Ambisome and hypotension Patient Reports February 12, 2012

Ambisome Side Effects Report #4816247-6
Ambisome side effect was reported by a Pharmacist from ITALY on Oct 12, 2005. Female patient, 55 years of age, was diagnosed with systemic mycosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: arrhythmia , hypotension, loss of consciousness. Ambisome dosage: 50.00 MG, UID/QD, IV NOS. Patient recovered.

Ambisome Side Effects Report #5011072-8
Ambisome side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 16, 2006. Female patient, 68 years of age, was diagnosed with systemic candida and was treated with Ambisome. After drug was administered, patient experienced the following side effects: electrocardiogram t wave inversion, hypotension, tachycardia. Ambisome dosage: 1 MG, IV NOS. During the same period patient was treated with PANTOPRAZOLE, HYDROCORTISONE, SALBUTAMOL, IPRATROPIUM BROMIDE, SIMVASTATIN, AUGMENTIN, DALTEPARIN, FUROSEMIDE. Patient recovered.

Ambisome Side Effects Report #5345794-6
Ambisome side effect was reported by a Health Professional from SWEDEN on May 23, 2007. Female patient, 64 years of age, was diagnosed with mycosis fungoides, cytomegalovirus infection  and was treated with Ambisome. After drug was administered, patient experienced the following side effects: fungal sepsis, hypotension. Ambisome dosage: unknown. During the same period patient was treated with GANCICLOVIR, SANDIMMUNE, MERONEM, PRECORTALON AQUOSUM, VANCOMYCIN, URSO FALK. Patient was hospitalized. Patient died on 09/07/2000.

Ambisome Side Effects Report #5911486-5
Ambisome side effect was reported by a Health Professional from UNITED STATES on Sept 19, 2008. Male patient, 28 years of age, was diagnosed with fungal skin infection, candidiasis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: haemodialysis, histoplasmosis disseminated, hypotension, renal failure acute, respiratory distress, tachycardia, trichosporon infection. Ambisome dosage: unknown. During the same period patient was treated with MYCAMINE. Patient was hospitalized. Patient recovered.


Ambisome Side Effects Report #4794989-9
Ambisome side effect was reported by a Physician from GREECE on Sept 21, 2005. Female patient, 23 years of age, was diagnosed with candiduria and was treated with Ambisome. After drug was administered, patient experienced the following side effects: bone marrow toxicity, congestive cardiomyopathy, electrocardiogram st-t change, heart rate increased, hypotension, myocarditis, pancytopenia, pulmonary oedema. Ambisome dosage: 4.00 MG/KG, UID/QD, IV NOS. During the same period patient was treated with CEFTRIAXONE, LEVOFLOXACIN. Patient recovered.

Ambisome Side Effects Report #6054995-3
Ambisome side effect was reported by a Physician from FRANCE on Jan 09, 2009. Male patient, 50 years of age, weighting 282.2 lb, was diagnosed with candidiasis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: bronchospasm, diarrhoea, hypotension, oxygen saturation decreased. Ambisome dosage: 300 MG, UID/QD, IV NOS. During the same period patient was treated with MORPHINE, HEPARIN, ERYTHROMYCIN, TRIFULCAN, VANCOCINE, RIFADINE, PERFALFAN, MOPRAL. Patient was hospitalized. Patient recovered.

Ambisome Side Effects Report #5170646-4
Ambisome side effect was reported by a Consumer or non-health professional from SPAIN on Nov 17, 2006. Female patient, 37 years of age, was diagnosed with candidiasis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac ventricular disorder, cardiomyopathy , dilatation ventricular, ejection fraction decreased, hypotension. Ambisome dosage: 200 MG , UID/QD, IV NOS. Patient recovered.

Ambisome Side Effects Report #4565337-4
Ambisome side effect was reported by a Pharmacist from on Jan 25, 2005. Female patient, 22 years of age, weighting 132.3 lb, was diagnosed with candidiasis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: hypotension, infusion related reaction, oxygen saturation decreased, skin discolouration. Ambisome dosage: 180 MG Q24H INTRAVENOUS. Patient was hospitalized. Patient recovered.

