Aldurazyme and hypersensitivity Patient Reports February 12, 2012

Aldurazyme Side Effects Report #5718726-6
Aldurazyme side effect was reported by a Physician from NORWAY on Apr 09, 2008. Female patient, child 8 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: blood pressure increased, body temperature decreased, chills, heart rate increased, hypersensitivity, pallor, peripheral coldness. Aldurazyme dosage: unknown. During the same period patient was treated with ZYRTEC. Patient recovered.

Aldurazyme Side Effects Report #4606911-6
Aldurazyme side effect was reported by a Physician from on Feb 22, 2005. Male patient, child 5 years of age, weighting 33.29 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: hepatic failure, hepatic necrosis, hepatitis a , hypersensitivity, hypoglycaemia. Aldurazyme dosage: 0.58 MG QWK IV. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5390993-0
Aldurazyme side effect was reported by a Physician from UNITED STATES on Jan 23, 2006. Female patient, child 4 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: brain stem glioma, deafness, head injury, hypersensitivity, pyrexia, swelling, umbilical hernia. Aldurazyme dosage: 0.58 MG/KG QWK IV. During the same period patient was treated with BACTRIM, PULMICORT, ZYRTEC, FLONASE, ALBUTEROL. Patient recovered.

Aldurazyme Side Effects Report #5989355-4
Aldurazyme side effect was reported by a Physician from TURKEY on Nov 21, 2008. Male patient, child 3 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: hypersensitivity, pyrexia, restlessness. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.


Aldurazyme Side Effects Report #6129669-0
Aldurazyme side effect was reported by a Physician from TURKEY on Mar 06, 2009. Male patient, child 3 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: hypersensitivity, pyrexia, restlessness. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5855986-5
Aldurazyme side effect was reported by a Physician from UNITED STATES on Aug 08, 2008. Male patient, 18 years of age, weighting 198.4 lb, was diagnosed with mucopolysaccharidosis i, headache , neck pain and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: congestive cardiomyopathy, disease progression, headache , hypersensitivity, infusion related reaction, intracranial pressure increased, myocardial fibrosis, neck pain. Aldurazyme dosage: 1.74 MG, ONCE, INTRATHECAL; INTRAVENOUS. During the same period patient was treated with DURAGESIC, BENADRYL, ADVIL. Patient died on 01/26/2008.

Aldurazyme Side Effects Report #5390194-6
Aldurazyme side effect was reported by a Physician from BRAZIL on Nov 30, 2006. Male patient, 13 years of age, weighting 55.89 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: dyspnoea, hypersensitivity, urticaria. Aldurazyme dosage: 25.5 ML QWK IV. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5918558-X
Aldurazyme side effect was reported by a Physician from TURKEY on Sept 26, 2008. Female patient, child 7 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: chills, hypersensitivity, hypertension, pyrexia, tachycardia. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5624194-5
Aldurazyme side effect was reported by a Physician from UNITED STATES on Jan 26, 2008. Male patient, 18 years of age, weighting 198.4 lb, was diagnosed with mucopolysaccharidosis and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: headache , hypersensitivity, infusion related reaction, intracranial pressure increased, neck pain. Aldurazyme dosage: 1.74 MG, ONCE, INTRATHECAL, INTRAVENOUS. During the same period patient was treated with BENADRYL, ADVIL. Patient died on 01/25/2008.


Aldurazyme Side Effects Report #5675966-2
Aldurazyme side effect was reported by a Physician from UNITED STATES on Feb 29, 2008. Male patient, 18 years of age, weighting 198.4 lb, was diagnosed with mucopolysaccharidosis, neck pain and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: headache , hypersensitivity, infusion related reaction, intracranial pressure increased, neck pain. Aldurazyme dosage: 1.74 MG ONCE INTRATHECAL. During the same period patient was treated with DURAGESIC, BENADRYL, ADVIL. Patient died on 01/26/2008.