Aldurazyme and infusion related reaction 
Aldurazyme and infusion related reaction Patient Reports February 12, 2012
Aldurazyme Side Effects Report #4592662-3
Aldurazyme side effect was reported by a Physician from on Feb 04, 2005. Female patient, child 9 years of age, was diagnosed with mucopolysaccharidosis ih/s and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cardiac failure congestive, cardio-respiratory arrest, chest pain
, hypertension, hypertrophic cardiomyopathy, infusion related reaction, intercostal retraction, loss of consciousness, mitral valve incompetence. Aldurazyme dosage: 0.58 MG/KG QWK, IV. Patient was hospitalized. Patient died on 02/03/2005.Aldurazyme Side Effects Report #5448442-X
Aldurazyme side effect was reported by a Physician from UNITED STATES on Aug 23, 2007. Male patient, child 5 years of age, was diagnosed with mucopolysaccharidosis ih and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: abdominal pain
, angioedema, blood pressure diastolic decreased, cough, infusion related reaction, local swelling, oedema genital, oxygen saturation decreased, pruritus. Aldurazyme dosage: 8.7 MG QWK IV. During the same period patient was treated with HYDROCORTISONE, BENADRYL. Patient recovered.Aldurazyme Side Effects Report #6065420-0
Aldurazyme side effect was reported by a Physician from ARGENTINA on Jan 16, 2009. Female patient, child 9 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cyanosis, dyspnoea, face oedema, infusion related reaction, oxygen saturation decreased, rash
, tongue oedema. Aldurazyme dosage: 11.6 MG, 1X/W, INTRAVENOUS. Patient recovered.Aldurazyme Side Effects Report #5148811-1
Aldurazyme side effect was reported by a Physician from UNITED STATES on Sept 08, 2006. Female patient, child 8 years of age, weighting 50.04 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: antibody test positive, chills, infection
, infusion related reaction, lip swelling, pyrexia, tremor, vomiting. Aldurazyme dosage: unknown. During the same period patient was treated with BENADRYL, TYLENOL, HYDROCORTISONE. Patient was hospitalized. Patient recovered.Aldurazyme Side Effects Report #5624203-3
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on Jan 31, 2008. Female patient, child 7 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bacterial infection
, heart rate increased, infusion related reaction, pyrexia, respiratory arrest, respiratory distress. Aldurazyme dosage: 8.7 MG, 1X/W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ALBUTEROL, MOTRIN. Patient was hospitalized. Patient recovered.Aldurazyme Side Effects Report #5694209-7
Aldurazyme side effect was reported by a Physician from ECUADOR on Mar 17, 2008. Female patient, child 7 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, hepatomegaly, hypertension, infusion related reaction, irritability, pneumonia
, transaminases increased. Aldurazyme dosage: 0.58 MG/KG, 1X/W, INTRAVENOUS. During the same period patient was treated with ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE, FUROSEMIDE. Patient was hospitalized. Patient recovered.Aldurazyme Side Effects Report #5985306-7
Aldurazyme side effect was reported by a Consumer or non-health professional from ECUADOR on Nov 19, 2008. Female patient, child 7 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, hepatomegaly, hypertension, infusion related reaction, irritability, pneumonia
, transaminases increased. Aldurazyme dosage: 0.58 MG/KG, 1X/W, INTRAVENOUS. During the same period patient was treated with ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE, FUROSEMIDE. Patient died on 11/19/2008.Aldurazyme Side Effects Report #6081689-0
Aldurazyme side effect was reported by a Physician from TURKEY on Jan 30, 2009. Female patient, child 7 years of age, weighting 33.07 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactoid reaction, blood pressure diastolic decreased, chills, hypertension, infusion related reaction, pyrexia, tachycardia. Aldurazyme dosage: unknown. During the same period patient was treated with PREDNISOLONE, DIMENHYDRINATE. Patient was hospitalized. Patient recovered.
Aldurazyme Side Effects Report #5632954-X
Aldurazyme side effect was reported by a Physician from ECUADOR on Jan 31, 2008. Female patient, child 6 years of age, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, heart rate increased, hypertension, infusion related reaction, irritability, oxygen saturation decreased, respiratory rate increased, transaminases increased. Aldurazyme dosage: 0.58 MG/KG, QW,INTRAVENOUS. During the same period patient was treated with ENAPRIL, FUROSEMIDE. Patient recovered.
