Alkeran and venoocclusive liver disease Patient Reports February 11, 2012

Alkeran Side Effects Report #5190023-X
Alkeran side effect was reported by a Physician from JAPAN on Dec 05, 2006. Male patient, child 7 years of age, was diagnosed with stem cell transplant and was treated with Alkeran. After drug was administered, patient experienced the following side effects: anal stenosis, febrile neutropenia, mucous membrane disorder, venoocclusive liver disease. Alkeran dosage: 70 MG/M2 / PER DAY / INTRAVENOUS. During the same period patient was treated with THIOTEPA. Patient recovered.

Alkeran Side Effects Report #4996200-2
Alkeran side effect was reported by a Physician from JAPAN on Apr 20, 2006. Female patient, child 5 years of age, was diagnosed with stem cell transplant and was treated with Alkeran. After drug was administered, patient experienced the following side effects: ascites, fibrin d dimer increased, hepatomegaly, protein c decreased, thrombocytopenia, venoocclusive liver disease, weight increased. Alkeran dosage: 70 MG/M2/ D. During the same period patient was treated with BUSULPHAN, VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, COLASPASE, CYCLOSPORINE, METHOTREXATE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5856286-X
Alkeran side effect was reported by a Physician from JAPAN on Aug 21, 2008. Female patient, 23 years of age, weighting 121.3 lb, was diagnosed with stem cell transplant and was treated with Alkeran. After drug was administered, patient experienced the following side effects: abdominal pain , ascites, hepatomegaly, liver disorder, renal failure, venoocclusive liver disease, weight increased. Alkeran dosage: unknown. During the same period patient was treated with FLUDARA, METHOTREXATE, PROGRAF, CRAVIT, DIFLUCAN, URSO, ZOVIRAX, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #4714406-4
Alkeran side effect was reported by a Consumer or non-health professional from FRANCE on July 06, 2005. Female patient, child 5 years of age, weighting 35.27 lb, was diagnosed with medulloblastoma and was treated with Alkeran. After drug was administered, patient experienced the following side effects: abdominal pain , alanine aminotransferase increased, aspartate aminotransferase increased, headache , transaminases increased, venoocclusive liver disease. Alkeran dosage: 5MGML CYCLIC. Patient was hospitalized. Patient recovered.


Alkeran Side Effects Report #4735638-5
Alkeran side effect was reported by a Consumer or non-health professional from FRANCE on July 06, 2005. Female patient, child 5 years of age, weighting 35.27 lb, was diagnosed with medulloblastoma and was treated with Alkeran. After drug was administered, patient experienced the following side effects: abdominal pain , headache , hepatitis , peritoneal effusion, transaminases increased, venoocclusive liver disease. Alkeran dosage: 5MGML CYCLIC. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5946522-3
Alkeran side effect was reported by a Consumer or non-health professional from JAPAN on Nov 05, 2008. Male patient, child 2 years of age, was diagnosed with bone marrow transplant  and was treated with Alkeran. After drug was administered, patient experienced the following side effects: pulmonary haemorrhage, renal failure, venoocclusive liver disease. Alkeran dosage: unknown. During the same period patient was treated with CARBOPLATIN, ETOPOSIDE. Patient died.

Alkeran Side Effects Report #5961560-2
Alkeran side effect was reported by a Physician from JAPAN on Nov 13, 2008. Male patient, child 2 years of age, was diagnosed with bone marrow transplant  and was treated with Alkeran. After drug was administered, patient experienced the following side effects: pulmonary haemorrhage, renal failure, venoocclusive liver disease. Alkeran dosage: unknown. During the same period patient was treated with CARBOPLATIN, ETOPOSIDE. Patient died.

Alkeran Side Effects Report #5296220-7
Alkeran side effect was reported by a Consumer or non-health professional from FRANCE on Apr 04, 2007. Female patient, child 1 years of age, was diagnosed with bone marrow transplant  and was treated with Alkeran. After drug was administered, patient experienced the following side effects: anuria, ascites, blood bilirubin increased, oliguria, venoocclusive liver disease, weight increased. Alkeran dosage: unknown. During the same period patient was treated with ENDOXAN, BUSULFAN, CYCLOSPORINE, CORTICOIDS. Patient recovered.