Ambisome Side Effects Report #5510130-9
Ambisome side effect was reported by a Physician from JAPAN on Oct 19, 2007. Male patient, 79 years of age, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: anaemia, c-reactive protein increased, hypoalbuminaemia, hypotension, platelet count decreased, pulmonary oedema, respiratory failure, white blood cell count decreased. Ambisome dosage: 100 MG, UID/QD, IV DRIP. During the same period patient was treated with SOLDEM, NOVO HEPARIN, OMEGACIN, AMINO ACIDS, OMEPRAL, PROPOFOL. Patient recovered.


Ambisome Side Effects Report #5525067-9
Ambisome side effect was reported by a Physician from JAPAN on Nov 08, 2007. Male patient, 79 years of age, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: anaemia, hypoalbuminaemia, hypotension, no therapeutic response, platelet count decreased, pulmonary oedema, respiratory failure, white blood cell count decreased. Ambisome dosage: 100 MG, UID/QD, IV DRIP. During the same period patient was treated with SOLDEM, NOVO HEPARIN, OMEGACIN, AMINO ACIDS, OMEPRAL, PROPOFOL, DOBUTAMINE. Patient died on 08/07/2007.

Ambisome Side Effects Report #5613345-4
Ambisome side effect was reported by a Physician from JAPAN on Jan 17, 2008. Male patient, 79 years of age, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: anaemia, bronchopulmonary aspergillosis, disseminated intravascular coagulation, hypoalbuminaemia, hypotension, platelet count decreased, pulmonary oedema, respiratory failure, staphylococcal sepsis. Ambisome dosage: 100 MG, UID/QD;IV DRIP. During the same period patient was treated with SOLDEM, NOVO HEPARIN, OMEGACIN, AMINO ACIDS, OMEPRAL, PROPOFOL, DOBUTAMINE. Patient died on 08/07/2007.

Ambisome Side Effects Report #5513674-9
Ambisome side effect was reported by a Physician from TURKEY on Oct 25, 2007. Female patient, 33 years of age, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: acute respiratory failure, atrioventricular block complete, bronchopulmonary aspergillosis, cardio-respiratory arrest, cardiotoxicity, haemoptysis, hypotension, infusion related reaction, pyrexia. Ambisome dosage: unknown. During the same period patient was treated with AMIKACIN SULPHATE, LEVONORGESTREL, MEROPENEM, LANSOPRAZOLE, ITRACONAZOLE. Patient died.

Ambisome Side Effects Report #5759318-2
Ambisome side effect was reported by a Health Professional from JAPAN on May 07, 2008. Male patient, 60 years of age, weighting 114.6 lb, was diagnosed with brain abscess, lymphoma  and was treated with Ambisome. After drug was administered, patient experienced the following side effects: central nervous system lymphoma, depressed level of consciousness, dysphagia, hypotension, liver disorder. Ambisome dosage: 150 MG, UID/QD, APPROX 28.7MG/KG. During the same period patient was treated with MEROPENEM TRIHYDRATE, VANCOMYCIN HYDROCHLORIDE, ANCOTIL, FAMOTIDINE, ENTERONON R, TEGRETOL, PROMAC, LOXONIN. Patient died on 08/26/2007.

Ambisome Side Effects Report #5827695-X
Ambisome side effect was reported by a Health Professional from JAPAN on July 10, 2008. Male patient, 60 years of age, weighting 114.6 lb, was diagnosed with brain abscess, lymphoma  and was treated with Ambisome. After drug was administered, patient experienced the following side effects: brain cancer metastatic, central nervous system lymphoma, dysphagia, hypotension, liver disorder. Ambisome dosage: 150 MG, UID/QD, APPROX 28.7MG/KG. During the same period patient was treated with MEROPENEM TRIHYDRATE, VANCOMYCIN HYDROCHLORIDE, ANCOTIL, FAMOTIDINE, ENTERONON R, TEGRETOL, PROMAC, LOXONIN. Patient died on 08/21/2007.


