Aldurazyme and condition aggravated Patient Reports February 12, 2012

Aldurazyme Side Effects Report #5920977-2
Aldurazyme side effect was reported by a Physician from GERMANY on Sept 30, 2008. Male patient, 46 years of age, weighting 141.1 lb, was diagnosed with mucopolysaccharidosis is and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bedridden, condition aggravated, disease progression, pain , refusal of treatment by patient, spinal column stenosis. Aldurazyme dosage: unknown. During the same period patient was treated with AMIODARONE, MORPHINE, HALOPERIDOL. Patient died on 09/17/2008.

Aldurazyme Side Effects Report #5390725-6
Aldurazyme side effect was reported by a Physician from FRANCE on May 02, 2006. Male patient, child 4 years of age, weighting 35.94 lb, was diagnosed with mucopolysaccharidosis ih and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bradycardia, bronchial disorder, cardiac arrest , condition aggravated, disease progression, ear congestion, ear disorder, hypercapnia. Aldurazyme dosage: 14.5 MG QWK IV. During the same period patient was treated with VENTOLIN. Patient was hospitalized. Patient died on 03/17/2006.

Aldurazyme Side Effects Report #5036467-8
Aldurazyme side effect was reported by a Physician from FRANCE on June 09, 2006. Male patient, child 4 years of age, weighting 35.94 lb, was diagnosed with mucopolysaccharidosis ih and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bradycardia, bronchopneumonia, bronchopneumopathy, cardiac arrest , condition aggravated, disease progression, hypercapnia, mucopolysaccharidosis ih, obstructive airways disorder. Aldurazyme dosage: 14.5 MG QWK IV. During the same period patient was treated with VENTOLIN. Patient was hospitalized. Patient died on 03/17/2006.

Aldurazyme Side Effects Report #4877347-8
Aldurazyme side effect was reported by a Physician from JAPAN on Dec 22, 2005. Female patient, weighting 24.25 lb, was diagnosed with mucopolysaccharidosis ih and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: condition aggravated, sleep apnoea syndrome. Aldurazyme dosage: unknown. During the same period patient was treated with FENTANYL CITRATE, PROPOFOL, SEVOFLURANE, CEFAZOLIN, FLOMOXEF. Patient was hospitalized. Patient recovered.


Aldurazyme Side Effects Report #5424872-7
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on Aug 09, 2007. Female patient, child 9 years of age, weighting 49.82 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , condition aggravated, coronary artery stenosis, ear infection , fatigue, irritability, muscular weakness, skin infection, staphylococcal infection . Aldurazyme dosage: 11.6 MG QWK IV. During the same period patient was treated with CIPRODEX, FLOXIN, BACTROBAN, SILVADENE. Patient died on 06/18/2007.

Aldurazyme Side Effects Report #5390717-7
Aldurazyme side effect was reported by a Physician from UNITED KINGDOM on May 15, 2006. Female patient, 26 years of age, weighting 110.2 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: condition aggravated, mitral valve stenosis, pregnancy , pulmonary hypertension . Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5486431-X
Aldurazyme side effect was reported by a Physician from UNITED STATES on Oct 02, 2007. Female patient, 23 years of age, weighting 127.2 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: condition aggravated, headache , intracranial pressure increased, nausea . Aldurazyme dosage: 0.58 MG/KG QWK IV. During the same period patient was treated with REQUIP, NADOLOL, ZYRTEC, NEURONTIN, TOPAMAX, ARICEPT. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5489208-4
Aldurazyme side effect was reported by a Physician from UNITED STATES on Oct 02, 2007. Female patient, 23 years of age, weighting 127.2 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: computerised tomogram abnormal, condition aggravated, headache , intracranial pressure increased, nausea , non-cardiac chest pain, post procedural complication, shunt occlusion. Aldurazyme dosage: 0.58 MG/KG QWK IV. During the same period patient was treated with TYLENOL, BENADRYL, REQUIP, NADOLOL, TOPAMAX, ARICEPT, NEURONTIN, ZYRTEC. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5923644-4
Aldurazyme side effect was reported by a Physician from SLOVAKIA (Slovak Republic) on Sept 29, 2008. Female patient, 15 years of age, weighting 77.16 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood creatine phosphokinase decreased, condition aggravated, corneal deposits, haematocrit decreased, haemoglobin decreased. Aldurazyme dosage: unknown. Patient recovered.


Aldurazyme Side Effects Report #5390720-7
Aldurazyme side effect was reported by a Physician from CANADA on Nov 07, 2006. Male patient, weighting 39.68 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bone marrow transplant , cardiac valve disease, condition aggravated, deafness, hydrocephalus , kyphoscoliosis. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5390721-9
Aldurazyme side effect was reported by a Physician from CANADA on May 30, 2006. Male patient, weighting 39.68 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cardiac valve disease, condition aggravated, deafness, hydrocephalus , kyphoscoliosis. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5390741-4
Aldurazyme side effect was reported by a Physician from JAPAN on Sept 15, 2005. Female patient, weighting 24.25 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: condition aggravated, sleep apnoea syndrome. Aldurazyme dosage: unknown. During the same period patient was treated with FENTANYL CITRATE, PROPOFOL, SEVOFLURANE, CEFAZOLIN, FLOMEXEF. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5480861-8
Aldurazyme side effect was reported by a Physician from UKRAINE on Sept 20, 2007. Female patient, weighting 33.07 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bronchitis chronic, condition aggravated, cyanosis, loss of consciousness, neurological symptom, pneumonia , procedural complication, respiratory failure. Aldurazyme dosage: 1 MG/KG 1XW IV. During the same period patient was treated with SUMAMED. Patient died on 09/18/2007.

Aldurazyme Side Effects Report #4848744-1
Aldurazyme side effect was reported by a Physician from JAPAN on Sept 15, 2005. Female patient, weighting 24.25 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: condition aggravated, sleep apnoea syndrome. Aldurazyme dosage: unknown. During the same period patient was treated with FENTANYL CITRATE, PROPOFOL, SEVOFLURANE, CEFAZOLIN, FLOMOXEF. Patient was hospitalized. Patient recovered.