Alkeran Side Effects Report #6013751-2
Alkeran side effect was reported by a Consumer or non-health professional from FRANCE on Dec 10, 2008. Female patient, weighting 24.25 lb, was diagnosed with bone marrow transplant  and was treated with Alkeran. After drug was administered, patient experienced the following side effects: hepatocellular injury, hepatomegaly, mucosal inflammation, oedema peripheral, venoocclusive liver disease, weight increased. Alkeran dosage: 70MG SINGLE DOSE. During the same period patient was treated with BUSULPHAN. Patient was hospitalized. Patient recovered.


Alkeran Side Effects Report #5156310-6
Alkeran side effect was reported by a Physician from JAPAN on Jan 27, 2006. Male patient, child 6 years of age, was treated with Alkeran. After drug was administered, patient experienced the following side effects: febrile neutropenia, hepatic vein occlusion, mucous membrane disorder, recurrent cancer, venoocclusive liver disease. Alkeran dosage: unknown. During the same period patient was treated with THIOTEPA. Patient died on 12/01/2004.

Alkeran Side Effects Report #5607995-9
Alkeran side effect was reported by a Physician from JAPAN on Jan 21, 2008. Male patient, 53 years of age, weighting 123.5 lb, was diagnosed with immunosuppression and was treated with Alkeran. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, melaena, renal failure acute, toxic encephalopathy, venoocclusive liver disease. Alkeran dosage: 140MGM2 PER DAY. During the same period patient was treated with CYCLOSPORINE, METHYLPREDNISOLONE, ISCOTIN, LOMEFLOXACIN, NYSTATIN, URSO, ZOVIRAX. Patient was hospitalized. Patient died on 05/29/2007.

Alkeran Side Effects Report #4854758-8
Alkeran side effect was reported by a Consumer or non-health professional from JAPAN on Dec 06, 2005. Female patient, 18 years of age, was treated with Alkeran. After drug was administered, patient experienced the following side effects: mucous membrane disorder, sepsis , venoocclusive liver disease. Alkeran dosage: unknown. Patient recovered.

Alkeran Side Effects Report #4854759-X
Alkeran side effect was reported by a Consumer or non-health professional from JAPAN on Dec 06, 2005. Male patient, 18 years of age, was treated with Alkeran. After drug was administered, patient experienced the following side effects: mucous membrane disorder, venoocclusive liver disease. Alkeran dosage: unknown. Patient recovered.

Alkeran Side Effects Report #5987022-4
Alkeran side effect was reported by a Physician from JAPAN on Dec 01, 2008. Female patient, 14 years of age, was treated with Alkeran. After drug was administered, patient experienced the following side effects: diarrhoea, mucous membrane disorder, stomatitis, venoocclusive liver disease. Alkeran dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, TACROLIMUS. Patient was hospitalized. Patient recovered.


Alkeran Side Effects Report #6027334-1
Alkeran side effect was reported by a Physician from JAPAN on Dec 29, 2008. Female patient, 14 years of age, was diagnosed with prophylaxis against graft versus host disease, stomatitis and was treated with Alkeran. After drug was administered, patient experienced the following side effects: diarrhoea, mucous membrane disorder, stomatitis, venoocclusive liver disease. Alkeran dosage: 50MGM2 PER DAY. During the same period patient was treated with FLUDARA, METHOTREXATE, PROGRAF, ELASE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5946523-5
Alkeran side effect was reported by a Consumer or non-health professional from JAPAN on Nov 05, 2008. Female patient, child 1 years of age, was diagnosed with stem cell transplant and was treated with Alkeran. After drug was administered, patient experienced the following side effects: renal failure, thrombotic microangiopathy, venoocclusive liver disease. Alkeran dosage: unknown. During the same period patient was treated with CARBOPLATIN, ETOPOSIDE. Patient died.

Alkeran Side Effects Report #5961561-4
Alkeran side effect was reported by a Physician from JAPAN on Nov 13, 2008. Female patient, child 1 years of age, was diagnosed with stem cell transplant and was treated with Alkeran. After drug was administered, patient experienced the following side effects: renal failure, thrombotic microangiopathy, venoocclusive liver disease. Alkeran dosage: unknown. During the same period patient was treated with CARBOPLATIN, ETOPOSIDE. Patient died.