Alkeran and bone marrow failure Patient Reports February 11, 2012

Alkeran Side Effects Report #5819196-X
Alkeran side effect was reported by a Physician from THAILAND on July 16, 2008. Female patient, 56 years of age, was diagnosed with stem cell transplant and was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, mucosal inflammation, nausea . Alkeran dosage: 100MG PER DAY. Patient died.

Alkeran Side Effects Report #5819194-6
Alkeran side effect was reported by a Physician from THAILAND on July 16, 2008. Male patient, 48 years of age, was diagnosed with stem cell transplant and was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, mucosal inflammation, nausea . Alkeran dosage: 300MG PER DAY. Patient recovered.

Alkeran Side Effects Report #5292139-6
Alkeran side effect was reported by a Health Professional from CANADA on Apr 04, 2007. Male patient, 42 years of age, weighting 229.3 lb, was diagnosed with stem cell transplant, stomatitis and was treated with Alkeran. After drug was administered, patient experienced the following side effects: abdominal discomfort, bone marrow failure, clostridium difficile colitis, delayed engraftment, febrile neutropenia, gastrointestinal necrosis, hypotension, impaired healing, international normalised ratio increased. Alkeran dosage: unknown. During the same period patient was treated with KEPIVANCE, ETOPOSIDE, ONDANSETRON, DEXAMETHASONE, DOMPERIDONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5313820-6
Alkeran side effect was reported by a Health Professional from CANADA on Apr 27, 2007. Male patient, 42 years of age, weighting 229.3 lb, was diagnosed with stem cell transplant, stomatitis and was treated with Alkeran. After drug was administered, patient experienced the following side effects: abdominal discomfort, bone marrow failure, clostridium difficile colitis, delayed engraftment, febrile neutropenia, gastrointestinal necrosis, hypotension, impaired healing, international normalised ratio increased. Alkeran dosage: unknown. During the same period patient was treated with KEPIVANCE, ETOPOSIDE, ONDANSETRON, DEXAMETHASONE, DOMPERIDONE. Patient was hospitalized. Patient recovered.


Alkeran Side Effects Report #5303311-0
Alkeran side effect was reported by a Physician from JAPAN on Apr 16, 2007. Male patient, child 1 years of age, weighting 20.94 lb, was diagnosed with stem cell transplant and was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, febrile neutropenia, sepsis . Alkeran dosage: 31MG PER DAY. During the same period patient was treated with THIOTEPA, PHENOBARBITAL, BAKTAR, DIFLUCAN, POLYMYXIN B SULPHATE, ZOVIRAX. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #4794286-1
Alkeran side effect was reported by a Consumer or non-health professional from FRANCE on Sept 29, 2005. Male patient, 67 years of age, weighting 136.7 lb, was diagnosed with multiple myeloma  and was treated with Alkeran. After drug was administered, patient experienced the following side effects: acute pulmonary oedema, aplasia, atrial fibrillation , bone marrow failure, cardiac failure, diarrhoea, dyspnoea, fluid retention. Alkeran dosage: 340MG PER DAY. During the same period patient was treated with NEUPOGEN, VFEND, VELCADE, ORAL BOWEL DECONTAMINATION SOLUTION, FLUCONAZOLE, AMPHOTERICIN B, VANCOMYCIN. Patient recovered.

Alkeran Side Effects Report #5254280-3
Alkeran side effect was reported by a Consumer or non-health professional from FRANCE on Feb 19, 2007. Male patient, 61 years of age, was diagnosed with multiple myeloma  and was treated with Alkeran. After drug was administered, patient experienced the following side effects: acidosis, bone marrow failure, bronchial obstruction, cardiac failure, confusional state, dyspnoea, hypercapnia, hypoxia, inflammation. Alkeran dosage: unknown. During the same period patient was treated with DEXAMETHASONE, HEMODIALYSIS. Patient was hospitalized. Patient died.

Alkeran Side Effects Report #5808328-5
Alkeran side effect was reported by a Consumer or non-health professional from RUSSIAN FEDERATION on June 25, 2008. Male patient, 50 years of age, was diagnosed with multiple myeloma  and was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, mucosal haemorrhage, myelodysplastic syndrome, pancytopenia, paroxysmal nocturnal haemoglobinuria, renal impairment, skin haemorrhage. Alkeran dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISOLONE, METHYLPREDNISOLONE, CYCLOPHOSPHAMIDE. Patient recovered.

