Aldurazyme and vomiting Patient Reports February 12, 2012

Aldurazyme Side Effects Report #5259504-4
Aldurazyme side effect was reported by a Physician from UNITED STATES on Feb 20, 2007. Female patient, child 8 years of age, weighting 50.04 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: chills, lip swelling, pyrexia, tremor, vomiting. Aldurazyme dosage: unknown. During the same period patient was treated with BENADRYL, TYLENOL, HYDROCORTISONE. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5148811-1
Aldurazyme side effect was reported by a Physician from UNITED STATES on Sept 08, 2006. Female patient, child 8 years of age, weighting 50.04 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: antibody test positive, chills, infection , infusion related reaction, lip swelling, pyrexia, tremor, vomiting. Aldurazyme dosage: unknown. During the same period patient was treated with BENADRYL, TYLENOL, HYDROCORTISONE. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5297533-5
Aldurazyme side effect was reported by a Physician from COLOMBIA on Mar 21, 2007. Male patient, child 5 years of age, weighting 33.07 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cyanosis, diarrhoea, dyspnoea, pyrexia, tachypnoea, tremor, vomiting. Aldurazyme dosage: 0.58 MG/KG QWK IV. During the same period patient was treated with LEVOTIROXINE, LORATADINE. Patient recovered.

Aldurazyme Side Effects Report #5390730-X
Aldurazyme side effect was reported by a Physician from UNITED STATES on Dec 20, 2005. Female patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: dyspnoea, pyrexia, respiratory failure, speech disorder, viral infection , vomiting. Aldurazyme dosage: 0.6 MG/KG QWK IV. Patient was hospitalized. Patient died on 12/19/2005.


Aldurazyme Side Effects Report #4848119-5
Aldurazyme side effect was reported by a Physician from UNITED STATES on Nov 15, 2005. Female patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: dyspnoea, malaise, po2 decreased, pyrexia, viral infection , vomiting. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #4874096-7
Aldurazyme side effect was reported by a Physician from UNITED STATES on Dec 20, 2005. Female patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: dyspnoea, pyrexia, respiratory failure, speech disorder, viral infection , vomiting. Aldurazyme dosage: 0.6 MG/KG QWK IV. Patient was hospitalized. Patient died on 12/19/2005.

Aldurazyme Side Effects Report #5036059-0
Aldurazyme side effect was reported by a Physician from SPAIN on Feb 24, 2006. Male patient, child 5 years of age, weighting 33.07 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: vomiting. Aldurazyme dosage: MG/KG QWK IV. During the same period patient was treated with POLARAMINE, ACETAMINOPHEN. Patient recovered.

Aldurazyme Side Effects Report #5390242-3
Aldurazyme side effect was reported by a Physician from UNITED KINGDOM on Oct 17, 2006. Male patient, child 4 years of age, weighting 34.72 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: viral infection , vomiting. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5390755-4
Aldurazyme side effect was reported by a Physician from PORTUGAL on Sept 06, 2005. Female patient, child 3 years of age, weighting 26.46 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: angioedema, face oedema, nausea , prostration, pyrexia. Aldurazyme dosage: unknown. During the same period patient was treated with NEOSTIL. Patient was hospitalized. Patient recovered.


Aldurazyme Side Effects Report #5762050-2
Aldurazyme side effect was reported by a Physician from COLOMBIA on May 20, 2008. Female patient, child 3 years of age, weighting 26.46 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cyanosis, headache , hydrocephalus , infusion related reaction, oxygen saturation decreased, pneumonia , tachypnoea, vomiting. Aldurazyme dosage: 0.5 MG/KG, INTRAVENOUS. During the same period patient was treated with BECLOMETHASONE DIPROPIONATE, SALBUTAMOL, NIFEDIPINE, RANITIDINE, FUROSEMIDE, IPRATROPIUM BROMIDE. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5390974-7
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on Apr 02, 2007. Female patient, weighting 33.95 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: adrenal insufficiency, cardiac arrest , diarrhoea, disseminated intravascular coagulation, hypotension, septic shock, vomiting. Aldurazyme dosage: unknown. Patient died on 03/27/2007.

Aldurazyme Side Effects Report #4684000-2
Aldurazyme side effect was reported by a Physician from on Mar 04, 2005. Female patient was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: pyrexia, vomiting. Aldurazyme dosage: 0.58 MG/KG QWK IV. Patient recovered.