Patient died on 11/04/2004.

Arava Side Effects Report #4656662-7
Arava side effect was reported by a Consumer or non-health professional from on Apr 26, 2005. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure, hepatic necrosis, multi-organ failure. Arava dosage: 20 MG QD PO. During the same period patient was treated with AMINOPHYLLINE, FOSAMAX, VENTOLIN, PREDNISOLONE. Patient died on 11/04/2004.

Arava Side Effects Report #4699077-8
Arava side effect was reported by a Physician from on May 25, 2005. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis , cellulitis , asthma , osteoporosis , pain  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure. Arava dosage: unknown. During the same period patient was treated with FLUCLOXACILLIN, PREDNISOLONE, ALENDRONATE, DIHYDROCODEINE, AMINOPHYLLINE. Patient died.

Arava Side Effects Report #4799912-9
Arava side effect was reported by a Consumer or non-health professional from on Apr 26, 2005. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis , asthma , osteoporosis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure, hepatic necrosis, multi-organ failure. Arava dosage: unknown. During the same period patient was treated with PHYLLOCONTIN, FOSAMAX, VENTOLIN, DELTACORTRIL. Patient died on 11/04/2004.

Arava Side Effects Report #4813621-9
Arava side effect was reported by a Physician from UNITED KINGDOM on May 25, 2005. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis , cellulitis , asthma , osteoporosis , pain  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure. Arava dosage: unknown. During the same period patient was treated with FLUCLOXACILLIN, PREDNISOLONE, ALENDRONATE, DIHYDROCODEINE, AMINOPHYLLINE. Patient died.


Arava Side Effects Report #4820843-X
Arava side effect was reported by a Physician from UNITED KINGDOM on May 25, 2005. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis , cellulitis , asthma , osteoporosis , pain  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure. Arava dosage: unknown. During the same period patient was treated with FLUCLOXACILLIN, PREDNISOLONE, ALENDRONATE, DIHYDROCODEINE, AMINOPHYLLINE. Patient died.

Arava Side Effects Report #4820844-1
Arava side effect was reported by a Consumer or non-health professional from on Apr 26, 2005. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis , asthma , osteoporosis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure, hepatic necrosis, multi-organ failure. Arava dosage: unknown. During the same period patient was treated with PHYLLOCONTIN, FOSAMAX, VENTOLIN, DELTACORTRIL. Patient died on 11/04/2004.

Arava Side Effects Report #4591744-X
Arava side effect was reported by a Physician from on Feb 23, 2005. Female patient, 56 years of age, weighting 130.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: antinuclear antibody positive, autoimmune hepatitis, encephalopathy, hepatic atrophy, hepatic failure, hepatic necrosis, hepatocellular damage. Arava dosage: 20 MG PO QD. Patient died on 12/19/2004.

Arava Side Effects Report #5393806-6
Arava side effect was reported by a Pharmacist from BRAZIL on July 12, 2007. Female patient, 46 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: diarrhoea, headache , hepatic failure, leukopenia, pain in extremity, pyrexia, sepsis , stevens-johnson syndrome. Arava dosage: unknown. During the same period patient was treated with PREDNISONE. Patient was hospitalized. Patient recovered.

Arava Side Effects Report #5376777-8
Arava side effect was reported by a Consumer or non-health professional from AUSTRALIA on June 27, 2007. Female patient, 43 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure. Arava dosage: unknown. Patient was hospitalized. Patient recovered.


Arava Side Effects Report #4752216-2
Arava side effect was reported by a Pharmacist from UNITED STATES on Aug 15, 2005. Female patient, 27 years of age, was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood bilirubin increased, blood triglycerides increased, bone marrow depression, haemolysis, hepatic failure, mucosal inflammation, pancreatitis, stevens-johnson syndrome. Arava dosage: unknown. Patient was hospitalized. Patient recovered.

Arava Side Effects Report #5700619-1
Arava side effect was reported by a Physician from GERMANY on Apr 05, 2008. Female patient was diagnosed with rheumatoid arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure. Arava dosage: unknown. Patient recovered.

Arava Side Effects Report #4796733-8
Arava side effect was reported by a Physician from GERMANY on Oct 06, 2005. Male patient, 62 years of age, weighting 227.1 lb, was diagnosed with psoriatic arthropathy and was treated with Arava. After drug was administered, patient experienced the following side effects: aphthous stomatitis, candidiasis, cholestasis, circulatory collapse, decubitus ulcer, hepatic failure, procedural complication. Arava dosage: unknown. During the same period patient was treated with CELEBREX, PREDNISOLONE, METHOTREXATE, MORPHINE. Patient was hospitalized. Patient died on 01/22/2004.

Arava Side Effects Report #5682450-9
Arava side effect was reported by a Physician from UNITED STATES on Mar 26, 2008. Female patient, 54 years of age, weighting 175.0 lb, was diagnosed with psoriatic arthropathy, psoriasis and was treated with Arava. After drug was administered, patient experienced the following side effects: coma hepatic, hepatic failure. Arava dosage: 20 MG DAILY PO. During the same period patient was treated with REMICADE. Patient recovered.