Alkeran Side Effects Report #4993973-X
Alkeran side effect was reported by a Consumer or non-health professional from ISRAEL on Apr 24, 2006. Female patient, 44 years of age, weighting 176.4 lb, was diagnosed with malignant melanoma and was treated with Alkeran. After drug was administered, patient experienced the following side effects: amputation, blister, bone marrow failure, cyanosis, haematoma, leg amputation, necrosis, oedema, renal failure. Alkeran dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.


Alkeran Side Effects Report #5311547-8
Alkeran side effect was reported by a Consumer or non-health professional from FRANCE on Apr 19, 2007. Female patient, 78 years of age, weighting 103.6 lb, was treated with Alkeran. After drug was administered, patient experienced the following side effects: asthenia, bone marrow failure, pyrexia. Alkeran dosage: unknown. During the same period patient was treated with DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5833941-9
Alkeran side effect was reported by a Physician from JAPAN on Aug 05, 2008. Female patient, 60 years of age, was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, lung neoplasm malignant. Alkeran dosage: unknown. During the same period patient was treated with PREDONINE. Patient recovered.

Alkeran Side Effects Report #5848200-8
Alkeran side effect was reported by a Physician from JAPAN on Aug 12, 2008. Female patient, 60 years of age, was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, lung neoplasm malignant. Alkeran dosage: unknown. During the same period patient was treated with PREDONINE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5916530-7
Alkeran side effect was reported by a Physician from JAPAN on Oct 07, 2008. Female patient, 60 years of age, was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, lung neoplasm malignant. Alkeran dosage: unknown. During the same period patient was treated with PREDONINE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5950209-0
Alkeran side effect was reported by a Physician from JAPAN on Nov 06, 2008. Female patient, 60 years of age, was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, disease progression, lung neoplasm malignant. Alkeran dosage: unknown. During the same period patient was treated with PREDONINE. Patient was hospitalized. Patient died.


Alkeran Side Effects Report #5451427-0
Alkeran side effect was reported by a Consumer or non-health professional from FRANCE on Sept 03, 2007. Male patient, 57 years of age, was diagnosed with prophylaxis of nausea and vomiting and was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, cardiac disorder, cholestasis, hepatosplenomegaly, hyperthermia, liver function test abnormal, lung neoplasm, oxygen saturation decreased, pancytopenia. Alkeran dosage: 280MG SINGLE DOSE. During the same period patient was treated with RITUXAN, ZEVALIN, ETOPOSIDE, CYTARABINE, BICNU, KEPIVANCE, HEPARIN, ZOFRAN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5502930-6
Alkeran side effect was reported by a Consumer or non-health professional from FRANCE on Oct 22, 2007. Male patient, 57 years of age, was diagnosed with prophylaxis of nausea and vomiting and was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, cardiac disorder, cholestasis, hepatosplenomegaly, hyperthermia, liver function test abnormal, lung neoplasm, oxygen saturation decreased, pancytopenia. Alkeran dosage: 280MG SINGLE DOSE. During the same period patient was treated with MABTHERA, ZEVALIN, ETOPOSIDE, CYTARABINE, BICNU, KEPIVANCE, HEPARIN, ZOFRAN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5819195-8
Alkeran side effect was reported by a Physician from THAILAND on July 16, 2008. Female patient, 49 years of age, was treated with Alkeran. After drug was administered, patient experienced the following side effects: bone marrow failure, mucosal inflammation, nausea . Alkeran dosage: 100MG PER DAY. Patient recovered.

Alkeran Side Effects Report #5040415-4
Alkeran side effect was reported by a Consumer or non-health professional from FRANCE on June 20, 2006. Male patient, 44 years of age, was treated with Alkeran. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, bone marrow failure, gamma-glutamyltransferase increased, mucosal inflammation, transaminases increased. Alkeran dosage: 255MG PER DAY. During the same period patient was treated with BUSULFAN. Patient was hospitalized. Patient recovered.