Aldurazyme Side Effects Report #6020709-6
Aldurazyme side effect was reported by a Physician from BRAZIL on Dec 05, 2008. Male patient, child 6 years of age, weighting 44.09 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: diarrhoea, infusion related reaction, pyrexia, sinusitis
, tachycardia, tachypnoea. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.Aldurazyme Side Effects Report #5292543-6
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on Mar 19, 2007. Male patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: abdominal pain
, blood pressure diastolic decreased, cough, dyspnoea, eye swelling, face oedema, infusion related reaction, oxygen saturation decreased. Aldurazyme dosage: 8.7 MG QWK IV. During the same period patient was treated with HYDROCORTISONE, BENADRYL. Patient recovered.Aldurazyme Side Effects Report #5924619-1
Aldurazyme side effect was reported by a Physician from UNITED STATES on Oct 02, 2008. Female patient, 41 years of age, weighting 88.18 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: headache
, hypoaesthesia, infusion related reaction, postoperative wound infection, rash . Aldurazyme dosage: 23.2 MG, 1X/W, INTRAVENOUS. Patient was hospitalized. Patient recovered.Aldurazyme Side Effects Report #5390263-0
Aldurazyme side effect was reported by a Physician from FRANCE on Oct 10, 2006. Male patient, child 4 years of age, weighting 37.48 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: face oedema, infusion related reaction, malaise, urticaria. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.
Aldurazyme Side Effects Report #5390989-9
Aldurazyme side effect was reported by a Physician from UNITED STATES on Mar 01, 2007. Female patient, 39 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: dyspnoea, infusion related reaction, oxygen saturation decreased, pyrexia, wheezing. Aldurazyme dosage: 0.58 MG/KG QWK IV. During the same period patient was treated with TYLENOL, CLARITIN. Patient recovered.
Aldurazyme Side Effects Report #5762050-2
Aldurazyme side effect was reported by a Physician from COLOMBIA on May 20, 2008. Female patient, child 3 years of age, weighting 26.46 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cyanosis, headache
, hydrocephalus , infusion related reaction, oxygen saturation decreased, pneumonia , tachypnoea, vomiting. Aldurazyme dosage: 0.5 MG/KG, INTRAVENOUS. During the same period patient was treated with BECLOMETHASONE DIPROPIONATE, SALBUTAMOL, NIFEDIPINE, RANITIDINE, FUROSEMIDE, IPRATROPIUM BROMIDE. Patient was hospitalized. Patient recovered.Aldurazyme Side Effects Report #5892232-0
Aldurazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 13, 2008. Male patient, child 2 years of age, weighting 26.46 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, bone marrow transplant
, ear tube insertion, infusion related reaction, neutropenia, pyrexia. Aldurazyme dosage: 5.8 MG, 1X/W, UNK. Patient recovered.Aldurazyme Side Effects Report #5855986-5
Aldurazyme side effect was reported by a Physician from UNITED STATES on Aug 08, 2008. Male patient, 18 years of age, weighting 198.4 lb, was diagnosed with mucopolysaccharidosis i, headache
, neck pain and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: congestive cardiomyopathy, disease progression, headache , hypersensitivity, infusion related reaction, intracranial pressure increased, myocardial fibrosis, neck pain. Aldurazyme dosage: 1.74 MG, ONCE, INTRATHECAL; INTRAVENOUS. During the same period patient was treated with DURAGESIC, BENADRYL, ADVIL. Patient died on 01/26/2008.Aldurazyme Side Effects Report #5390963-2
Aldurazyme side effect was reported by a Physician from UNITED STATES on Apr 24, 2007. Male patient, 14 years of age, weighting 59.75 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: blood pressure increased, c-reactive protein decreased, catheter related complication, infusion related reaction, international normalised ratio increased, protein total abnormal, prothrombin level increased, subclavian vein thrombosis, thrombin-antithrombin iii complex abnormal. Aldurazyme dosage: 15.7 MG QWK IV. During the same period patient was treated with ALBUTEROL, EAR DROPS, MIRALAX, ADVAIR DISKUS, FLONASE. Patient was hospitalized. Patient recovered.
