Ambisome and cardiac failure Patient Reports February 12, 2012

Ambisome Side Effects Report #5346700-0
Ambisome side effect was reported by a Consumer or non-health professional from JAPAN on May 17, 2007. Female patient, 92 years of age, was diagnosed with meningitis cryptococcal and was treated with Ambisome. After drug was administered, patient experienced the following side effects: blood albumin increased, cardiac failure, mitral valve incompetence, renal impairment, tricuspid valve incompetence, urinary tract infection . Ambisome dosage: 135 MG, UID/QD. During the same period patient was treated with MEROPENEM TRIHYDRATE, MEROPENEM TRIHYDRATE, FIRSTCIN, MUCOSTA, LANSOPRAZOLE, LAC B, MAGMITT, CALONAL. Patient died on 01/27/2007.

Ambisome Side Effects Report #5348436-9
Ambisome side effect was reported by a Consumer or non-health professional from JAPAN on May 24, 2007. Female patient, 92 years of age, was diagnosed with meningitis cryptococcal and was treated with Ambisome. After drug was administered, patient experienced the following side effects: blood albumin decreased, cardiac failure, malnutrition, mitral valve incompetence, renal impairment, tricuspid valve incompetence, urinary tract infection . Ambisome dosage: 135 MG, UID/QD, INT CORP CAVER. During the same period patient was treated with MEROPENEM TRIHYDRATE, MEROPENEM TRIHYDRATE, FIRSTCIN, MUCOSTA, LANSOPRAZOLE, LAC B, MAGMITT, CALONAL. Patient died on 01/27/2007.

Ambisome Side Effects Report #5245887-8
Ambisome side effect was reported by a Pharmacist from UNITED STATES on Feb 06, 2007. Female patient, 54 years of age, weighting 141.1 lb, was diagnosed with laryngitis bacterial and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac failure, cardiogenic shock, congestive cardiomyopathy, cryptococcosis, hyperhidrosis, laryngitis, mental status changes, nausea , pathogen resistance. Ambisome dosage: 5 MG/KG, UID/QD, IV NOS. During the same period patient was treated with FLUCYTOSINE, IMIPRAMINE, ESCITALOPRAM OXALATE, BACLOFEN, ACYCLOVIR, ESOMEPRAZOLE, CETIRIZNE, TOLTERODINE TARTRATE. Patient was hospitalized. Patient recovered.

Ambisome Side Effects Report #5810761-2
Ambisome side effect was reported by a Pharmacist from UNITED STATES on June 26, 2008. Female patient, 54 years of age, weighting 141.1 lb, was diagnosed with laryngitis bacterial and was treated with Ambisome. After drug was administered, patient experienced the following side effects: angiopathy, cardiac failure, cardiogenic shock, congestive cardiomyopathy, hyperhidrosis, mental status changes, myocardial infarction, nausea , pleural effusion. Ambisome dosage: 5 MG/KG, UID/QD, IV NOS. During the same period patient was treated with FLUCYTOSINE, IMIPRAMINE, ESCITALOPRAM OXALATE, BACLOFEN, ACYCLOVIR, ESOMEPRAZOLE MAGNESIUM, CETIRIZINE, TOLTERODINE TARTRATE. Patient was hospitalized. Patient recovered.


Ambisome Side Effects Report #5531375-8
Ambisome side effect was reported by a Physician from JAPAN on Nov 14, 2007. Male patient, 85 years of age, was diagnosed with fungal infection  and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac failure. Ambisome dosage: 100 MG, UID/QD, IV NOS. Patient died on 10/24/2007.

Ambisome Side Effects Report #6025529-4
Ambisome side effect was reported by a Health Professional from JAPAN on Dec 19, 2008. Female patient, 82 years of age, weighting 104.1 lb, was diagnosed with fungal infection  and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac failure, disorientation, hyperglycaemia. Ambisome dosage: 100 MG, UID/QD, IV DRIP. During the same period patient was treated with MEROPEN, VANCOMYCIN HYDROCHLORIDE, OMEGACIN, ADONA, GASMOTIN, SIGMART, CIPROFLOXACIN, DEPAS. Patient recovered.

Ambisome Side Effects Report #6054994-1
Ambisome side effect was reported by a Health Professional from JAPAN on Jan 09, 2009. Female patient, 82 years of age, weighting 104.1 lb, was diagnosed with fungal infection  and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac failure, disorientation, hyperglycaemia. Ambisome dosage: 100 MG UID/QD, IV DRIP. During the same period patient was treated with MEROPENEM, VANCOMYCIN HYDROCHLORIDE, OMEGACIN, ADONA, GASMOTIN, SIGMART, CIPROFLOXACIN, DEPAS. Patient recovered.

Ambisome Side Effects Report #6088562-2
Ambisome side effect was reported by a Physician from JAPAN on Feb 10, 2009. Female patient, 82 years of age, weighting 104.1 lb, was diagnosed with fungal infection  and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac failure, disorientation, hyperglycaemia, sepsis . Ambisome dosage: 100 MG, UID/QD, IV DRIP. During the same period patient was treated with MEROPEN, VANCOMYCIN HYDROCHLORIDE, OMEGACIN, ADONA, GASMOTIN, SIGMART, CIPROFLOXACIN, DEPAS. Patient died on 01/02/2008.