Ambisome Side Effects Report #5909752-2
Ambisome side effect was reported by a Health Professional from JAPAN on July 10, 2008. Male patient, 60 years of age, weighting 114.6 lb, was diagnosed with brain abscess, lymphoma  and was treated with Ambisome. After drug was administered, patient experienced the following side effects: brain neoplasm malignant, depressed level of consciousness, dysphagia, hypotension, liver disorder. Ambisome dosage: 150 MG, UID/QD, APPROX 28.7MG/KG, IV NOS. During the same period patient was treated with MEROPENEM TRIHYDRATE, VANCOMYCIN HYDROCHLORIDE, ANCOTIL, GASTER D, ENTERONON R, TEGRETOL, PROMAC, LOXONIN. Patient died on 08/21/2007.

Ambisome Side Effects Report #5526168-1
Ambisome side effect was reported by a Health Professional from ITALY on Oct 16, 2007. Female patient, 43 years of age, weighting 249.1 lb, was diagnosed with antifungal prophylaxis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: acidosis, agitation, aplasia, continuous haemodiafiltration, fluid overload, hypokalaemia, hypotension, incorrect dose administered, laboratory test abnormal. Ambisome dosage: 3 MG/KG, Q3D,. During the same period patient was treated with RASBURICASE, HYDROXYUREA, OMEPRAZOLE, ACYCLOVIR, POTASSIUM CHLORIDE, SALINEX, BICARBONAT, ALLOPURINOL. Patient recovered.

Ambisome Side Effects Report #5546794-3
Ambisome side effect was reported by a Health Professional from ITALY on Nov 06, 2007. Female patient, 43 years of age, weighting 249.1 lb, was diagnosed with antifungal prophylaxis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: anuria, atrial fibrillation , fluid overload, haemodialysis, hypotension, leukaemia, nephropathy toxic, no therapeutic response, pain . Ambisome dosage: 3 MG/KG, Q3D. During the same period patient was treated with RASBURICASE, HYDROXYUREA, OMEPRAZOLE, ACYCLOVIR, POTASSIUM CHLORIDE, SALINEX, BICARBONAT, ALLOPURINOL. Patient recovered.

Ambisome Side Effects Report #5345797-1
Ambisome side effect was reported by a Health Professional from SWEDEN on May 23, 2007. Male patient, 61 years of age, was treated with Ambisome. After drug was administered, patient experienced the following side effects: cholangitis, complications of transplanted liver, condition aggravated, hepatic failure, hepatic ischaemia, hypotension, metabolic acidosis, transplant failure. Ambisome dosage: unknown. During the same period patient was treated with GANCICLOVIR, URSO FALK, PROGRAF, MERONEM, PREDNISOLONE, CEFTAZIDIME, LOSEC, VANCOMYCIN HYDROCHLORIDE. Patient was hospitalized. Patient died on 10/26/2000.

Ambisome Side Effects Report #4557279-5
Ambisome side effect was reported by a Physician from on Jan 10, 2005. Male patient, child 3 years of age, weighting 26.46 lb, was treated with Ambisome. After drug was administered, patient experienced the following side effects: hypotension, metabolic acidosis, peripheral circulatory failure, ventricular tachycardia. Ambisome dosage: 5.00 MG/KG, INTRAVENOUS. During the same period patient was treated with VANCOMYCIN, RIFAMPICIN, AMIKACIN. Patient died on 12/25/2004.


Ambisome Side Effects Report #5361128-5
Ambisome side effect was reported by a Consumer or non-health professional from ITALY on May 30, 2007. Female patient, 25 years of age, was treated with Ambisome. After drug was administered, patient experienced the following side effects: dyspnoea, erythema, hyperhidrosis, hypotension, lung infection, oxygen saturation decreased, pallor. Ambisome dosage: 50 MG. Patient was hospitalized. Patient recovered.

Ambisome Side Effects Report #5361918-9
Ambisome side effect was reported by a Consumer or non-health professional from ITALY on May 30, 2007. Female patient, 25 years of age, was treated with Ambisome. After drug was administered, patient experienced the following side effects: dyspnoea, erythema, hyperhidrosis, hypotension, lung infection, oxygen saturation decreased, pallor. Ambisome dosage: 50 MG. Patient was hospitalized. Patient recovered.