Aldurazyme Side Effects Report #5920980-2
Aldurazyme side effect was reported by a Physician from BRAZIL on Oct 01, 2008. Male patient, child 11 years of age, weighting 101.4 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: dyspnoea, infusion related reaction, tachycardia, tachypnoea, urticaria. Aldurazyme dosage: 23.2 MG, 1X/W, INTRAVENOUS. Patient recovered.
Aldurazyme Side Effects Report #5036060-7
Aldurazyme side effect was reported by a Health Professional from UNITED KINGDOM on Feb 24, 2006. Female patient, child 10 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: infusion related reaction. Aldurazyme dosage: unknown. Patient recovered.
Aldurazyme Side Effects Report #5484835-2
Aldurazyme side effect was reported by a Physician from AUSTRALIA on Sept 26, 2007. Male patient, child 1 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactoid reaction, infusion related reaction. Aldurazyme dosage: unknown. Patient recovered.
Aldurazyme Side Effects Report #5594008-0
Aldurazyme side effect was reported by a Physician from FRANCE on Dec 27, 2007. Female patient, weighting 31.97 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: infusion related reaction, livedo reticularis, moaning, pyrexia. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.
Aldurazyme Side Effects Report #6050968-5
Aldurazyme side effect was reported by a Physician from TURKEY on Jan 07, 2009. Male patient, weighting 20.50 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, anaphylactoid reaction, flushing, hypotension, infusion related reaction, respiratory arrest, respiratory distress. Aldurazyme dosage: 5.8 MG, QW, INTRAVENOUS. Patient recovered.
Aldurazyme Side Effects Report #6125966-3
Aldurazyme side effect was reported by a Physician from TURKEY on Mar 06, 2009. Male patient, weighting 20.50 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, cyanosis, hypotension, infusion related reaction, respiratory arrest, respiratory distress. Aldurazyme dosage: 5.8 MG.,QW, INTRAVENOUS. Patient recovered.
Aldurazyme Side Effects Report #4727983-4
Aldurazyme side effect was reported by a Physician from UNITED KINGDOM on July 04, 2005. Female patient, weighting 17.86 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: blood pressure increased, fall
, floppy infant, infusion related reaction, oxygen saturation immeasurable, pallor, peripheral coldness. Aldurazyme dosage: unknown. During the same period patient was treated with ACETAMINOPHEN. Patient was hospitalized. Patient recovered.Aldurazyme Side Effects Report #6026158-9
Aldurazyme side effect was reported by a Physician from FRANCE on Dec 12, 2008. Male patient, child 3 years of age, was diagnosed with mucopolysaccharidosis and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: angioedema, conjunctivitis allergic, infusion related reaction, snoring
. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.Aldurazyme Side Effects Report #5624194-5
Aldurazyme side effect was reported by a Physician from UNITED STATES on Jan 26, 2008. Male patient, 18 years of age, weighting 198.4 lb, was diagnosed with mucopolysaccharidosis and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: headache
, hypersensitivity, infusion related reaction, intracranial pressure increased, neck pain. Aldurazyme dosage: 1.74 MG, ONCE, INTRATHECAL, INTRAVENOUS. During the same period patient was treated with BENADRYL, ADVIL. Patient died on 01/25/2008.Aldurazyme Side Effects Report #5675966-2
Aldurazyme side effect was reported by a Physician from UNITED STATES on Feb 29, 2008. Male patient, 18 years of age, weighting 198.4 lb, was diagnosed with mucopolysaccharidosis, neck pain and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: headache
, hypersensitivity, infusion related reaction, intracranial pressure increased, neck pain. Aldurazyme dosage: 1.74 MG ONCE INTRATHECAL. During the same period patient was treated with DURAGESIC, BENADRYL, ADVIL. Patient died on 01/26/2008.Aldurazyme Side Effects Report #5880674-9
Aldurazyme side effect was reported by a Physician from BRAZIL on Aug 28, 2008. Male patient, child 11 years of age, weighting 101.4 lb, was diagnosed with mucopolysaccharidosis and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: infusion related reaction, tachycardia, tachypnoea, urticaria. Aldurazyme dosage: 23.2 MG, 1X/W, INTRAVENOUS. Patient recovered.