Ambisome Side Effects Report #5689774-X
Ambisome side effect was reported by a Health Professional from PORTUGAL on Mar 12, 2008. Female patient, 51 years of age, was diagnosed with candidiasis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac failure, hyperkalaemia. Ambisome dosage: 300 MG, UID/QD, IV NOS. During the same period patient was treated with VALPROATE, VALPROIC ACID, PANTOPRAZOLE, THIOPENTAL, DOMPERIDONE, SUCRALFATE, TOPIRAMATE, PARACETAMOL. Patient recovered.


Ambisome Side Effects Report #5828243-0
Ambisome side effect was reported by a Health Professional from SWEDEN on July 15, 2008. Female patient was diagnosed with candida sepsis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac failure, myocarditis, ventricular septal defect. Ambisome dosage: 5.6 MG, UID/QD,. During the same period patient was treated with CANCIDAS, NEUPOGEN, VANCOMYCIN, FUROSEMIDE, MERONEM, FLUCONAZOLE, RIFAMPICIN, FLAGYL. Patient died on 12/20/2007.

Ambisome Side Effects Report #5917951-9
Ambisome side effect was reported by a Health Professional from SWEDEN on Sept 24, 2008. Female patient, weighting 1.32 lb, was diagnosed with candida sepsis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac failure, myocarditis, neutropenia, ventricular septal defect. Ambisome dosage: 5.6 MG, UID/QD : 2 MG/ML, IV NOS. During the same period patient was treated with CANCIDAS, NEUPOGEN, VANCOMYCIN, FUROSEMIDE, MERONEM, FLUCONAZOLE, RIFAMPICIN, FLAGYL. Patient died on 12/20/2007.

Ambisome Side Effects Report #5567378-7
Ambisome side effect was reported by a Physician from JAPAN on Nov 28, 2007. Male patient, 79 years of age, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: anaemia, bacteria sputum identified, beta haemolytic streptococcal infection, bronchopulmonary aspergillosis, cardiac failure, corynebacterium infection, disseminated intravascular coagulation, fungus sputum test positive, hypoalbuminaemia. Ambisome dosage: 100 MG. During the same period patient was treated with SOLDEM. Patient died on 08/07/2007.

Ambisome Side Effects Report #5641967-3
Ambisome side effect was reported by a Health Professional from JAPAN on Feb 08, 2008. Male patient, 73 years of age, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: blood creatinine increased, cardiac failure. Ambisome dosage: 150 MG, UID/QD, IV NOS. During the same period patient was treated with OMEGACIN, AMINOTRIPA, ALTAT, MULTAMIN, DOPAMINE HYDROCHLORIDE, DOBUTREX, HUMULIN R, MEROPEN. Patient died on 07/02/2007.

Ambisome Side Effects Report #5663913-9
Ambisome side effect was reported by a Health Professional from JAPAN on Feb 27, 2008. Male patient, 73 years of age, weighting 143.7 lb, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: blood creatinine increased, cardiac failure. Ambisome dosage: 150 MG, UID/QD, IV NOS. During the same period patient was treated with OMEGACIN, AMINOTRIPA, ALTAT, MULTAMIN, DOPAMINE HYDROCHLORIDE, DOBUTREX, HUMULIN R, MEROPEN. Patient died on 07/02/2007.


Ambisome Side Effects Report #6032067-1
Ambisome side effect was reported by a Physician from JAPAN on Dec 26, 2008. Male patient, 66 years of age, weighting 100.5 lb, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: arrhythmia , cardiac failure, pneumonia , upper gastrointestinal haemorrhage. Ambisome dosage: 100 MG/KG UID/QD IV NOS. During the same period patient was treated with CLARITHROMYCIN, MAGMITT, ALOSENN, VFEND, UNASYN, DALACIN ST, OMEGACIN, OMEPRAL. Patient died on 08/08/2008.

Ambisome Side Effects Report #5527625-4
Ambisome side effect was reported by a Health Professional from JAPAN on Nov 06, 2007. Male patient, 47 years of age, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac failure, hypokalaemia. Ambisome dosage: 150 MG, UID/QD, IV NOS; 300 MG, UID/QD, IV NOS. During the same period patient was treated with MEROPEN, VANCOMYCIN HYDROCHLORIDE, LANSOPRAZOLE, RED BLOOD CELLS, VFEND, PAZUFLOXACIN, ARBEKACIN. Patient recovered.

Ambisome Side Effects Report #5988797-0
Ambisome side effect was reported by a Health Professional from JAPAN on Nov 19, 2008. Male patient, 47 years of age, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: cardiac failure, hypokalaemia. Ambisome dosage: 150 MG, UID/QD, IV NOS; 300 MG, UID/QD, IV NOS. During the same period patient was treated with PAZUFLOXACIN, CHLORIDE, ARBEKACIN, MEROPEN, VANCOMYCIN HYDROCHLORIDE, LANSOPRAZOLE, RED BLOOD CELLS. Patient recovered.

Ambisome Side Effects Report #5800893-7
Ambisome side effect was reported by a Physician from JAPAN on June 18, 2008. Male patient, 25 years of age, weighting 112.4 lb, was diagnosed with bronchopulmonary aspergillosis and was treated with Ambisome. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, cardiac failure, condition aggravated, deep vein thrombosis , disease complication, hiccups. Ambisome dosage: 250 MG, UID/QD, IV NOS. During the same period patient was treated with FUNGIZONE, CARBENIN, CYTARABINE, VEPESODE, METHOTREXATE, DECADRON. Patient was hospitalized. Patient recovered.