Arava Side Effects Report #4602475-1
Arava side effect was reported by a Physician from on Mar 04, 2005. Female patient, 67 years of age, weighting 251.3 lb, was diagnosed with polyarthritis and was treated with Arava. After drug was administered, patient experienced the following side effects: carbohydrate antigen 125 increased, coagulopathy, feeling abnormal, haemolytic anaemia, hepatic failure, hepatic necrosis, oedema peripheral. Arava dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient was hospitalized. Patient died on 12/22/2004.


Arava Side Effects Report #4601166-0
Arava side effect was reported by a Physician from on Mar 10, 2003. Female patient, weighting 103.2 lb, was diagnosed with juvenile arthritis and was treated with Arava. After drug was administered, patient experienced the following side effects: anaemia, cardiac failure, colitis, condition aggravated, electrolyte imbalance, hepatic failure, hypertension, malnutrition, nausea . Arava dosage: unknown. During the same period patient was treated with PROTONIX, METHOTREXATE, IMDUR, OXYCONTIN, OXYCODONE, PEPCID, INDOCIN, PREDNISONE. Patient was hospitalized. Patient died on 08/07/2004.

Arava Side Effects Report #4680813-1
Arava side effect was reported by a Physician from on May 25, 2005. Male patient, 66 years of age, was diagnosed with arthritis  and was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure. Arava dosage: unknown. Patient died.

Arava Side Effects Report #5238246-5
Arava side effect was reported by a Physician from NETHERLANDS on Feb 07, 2007. Female patient, 60 years of age, was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure. Arava dosage: unknown. During the same period patient was treated with REMICADE. Patient was hospitalized. Patient recovered.

Arava Side Effects Report #5280454-1
Arava side effect was reported by a Physician from NETHERLANDS on Mar 23, 2007. Female patient, 60 years of age, was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis toxic. Arava dosage: unknown. During the same period patient was treated with RIVOTRIL, SELOKEEN, INFLIXIMAB. Patient was hospitalized. Patient recovered.

Arava Side Effects Report #5300450-5
Arava side effect was reported by a Physician from NETHERLANDS on Apr 10, 2007. Female patient, 60 years of age, was treated with Arava. After drug was administered, patient experienced the following side effects: abdominal pain , ascites, hepatic failure, hepatitis toxic, jaundice , vomiting. Arava dosage: unknown. During the same period patient was treated with RIVOTRIL, SELOKEEN, INFLIXIMAB. Patient was hospitalized. Patient recovered.


Arava Side Effects Report #5309896-2
Arava side effect was reported by a Physician from NETHERLANDS on Apr 24, 2007. Female patient, 60 years of age, was treated with Arava. After drug was administered, patient experienced the following side effects: abdominal pain , ascites, hepatic failure, hepatitis toxic, jaundice , vomiting. Arava dosage: unknown. During the same period patient was treated with REMICADE, RIVOTRIL, SELOKEEN, LOSEC, ATENOLOL, DICLOFENAC. Patient was hospitalized. Patient recovered.

Arava Side Effects Report #5320044-5
Arava side effect was reported by a Physician from NETHERLANDS on May 03, 2007. Female patient, 60 years of age, weighting 167.6 lb, was treated with Arava. After drug was administered, patient experienced the following side effects: abdominal pain , ascites, hepatic failure, hepatitis toxic, jaundice , vomiting. Arava dosage: unknown. During the same period patient was treated with REMICADE, RIVOTRIL, SELOKEEN, LOSEC, ATENOLOL, DICLOFENAC. Patient was hospitalized. Patient recovered.

Arava Side Effects Report #5578029-X
Arava side effect was reported by a Physician from GERMANY on Dec 27, 2007. Female patient, 60 years of age, weighting 176.4 lb, was diagnosed with immunosuppression, hypertension and was treated with Arava. After drug was administered, patient experienced the following side effects: arthralgia, asthenia, hepatic enzyme increased, hepatic failure. Arava dosage: unknown. During the same period patient was treated with LASIX, SANDIMMUNE, BELOC, ALLOPURINOL. Patient was hospitalized. Patient recovered.

Arava Side Effects Report #5444617-4
Arava side effect was reported by a Physician from UNITED STATES on Apr 06, 2007. Female patient, 13 years of age, was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure, jaundice , pancreatitis. Arava dosage: unknown. During the same period patient was treated with PREDNISONE. Patient was hospitalized. Patient recovered.

Arava Side Effects Report #5600283-6
Arava side effect was reported by a Physician from SPAIN on Jan 15, 2008. Female patient was treated with Arava. After drug was administered, patient experienced the following side effects: hepatic failure, neuropathy peripheral, transaminases increased. Arava dosage: unknown. Patient was hospitalized. Patient died on 01/01/2006.