Amantadine and inappropriate antidiuretic hormone secretion Patient Reports February 12, 2012

Amantadine Side Effects Report #5377695-1
Amantadine side effect was reported by a Consumer or non-health professional from on July 03, 2007. Male patient, child 11 years of age, was diagnosed with rabies  and was treated with Amantadine. After drug was administered, patient experienced the following side effects: atrioventricular block, autonomic nervous system imbalance, brain oedema, cerebrovascular spasm, convulsion, diabetes insipidus , inappropriate antidiuretic hormone secretion, pancreatic enzymes increased. Amantadine dosage: unknown. During the same period patient was treated with MIDAZOLAM, KETAMINE, RIBAVIRIN, TETRAHYDROBIOPTERIN, COENZYME Q. Patient died on 12/13/2006.

Amantadine Side Effects Report #5377693-8
Amantadine side effect was reported by a Consumer or non-health professional from on July 02, 2007. Female patient, child 10 years of age, was diagnosed with rabies  and was treated with Amantadine. After drug was administered, patient experienced the following side effects: brain herniation, diabetes insipidus , inappropriate antidiuretic hormone secretion, intracranial pressure increased, intracranial venous sinus thrombosis, pancreatitis. Amantadine dosage: unknown. During the same period patient was treated with MIDAZOLAM, ASCORBIC ACID, PHENOBARBITAL, KETAMINE, RIBAVIRIN, COENZYME Q, TETRAHYDROBIOPTERIN. Patient died on 11/02/2006.

Amantadine Side Effects Report #5840662-5
Amantadine side effect was reported by a Health Professional from SPAIN on Aug 04, 2008. Female patient, 66 years of age, was diagnosed with parkinson's disease  and was treated with Amantadine. After drug was administered, patient experienced the following side effects: anorexia, asthenia, blood sodium increased, inappropriate antidiuretic hormone secretion, lethargy, muscular weakness, urine sodium decreased, weight decreased. Amantadine dosage: 100 MG, BID. During the same period patient was treated with ENTACAPONE, CARBIDOPA, CABERGOLINE. Patient recovered.